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7S16
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BU of 7s16 by Molmil
Crystal structure of alpha-COP-WD40 domain R57A mutant
Descriptor: Coatomer subunit alpha, SODIUM ION
Authors:Dey, D, Singh, S, Khan, S, Martin, M, Schnicker, N, Gakhar, L, Pierce, B, Hasan, S.S.
Deposit date:2021-09-01
Release date:2022-02-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.24 Å)
Cite:An extended motif in the SARS-CoV-2 spike modulates binding and release of host coatomer in retrograde trafficking
Commun Biol, 5, 2022
7S22
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BU of 7s22 by Molmil
Crystal structure of alpha-COP-WD40 domain
Descriptor: Coatomer subunit alpha
Authors:Dey, D, Singh, S, Khan, S, Martin, M, Schnicker, N, Gakhar, L, Pierce, B, Hasan, S.S.
Deposit date:2021-09-02
Release date:2022-02-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:An extended motif in the SARS-CoV-2 spike modulates binding and release of host coatomer in retrograde trafficking
Commun Biol, 5, 2022
7S23
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BU of 7s23 by Molmil
Crystal structure of alpha-COP-WD40 domain, Y139A mutant
Descriptor: Coatomer subunit alpha
Authors:Dey, D, Singh, S, Khan, S, Martin, M, Schnicker, N, Gakhar, L, Pierce, B, Hasan, S.S.
Deposit date:2021-09-03
Release date:2022-02-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:An extended motif in the SARS-CoV-2 spike modulates binding and release of host coatomer in retrograde trafficking
Commun Biol, 5, 2022
7Y5Y
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BU of 7y5y by Molmil
X-ray Structure of Stay-Green (SGR) from Anaerolineae bacterium.
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, PHOSPHATE ION, ...
Authors:Dey, D, Nishijima, M, Kurisu, G, Tanaka, H, Ito, H.
Deposit date:2022-06-18
Release date:2022-10-19
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structure and reaction mechanism of a bacterial Mg-dechelatase homolog from the Chloroflexi Anaerolineae.
Protein Sci., 31, 2022
5KZK
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BU of 5kzk by Molmil
Crystal Structure of rRNA methyltransferase from Sinorhizobium meliloti
Descriptor: COBALT (II) ION, Probable RNA methyltransferase, TrmH family, ...
Authors:Dey, D, Hegde, R.P, Almo, S.C, Ramakumar, S, Ramagopal, U.A, New York Structural Genomics Research Consortium (NYSGRC)
Deposit date:2016-07-25
Release date:2017-08-02
Last modified:2019-11-20
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Crystal Structure of rRNA methyltransferase from Sinorhizobium meliloti
To Be Published
5L0Z
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BU of 5l0z by Molmil
Crystal Structure of AdoMet bound rRNA methyltransferase from Sinorhizobium meliloti
Descriptor: COBALT (II) ION, Probable RNA methyltransferase, TrmH family, ...
Authors:Dey, D, Hegde, R.P, Almo, S.C, Ramakumar, S, Ramagopal, U.A.
Deposit date:2016-07-28
Release date:2017-08-02
Last modified:2019-11-20
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal Structure of AdoMet bound rRNA methyltransferase from Sinorhizobium meliloti
To Be Published
8SZX
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BU of 8szx by Molmil
Crystal structure of b'-WD40 Lys17Ala mutant
Descriptor: Coatomer subunit beta'
Authors:Dey, D, Hasan, S.S.
Deposit date:2023-05-30
Release date:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:A single C-terminal residue controls SARS-CoV-2 spike trafficking and incorporation into VLPs.
Nat Commun, 14, 2023
8F0E
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BU of 8f0e by Molmil
N-terminal WD40 domain of beta'-COPI subunit with four chains in the asymmetric unit
Descriptor: Coatomer subunit beta'
Authors:Dey, D, Hasan, S.S.
Deposit date:2022-11-02
Release date:2023-08-30
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.31 Å)
Cite:Strategies for rapid production of crystallization quality coatomer WD40 domains.
Protein Expr.Purif., 212, 2023
8EVL
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BU of 8evl by Molmil
Crystal structure of alpha-COPI N-terminal WD40 domain
Descriptor: Putative coatomer subunit alpha
Authors:Dey, D, Hasan, S.S.
Deposit date:2022-10-20
Release date:2023-08-30
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Strategies for rapid production of crystallization quality coatomer WD40 domains.
