7A9D
| Crystal structure of H12 Haemagglutinin | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin | Authors: | Xiong, X, Walker, P, Zhang, J, Gamblin, S, Skehel, J.J. | Deposit date: | 2020-09-01 | Release date: | 2020-12-02 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Hemagglutinin Structure and Activities. Cold Spring Harb Perspect Med, 11, 2021
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1ALD
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7ZJ6
| X-31 Hemagglutinin Precursor HA0 at pH 7.5 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin,Fibritin, ... | Authors: | Garcia-Moro, E, Rosenthal, P.B. | Deposit date: | 2022-04-08 | Release date: | 2022-08-17 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Reversible structural changes in the influenza hemagglutinin precursor at membrane fusion pH. Proc.Natl.Acad.Sci.USA, 119, 2022
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2ALD
| HUMAN MUSCLE ALDOLASE | Descriptor: | FRUCTOSE-BISPHOSPHATE ALDOLASE | Authors: | Dalby, A.R, Littlechild, J.A. | Deposit date: | 1998-10-21 | Release date: | 1999-04-20 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of human muscle aldolase complexed with fructose 1,6-bisphosphate: mechanistic implications. Protein Sci., 8, 1999
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5M5G
| Crystal structure of the Chaetomium Thermophilum polycomb repressive complex 2 (PRC2) | Descriptor: | Fragment from molecular 2 (region containing putative polycomb protein Suz12), HISTONE H3 11-Mer peptide, Putative uncharacterized protein, ... | Authors: | Zhang, Y, Justin, N, Wilson, J, Gamblin, S. | Deposit date: | 2016-10-21 | Release date: | 2017-01-11 | Last modified: | 2019-10-16 | Method: | X-RAY DIFFRACTION (2.27 Å) | Cite: | Comment on "Structural basis of histone H3K27 trimethylation by an active polycomb repressive complex 2". Science, 354, 2016
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5LS6
| Structure of Human Polycomb Repressive Complex 2 (PRC2) with inhibitor | Descriptor: | 1-[(1~{R})-1-[1-[2,2-bis(fluoranyl)propyl]piperidin-4-yl]ethyl]-~{N}-[(4-methoxy-6-methyl-2-oxidanylidene-3~{H}-pyridin-3-yl)methyl]-2-methyl-indole-3-carboxamide, Histone-lysine N-methyltransferase EZH2,Histone-lysine N-methyltransferase EZH2,Histone-lysine N-methyltransferase EZH2, Jarid2 K116me3, ... | Authors: | Zhang, Y, Justin, N, Chen, S, Wilson, J, Gamblin, S. | Deposit date: | 2016-08-22 | Release date: | 2017-02-22 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3.47 Å) | Cite: | Identification of (R)-N-((4-Methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-2-methyl-1-(1-(1-(2,2,2-trifluoroethyl)piperidin-4-yl)ethyl)-1H-indole-3-carboxamide (CPI-1205), a Potent and Selective Inhibitor of Histone Methyltransferase EZH2, Suitable for Phase I Clinical Trials for B-Cell Lymphomas. J. Med. Chem., 59, 2016
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1SIE
| MURINE POLYOMAVIRUS COMPLEXED WITH A DISIALYLATED OLIGOSACCHARIDE | Descriptor: | N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-[N-acetyl-alpha-neuraminic acid-(2-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, POLYOMAVIRUS COAT PROTEIN VP1 | Authors: | Stehle, T, Harrison, S.C. | Deposit date: | 1995-12-12 | Release date: | 1996-06-20 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.65 Å) | Cite: | Crystal structures of murine polyomavirus in complex with straight-chain and branched-chain sialyloligosaccharide receptor fragments. Structure, 4, 1996
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1SID
| MURINE POLYOMAVIRUS COMPLEXED WITH 3'SIALYL LACTOSE | Descriptor: | N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, POLYOMAVIRUS COAT PROTEIN VP1 | Authors: | Stehle, T, Harrison, S.C. | Deposit date: | 1995-12-12 | Release date: | 1996-06-20 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.65 Å) | Cite: | Crystal structures of murine polyomavirus in complex with straight-chain and branched-chain sialyloligosaccharide receptor fragments. Structure, 4, 1996
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1PHP
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6HJR
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6HKG
| Structure of FISW84 Fab Fragment | Descriptor: | FISW84 Fab Fragment Heavy Chain, FISW84 Fab Fragment Light Chain, SULFATE ION | Authors: | Benton, D.J, Rosenthal, P.B. | Deposit date: | 2018-09-06 | Release date: | 2018-09-26 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | Influenza hemagglutinin membrane anchor. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6HJN
| Structure of Influenza Hemagglutinin ectodomain (A/duck/Alberta/35/76) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... | Authors: | Benton, D.J, Rosenthal, P.B. | Deposit date: | 2018-09-04 | Release date: | 2018-09-26 | Last modified: | 2024-10-16 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Influenza hemagglutinin membrane anchor. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6HJP
