6BCI
 
 | | Wild-type I-LtrI bound to non-cognate C4 substrate (pre-cleavage complex) | | Descriptor: | CALCIUM ION, DNA (27-MER), Ribosomal protein 3/homing endonuclease-like fusion protein | | Authors: | Brown, C, Zhang, K, McMurrough, T.A, Gloor, G.B, Edgell, D.R, Junop, M. | | Deposit date: | 2017-10-20 | | Release date: | 2018-10-24 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.28 Å) | | Cite: | Active site residue identity regulates cleavage preference of LAGLIDADG homing endonucleases.
Nucleic Acids Res., 46, 2018
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6BDG
 | | HFQ monomer in spacegroup p6 at 1.93 angstrom resolution | | Descriptor: | RNA-binding protein Hfq | | Authors: | Brown, C, Zhang, K, Seo, C, Ellis, M.J, Hanniford, D.B, Junop, M. | | Deposit date: | 2017-10-23 | | Release date: | 2017-11-01 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.964 Å) | | Cite: | HFQ monomer in spacegroup p6 at 1.93 angstrom resolution
To Be Published
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5EWP
 | | ARO (armadillo repeats only protein) from Plasmodium falciparum | | Descriptor: | ARO (armadillo repeats only protein) | | Authors: | Brown, C, Zhang, K, Emery, J, Prusty, D, Wetzel, J, Heincke, D, Gilberger, T, Junop, M. | | Deposit date: | 2015-11-20 | | Release date: | 2016-01-27 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | ARO (armadillo repeats only protein) from Plasmodium falciparum
To Be Published
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5HSI
 | | Crystal structure of tyrosine decarboxylase at 1.73 Angstroms resolution | | Descriptor: | MAGNESIUM ION, Putative decarboxylase | | Authors: | Ni, Y, Zhou, J, Zhu, H, Zhang, K. | | Deposit date: | 2016-01-25 | | Release date: | 2016-09-21 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.732 Å) | | Cite: | Crystal structure of tyrosine decarboxylase and identification of key residues involved in conformational swing and substrate binding
Sci Rep, 6, 2016
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5HSJ
 | | Structure of tyrosine decarboxylase complex with PLP at 1.9 Angstroms resolution | | Descriptor: | PYRIDOXAL-5'-PHOSPHATE, Putative decarboxylase | | Authors: | Ni, Y, Zhou, J, Zhu, H, Zhang, K. | | Deposit date: | 2016-01-25 | | Release date: | 2016-09-14 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal structure of tyrosine decarboxylase and identification of key residues involved in conformational swing and substrate binding
Sci Rep, 6, 2016
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6LS4
 | | A novel anti-tumor agent S-40 in complex with tubulin | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 3-[(4-cyclopropylphenyl)sulfonylamino]-4-methyl-N-(pyridin-3-ylmethyl)benzamide, GLYCEROL, ... | | Authors: | Du, T, Lin, S, Ji, M, Xue, N, Liu, Y, Zhang, K, Lu, D, Chen, X, Xu, H. | | Deposit date: | 2020-01-17 | | Release date: | 2021-01-20 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | A novel orally active microtubule destabilizing agent S-40 targets the colchicine-binding site and shows potent antitumor activity.
Cancer Lett., 495, 2020
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4MBQ
 | | TPR3 of FimV from P. aeruginosa (PAO1) | | Descriptor: | Motility protein FimV | | Authors: | Nguyen, Y, Zhang, K, Daniel-Ivad, M, Robinson, H, Wolfram, F, Sugiman-Marangos, S.N, Junop, M.S, Burrows, L.L, Howell, P.L. | | Deposit date: | 2013-08-19 | | Release date: | 2014-08-20 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.006 Å) | | Cite: | Crystal structure of TPR2 from FimV
To be Published
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3T9K
 | | Crystal Structure of ACAP1 C-portion mutant S554D fused with integrin beta1 peptide | | Descriptor: | Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1,Peptide from Integrin beta-1, SULFATE ION, ... | | Authors: | Sun, F, Pang, X, Zhang, K, Ma, J, Zhou, Q. | | Deposit date: | 2011-08-03 | | Release date: | 2012-07-18 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Mechanistic insights into regulated cargo binding by ACAP1 protein
J.Biol.Chem., 287, 2012
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4MAL
 | | TPR3 of FimV from P. aeruginosa (PAO1) | | Descriptor: | Motility protein FimV | | Authors: | Nguyen, Y, Zhang, K, Daniel-Ivad, M, Sugiman-Marangos, S.N, Junop, M.S, Burrows, L.L, Howell, P.L. | | Deposit date: | 2013-08-16 | | Release date: | 2014-08-20 | | Last modified: | 2016-02-24 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Crystal structure of TPR2 from FimV
To be Published
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3U9G
 | | Crystal structure of the Zinc finger antiviral protein | | Descriptor: | ZINC ION, Zinc finger CCCH-type antiviral protein 1 | | Authors: | Chen, S, Xu, Y, Zhang, K, Wang, X, Sun, J, Gao, G, Liu, Y. | | Deposit date: | 2011-10-18 | | Release date: | 2012-03-14 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.801 Å) | | Cite: | Structure of N-terminal domain of ZAP indicates how a zinc-finger protein recognizes complex RNA.