Protein Expr.Purif., 212, 2023
8EWX
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BU of 8ewx by Molmil
N-terminal WD40 domain of beta'-COPI subunit with two chains in the asymmetric unit
Descriptor: Coatomer subunit beta'
Authors:Dey, D, Hasan, S.S.
Deposit date:2022-10-24
Release date:2023-08-30
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.24 Å)
Cite:Strategies for rapid production of crystallization quality coatomer WD40 domains.
Protein Expr.Purif., 212, 2023
8ENZ
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BU of 8enz by Molmil
Crystal structure of alpha-COPI-WD40 domain K15A mutant.
Descriptor: ACETYL GROUP, Putative coatomer subunit alpha
Authors:Dey, D, Hasan, S.S.
Deposit date:2022-09-30
Release date:2024-01-31
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:A single C-terminal residue controls SARS-CoV-2 spike trafficking and incorporation into VLPs.
Nat Commun, 14, 2023
8ENY
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BU of 8eny by Molmil
Crystal structure of alpha-COPI-WD40 domain R13A mutant.
Descriptor: ACETYL GROUP, Putative coatomer subunit alpha
Authors:Dey, D, Hasan, S.S.
Deposit date:2022-09-30
Release date:2024-01-31
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A single C-terminal residue controls SARS-CoV-2 spike trafficking and incorporation into VLPs.
Nat Commun, 14, 2023
8ENX
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BU of 8enx by Molmil
Crystal structure of beta'-COPI-WD40 domain Y33A mutant in complex with SARS-CoV-2 clientized spike tail heptapeptide.
Descriptor: Clientized spike tail heptapeptide, Coatomer subunit beta'
Authors:Dey, D, Hasan, S.S.
Deposit date:2022-09-30
Release date:2024-01-31
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A single C-terminal residue controls SARS-CoV-2 spike trafficking and incorporation into VLPs.
Nat Commun, 14, 2023
8EO0
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BU of 8eo0 by Molmil
Crystal structure of alpha-COPI WD40 domain R300A mutant.
Descriptor: ACETYL GROUP, Putative coatomer subunit alpha
Authors:Dey, D, Hasan, S.S.
Deposit date:2022-10-01
Release date:2024-01-31
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A single C-terminal residue controls SARS-CoV-2 spike trafficking and incorporation into VLPs.
Nat Commun, 14, 2023
8ENS
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BU of 8ens by Molmil
Crystal structure of beta'-COPI-WD40 domain in complex with SARS-CoV-2 spike tail hepta-peptide
Descriptor: Coatomer subunit beta', spike tail hepta-peptide
Authors:Dey, D, Hasan, S.S.
Deposit date:2022-09-30
Release date:2024-01-31
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:A single C-terminal residue controls SARS-CoV-2 spike trafficking and incorporation into VLPs.
Nat Commun, 14, 2023
8ENW
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BU of 8enw by Molmil
Crystal structure of beta'-COPI-WD40 domain in complex with SARS-CoV-2 clientized spike tail heptapeptide.
Descriptor: 1,2-ETHANEDIOL, Clientized spike tail peptide, Coatomer subunit beta'
Authors:Dey, D, Hasan, S.S.
Deposit date:2022-09-30
Release date:2024-01-31
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:A single C-terminal residue controls SARS-CoV-2 spike trafficking and incorporation into VLPs.
Nat Commun, 14, 2023
8JQU
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BU of 8jqu by Molmil
Crystal structure of GppNHp bound GTPase domain of Rab5a from Leishmania donovani
Descriptor: 1,2-ETHANEDIOL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Pandey, D, Zohib, M, Pal, R.K, Biswal, B.K, Arora, A.
Deposit date:2023-06-14
Release date:2024-06-19
Method:X-RAY DIFFRACTION (1.798 Å)
Cite:Crystal structure of GppNHp bound GTPase domain of Rab5a from Leishmania donovani
To Be Published
7S0S
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BU of 7s0s by Molmil
M. tuberculosis ribosomal RNA methyltransferase TlyA bound to M. smegmatis 50S ribosomal subunit
Descriptor: 16S/23S rRNA (Cytidine-2'-O)-methyltransferase TlyA, 23S rRNA, 50S ribosomal protein L10, ...
Authors:Laughlin, Z.T, Dunham, C.M, Conn, G.L.
Deposit date:2021-08-31
Release date:2022-03-30
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.05 Å)
Cite:50S subunit recognition and modification by the Mycobacterium tuberculosis ribosomal RNA methyltransferase TlyA.
