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8KA8
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BU of 8ka8 by Molmil
Cryo-EM structure of SARS-CoV-2 Delta RBD in complex with golden hamster ACE2 (local refinement)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme, ...
Authors:Niu, S, Zhao, Z.N, Chai, Y, Gao, G.F.
Deposit date:2023-08-02
Release date:2024-01-31
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (2.96 Å)
Cite:Structural basis and analysis of hamster ACE2 binding to different SARS-CoV-2 spike RBDs.
J.Virol., 98, 2024
8KC2
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BU of 8kc2 by Molmil
Cryo-EM structure of SARS-CoV-2 BA.3 RBD in complex with golden hamster ACE2 (local refinement)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme, ...
Authors:Niu, S, Zhao, Z.N, Chai, Y, Gao, G.F.
Deposit date:2023-08-05
Release date:2024-01-31
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Structural basis and analysis of hamster ACE2 binding to different SARS-CoV-2 spike RBDs.
J.Virol., 98, 2024
6AEB
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BU of 6aeb by Molmil
Crystal structure of xCas9 in complex with sgRNA and target DNA (AAG PAM)
Descriptor: DNA (25-MER), DNA (5'-D(*AP*AP*AP*AP*AP*GP*TP*AP*TP*TP*G)-3'), DNA Nuclease, ...
Authors:Guo, M, Ren, K, Zhu, Y, Huang, Z.
Deposit date:2018-08-04
Release date:2019-03-27
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.004 Å)
Cite:Structural insights into a high fidelity variant of SpCas9.
Cell Res., 29, 2019
7K58
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BU of 7k58 by Molmil
Structure of outer-arm dyneins bound to microtubule with microtubule binding state 1(MTBS-1)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Dynein heavy chain, ...
Authors:Qinhui, R, Kai, Z.
Deposit date:2020-09-16
Release date:2021-09-29
Last modified:2021-10-20
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structures of outer-arm dynein array on microtubule doublet reveal a motor coordination mechanism.
Nat.Struct.Mol.Biol., 28, 2021
7K5B
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BU of 7k5b by Molmil
Structure of outer-arm dynein bound to microtubule doublet in microtubule binding state 2 (MTBS-2)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Dynein heavy chain, ...
Authors:Rao, Q, Zhang, K.
Deposit date:2020-09-16
Release date:2021-09-29
Last modified:2021-10-20
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Structures of outer-arm dynein array on microtubule doublet reveal a motor coordination mechanism.
Nat.Struct.Mol.Biol., 28, 2021
7EA7
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BU of 7ea7 by Molmil
crystal structure of NAP1 LIR in complex with GABARAP
Descriptor: Gamma-aminobutyric acid receptor-associated protein, NAP1_LIR motif
Authors:Fu, T, Pan, L.
Deposit date:2021-03-06
Release date:2021-12-22
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:Structural and biochemical advances on the recruitment of the autophagy-initiating ULK and TBK1 complexes by autophagy receptor NDP52.
Sci Adv, 7, 2021
7EA2
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BU of 7ea2 by Molmil
crystal structure of NAP1 FIR in complex with RB1CC1 Claw domain
Descriptor: 5-azacytidine-induced protein 2,RB1-inducible coiled-coil protein 1, CITRATE ANION, DI(HYDROXYETHYL)ETHER, ...
Authors:Fu, T, Pan, L.
Deposit date:2021-03-06
Release date:2021-12-22
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Structural and biochemical advances on the recruitment of the autophagy-initiating ULK and TBK1 complexes by autophagy receptor NDP52.
Sci Adv, 7, 2021
7EAA
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BU of 7eaa by Molmil
crystal structure of NDP52 SKICH domain in complex with RB1CC1 coiled-coil domain
Descriptor: Calcium-binding and coiled-coil domain-containing protein 2, RB1-inducible coiled-coil protein 1
Authors:Fu, T, Pan, L.
Deposit date:2021-03-06
Release date:2021-12-22
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural and biochemical advances on the recruitment of the autophagy-initiating ULK and TBK1 complexes by autophagy receptor NDP52.
Sci Adv, 7, 2021
7C3C
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BU of 7c3c by Molmil
Crystal structure of AofleA from Arthrobotrys oligospora in complex with D-manose
Descriptor: AofleA, GLYCEROL, alpha-D-mannopyranose, ...
Authors:Liu, M, Cheng, X, Wang, J, Zhang, M, Wang, M.
