1VEU
| Crystal structure of the p14/MP1 complex at 2.15 A resolution | Descriptor: | Late endosomal/lysosomal Mp1 interacting protein, Mitogen-activated protein kinase kinase 1 interacting protein 1 | Authors: | Kurzbauer, R, Teis, D, Maurer-Stroh, S, Eisenhaber, F, Hekman, M, Bourenkov, G.P, Bartunik, H.D, Huber, L.A, Clausen, T. | Deposit date: | 2004-04-05 | Release date: | 2004-08-03 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Crystal structure of the p14/MP1 scaffolding complex: How a twin couple attaches mitogen- activated protein kinase signaling to late endosomes Proc.Natl.Acad.Sci.USA, 101, 2004
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1VET
| Crystal Structure of p14/MP1 at 1.9 A resolution | Descriptor: | Late endosomal/lysosomal Mp1 interacting protein, Mitogen-activated protein kinase kinase 1 interacting protein 1 | Authors: | Kurzbauer, R, Teis, D, Maurer-Stroh, S, Eisenhaber, F, Hekman, M, Bourenkov, G.P, Bartunik, H.D, Huber, L.A, Clausen, T. | Deposit date: | 2004-04-05 | Release date: | 2004-08-03 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of the p14/MP1 scaffolding complex: How a twin couple attaches mitogen- activated protein kinase signaling to late endosomes Proc.Natl.Acad.Sci.USA, 101, 2004
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1SOT
| Crystal Structure of the DegS stress sensor | Descriptor: | Protease degS | Authors: | Wilken, C, Kitzing, K, Kurzbauer, R, Ehrmann, M, Clausen, T. | Deposit date: | 2004-03-15 | Release date: | 2004-06-08 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of the DegS stress sensor: How a PDZ domain recognizes misfolded protein and activates a protease Cell(Cambridge,Mass.), 117, 2004
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2R3U
| Crystal structure of the PDZ deletion mutant of DegS | Descriptor: | Protease degS | Authors: | Clausen, T, Kurzbauer, R. | Deposit date: | 2007-08-30 | Release date: | 2007-11-27 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Regulation of the sigmaE stress response by DegS: how the PDZ domain keeps the protease inactive in the resting state and allows integration of different OMP-derived stress signals upon folding stress. Genes Dev., 21, 2007
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1SOZ
| Crystal Structure of DegS protease in complex with an activating peptide | Descriptor: | Protease degS, activating peptide | Authors: | Wilken, C, Kitzing, K, Kurzbauer, R, Ehrmann, M, Clausen, T. | Deposit date: | 2004-03-16 | Release date: | 2004-06-08 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of the DegS stress sensor: How a PDZ domain recognizes misfolded protein and activates a protease Cell(Cambridge,Mass.), 117, 2004
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1VCW
| Crystal structure of DegS after backsoaking the activating peptide | Descriptor: | Protease degS | Authors: | Wilken, C, Kitzing, K, Kurzbauer, R, Ehrmann, M, Clausen, T. | Deposit date: | 2004-03-16 | Release date: | 2004-06-08 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | Crystal structure of the DegS stress sensor: How a PDZ domain recognizes misfolded protein and activates a protease. Cell(Cambridge,Mass.), 117, 2004
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4C2C
| Crystal structure of the protease CtpB in an active state | Descriptor: | CARBOXY-TERMINAL PROCESSING PROTEASE CTPB, PEPTIDE1, PEPTIDE2 | Authors: | Mastny, M, Heuck, A, Kurzbauer, R, Clausen, T. | Deposit date: | 2013-08-17 | Release date: | 2013-12-04 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Ctpb Assembles a Gated Protease Tunnel Regulating Cell-Cell Signaling During Spore Formation in Bacillus Subtilis. Cell(Cambridge,Mass.), 155, 2013
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4C2E
| Crystal structure of the protease CtpB(S309A) present in a resting state | Descriptor: | CARBOXY-TERMINAL PROCESSING PROTEASE CTPB | Authors: | Mastny, M, Heuck, A, Kurzbauer, R, Clausen, T. | Deposit date: | 2013-08-17 | Release date: | 2013-12-04 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Ctpb Assembles a Gated Protease Tunnel Regulating Cell-Cell Signaling During Spore Formation in Bacillus Subtilis. Cell(Cambridge,Mass.), 155, 2013
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4C2D
| Crystal structure of the protease CtpB in an active state | Descriptor: | CARBOXY-TERMINAL PROCESSING PROTEASE CTPB, PEPTIDE1, PEPTIDE2 | Authors: | Mastny, M, Heuck, A, Kurzbauer, R, Clausen, T. | Deposit date: | 2013-08-17 | Release date: | 2013-12-04 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Ctpb Assembles a Gated Protease Tunnel Regulating Cell-Cell Signaling During Spore Formation in Bacillus Subtilis. Cell(Cambridge,Mass.), 155, 2013
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4C2G
