Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
7C3V
DownloadVisualize
BU of 7c3v by Molmil
Structure of a thermostable Alcohol dehydrogenase from Kluyveromyces polyspora(KpADH)
Descriptor: Alcohol dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Dai, W, Ni, Y, Xu, G, Liu, Y, Wang, Y, Zhou, J.
Deposit date:2020-05-14
Release date:2021-05-19
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.20042944 Å)
Cite:Structure of a thermostable Alcohol dehydrogenase from Kluyveromyces polyspora(KpADH)
To Be Published
1D5S
DownloadVisualize
BU of 1d5s by Molmil
CRYSTAL STRUCTURE OF CLEAVED ANTITRYPSIN POLYMER
Descriptor: P1-ARG ANTITRYPSIN
Authors:Dunstone, M.A, Dai, W, Whisstock, J.C, Rossjohn, J, Pike, R.N, Feil, S.C, Le Bonneic, B.F, Parker, M.W, Bottomley, S.P.
Deposit date:1999-10-11
Release date:2000-04-02
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3 Å)
Cite:Cleaved antitrypsin polymers at atomic resolution.
Protein Sci., 9, 2000
7DNC
DownloadVisualize
BU of 7dnc by Molmil
Crystal structure of EV71 3C proteinase in complex with a novel inhibitor
Descriptor: 3C protease, ~{N}-[(2~{S})-3-cyclohexyl-1-oxidanylidene-1-[[(2~{S})-1-oxidanylidene-3-[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]propan-2-yl]amino]propan-2-yl]-1~{H}-indole-2-carboxamide
Authors:Xie, H, Su, H.X, Li, M.J, Xu, Y.C.
Deposit date:2020-12-09
Release date:2021-05-05
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.17 Å)
Cite:Design, Synthesis, and Biological Evaluation of Peptidomimetic Aldehydes as Broad-Spectrum Inhibitors against Enterovirus and SARS-CoV-2.
J.Med.Chem., 65, 2022
6MHB
DownloadVisualize
BU of 6mhb by Molmil
Glutathione S-Transferase Omega 1 bound to covalent inhibitor 18
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Glutathione S-transferase omega-1, N-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]propanamide
Authors:Petrunak, E.M, Stuckey, J.A.
Deposit date:2018-09-17
Release date:2019-02-20
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structure-Based Design of N-(5-Phenylthiazol-2-yl)acrylamides as Novel and Potent Glutathione S-Transferase Omega 1 Inhibitors.
J. Med. Chem., 62, 2019
6MHD
DownloadVisualize
BU of 6mhd by Molmil
Glutathione S-Transferase Omega 1 bound to covalent inhibitor 44
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ACETONE, Glutathione S-transferase omega-1, ...
Authors:Petrunak, E.M, Stuckey, J.A.
Deposit date:2018-09-17
Release date:2019-02-20
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Structure-Based Design of N-(5-Phenylthiazol-2-yl)acrylamides as Novel and Potent Glutathione S-Transferase Omega 1 Inhibitors.
J. Med. Chem., 62, 2019
6MHC
DownloadVisualize
BU of 6mhc by Molmil
Glutathione S-Transferase Omega 1 bound to covalent inhibitor 37
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, DIMETHYL SULFOXIDE, ...
Authors:Petrunak, E.M, Stuckey, J.A.
Deposit date:2018-09-17
Release date:2019-02-20
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure-Based Design of N-(5-Phenylthiazol-2-yl)acrylamides as Novel and Potent Glutathione S-Transferase Omega 1 Inhibitors.
J. Med. Chem., 62, 2019
6M0K
DownloadVisualize
BU of 6m0k by Molmil
The crystal structure of COVID-19 main protease in complex with an inhibitor 11b
Descriptor: 3C-like proteinase, DIMETHYL SULFOXIDE, ~{N}-[(2~{S})-3-(3-fluorophenyl)-1-oxidanylidene-1-[[(2~{S})-1-oxidanylidene-3-[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]propan-2-yl]amino]propan-2-yl]-1~{H}-indole-2-carboxamide
Authors:Zhang, B, Zhao, Y, Jin, Z, Liu, X, Yang, H, Liu, H, Rao, Z, Jiang, H.
Deposit date:2020-02-22
Release date:2020-04-29
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.504 Å)
Cite:Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease.
Science, 368, 2020
6LZE
DownloadVisualize
BU of 6lze by Molmil
The crystal structure of COVID-19 main protease in complex with an inhibitor 11a
Descriptor: 3C-like proteinase, DIMETHYL SULFOXIDE, ~{N}-[(2~{S})-3-cyclohexyl-1-oxidanylidene-1-[[(2~{S})-1-oxidanylidene-3-[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]propan-2-yl]amino]propan-2-yl]-1~{H}-indole-2-carboxamide
