5Z8Z
| BRD4 Bromodomain 1 with an inhibitor | Descriptor: | 6-[(3S)-3-azanylpiperidin-1-yl]sulfonyl-1-ethyl-benzo[cd]indol-2-one, Bromodomain-containing protein 4 | Authors: | Xiao, S, Chen, S, Chen, H. | Deposit date: | 2018-02-01 | Release date: | 2019-02-06 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | BRD4 Bromodomain 1 with an inhibitor To Be Published
|
|
6KEE
| Crystal structure of BRD4 Bromodomain1 with an inhibitor | Descriptor: | 6-[2-[2,4-bis(fluoranyl)phenoxy]-5-(methylsulfonylmethyl)pyridin-3-yl]-8-methyl-2H-pyrrolo[1,2-a]pyrazin-1-one, Bromodomain-containing protein 4 | Authors: | Xiao, S, Li, Z, Chen, S, Zhou, B, Luo, C. | Deposit date: | 2019-07-04 | Release date: | 2020-07-08 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.12154651 Å) | Cite: | Crystal structure of BRD4 Bromodomain1 with an inhibitor To be published
|
|
6KEG
| BRD4 Bromodomain1 with an inhibitor | Descriptor: | 6-[2-[2,4-bis(fluoranyl)phenoxy]-5-(ethylsulfonylmethyl)pyridin-3-yl]-8-methyl-4H-pyrrolo[1,2-a]pyrazin-1-one, Bromodomain-containing protein 4 | Authors: | Xiao, S, Li, Z, Chen, S, Zhou, B, Luo, C. | Deposit date: | 2019-07-04 | Release date: | 2020-07-08 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.232 Å) | Cite: | BRD4 Bromodomain1 with an inhibitor To Be Published
|
|
6KEF
| BRD4 Bromodomain1 with an inhibitor | Descriptor: | Bromodomain-containing protein 4, N-[3-(8-methyl-1-oxidanylidene-2H-pyrrolo[1,2-a]pyrazin-6-yl)-4-phenoxy-phenyl]methanesulfonamide | Authors: | Xiao, S, Li, Z, Chen, S, Zhou, B, Luo, C. | Deposit date: | 2019-07-04 | Release date: | 2020-07-08 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.44467545 Å) | Cite: | BRD4 Bromodomain1 with an inhibitor To Be Published
|
|
6KED
| BRD4 Bromodomain1 with an inhibitor | Descriptor: | 6-[2-[2,4-bis(fluoranyl)phenoxy]-5-(methylsulfonylmethyl)pyridin-3-yl]-8-methyl-2H-pyrrolo[1,2-d][1,2,4]triazin-1-one, Bromodomain-containing protein 4 | Authors: | Xiao, S, Li, Z, Chen, S, Zhou, B, Luo, C. | Deposit date: | 2019-07-04 | Release date: | 2020-07-08 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.548447 Å) | Cite: | BRD4 Bromodomain1 with an inhibitor To Be Published
|
|
2LSW
| |
5Z90
| BRD4 Bromodomain 1 with an inhibitor | Descriptor: | 1-ethyl-6-pyrrolidin-1-ylsulfonyl-benzo[cd]indol-2-one, Bromodomain-containing protein 4 | Authors: | Xiao, S, Chen, S, Chen, H. | Deposit date: | 2018-02-01 | Release date: | 2019-02-06 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | BRD4 Bromodomain 1 with an inhibitor To Be Published
|
|
5Z8G
| BRD4 Bromodomain 1 with an inhibitor | Descriptor: | 1-ethyl-6-[(3R)-3-oxidanylpiperidin-1-yl]sulfonyl-benzo[cd]indol-2-one, Bromodomain-containing protein 4, DIMETHYL SULFOXIDE | Authors: | Xiao, S, Chen, S, Chen, H. | Deposit date: | 2018-01-31 | Release date: | 2019-02-06 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.701 Å) | Cite: | BRD4 Bromodomain 1 with an inhibitor To Be Published
|
|
5Z8R
| BRD4 Bromodomain 1 with an inhibitor | Descriptor: | 1-ethyl-6-[(3S)-3-oxidanylpiperidin-1-yl]sulfonyl-benzo[cd]indol-2-one, Bromodomain-containing protein 4 | Authors: | Xiao, S, Chen, S, Chen, H. | Deposit date: | 2018-02-01 | Release date: | 2019-02-06 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | BRD4 Bromodomain 1 with an inhibitor To Be Published