| Crystal structure of CtpB(S309A) in complex with a peptide having a Val-Pro-Ala C-terminus | Descriptor: | CARBOXY-TERMINAL PROCESSING PROTEASE CTPB, PEPTIDE1 | Authors: | Mastny, M, Heuck, A, Kurzbauer, R, Clausen, T. | Deposit date: | 2013-08-17 | Release date: | 2013-12-04 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Ctpb Assembles a Gated Protease Tunnel Regulating Cell-Cell Signaling During Spore Formation in Bacillus Subtilis. Cell(Cambridge,Mass.), 155, 2013
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4C2H
| Crystal structure of the CtpB(V118Y) mutant | Descriptor: | CARBOXY-TERMINAL PROCESSING PROTEASE CTPB | Authors: | Mastny, M, Heuck, A, Kurzbauer, R, Clausen, T. | Deposit date: | 2013-08-17 | Release date: | 2013-12-04 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Ctpb Assembles a Gated Protease Tunnel Regulating Cell-Cell Signaling During Spore Formation in Bacillus Subtilis. Cell(Cambridge,Mass.), 155, 2013
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4C2F
| Crystal structure of the CtpB R168A mutant present in an active conformation | Descriptor: | CARBOXY-TERMINAL PROCESSING PROTEASE CTPB, PEPTIDE1, PEPTIDE2 | Authors: | Mastny, M, Heuck, A, Kurzbauer, R, Clausen, T. | Deposit date: | 2013-08-17 | Release date: | 2013-12-04 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Ctpb Assembles a Gated Protease Tunnel Regulating Cell-Cell Signaling During Spore Formation in Bacillus Subtilis. Cell(Cambridge,Mass.), 155, 2013
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7BII
| Crystal structure of Nematocida HUWE1 | Descriptor: | E3 ubiquitin-protein ligase HUWE1 | Authors: | Grabarczyk, D.B, Petrova, O.A, Meinhart, A, Kessler, D, Clausen, T. | Deposit date: | 2021-01-12 | Release date: | 2021-07-28 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (3.037 Å) | Cite: | HUWE1 employs a giant substrate-binding ring to feed and regulate its HECT E3 domain. Nat.Chem.Biol., 17, 2021
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6QDJ
| Molecular features of the UNC-45 chaperone critical for binding and folding muscle myosin | Descriptor: | 1,4-BUTANEDIOL, 2,5,8,11,14,17-HEXAOXANONADECAN-19-OL, ADENOSINE-5'-DIPHOSPHATE, ... | Authors: | Meinhart, A, Clausen, T, Arnese, R. | Deposit date: | 2019-01-02 | Release date: | 2019-10-30 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.884 Å) | Cite: | Molecular features of the UNC-45 chaperone critical for binding and folding muscle myosin. Nat Commun, 10, 2019
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6QDL
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6QDM
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6QDK
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6TV6
| Octameric McsB from Bacillus subtilis. | Descriptor: | MAGNESIUM ION, Protein-arginine kinase | Authors: | Suskiewicz, M.J, Hajdusits, B, Meinhart, A, Clausen, T. | Deposit date: | 2020-01-09 | Release date: | 2021-07-21 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | McsB forms a gated kinase chamber to mark aberrant bacterial proteins for degradation. Elife, 10, 2021
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5D4W
| Crystal structure of Hsp104 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Putative heat shock protein | Authors: | Heuck, A, Schitter-Sollner, S, Clausen, T. | Deposit date: | 2015-08-09 | Release date: | 2016-12-07 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (3.7 Å) | Cite: | Structural basis for the disaggregase activity and regulation of Hsp104. Elife, 5, 2016
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5HBN
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2R3Y
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8ATX
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8AUW
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8ATU
| Cryo-EM structure of human BIRC6 | Descriptor: | Baculoviral IAP repeat-containing protein 6, ZINC ION | Authors: | Ehrmann, J.F, Grabarczyk, D.B, Clausen, T. | Deposit date: | 2022-08-24 | Release date: | 2023-02-15 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structural basis for regulation of apoptosis and autophagy by the BIRC6/SMAC complex. Science, 379, 2023
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8AUK
| Cryo-EM structure of human BIRC6 in complex with HTRA2. | Descriptor: | Baculoviral IAP repeat-containing protein 6, Serine protease HTRA2, mitochondrial, ... | Authors: | Ehrmann, J.F, Grabarczyk, D.B, Clausen, T. | Deposit date: | 2022-08-25 | Release date: | 2023-02-15 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (6.2 Å) | Cite: | Structural basis for regulation of apoptosis and autophagy by the BIRC6/SMAC complex. Science, 379, 2023
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