Deposit date:2020-05-12
Release date:2020-07-29
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.301 Å)
Cite:Structural insights into the fungi-nematodes interaction mediated by fucose-specific lectin AofleA from Arthrobotrys oligospora.
Int.J.Biol.Macromol., 164, 2020
7C37
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BU of 7c37 by Molmil
Crystal structure of AofleA from Arthrobotrys oligospora
Descriptor: AofleA, BICINE
Authors:Liu, M, Cheng, X, Wang, J, Zhang, M, Wang, M.
Deposit date:2020-05-11
Release date:2020-07-29
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.451 Å)
Cite:Structural insights into the fungi-nematodes interaction mediated by fucose-specific lectin AofleA from Arthrobotrys oligospora.
Int.J.Biol.Macromol., 164, 2020
7EY5
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BU of 7ey5 by Molmil
Local CryoEM structure of the SARS-CoV-2 S6PV2 in complex with BD-771 Fab and BD-821 Fab
Descriptor: BD-771H, BD-771L, BD-821H, ...
Authors:Zhang, Z.Y.
Deposit date:2021-05-29
Release date:2021-09-08
Last modified:2022-02-16
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structures of SARS-CoV-2 B.1.351 neutralizing antibodies provide insights into cocktail design against concerning variants.
Cell Res., 31, 2021
7EYA
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BU of 7eya by Molmil
Local CryoEM structure of the SARS-CoV-2 S6PV2 in complex with BD-804 Fab
Descriptor: BD-804H, BD-804L, Spike glycoprotein, ...
Authors:Du, S, Xiao, J.
Deposit date:2021-05-30
Release date:2021-09-08
Last modified:2022-02-16
Method:ELECTRON MICROSCOPY (3.77 Å)
Cite:Structures of SARS-CoV-2 B.1.351 neutralizing antibodies provide insights into cocktail design against concerning variants.
Cell Res., 31, 2021
7EY0
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BU of 7ey0 by Molmil
Local CryoEM structure of the SARS-CoV-2 S6PV2 in complex with BD-813 Fab and BD-744 Fab
Descriptor: BD-744H, BD-744L, BD-813H, ...
Authors:Du, S, Xiao, J.
Deposit date:2021-05-29
Release date:2021-09-08
Last modified:2022-02-16
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structures of SARS-CoV-2 B.1.351 neutralizing antibodies provide insights into cocktail design against concerning variants.
Cell Res., 31, 2021
7EZV
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BU of 7ezv by Molmil
local CryoEM structure of the SARS-CoV-2 S6PV2 in complex with BD-812 Fab and BD-836 Fab
Descriptor: 812 H, 812L, 836H, ...
Authors:Liu, P.L.
Deposit date:2021-06-02
Release date:2021-09-08
Last modified:2022-02-16
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structures of SARS-CoV-2 B.1.351 neutralizing antibodies provide insights into cocktail design against concerning variants.
Cell Res., 31, 2021
7EY4
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BU of 7ey4 by Molmil
Local CryoEM of the SARS-CoV-2 S6PV2 in complex with BD-667
Descriptor: BD-667 H, BD-667 L, Spike glycoprotein, ...
Authors:Liu, P.L.
Deposit date:2021-05-29
Release date:2021-09-08
Last modified:2022-02-16
Method:ELECTRON MICROSCOPY (3.69 Å)
Cite:Structures of SARS-CoV-2 B.1.351 neutralizing antibodies provide insights into cocktail design against concerning variants.
Cell Res., 31, 2021
7JUP
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BU of 7jup by Molmil
Structure of human TRPA1 in complex with antagonist compound 21
Descriptor: 1-({3-[(3R,5R)-5-(4-fluorophenyl)oxolan-3-yl]-1,2,4-oxadiazol-5-yl}methyl)-7-methyl-1,7-dihydro-6H-purin-6-one, Transient receptor potential cation channel subfamily A member 1
Authors:Rohou, A, Rouge, L.
Deposit date:2020-08-20
Release date:2021-03-31
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.05 Å)
Cite:Tetrahydrofuran-Based Transient Receptor Potential Ankyrin 1 (TRPA1) Antagonists: Ligand-Based Discovery, Activity in a Rodent Asthma Model, and Mechanism-of-Action via Cryogenic Electron Microscopy.
J.Med.Chem., 64, 2021
4MJR
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BU of 4mjr by Molmil
E. coli sliding clamp in complex with (S)-Carprofen
Descriptor: (2S)-2-(6-chloro-9H-carbazol-2-yl)propanoic acid, CALCIUM ION, CHLORIDE ION, ...
