6U7E
 
 | | HCoV-229E RBD Class III in complex with human APN | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Aminopeptidase N, ... | | Authors: | Tomlinson, A.C.A, Li, Z, Rini, J.M. | | Deposit date: | 2019-09-02 | | Release date: | 2019-11-13 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | The human coronavirus HCoV-229E S-protein structure and receptor binding.
Elife, 8, 2019
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6U7G
 | | HCoV-229E RBD Class V in complex with human APN | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Aminopeptidase N, ... | | Authors: | Tomlinson, A, Li, Z, Rini, J.M. | | Deposit date: | 2019-09-02 | | Release date: | 2019-11-13 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | The human coronavirus HCoV-229E S-protein structure and receptor binding.
Elife, 8, 2019
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6U7F
 | | HCoV-229E RBD Class IV in complex with human APN | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Aminopeptidase N, ... | | Authors: | Tomlinson, A.C.A, Li, Z, Rini, J.M. | | Deposit date: | 2019-09-02 | | Release date: | 2019-11-13 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | The human coronavirus HCoV-229E S-protein structure and receptor binding.
Elife, 8, 2019
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4JEK
 | | Structure of dibenzothiophene monooxygenase (DszC) from Rhodococcus erythropolis | | Descriptor: | Dibenzothiophene desulfurization enzyme C | | Authors: | Zhang, L, Duan, X.L, Zhou, D.M, Li, X. | | Deposit date: | 2013-02-27 | | Release date: | 2013-09-18 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystallization and preliminary structural analysis of dibenzothiophene monooxygenase (DszC) from Rhodococcus erythropolis
Acta Crystallogr.,Sect.F, 69, 2013
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4FYQ
 | | Human aminopeptidase N (CD13) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETIC ACID, ... | | Authors: | Wong, A.H, Rini, J.M. | | Deposit date: | 2012-07-05 | | Release date: | 2012-09-05 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | The X-ray Crystal Structure of Human Aminopeptidase N Reveals a Novel Dimer and the Basis for Peptide Processing.
J.Biol.Chem., 287, 2012
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6A82
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6ATK
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4PGO
 | | Crystal structure of hypothetical protein PF0907 from Pyrococcus furiosus solved by sulfur SAD using Swiss Light Source data | | Descriptor: | CHLORIDE ION, Uncharacterized protein | | Authors: | Weinert, T, Waltersperger, S, Olieric, V, Panepucci, E, Chen, L, Rose, J.P, Wang, M, Wang, B.C, Southeast Collaboratory for Structural Genomics (SECSG) | | Deposit date: | 2014-05-02 | | Release date: | 2014-12-10 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Fast native-SAD phasing for routine macromolecular structure determination.
Nat.Methods, 12, 2015
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4PII
 | | Crystal structure of hypothetical protein PF0907 from pyrococcus furiosus solved by sulfur SAD using Swiss light source data | | Descriptor: | CHLORIDE ION, IMIDAZOLE, N-glycosylase/DNA lyase | | Authors: | Weinert, T, Waltersperger, S, Olieric, V, Panepucci, E, Chen, L, Rose, J.P, Wang, M, Wang, B.C, Southeast Collaboratory for Structural Genomics (SECSG) | | Deposit date: | 2014-05-08 | | Release date: | 2014-12-10 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.17 Å) | | Cite: | Fast native-SAD phasing for routine macromolecular structure determination.
Nat.Methods, 12, 2015
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4R8U
 | | S-SAD structure of DINB-DNA Complex | | Descriptor: | 5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]thymidine, DNA, DNA polymerase IV, ... | | Authors: | Kottur, J, Nair, D.T, Weinert, T, Oligeric, V, Wang, M. | | Deposit date: | 2014-09-03 | | Release date: | 2015-01-14 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Fast native-SAD phasing for routine macromolecular structure determination
Nat.Methods, 12, 2015
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4R8T
 | | Structure of JEV protease | | Descriptor: | CHLORIDE ION, NS3, Serine protease subunit NS2B | | Authors: | Nair, D.T, Weinert, T, Wang, M, Olieric, V. | | Deposit date: | 2014-09-03 | | Release date: | 2014-12-24 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.133 Å) | | Cite: | Fast native-SAD phasing for routine macromolecular structure determination.
Nat.Methods, 12, 2015
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5DH3
 | | Crystal structure of MST2 in complex with XMU-MP-1 | | Descriptor: | 4-[(5,10-dimethyl-6-oxo-6,10-dihydro-5H-pyrimido[5,4-b]thieno[3,2-e][1,4]diazepin-2-yl)amino]benzenesulfonamide, CHLORIDE ION, SULFATE ION, ... | | Authors: | Kong, L.L, Yun, C.H. | | Deposit date: | 2015-08-29 | | Release date: | 2016-08-31 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.468 Å) | | Cite: | Pharmacological targeting of kinases MST1 and MST2 augments tissue repair and regeneration
Sci Transl Med, 8, 2016
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8QTD
 | | Local refinement of SARS-CoV-2 BA.2.86 Spike and XBB-7 Fab | | Descriptor: | Spike glycoprotein,Fibritin, XBB-7 fab heavy chain, XBB-7 fab light chain | | Authors: | Ren, J, Duyvesteyn, H.M.E, Stuart, D.I. | | Deposit date: | 2023-10-12 | | Release date: | 2024-05-08 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | A structure-function analysis shows SARS-CoV-2 BA.2.86 balances antibody escape and ACE2 affinity.