Nat.Struct.Mol.Biol., 19, 2012
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4NPH
 | | Crystal structure of SsaN from Salmonella enterica | | Descriptor: | Probable secretion system apparatus ATP synthase SsaN | | Authors: | Sugiman-Marangos, S.N, Zhang, K, Cooper, C.A, Coombes, B.K, Junop, M.S. | | Deposit date: | 2013-11-21 | | Release date: | 2014-07-23 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.09 Å) | | Cite: | Crystal structure of SsaN from Salmonella enterica
J.Biol.Chem., 2014
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4OIY
 | | Crystal structure of Sec7p catalytic domain | | Descriptor: | MAGNESIUM ION, Protein transport protein SEC7 | | Authors: | Qiu, B, Zhang, K, Sun, F. | | Deposit date: | 2014-01-20 | | Release date: | 2014-07-02 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | C-terminal motif within Sec7 domain regulates guanine nucleotide exchange activity via tuning protein conformation
Biochem.Biophys.Res.Commun., 446, 2014
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3ZIF
 | | Cryo-EM structures of two intermediates provide insight into adenovirus assembly and disassembly | | Descriptor: | HEXON PROTEIN, PENTON PROTEIN, PIX, ... | | Authors: | Cheng, L, Huang, X, Li, X, Xiong, W, Sun, W, Yang, C, Zhang, K, Wang, Y, Liu, H, Ji, G, Sun, F, Zheng, C, Zhu, P. | | Deposit date: | 2013-01-09 | | Release date: | 2014-01-22 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (4.5 Å) | | Cite: | Cryo-Em Structures of Two Bovine Adenovirus Type 3 Intermediates
Virology, 450, 2014
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6K61
 | | Cryo-EM structure of the tetrameric photosystem I from a heterocyst-forming cyanobacterium Anabaena sp. PCC7120 | | Descriptor: | 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, ... | | Authors: | Zheng, L, Li, Y, Li, X, Zhong, Q, Li, N, Zhang, K, Zhang, Y, Chu, H, Ma, C, Li, G, Zhao, J, Gao, N. | | Deposit date: | 2019-05-31 | | Release date: | 2019-10-09 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (2.37 Å) | | Cite: | Structural and functional insights into the tetrameric photosystem I from heterocyst-forming cyanobacteria.
Nat.Plants, 5, 2019
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7YCH
 | | Cryo-EM structure of Tetrahymena ribozyme conformation 3 undergoing the first-step self-splicing | | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, RNA (393-MER), ... | | Authors: | Zhang, X, Li, S, Pintilie, G, Palo, M.Z, Zhang, K. | | Deposit date: | 2022-07-01 | | Release date: | 2023-07-05 | | Last modified: | 2023-08-16 | | Method: | ELECTRON MICROSCOPY (3.09 Å) | | Cite: | Snapshots of the first-step self-splicing of Tetrahymena ribozyme revealed by cryo-EM.
Nucleic Acids Res., 51, 2023
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7YCG
 | | Cryo-EM structure of Tetrahymena ribozyme conformation 2 undergoing the first-step self-splicing | | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, RNA (393-MER), ... | | Authors: | Zhang, X, Li, S, Pintilie, G, Palo, M.Z, Zhang, K. | | Deposit date: | 2022-07-01 | | Release date: | 2023-07-05 | | Last modified: | 2023-08-16 | | Method: | ELECTRON MICROSCOPY (3.18 Å) | | Cite: | Snapshots of the first-step self-splicing of Tetrahymena ribozyme revealed by cryo-EM.
Nucleic Acids Res., 51, 2023
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7YCI
 | | Cryo-EM structure of Tetrahymena ribozyme conformation 4 undergoing the first-step self-splicing | | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, RNA (389-MER), ... | | Authors: | Zhang, X, Li, S, Pintilie, G, Palo, M.Z, Zhang, K. | | Deposit date: | 2022-07-01 | | Release date: | 2023-07-05 | | Last modified: | 2023-08-16 | | Method: | ELECTRON MICROSCOPY (2.98 Å) | | Cite: | Snapshots of the first-step self-splicing of Tetrahymena ribozyme revealed by cryo-EM.
Nucleic Acids Res., 51, 2023
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7YC8
 | | Cryo-EM structure of Tetrahymena ribozyme conformation 1 undergoing the first-step self-splicing | | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, RNA (388-MER) | | Authors: | Zhang, X, Li, S, Pintilie, G, Palo, M.Z, Zhang, K. | | Deposit date: | 2022-07-01 | | Release date: | 2023-07-05 | | Last modified: | 2023-08-16 | | Method: | ELECTRON MICROSCOPY (4.14 Å) | | Cite: | Snapshots of the first-step self-splicing of Tetrahymena ribozyme revealed by cryo-EM.
