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7U6P
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BU of 7u6p by Molmil
Structure of an intellectual disability-associated ornithine decarboxylase variant G84R
Descriptor: Ornithine decarboxylase, PHOSPHATE ION
Authors:Zhou, X.E, Schultz, C.R, Powell, K.S, Henrickson, A, Lamp, J, Brunzelle, J.S, Demeler, B, Vega, I.E, Bachmann, A.S, Melcher, K.
Deposit date:2022-03-04
Release date:2022-10-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structure and Enzymatic Activity of an Intellectual Disability-Associated Ornithine Decarboxylase Variant, G84R.
Acs Omega, 7, 2022
7U6U
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BU of 7u6u by Molmil
Structure of an intellectual disability-associated ornithine decarboxylase variant G84R in complex with PLP
Descriptor: Ornithine decarboxylase, PYRIDOXAL-5'-PHOSPHATE
Authors:Zhou, X.E, Schultz, C.R, Powell, K.S, Henrickson, A, Lamp, J, Brunzelle, J.S, Demeler, B, Vega, I.E, Bachmann, A.S, Melcher, K.
Deposit date:2022-03-06
Release date:2022-10-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structure and Enzymatic Activity of an Intellectual Disability-Associated Ornithine Decarboxylase Variant, G84R.
Acs Omega, 7, 2022
7S3F
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BU of 7s3f by Molmil
Structure of cofactor pyridoxal 5-phosphate bound human ornithine decarboxylase in complex with its inhibitor 1-amino-oxy-3-aminopropane
Descriptor: 3-AMINOOXY-1-AMINOPROPANE, Ornithine decarboxylase, PYRIDOXAL-5'-PHOSPHATE
Authors:Zhou, X.E, Suino-Powell, K, Schultz, C.R, Aleiwi, B, Brunzelle, J.S, Lamp, J, Vega, I.E, Ellsworth, E, Bachmann, A.S, Melcher, K.
Deposit date:2021-09-06
Release date:2021-12-15
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Structural basis of binding and inhibition of ornithine decarboxylase by 1-amino-oxy-3-aminopropane.
Biochem.J., 478, 2021
7S3G
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BU of 7s3g by Molmil
Structure of cofactor pyridoxal 5-phosphate bound human ornithine decarboxylase in complex with citrate at the catalytic center
Descriptor: CITRIC ACID, Ornithine decarboxylase, PYRIDOXAL-5'-PHOSPHATE
Authors:Zhou, X.E, Suino-Powell, K, Schultz, C.R, Aleiwi, B, Brunzelle, J.S, Lamp, J, Vega, I.E, Ellsworth, E, Bachmann, A.S, Melcher, K.
Deposit date:2021-09-06
Release date:2021-12-15
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Structural basis of binding and inhibition of ornithine decarboxylase by 1-amino-oxy-3-aminopropane.
Biochem.J., 478, 2021
4GK7
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BU of 4gk7 by Molmil
yeast 20S proteasome in complex with the Syringolin-Glidobactin chimera
Descriptor: Proteasome component C1, Proteasome component C11, Proteasome component C5, ...
Authors:Groll, M, Stein, M.L, Bachmann, A.
Deposit date:2012-08-10
Release date:2012-08-29
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Activity enhancement of the synthetic syrbactin proteasome inhibitor hybrid and biological evaluation in tumor cells.
Biochemistry, 51, 2012
2ZCY
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BU of 2zcy by Molmil
yeast 20S proteasome:syringolin A-complex
Descriptor: (2S)-2-[[(2S)-1-[[(5S,8S,9E)-2,7-dioxo-5-propan-2-yl-1,6-diazacyclododeca-3,9-dien-8-yl]amino]-3-methyl-1-oxo-butan-2-yl]carbamoylamino]-3-methyl-butanoic acid, Proteasome component C1, Proteasome component C11, ...
Authors:Groll, M, Dudler, R, Kaiser, M.
Deposit date:2007-11-15
Release date:2008-04-08
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:A plant pathogen virulence factor inhibits the eukaryotic proteasome by a novel mechanism
Nature, 452, 2008
3BDM
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BU of 3bdm by Molmil
yeast 20S proteasome:glidobactin A-complex
Descriptor: (2E,4E)-N-[(2S,3R)-3-hydroxy-1-[[(3Z,5S,8S,10S)-10-hydroxy-5-methyl-2,7-dioxo-1,6-diazacyclododec-3-en-8-yl]amino]-1-ox obutan-2-yl]dodeca-2,4-dienamide, Proteasome component C1, Proteasome component C11, ...
Authors:Groll, M, Dudler, R, Kaiser, M.
Deposit date:2007-11-15
Release date:2008-04-08
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A plant pathogen virulence factor inhibits the eukaryotic proteasome by a novel mechanism
Nature, 452, 2008
3GPJ
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BU of 3gpj by Molmil
Crystal structure of the yeast 20S proteasome in complex with syringolin B
Descriptor: N-{[(1S)-2-methyl-1-{[(5S,8S)-5-(1-methylethyl)-2,7-dioxo-1,6-diazacyclododec-3-en-8-yl]carbamoyl}propyl]carbamoyl}-L-valine, Proteasome component C1, Proteasome component C11, ...
Authors:Groll, M, Huber, R, Kaiser, M.
Deposit date:2009-03-23
Release date:2009-06-02
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Synthetic and structural studies on syringolin A and B reveal critical determinants of selectivity and potency of proteasome inhibition
Proc.Natl.Acad.Sci.USA, 106, 2009

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数据于2024-10-30公开中

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