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1EN5
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BU of 1en5 by Molmil
CRYSTAL STRUCTURE ANALYSIS OF THE E. COLI MANGANESE SUPEROXIDE DISMUTASE Y34F MUTANT
Descriptor: MANGANESE (II) ION, MANGANESE SUPEROXIDE DISMUTASE
Authors:Edwards, R.A, Whittaker, M.M, Baker, E.N, Whittaker, J.W, Jameson, G.B.
Deposit date:2000-03-20
Release date:2001-06-27
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Outer sphere mutations perturb metal reactivity in manganese superoxide dismutase.
Biochemistry, 40, 2001
1EN4
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BU of 1en4 by Molmil
CRYSTAL STRUCTURE ANALYSIS OF THE E. COLI MANGANESE SUPEROXIDE DISMUTASE Q146H MUTANT
Descriptor: MANGANESE (II) ION, MANGANESE SUPEROXIDE DISMUTASE
Authors:Edwards, R.A, Whittaker, M.M, Baker, E.N, Whittaker, J.W, Jameson, G.B.
Deposit date:2000-03-20
Release date:2001-06-27
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Outer sphere mutations perturb metal reactivity in manganese superoxide dismutase.
Biochemistry, 40, 2001
1EN6
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BU of 1en6 by Molmil
CRYSTAL STRUCTURE ANALYSIS OF THE E. COLI MANGANESE SUPEROXIDE DISMUTASE Q146L MUTANT
Descriptor: MANGANESE (II) ION, MANGANESE SUPEROXIDE DISMUTASE
Authors:Edwards, R.A, Whittaker, M.M, Baker, E.N, Whittaker, J.W, Jameson, G.B.
Deposit date:2000-03-20
Release date:2001-06-27
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Outer sphere mutations perturb metal reactivity in manganese superoxide dismutase.
Biochemistry, 40, 2001
1I08
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BU of 1i08 by Molmil
CRYSTAL STRUCTURE ANALYSIS OF THE H30A MUTANT OF MANGANESE SUPEROXIDE DISMUTASE FROM E. COLI
Descriptor: MANGANESE (II) ION, MANGANESE SUPEROXIDE DISMUTASE
Authors:Edwards, R.A, Whittaker, M.M, Whittaker, J.W, Baker, E.N, Jameson, G.B.
Deposit date:2001-01-29
Release date:2001-02-28
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Removing a hydrogen bond in the dimer interface of Escherichia coli manganese superoxide dismutase alters structure and reactivity.
Biochemistry, 40, 2001
1I0H
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BU of 1i0h by Molmil
CRYSTAL STRUCTURE OF THE E. COLI MANGANESE SUPEROXIDE DISMUTASE MUTANT Y174F AT 1.35 ANGSTROMS RESOLUTION.
Descriptor: MANGANESE (II) ION, MANGANESE SUPEROXIDE DISMUTASE Y174F MUTANT
Authors:Edwards, R.A, Whittaker, M.M, Whittaker, J.W, Baker, E.N, Jameson, G.B.
Deposit date:2001-01-29
Release date:2001-02-28
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Removing a hydrogen bond in the dimer interface of Escherichia coli manganese superoxide dismutase alters structure and reactivity.
Biochemistry, 40, 2001
1MMM
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BU of 1mmm by Molmil
DISTINCT METAL ENVIRONMENT IN IRON-SUBSTITUTED MANGANESE SUPEROXIDE DISMUTASE PROVIDES A STRUCTURAL BASIS OF METAL SPECIFICITY
Descriptor: FE (III) ION, HYDROXIDE ION, PROTEIN (IRON-SUBSTITUTED MANGANESE SUPEROXIDE DISMUTASE)
Authors:Edwards, R.A, Whittaker, M.M, Whittaker, J.W, Jameson, G.B, Baker, E.N.
Deposit date:1998-08-26
Release date:1998-09-02
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Distinct Metal Environment in Fe-Substituted Manganese Superoxide Dismutase Provides a Structural Basis of Metal Specificity
J.Am.Chem.Soc., 120, 1998
1VEW
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BU of 1vew by Molmil
MANGANESE SUPEROXIDE DISMUTASE FROM ESCHERICHIA COLI
Descriptor: HYDROXIDE ION, MANGANESE (II) ION, MANGANESE SUPEROXIDE DISMUTASE
Authors:Edwards, R.A, Baker, H.M, Whittaker, M.M, Whittaker, J.W, Jameson, G.B, Baker, E.N.
Deposit date:1998-01-20
Release date:1998-05-27
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of Escherichia coli manganese superoxide dismutase at 2.1-angstrom resolution.
J.Biol.Inorg.Chem., 3, 1998
9BIV
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BU of 9biv by Molmil
Crystal Structure of Ubc13 with a New Active Site Loop Conformation
Descriptor: Ubiquitin-conjugating enzyme E2 N, Ubiquitin-conjugating enzyme E2 variant 2
Authors:Farraj, R.A, Edwards, R.A, Glover, J.N.M.
