1W88
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![BU of 1w88 by Molmil](/molmil-images/mine/1w88) | The crystal structure of pyruvate dehydrogenase E1(D180N,E183Q) bound to the peripheral subunit binding domain of E2 | Descriptor: | DIHYDROLIPOYLLYSINE-RESIDUE ACETYLTRANSFERASE COMPONENT OF PYRUVATE, MAGNESIUM ION, PYRUVATE DEHYDROGENASE E1 COMPONENT, ... | Authors: | Frank, R.A.W, Pratap, J.V, Pei, X.Y, Perham, R.N, Luisi, B.F. | Deposit date: | 2004-09-16 | Release date: | 2004-11-02 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | A Molecular Switch and Proton-Wire Synchronize the Active Sites in Thiamine-Dependent Enzymes Science, 306, 2004
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2JGD
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![BU of 2jgd by Molmil](/molmil-images/mine/2jgd) | E. COLI 2-oxoglutarate dehydrogenase (E1o) | Descriptor: | 2-OXOGLUTARATE DEHYDROGENASE E1 COMPONENT, ADENOSINE MONOPHOSPHATE | Authors: | Frank, R.A.W, Price, A.J, Northrop, F.D, Perham, R.N, Luisi, B.F. | Deposit date: | 2007-02-12 | Release date: | 2007-02-27 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal Structure of the E1 Component of the Escherichia Coli 2-Oxoglutarate Dehydrogenase Multienzyme Complex. J.Mol.Biol., 368, 2007
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2BP7
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![BU of 2bp7 by Molmil](/molmil-images/mine/2bp7) | New crystal form of the Pseudomonas putida branched-chain dehydrogenase (E1) | Descriptor: | 2-OXOISOVALERATE DEHYDROGENASE ALPHA SUBUNIT, 2-OXOISOVALERATE DEHYDROGENASE BETA SUBUNIT | Authors: | Frank, R.A.W, Pratap, J.V, Pei, X.Y, Perham, R.N, Luisi, B.F. | Deposit date: | 2005-04-18 | Release date: | 2005-08-10 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | The Molecular Origins of Specificity in the Assembly of a Multienzyme Complex. Structure, 13, 2005
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1W85
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![BU of 1w85 by Molmil](/molmil-images/mine/1w85) | The crystal structure of pyruvate dehydrogenase E1 bound to the peripheral subunit binding domain of E2 | Descriptor: | DI(HYDROXYETHYL)ETHER, DIHYDROLIPOYLLYSINE-RESIDUE ACETYLTRANSFERASE COMPONENT OF PYRUVATE, MAGNESIUM ION, ... | Authors: | Frank, R.A.W, Pratap, J.V, Pei, X.Y, Perham, R.N, Luisi, B.F. | Deposit date: | 2004-09-16 | Release date: | 2004-11-02 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A molecular switch and proton wire synchronize the active sites in thiamine enzymes. Science, 306, 2004
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8BFB
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![BU of 8bfb by Molmil](/molmil-images/mine/8bfb) | Sarkosyl-extracted AppNL-G-F Abeta42 fibril structure (Methoxy-X04-labelled mice) | Descriptor: | Amyloid-beta precursor protein | Authors: | Wilkinson, M, Leistner, C, Burgess, A, Goodfellow, S, Deuchars, S, Ranson, N.A, Radford, S.E, Frank, R.A.W. | Deposit date: | 2022-10-24 | Release date: | 2023-05-31 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | The in-tissue molecular architecture of beta-amyloid pathology in the mammalian brain. Nat Commun, 14, 2023
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8BFA
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![BU of 8bfa by Molmil](/molmil-images/mine/8bfa) | Sarkosyl-extracted AppNL-G-F Abeta42 fibril structure | Descriptor: | Amyloid-beta precursor protein | Authors: | Wilkinson, M, Leistner, C, Burgess, A, Goodfellow, S, Deuchars, S, Ranson, N.A, Radford, S.E, Frank, R.A.W. | Deposit date: | 2022-10-24 | Release date: | 2023-05-31 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | The in-tissue molecular architecture of beta-amyloid pathology in the mammalian brain. Nat Commun, 14, 2023
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6GBU
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![BU of 6gbu by Molmil](/molmil-images/mine/6gbu) | Crystal structure of the second SH3 domain of FCHSD2 (SH3-2) in complex with the fourth SH3 domain of ITSN1 (SH3d) | Descriptor: | F-BAR and double SH3 domains protein 2, Intersectin-1 | Authors: | Almeida-Souza, L, Frank, R, Garcia-Nafria, J, Colussi, A, Gunawardana, N, Johnson, C.M, Yu, M, Howard, G, Andrews, B, Vallis, Y, McMahon, H.T. | Deposit date: | 2018-04-16 | Release date: | 2018-06-13 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3.44 Å) | Cite: | A Flat BAR Protein Promotes Actin Polymerization at the Base of Clathrin-Coated Pits. Cell, 174, 2018
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3DVA
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![BU of 3dva by Molmil](/molmil-images/mine/3dva) | Snapshots of catalysis in the E1 subunit of the pyruvate dehydrogenase multi-enzyme complex | Descriptor: | 2-{4-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-3-METHYLTHIOPHEN-2-YL}ETHYL TRIHYDROGEN DIPHOSPHATE, Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, MAGNESIUM ION, ... | Authors: | Pei, X.Y, Titman, C.M, Frank, R.A.W, Leeper, F.J, Luisi, B.F. | Deposit date: | 2008-07-18 | Release date: | 2009-01-13 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Snapshots of catalysis in the e1 subunit of the pyruvate dehydrogenase multienzyme complex Structure, 16, 2008
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3DUF
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![BU of 3duf by Molmil](/molmil-images/mine/3duf) | Snapshots of catalysis in the E1 subunit of the pyruvate dehydrogenase multi-enzyme complex | Descriptor: | 2-{4-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-5-[(1R)-1-HYDROXYETHYL]-3-METHYL-2-THIENYL}ETHYL TRIHYDROGEN DIPHOSPHATE, Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, MAGNESIUM ION, ... | Authors: | Pei, X.Y, Titman, C.M, Frank, R.A.W, Leeper, F.J, Luisi, B.F. | Deposit date: | 2008-07-17 | Release date: | 2009-01-06 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Snapshots of catalysis in the e1 subunit of the pyruvate dehydrogenase multienzyme complex Structure, 16, 2008
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3DV0
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![BU of 3dv0 by Molmil](/molmil-images/mine/3dv0) | Snapshots of catalysis in the E1 subunit of the pyruvate dehydrogenase multi-enzyme complex | Descriptor: | 2-{4-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-3-METHYLTHIOPHEN-2-YL}ETHYL TRIHYDROGEN DIPHOSPHATE, Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, MAGNESIUM ION, ... | Authors: | Pei, X.Y, Titman, C.M, Frank, R.A.W, Leeper, F.J, Luisi, B.F. | Deposit date: | 2008-07-18 | Release date: | 2009-01-13 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Snapshots of catalysis in the e1 subunit of the pyruvate dehydrogenase multienzyme complex Structure, 16, 2008
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