|
|
5Z9K
| BRD4 Bromodomain 1 with an inhibitor | Descriptor: | 1-ethyl-6-[(2R)-2-(hydroxymethyl)pyrrolidin-1-yl]sulfonyl-benzo[cd]indol-2-one, Bromodomain-containing protein 4 | Authors: | Xiao, S, Chen, S, Chen, H. | Deposit date: | 2018-02-03 | Release date: | 2019-02-06 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | BRD4 Bromodomain 1 with an inhibitor To Be Published
|
|
2N9D
| |
2N2N
| |
2N31
| |
5T7Q
| TIRAP phosphoinositide-binding motif | Descriptor: | Toll/interleukin-1 receptor domain-containing adapter protein | Authors: | Capelluto, D.G.S, Ellena, J.F, Armstrong, G, Zhao, X, Xiao, S. | Deposit date: | 2016-09-05 | Release date: | 2017-03-08 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Membrane targeting of TIRAP is negatively regulated by phosphorylation in its phosphoinositide-binding motif. Sci Rep, 7, 2017
|
|
4WZF
| Crystal structural basis for Rv0315, an immunostimulatory antigen and pseudo beta-1, 3-glucanase of Mycobacterium tuberculosis | Descriptor: | 1,2-ETHANEDIOL, 1,3-beta-glucanase, CALCIUM ION | Authors: | Dong, W.Y, Fu, Z.F, Peng, G.Q. | Deposit date: | 2014-11-19 | Release date: | 2015-12-09 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.699 Å) | Cite: | Crystal structural basis for Rv0315, an immunostimulatory antigen and inactive beta-1,3-glucanase of Mycobacterium tuberculosis. Sci Rep, 5, 2015
|
|
7YRV
| |
7YRW
| |
7YRX
| |
5HIY
| Crystal structure of PEDV NSP9 Mutant-C59A | Descriptor: | Non-structural protein 9 | Authors: | Deng, F, Peng, G. | Deposit date: | 2016-01-12 | Release date: | 2017-01-25 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Dimerization of Coronavirus nsp9 with Diverse Modes Enhances Its Nucleic Acid Binding Affinity. J.Virol., 92, 2018
|
|
5KWA
| |
5KZF
| |
4XFQ
| Crystal Structure Basis for PEDV 3C Like Protease | Descriptor: | PEDV main protease | Authors: | Ye, G, Fu, Z.F, Peng, G.Q. | Deposit date: | 2014-12-28 | Release date: | 2016-01-20 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structural basis for the dimerization and substrate recognition specificity of porcine epidemic diarrhea virus 3C-like protease. Virology, 494, 2016
|
|
4ZUH
| |
8SYC
| Crystal structure of PDE3B in complex with GSK4394835A | Descriptor: | MAGNESIUM ION, [3-[(4,7-dimethoxyquinolin-2-yl)carbonylamino]-5-[methyl-(phenylmethyl)carbamoyl]phenyl]-oxidanyl-oxidanylidene-boron, cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B | Authors: | Concha, N.O, Nolte, R. | Deposit date: | 2023-05-25 | Release date: | 2024-02-07 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Discovery and SAR Study of Boronic Acid-Based Selective PDE3B Inhibitors from a Novel DNA-Encoded Library. J.Med.Chem., 67, 2024
|
|
5HIZ
| The structure of PEDV NSP9 | Descriptor: | Non-structural protein 9 | Authors: | Deng, F, Peng, G. | Deposit date: | 2016-01-12 | Release date: | 2017-01-25 | Last modified: | 2019-07-03 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Dimerization of Coronavirus nsp9 with Diverse Modes Enhances Its Nucleic Acid Binding Affinity. J.Virol., 92, 2018
|
|