Deposit date:2024-04-24
Release date:2024-05-08
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Crystal Structure of Ubc13 with a New Active Site Loop Conformation
To Be Published
8D34
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BU of 8d34 by Molmil
Crystal Structure of SARS CoV-2 NSP15 Endroribonuclease H250A
Descriptor: Uridylate-specific endoribonuclease nsp15
Authors:Farraj, R.A, Edwards, R.A, Glover, J.N.M.
Deposit date:2022-05-31
Release date:2023-06-14
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.91 Å)
Cite:Crystal Structure of SARS CoV-2 NSP15 Endroribonuclease H250A
To Be Published
2ADO
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BU of 2ado by Molmil
Crystal Structure Of The Brct Repeat Region From The Mediator of DNA damage checkpoint protein 1, MDC1
Descriptor: Mediator of DNA damage checkpoint protein 1
Authors:Lee, M.S, Edwards, R.A, Thede, G.L, Glover, J.N.
Deposit date:2005-07-20
Release date:2005-08-02
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structure of the BRCT Repeat Domain of MDC1 and Its Specificity for the Free COOH-terminal End of the {gamma}-H2AX Histone Tail.
J.Biol.Chem., 280, 2005
8UK7
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BU of 8uk7 by Molmil
Periplasmic domain of Escherichia coli CpxA
Descriptor: Sensor histidine kinase CpxA
Authors:Glover, M.J.N, Murray, C.R.A, Edwards, R.A, Thede, G.L.
Deposit date:2023-10-12
Release date:2023-10-25
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The sensor of the bacterial histidine kinase CpxA is a novel dimer of extracytoplasmic Per-ARNT-Sim domains.
J.Biol.Chem., 300, 2024
4WHV
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BU of 4whv by Molmil
E3 ubiquitin-protein ligase RNF8 in complex with Ubiquitin-conjugating enzyme E2 N and Polyubiquitin-B
Descriptor: E3 ubiquitin-protein ligase RNF8, Polyubiquitin-B, Ubiquitin-conjugating enzyme E2 N, ...
Authors:Hodge, C.D, Edwards, R.A, Glover, J.N.M.
Deposit date:2014-09-23
Release date:2015-09-30
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (8.3 Å)
Cite:RNF8 E3 Ubiquitin Ligase Stimulates Ubc13 E2 Conjugating Activity That Is Essential for DNA Double Strand Break Signaling and BRCA1 Tumor Suppressor Recruitment.
J.Biol.Chem., 291, 2016
1IX9
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BU of 1ix9 by Molmil
Crystal Structure of the E. coli Manganase(III) superoxide dismutase mutant Y174F at 0.90 angstroms resolution.
Descriptor: MANGANESE (II) ION, Superoxide Dismutase
Authors:Anderson, B.F, Edwards, R.A, Whittaker, M.M, Whittaker, J.W, Baker, E.N, Jameson, G.B.
Deposit date:2002-06-17
Release date:2002-12-17
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (0.9 Å)
Cite:Structures at 0.90 A resolution of the oxidised and reduced forms of the Y174F mutant of the manganese superoxide dismutase from Escherichia coli
To be Published
1IXB
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BU of 1ixb by Molmil
CRYSTAL STRUCTURE OF THE E. COLI MANGANESE(II) SUPEROXIDE DISMUTASE MUTANT Y174F AT 0.90 ANGSTROMS RESOLUTION.
Descriptor: MANGANESE ION, 1 HYDROXYL COORDINATED, SUPEROXIDE DISMUTASE
Authors:Anderson, B.F, Edwards, R.A, Whittaker, M.M, Whittaker, J.W, Baker, E.N, Jameson, G.B.
Deposit date:2002-06-18
Release date:2002-12-18
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (0.9 Å)
Cite:Structures at 0.90 A resolution of the oxidised and reduced forms of the Y174F mutant of the manganese superoxide dismutase from Escherichia coli
To be Published
4QPQ
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BU of 4qpq by Molmil
Mechanistic basis of plasmid-specific DNA binding of the F plasmid regulatory protein, TraM
Descriptor: Relaxosome protein TraM, sbmA DNA1, sbmA DNA2
Authors:Peng, Y, Lu, J, Wong, J, Edwards, R.A, Frost, L.S, Glover, J.N.M.
Deposit date:2014-06-24
Release date:2014-09-24
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.106 Å)
Cite:Mechanistic Basis of Plasmid-Specific DNA Binding of the F Plasmid Regulatory Protein, TraM.
J.Mol.Biol., 426, 2014
1J74
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BU of 1j74 by Molmil
Crystal Structure of Mms2
Descriptor: MMS2
Authors:Moraes, T.F, Edwards, R.A, McKenna, S, Pastushok, L, Xiao, W, Glover, J.N.M, Ellison, M.J.
Deposit date:2001-05-15
Release date:2001-08-08
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of the human ubiquitin conjugating enzyme complex, hMms2-hUbc13.
Nat.Struct.Biol., 8, 2001
1J7D
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BU of 1j7d by Molmil
Crystal Structure of hMms2-hUbc13
Descriptor: MMS2, UBIQUITIN-CONJUGATING ENZYME E2-17 KDA
Authors:Moraes, T.F, Edwards, R.A, McKenna, S, Pashushok, L, Xiao, W, Glover, J.N.M, Ellison, M.J.