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6HJQ
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6Y5K
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6Y5H
| Ectodomain of X-31 Haemagglutinin at pH 5 (State I) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, X-31 Influenza Haemagglutinin HA1, ... | Authors: | Benton, D.J, Rosenthal, P.B. | Deposit date: | 2020-02-25 | Release date: | 2020-06-10 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural transitions in influenza haemagglutinin at membrane fusion pH. Nature, 583, 2020
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6Y5I
| Dilated form 1 of X-31 Influenza Haemagglutinin at pH 5 (State II) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, X-31 Influenza Haemagglutinin HA1, ... | Authors: | Benton, D.J, Rosenthal, P.B. | Deposit date: | 2020-02-25 | Release date: | 2020-06-10 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (5.5 Å) | Cite: | Structural transitions in influenza haemagglutinin at membrane fusion pH. Nature, 583, 2020
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6Y5G
| Ectodomain of X-31 Haemagglutinin at pH 8 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, X-31 Influenza Haemagglutinin HA1, ... | Authors: | Benton, D.J, Rosenthal, P.B. | Deposit date: | 2020-02-25 | Release date: | 2020-06-10 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural transitions in influenza haemagglutinin at membrane fusion pH. Nature, 583, 2020
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6Y5L
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6Y5J
| Dilated form 2 of X-31 Influenza Haemagglutinin at pH 5 (State III) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, X-31 Influenza Haemagglutinin HA1, ... | Authors: | Benton, D.J, Rosenthal, P.B. | Deposit date: | 2020-02-25 | Release date: | 2020-06-10 | Last modified: | 2024-10-16 | Method: | ELECTRON MICROSCOPY (5.6 Å) | Cite: | Structural transitions in influenza haemagglutinin at membrane fusion pH. Nature, 583, 2020
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6TJY
| Crystal structure of haemagglutinin from (A/seal/Germany/1/2014) seal H10N7 influenza virus | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Zhang, J, Xiong, X, Purkiss, A, Walker, P, Gamblin, S, Skehel, J.J. | Deposit date: | 2019-11-27 | Release date: | 2020-10-21 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (2.82 Å) | Cite: | Hemagglutinin Traits Determine Transmission of Avian A/H10N7 Influenza Virus between Mammals. Cell Host Microbe, 28, 2020
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6TJW
| Crystal structure of the haemagglutinin mutant (Gln226Leu, Del228) from an H10N7 seal influenza virus isolated in Germany | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Zhang, J, Xiong, X, Purkiss, A, Walker, P, Gamblin, S, Skehel, J.J. | Deposit date: | 2019-11-27 | Release date: | 2020-10-21 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.31 Å) | Cite: | Hemagglutinin Traits Determine Transmission of Avian A/H10N7 Influenza Virus between Mammals. Cell Host Microbe, 28, 2020
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6TY1
| Crystal structure of the haemagglutinin mutant (Gln226Leu, Gly228Ser) from an H10N7 seal influenza virus isolated in Germany in complex with human receptor analogue 6'-SLN | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, Hemagglutinin HA2, ... | Authors: | Zhang, J, Xiong, X, Purkiss, A, Walker, P, Gamblin, S, Skehel, J.J. | Deposit date: | 2020-01-15 | Release date: | 2020-10-21 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Hemagglutinin Traits Determine Transmission of Avian A/H10N7 Influenza Virus between Mammals. Cell Host Microbe, 28, 2020
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6TVA
| Crystal structure of the haemagglutinin from a transmissible H10N7 seal influenza virus isolated in Netherland in complex with avian receptor analogue, 3'-SLN | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Haemagglutinin HA1, Haemagglutinin HA2, ... | Authors: | Zhang, J, Xiong, X, Purkiss, A, Walker, P, Gamblin, S, Skehel, J.J. | Deposit date: | 2020-01-09 | Release date: | 2020-10-21 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | Hemagglutinin Traits Determine Transmission of Avian A/H10N7 Influenza Virus between Mammals. Cell Host Microbe, 28, 2020
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6TVR
| Crystal structure of the haemagglutinin mutant (Gln226Leu) from an H10N7 seal influenza virus isolated in Germany | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Zhang, J, Xiong, X, Purkiss, A, Walker, P, Gamblin, S, Skehel, J.J. | Deposit date: | 2020-01-10 | Release date: | 2020-10-21 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.63 Å) | Cite: | Hemagglutinin Traits Determine Transmission of Avian A/H10N7 Influenza Virus between Mammals. Cell Host Microbe, 28, 2020
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