Proc.Natl.Acad.Sci.USA, 119, 2022
6PQB
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BU of 6pqb by Molmil
Crystal structure of aminoglycoside-resistance methyltransferase RmtC bound to S-adenosylhomocysteine (SAH)
Descriptor: 16S rRNA (guanine(1405)-N(7))-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Nosrati, M, Hoffer, E.D, Conn, G.L.
Deposit date:2019-07-08
Release date:2019-10-16
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.14 Å)
Cite:Functionally critical residues in the aminoglycoside resistance-associated methyltransferase RmtC play distinct roles in 30S substrate recognition.
J.Biol.Chem., 294, 2019
6ZGC
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BU of 6zgc by Molmil
Crystal structure of the ACVR1 (ALK2) kinase in complex with the compound Saracatinib (AZD0530)
Descriptor: Activin receptor type I, N-(5-CHLORO-1,3-BENZODIOXOL-4-YL)-7-[2-(4-METHYLPIPERAZIN-1-YL)ETHOXY]-5-(TETRAHYDRO-2H-PYRAN-4-YLOXY)QUINAZOLIN-4-AMINE, PHOSPHATE ION, ...
Authors:Williams, E.P, Galan Bartual, S, Burgess-Brown, N, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A.N.
Deposit date:2020-06-18
Release date:2020-07-29
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.67 Å)
Cite:Saracatinib is an efficacious clinical candidate for fibrodysplasia ossificans progressiva.
JCI Insight, 6, 2021
8CA0
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BU of 8ca0 by Molmil
Macrophage inhibitory factor (MIF) in complex with small molecule PAV174
Descriptor: 1-ethyl-9-methyl-3,7-dipyrrolidin-1-yl-phenothiazine, Macrophage migration inhibitory factor
Authors:Mueller, A, Torres, F, Roland, R, Korth, C.
Deposit date:2023-01-24
Release date:2024-02-07
Method:SOLUTION NMR
Cite:Oxidized MIF is a drug target at the molecular intersection between immune activation and tau cellular pathology
To Be Published
4RFL
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BU of 4rfl by Molmil
Crystal structure of G1PDH with NADPH from Methanocaldococcus jannaschii
Descriptor: 1,2-ETHANEDIOL, Glycerol-1-phosphate dehydrogenase [NAD(P)+], NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Carbone, V, Ronimus, R.S, Schofield, L.R, Sutherland-Smith, A.J.
Deposit date:2014-09-26
Release date:2015-07-22
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure and Evolution of the Archaeal Lipid Synthesis Enzyme sn-Glycerol-1-phosphate Dehydrogenase.
J.Biol.Chem., 290, 2015
4RGQ
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BU of 4rgq by Molmil
Crystal structure of the Methanocaldococcus jannaschii G1PDH with NADPH and DHAP
Descriptor: 1,2-ETHANEDIOL, 1,3-DIHYDROXYACETONEPHOSPHATE, Glycerol-1-phosphate dehydrogenase, ...
Authors:Carbone, V, Ronimus, R.S, Schofield, L.R, Sutherland-Smith, A.J.
Deposit date:2014-09-30
Release date:2015-07-22
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Structure and Evolution of the Archaeal Lipid Synthesis Enzyme sn-Glycerol-1-phosphate Dehydrogenase.
J.Biol.Chem., 290, 2015
4RGV
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BU of 4rgv by Molmil
Crystal structure of the Methanocaldococcus jannaschii G1PDH
Descriptor: Glycerol-1-phosphate dehydrogenase, MAGNESIUM ION, ZINC ION
Authors:Carbone, V, Ronimus, R.S, Schofield, L.R, Sutherland-Smith, A.J.
Deposit date:2014-09-30
Release date:2015-07-22
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structure and Evolution of the Archaeal Lipid Synthesis Enzyme sn-Glycerol-1-phosphate Dehydrogenase.
J.Biol.Chem., 290, 2015
8GHU
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BU of 8ghu by Molmil
Methyltransferase RmtC bound to the 30S ribosomal subunit
Descriptor: 16S rRNA, 16S rRNA (guanine(1405)-N(7))-methyltransferase, 30S ribosomal protein S12, ...
Authors:Srinivas, P, Conn, G.L, Dunham, C.M.
Deposit date:2023-03-12
Release date:2023-04-12
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3 Å)
Cite:30S subunit recognition and G1405 modification by the aminoglycoside-resistance 16S ribosomal RNA methyltransferase RmtC.
Biorxiv, 2023

 

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