Deposit date:2001-05-16
Release date:2001-08-08
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structure of the human ubiquitin conjugating enzyme complex, hMms2-hUbc13.
Nat.Struct.Biol., 8, 2001
4ONM
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BU of 4onm by Molmil
Crystal structure of human Mms2/Ubc13 - NSC697923
Descriptor: 2-[(4-methylphenyl)sulfonyl]-5-nitrofuran, GLYCEROL, Ubiquitin-conjugating enzyme E2 N, ...
Authors:Hodge, C.D, Edwards, R.A, Glover, J.N.M.
Deposit date:2014-01-28
Release date:2015-05-06
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Covalent Inhibition of Ubc13 Affects Ubiquitin Signaling and Reveals Active Site Elements Important for Targeting.
Acs Chem.Biol., 10, 2015
4ONN
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BU of 4onn by Molmil
Crystal structure of human Mms2/Ubc13 - BAY 11-7082
Descriptor: 3-[(4-methylphenyl)sulfonyl]prop-2-enenitrile, GLYCEROL, Ubiquitin-conjugating enzyme E2 N, ...
Authors:Hodge, C.D, Edwards, R.A, Glover, J.N.M.
Deposit date:2014-01-28
Release date:2015-05-06
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Covalent Inhibition of Ubc13 Affects Ubiquitin Signaling and Reveals Active Site Elements Important for Targeting.
Acs Chem.Biol., 10, 2015
4OFB
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BU of 4ofb by Molmil
Crystal structure of human BRCA1 BRCT in complex with nonphosphopeptide inhibitor
Descriptor: Breast cancer type 1 susceptibility protein, nonphosphopeptide inhibitor
Authors:Sun, L, Edwards, R.A, Glover, J.N.M.
Deposit date:2014-01-14
Release date:2015-04-15
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Peptide Library Approach to Uncover Phosphomimetic Inhibitors of the BRCA1 C-Terminal Domain.
Acs Chem.Biol., 10, 2015
4ONL
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BU of 4onl by Molmil
Crystal structure of human Mms2/Ubc13_D81N, R85S, A122V, N123P
Descriptor: Ubiquitin-conjugating enzyme E2 N, Ubiquitin-conjugating enzyme E2 variant 2
Authors:Hodge, C.D, Edwards, R.A, Glover, J.N.M.
Deposit date:2014-01-28
Release date:2015-05-06
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Covalent Inhibition of Ubc13 Affects Ubiquitin Signaling and Reveals Active Site Elements Important for Targeting.
Acs Chem.Biol., 10, 2015
4ORH
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BU of 4orh by Molmil
Crystal structure of RNF8 bound to the UBC13/MMS2 heterodimer
Descriptor: E3 ubiquitin-protein ligase RNF8, Ubiquitin-conjugating enzyme E2 N, Ubiquitin-conjugating enzyme E2 variant 2, ...
Authors:Campbell, S.J, Edwards, R.A, Glover, J.N.M.
Deposit date:2014-02-11
Release date:2014-02-26
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (4.802 Å)
Cite:Molecular insights into the function of RING finger (RNF)-containing proteins hRNF8 and hRNF168 in Ubc13/Mms2-dependent ubiquitylation.
J.Biol.Chem., 287, 2012
4QPO
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BU of 4qpo by Molmil
Mechanistic basis of plasmid-specific DNA binding of the F plasmid regulatory protein, TraM
Descriptor: PHOSPHATE ION, Relaxosome protein TraM
Authors:Peng, Y, Lu, J, Wong, J, Edwards, R.A, Frost, L.S, Glover, J.N.M.
Deposit date:2014-06-24
Release date:2014-09-03
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.999 Å)
Cite:Mechanistic Basis of Plasmid-Specific DNA Binding of the F Plasmid Regulatory Protein, TraM.
J.Mol.Biol., 426, 2014
2F9D
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BU of 2f9d by Molmil
2.5 angstrom resolution structure of the spliceosomal protein p14 bound to region of SF3b155
Descriptor: Pre-mRNA branch site protein p14, Splicing factor 3B subunit 1
Authors:Schellenberg, M.J, Edwards, R.A, Ritchie, D.B, Glover, J.N.M, Macmillan, A.M.
Deposit date:2005-12-05
Release date:2006-01-24
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of a core spliceosomal protein interface
Proc.Natl.Acad.Sci.Usa, 103, 2006
3K16
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BU of 3k16 by Molmil
Crystal Structure of BRCA1 BRCT D1840T in complex with a minimal recognition tetrapeptide with a free carboxy C-terminus
Descriptor: Breast cancer type 1 susceptibility protein, CHLORIDE ION, NICKEL (II) ION, ...
Authors:Campbell, S.J, Edwards, R.A, Glover, J.N.
Deposit date:2009-09-25
Release date:2010-03-02
Last modified:2021-10-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Comparison of the Structures and Peptide Binding Specificities of the BRCT Domains of MDC1 and BRCA1
Structure, 18, 2010

 

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