Cell Rep Med, 5, 2024
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8R8K
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8TB0
 | | Cryo-EM Structure of GPR61-G protein complex stabilized by scFv16 | | Descriptor: | GPR61 fused to dominant negative G alpha S/I N18 chimera, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | Authors: | Lees, J.A, Dias, J.M, Han, S. | | Deposit date: | 2023-06-28 | | Release date: | 2023-10-04 | | Method: | ELECTRON MICROSCOPY (3.47 Å) | | Cite: | An inverse agonist of orphan receptor GPR61 acts by a G protein-competitive allosteric mechanism.
Nat Commun, 14, 2023
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8TB7
 | | Cryo-EM Structure of GPR61- | | Descriptor: | 6-{[(3,5-difluoropyridin-4-yl)methyl]amino}-N-(4-ethoxy-6-methylpyrimidin-2-yl)-2-methoxy-N-(2-methoxyethyl)pyridine-3-sulfonamide, Fab hinge-binding nanobody, Fab24 BAK5 heavy chain, ... | | Authors: | Lees, J.A, Dias, J.M, Han, S. | | Deposit date: | 2023-06-28 | | Release date: | 2023-10-04 | | Method: | ELECTRON MICROSCOPY (2.94 Å) | | Cite: | An inverse agonist of orphan receptor GPR61 acts by a G protein-competitive allosteric mechanism.
Nat Commun, 14, 2023
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8HII
 | | The BRIL-SLC19A1/Fab/Nb ternary complex | | Descriptor: | BRIL-SLC19A1 chimera, anti-BRIL Fab heavy chain, anti-BRIL Fab light chain, ... | | Authors: | Zhang, Z, Dang, Y. | | Deposit date: | 2022-11-20 | | Release date: | 2022-12-21 | | Last modified: | 2023-01-11 | | Method: | ELECTRON MICROSCOPY (3.57 Å) | | Cite: | Molecular mechanism of substrate recognition by folate transporter SLC19A1.
Cell Discov, 8, 2022
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8HIK
 | | The TPP-bound BRIL-SLC19A1/Fab/Nb ternary complex | | Descriptor: | Anti-BRIL Fab heavy chain, Anti-BRIL Fab light chain, Anti-Fab nanobody, ... | | Authors: | Zhang, Z, Dang, Y. | | Deposit date: | 2022-11-20 | | Release date: | 2022-12-21 | | Last modified: | 2023-01-11 | | Method: | ELECTRON MICROSCOPY (3.72 Å) | | Cite: | Molecular mechanism of substrate recognition by folate transporter SLC19A1.
Cell Discov, 8, 2022
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8HIJ
 | | The 5-MTHF-bound BRIL-SLC19A1/Fab/Nb ternary complex | | Descriptor: | Anti-BRIL Fab heavy chain, Anti-BRIL Fab light chain, Anti-Fab nanobody, ... | | Authors: | Zhang, Z, Dang, Y. | | Deposit date: | 2022-11-20 | | Release date: | 2022-12-21 | | Last modified: | 2023-01-11 | | Method: | ELECTRON MICROSCOPY (3.54 Å) | | Cite: | Molecular mechanism of substrate recognition by folate transporter SLC19A1.
Cell Discov, 8, 2022
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8HXA
 | | Cryo-EM structure of MPXV M2 in complex with human B7.1 | | Descriptor: | NFkB inhibitor, T-lymphocyte activation antigen CD80 | | Authors: | Wang, Y, Yang, S, Zhao, H, Deng, Z. | | Deposit date: | 2023-01-04 | | Release date: | 2023-08-30 | | Last modified: | 2023-12-13 | | Method: | ELECTRON MICROSCOPY (3.04 Å) | | Cite: | Structural and functional insights into the modulation of T cell costimulation by monkeypox virus protein M2.
Nat Commun, 14, 2023
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8HXC
 | | Cryo-EM structure of MPXV M2 heptamer in complex with human B7.2 | | Descriptor: | NFkB inhibitor, T-lymphocyte activation antigen CD86 | | Authors: | Wang, Y, Yang, S, Zhao, H, Deng, Z. | | Deposit date: | 2023-01-04 | | Release date: | 2023-08-30 | | Last modified: | 2023-12-13 | | Method: | ELECTRON MICROSCOPY (3.12 Å) | | Cite: | Structural and functional insights into the modulation of T cell costimulation by monkeypox virus protein M2.
Nat Commun, 14, 2023
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8HXB
 | | Cryo-EM structure of MPXV M2 hexamer in complex with human B7.2 | | Descriptor: | NFkB inhibitor, T-lymphocyte activation antigen CD86 | | Authors: | Wang, Y, Yang, S, Zhao, H, Deng, Z. | | Deposit date: | 2023-01-04 | | Release date: | 2023-08-30 | | Last modified: | 2023-12-13 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Structural and functional insights into the modulation of T cell costimulation by monkeypox virus protein M2.
Nat Commun, 14, 2023
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5UB5
 | | human POGLUT1 in complex with human Notch1 EGF12 S458T mutant and UDP | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Neurogenic locus notch homolog protein 1, ... | | Authors: | Li, Z, Rini, J.M. | | Deposit date: | 2016-12-20 | | Release date: | 2017-08-09 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.089 Å) | | Cite: | Structural basis of Notch O-glucosylation and O-xylosylation by mammalian protein-O-glucosyltransferase 1 (POGLUT1).
Nat Commun, 8, 2017
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5ZVV
 | | Structure of SeMet-phAimR | | Descriptor: | AimR transcriptional regulator, GLYCEROL | | Authors: | Cheng, W, Dou, C. | | Deposit date: | 2018-05-13 | | Release date: | 2018-09-05 | | Last modified: | 2019-03-13 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural and functional insights into the regulation of the lysis-lysogeny decision in viral communities.
Nat Microbiol, 3, 2018
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5ZZU
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