Authors:Yin, Z, Oakley, A.J.
Deposit date:2013-09-04
Release date:2013-09-18
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:DNA replication is the target for the antibacterial effects of nonsteroidal anti-inflammatory drugs.
Chem.Biol., 21, 2014
4MJP
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BU of 4mjp by Molmil
E. coli sliding clamp in complex with (R)-Vedaprofen
Descriptor: (2R)-2-(4-cyclohexylnaphthalen-1-yl)propanoic acid, CALCIUM ION, CHLORIDE ION, ...
Authors:Yin, Z, Oakley, A.J.
Deposit date:2013-09-04
Release date:2013-09-18
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.855 Å)
Cite:DNA replication is the target for the antibacterial effects of nonsteroidal anti-inflammatory drugs.
Chem.Biol., 21, 2014
4OVF
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BU of 4ovf by Molmil
E. coli sliding clamp in complex with (R)-6-chloro-2,3,4,9-tetrahydro-1H-carbazole-2-carboxylic acid
Descriptor: (2R)-6-chloro-2,3,4,9-tetrahydro-1H-carbazole-2-carboxylic acid, CALCIUM ION, CHLORIDE ION, ...
Authors:Yin, Z, Oakley, A.J.
Deposit date:2014-02-21
Release date:2014-03-05
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Bacterial Sliding Clamp Inhibitors that Mimic the Sequential Binding Mechanism of Endogenous Linear Motifs.
J.Med.Chem., 58, 2015
8WP0
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BU of 8wp0 by Molmil
Structure of the Arabidopsis E529Q/E1174Q ABCB19 in the ATP bound state
Descriptor: ABC transporter B family member 19, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION
Authors:Ying, W, Wei, H, Liu, X, Sun, L.
Deposit date:2023-10-08
Release date:2024-03-13
Last modified:2024-04-03
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure and function of the Arabidopsis ABC transporter ABCB19 in brassinosteroid export.
Science, 383, 2024
8WOI
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BU of 8woi by Molmil
Structure of the wild-type Arabidopsis ABCB19 in the apo state
Descriptor: ABC transporter B family member 19
Authors:Ying, W, Wei, H, Liu, X, Sun, L.
Deposit date:2023-10-07
Release date:2024-03-13
Last modified:2024-04-03
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure and function of the Arabidopsis ABC transporter ABCB19 in brassinosteroid export.
Science, 383, 2024
8WOM
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BU of 8wom by Molmil
Structure of the wild-type Arabidopsis ABCB19 in the brassinolide-bound state
Descriptor: ABC transporter B family member 19, Brassinolide
Authors:Ying, W, Wei, H, Liu, X, Sun, L.
Deposit date:2023-10-07
Release date:2024-03-13
Last modified:2024-04-03
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structure and function of the Arabidopsis ABC transporter ABCB19 in brassinosteroid export.
Science, 383, 2024
8WOO
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BU of 8woo by Molmil
Structure of the wild-type Arabidopsis ABCB19 in the brassinolide and AMP-PNP bound state
Descriptor: ABC transporter B family member 19, Brassinolide, MAGNESIUM ION, ...
Authors:Ying, W, Wei, H, Liu, X, Sun, L.
Deposit date:2023-10-07
Release date:2024-03-13
Last modified:2024-04-03
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structure and function of the Arabidopsis ABC transporter ABCB19 in brassinosteroid export.
Science, 383, 2024
4P4R
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BU of 4p4r by Molmil
Structural Basis of Chronic Beryllium Disease: Bridging the Gap Between Allergic Hypersensitivity and Autoimmunity
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II histocompatibility antigen, DP alpha 1 chain, ...
Authors:Clayton, G.M, Crawford, F, Kappler, J.W.
Deposit date:2014-03-13
Release date:2014-07-16
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis of chronic beryllium disease: linking allergic hypersensitivity and autoimmunity.
Cell, 158, 2014
4P61
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BU of 4p61 by Molmil
CHICKEN TRIOSEPHOSPHATE ISOMERASE WITH LOOP6 MUTATIONS, V167P AND W168E.
Descriptor: Triosephosphate isomerase
Authors:Pegan, S.D, Mesecar, A.D.
Deposit date:2014-03-21
Release date:2014-08-27
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.34 Å)
Cite:Enzyme architecture: the effect of replacement and deletion mutations of loop 6 on catalysis by triosephosphate isomerase.
Biochemistry, 53, 2014

226414

数据于2024-10-23公开中

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