Authors:Zhang, B, Zhang, Y, Jing, Z, Liu, X, Yang, H, Liu, H, Rao, Z, Jiang, H.
Deposit date:2020-02-19
Release date:2020-04-29
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.505 Å)
Cite:Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease.
Science, 368, 2020
4AAH
DownloadVisualize
BU of 4aah by Molmil
METHANOL DEHYDROGENASE FROM METHYLOPHILUS W3A1
Descriptor: CALCIUM ION, METHANOL DEHYDROGENASE, PYRROLOQUINOLINE QUINONE
Authors:Mathews, F.S, Xia, Z.-X.
Deposit date:1996-03-10
Release date:1996-12-07
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Determination of the gene sequence and the three-dimensional structure at 2.4 angstroms resolution of methanol dehydrogenase from Methylophilus W3A1.
J.Mol.Biol., 259, 1996
8OH7
DownloadVisualize
BU of 8oh7 by Molmil
Structure of A4M4C bound to (KR)4 Solution backbone structure refined by PCS
Descriptor: Designed Armadillo repeat protein with four internal modules
Authors:Cucuzza, S, Zerbe, O.
Deposit date:2023-03-20
Release date:2023-12-13
Method:SOLUTION NMR
Cite:Unexpected dynamics in femtomolar complexes of binding proteins with peptides.
Nat Commun, 14, 2023
7N3V
DownloadVisualize
BU of 7n3v by Molmil
Crystal structure of Mycobacterium smegmatis LmcA
Descriptor: GLYCEROL, LmcA, SULFATE ION
Authors:Patel, O, Lucet, I, Panjikar, S.
Deposit date:2021-06-02
Release date:2022-04-13
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Crystal structure of the putative cell-wall lipoglycan biosynthesis protein LmcA from Mycobacterium smegmatis.
Acta Crystallogr D Struct Biol, 78, 2022
5CDZ
DownloadVisualize
BU of 5cdz by Molmil
Crystal structure of conserpin in the latent state
Descriptor: Conserpin in the latent state, GLYCEROL
Authors:Porebski, B.T, McGowan, S, Keleher, S, Buckle, A.M.
Deposit date:2015-07-06
Release date:2016-07-20
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.449 Å)
Cite:Smoothing a rugged protein folding landscape by sequence-based redesign.
Sci Rep, 6, 2016
5CE0
DownloadVisualize
BU of 5ce0 by Molmil
Crystal structure of conserpin with Z-mutation
Descriptor: Native conserpin with Z-variant (E342K)
Authors:Porebski, B.T, McGowan, S, Keleher, S, Buckle, A.M.
Deposit date:2015-07-06
Release date:2016-07-20
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Smoothing a rugged protein folding landscape by sequence-based redesign.
Sci Rep, 6, 2016
5CDX
DownloadVisualize
BU of 5cdx by Molmil
Crystal structure of conserpin
Descriptor: Conserpin
Authors:Porebski, B.T, Borg, N.A, McGowan, S, Buckle, A.M.
Deposit date:2015-07-06
Release date:2016-07-20
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Smoothing a rugged protein folding landscape by sequence-based redesign.
Sci Rep, 6, 2016
7SHW
DownloadVisualize
BU of 7shw by Molmil
Crystal structure of Mycobacterium smegmatis LmcA with xenon
Descriptor: GLYCEROL, LmcA, XENON
Authors:Patel, O, Lucet, I, Panjikar, S.
Deposit date:2021-10-11
Release date:2022-04-13
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Crystal structure of the putative cell-wall lipoglycan biosynthesis protein LmcA from Mycobacterium smegmatis.
Acta Crystallogr D Struct Biol, 78, 2022
5CEM
DownloadVisualize
BU of 5cem by Molmil
Pseudokinase and C-terminal extension of Human Tribbles Homolog 1
Descriptor: SULFATE ION, Tribbles homolog 1
Authors:Mace, P.D, Nakatani, Y.
Deposit date:2015-07-07
Release date:2015-11-11
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Molecular Mechanism of CCAAT-Enhancer Binding Protein Recruitment by the TRIB1 Pseudokinase.
Structure, 23, 2015
5CEK
DownloadVisualize
BU of 5cek by Molmil
Pseudokinase domain of Human Tribbles Homolog 1
Descriptor: Tribbles homolog 1
Authors:Mace, P.D, Nakatani, Y.
Deposit date:2015-07-07
Release date:2015-11-11
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Molecular Mechanism of CCAAT-Enhancer Binding Protein Recruitment by the TRIB1 Pseudokinase.
Structure, 23, 2015
8DGM
DownloadVisualize
BU of 8dgm by Molmil
14-3-3 epsilon bound to phosphorylated PEAK1 (pT1165) peptide