Nucleic Acids Res., 51, 2023
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7YGA
 | | Cryo-EM structure of Tetrahymena ribozyme conformation 2 undergoing the second-step self-splicing | | Descriptor: | MAGNESIUM ION, RNA (393-MER), RNA (5'-R(*CP*CP*CP*UP*CP*U)-3'), ... | | Authors: | Li, S, Michael, Z.P, Zhang, X, Greg, P, Zhang, K. | | Deposit date: | 2022-07-11 | | Release date: | 2023-03-29 | | Method: | ELECTRON MICROSCOPY (2.35 Å) | | Cite: | Snapshots of the second-step self-splicing of Tetrahymena ribozyme revealed by cryo-EM.
Nat Commun, 14, 2023
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7YG8
 | | Cryo-EM structure of Tetrahymena ribozyme conformation 5 undergoing the second-step self-splicing | | Descriptor: | MAGNESIUM ION, RNA (387-MER), RNA (5'-R(*CP*CP*CP*UP*C)-3'), ... | | Authors: | Li, S, Michael, Z.P, Zhang, X, Greg, P, Zhang, K. | | Deposit date: | 2022-07-11 | | Release date: | 2023-03-29 | | Method: | ELECTRON MICROSCOPY (2.97 Å) | | Cite: | Snapshots of the second-step self-splicing of Tetrahymena ribozyme revealed by cryo-EM.
Nat Commun, 14, 2023
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7YGD
 | | Cryo-EM structure of Tetrahymena ribozyme conformation 6 undergoing the second-step self-splicing | | Descriptor: | MAGNESIUM ION, RNA (384-MER), RNA (5'-R(*CP*C)-3'), ... | | Authors: | Li, S, Michael, Z.P, Zhang, X, Greg, P, Zhang, K. | | Deposit date: | 2022-07-11 | | Release date: | 2023-03-29 | | Method: | ELECTRON MICROSCOPY (3.41 Å) | | Cite: | Snapshots of the second-step self-splicing of Tetrahymena ribozyme revealed by cryo-EM.
Nat Commun, 14, 2023
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7YGC
 | | Cryo-EM structure of Tetrahymena ribozyme conformation 4 undergoing the second-step self-splicing | | Descriptor: | MAGNESIUM ION, RNA (393-MER), RNA (5'-R(*CP*CP*CP*UP*CP*UP*UP*AP*AP*CP*C)-3'), ... | | Authors: | Li, S, Michael, Z.P, Zhang, X, Greg, P, Zhang, K. | | Deposit date: | 2022-07-11 | | Release date: | 2023-03-29 | | Last modified: | 2023-04-05 | | Method: | ELECTRON MICROSCOPY (2.65 Å) | | Cite: | Snapshots of the second-step self-splicing of Tetrahymena ribozyme revealed by cryo-EM.
Nat Commun, 14, 2023
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7YGB
 | | Cryo-EM structure of Tetrahymena ribozyme conformation 3 undergoing the second-step self-splicing | | Descriptor: | MAGNESIUM ION, RNA (393-MER), RNA (5'-R(*CP*CP*CP*UP*CP*UP*UP*AP*AP*CP*C)-3'), ... | | Authors: | Li, S, Michael, Z.P, Zhang, X, Greg, P, Zhang, K. | | Deposit date: | 2022-07-11 | | Release date: | 2023-03-29 | | Method: | ELECTRON MICROSCOPY (2.62 Å) | | Cite: | Snapshots of the second-step self-splicing of Tetrahymena ribozyme revealed by cryo-EM.
Nat Commun, 14, 2023
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7YG9
 | | Cryo-EM structure of Tetrahymena ribozyme conformation 1 undergoing the second-step self-splicing | | Descriptor: | MAGNESIUM ION, RNA (391-MER), RNA (5'-R(*CP*CP*CP*UP*CP*U)-3'), ... | | Authors: | Li, S, Michael, Z.P, Zhang, X, Greg, P, Zhang, K. | | Deposit date: | 2022-07-11 | | Release date: | 2023-03-29 | | Method: | ELECTRON MICROSCOPY (2.68 Å) | | Cite: | Snapshots of the second-step self-splicing of Tetrahymena ribozyme revealed by cryo-EM.
Nat Commun, 14, 2023
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7CFM
 | | Cryo-EM structure of the P395-bound GPBAR-Gs complex | | Descriptor: | 2-(ethylamino)-6-[3-(4-propan-2-ylphenyl)propanoyl]-7,8-dihydro-5H-pyrido[4,3-d]pyrimidine-4-carboxamide, CHOLESTEROL, G-protein coupled bile acid receptor 1, ... | | Authors: | Yang, F, Mao, C, Guo, L, Lin, J, Ming, Q, Xiao, P, Wu, X, Shen, Q, Guo, S, Shen, D, Lu, R, Zhang, L, Huang, S, Ping, Y, Zhang, C, Ma, C, Zhang, K, Liang, X, Shen, Y, Nan, F, Yi, F, Luca, V, Zhou, J, Jiang, C, Sun, J, Xie, X, Yu, X, Zhang, Y. | | Deposit date: | 2020-06-27 | | Release date: | 2020-09-09 | | Last modified: | 2020-12-02 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Structural basis of GPBAR activation and bile acid recognition.
Nature, 587, 2020
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