Descriptor: 1,2-ETHANEDIOL, 14-3-3 protein epsilon, Inactive tyrosine-protein kinase PEAK1
Authors:Roy, M.J, Hardy, J.M, Lucet, I.S.
Deposit date:2022-06-24
Release date:2023-06-07
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural mapping of PEAK pseudokinase interactions identifies 14-3-3 as a molecular switch for PEAK3 signaling.
Nat Commun, 14, 2023
8DGP
DownloadVisualize
BU of 8dgp by Molmil
14-3-3 epsilon bound to phosphorylated PEAK3 (pS69) peptide
Descriptor: 1,2-ETHANEDIOL, 14-3-3 protein epsilon, Phosphorylated PEAK3 (pS69) peptide, ...
Authors:Roy, M.J, Hardy, J.M, Lucet, I.S.
Deposit date:2022-06-24
Release date:2023-06-07
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural mapping of PEAK pseudokinase interactions identifies 14-3-3 as a molecular switch for PEAK3 signaling.
Nat Commun, 14, 2023
8DGN
DownloadVisualize
BU of 8dgn by Molmil
14-3-3 epsilon bound to phosphorylated PEAK2 (pS826) peptide
Descriptor: 14-3-3 protein epsilon, Phosphorylated PEAK2 (pS826) peptide
Authors:Roy, M.J, Hardy, J.M, Lucet, I.S.
Deposit date:2022-06-24
Release date:2023-06-07
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (3.16 Å)
Cite:Structural mapping of PEAK pseudokinase interactions identifies 14-3-3 as a molecular switch for PEAK3 signaling.
Nat Commun, 14, 2023
8DGO
DownloadVisualize
BU of 8dgo by Molmil
Growth Factor Receptor-Bound Protein 2 (Grb2) bound to phosphorylated PEAK3 (pY24) peptide
Descriptor: Growth factor receptor bound protein 2, Phosphorylated PEAK3 (pY24) peptide
Authors:Roy, M.J, Hardy, J.M, Lucet, I.S.
Deposit date:2022-06-24
Release date:2023-06-07
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural mapping of PEAK pseudokinase interactions identifies 14-3-3 as a molecular switch for PEAK3 signaling.
Nat Commun, 14, 2023
5G0Q
DownloadVisualize
BU of 5g0q by Molmil
beta-glucuronidase with an activity-based probe (N-alkyl cyclophellitol aziridine) bound
Descriptor: (1R,2S,3R,4S,5S,6R)-7-(8-AZIDOOCTYL)-3,4,5-TRIHYDROXY-, BETA-GLUCURONIDASE, GLYCEROL
Authors:Jin, Y, Wu, L, Jiang, J.B, Overkleeft, H.S, Davies, G.J.
Deposit date:2016-03-22
Release date:2017-04-12
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Activity-based probes for functional interrogation of retaining beta-glucuronidases.
Nat. Chem. Biol., 13, 2017
7KXW
DownloadVisualize
BU of 7kxw by Molmil
Crystal structure of DCLK1-KD in complex with DCLK1-IN-1
Descriptor: 2-{[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino}-11-methyl-5-(2,2,2-trifluoroethyl)-5,11-dihydro-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one, DI(HYDROXYETHYL)ETHER, Serine/threonine-protein kinase DCLK1, ...
Authors:Patel, O, Lucet, I.
Deposit date:2020-12-05
Release date:2021-09-22
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (3.002 Å)
Cite:Structural basis for small molecule targeting of Doublecortin Like Kinase 1 with DCLK1-IN-1.
Commun Biol, 4, 2021
7KX8
DownloadVisualize
BU of 7kx8 by Molmil
Crystal structure of DCLK1-Cter in complex with FMF-03-055-1
Descriptor: 5-ethyl-2-{[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino}-11-methyl-5,11-dihydro-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one, Serine/threonine-protein kinase DCLK1
Authors:Patel, O, Lucet, I.
Deposit date:2020-12-03
Release date:2021-09-22
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural basis for small molecule targeting of Doublecortin Like Kinase 1 with DCLK1-IN-1.
Commun Biol, 4, 2021
7KX6
DownloadVisualize
BU of 7kx6 by Molmil
Crystal structure of DCLK1-KD in complex with XMD8-85
Descriptor: 2-{[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino}-5,11-dimethyl-5,11-dihydro-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one, Serine/threonine-protein kinase DCLK1
Authors:Patel, O, Lucet, I.
Deposit date:2020-12-03
Release date:2021-09-22
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for small molecule targeting of Doublecortin Like Kinase 1 with DCLK1-IN-1.
Commun Biol, 4, 2021

 

12>

227111

数据于2024-11-06公开中

PDB statisticsPDBj update infoContact PDBjnumon