3N9K
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![BU of 3n9k by Molmil](/molmil-images/mine/3n9k) | F229A/E292S Double Mutant of Exo-beta-1,3-glucanase from Candida albicans in Complex with Laminaritriose at 1.7 A | Descriptor: | CALCIUM ION, Glucan 1,3-beta-glucosidase, beta-D-glucopyranose-(1-3)-beta-D-glucopyranose, ... | Authors: | Nakatani, Y, Cutfield, S.M, Cutfield, J.F. | Deposit date: | 2010-05-30 | Release date: | 2010-09-15 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Carbohydrate binding sites in Candida albicans exo-beta-1,3-glucanase and the role of the Phe-Phe 'clamp' at the active site entrance Febs J., 277, 2010
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5B13
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![BU of 5b13 by Molmil](/molmil-images/mine/5b13) | Crystal structure of phycoerythrin | Descriptor: | PHYCOCYANOBILIN, PHYCOUROBILIN, Phycoerythrin alpha subunit, ... | Authors: | Tanaka, Y, Gai, Z, Kishimura, H. | Deposit date: | 2015-11-18 | Release date: | 2016-10-05 | Last modified: | 2020-02-26 | Method: | X-RAY DIFFRACTION (2.094 Å) | Cite: | Structural properties of phycoerythrin from dulse palmaria palmata J FOOD BIOCHEM., 2016
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5B3D
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![BU of 5b3d by Molmil](/molmil-images/mine/5b3d) | Structure of a flagellar type III secretion chaperone, FlgN | Descriptor: | Flagella synthesis protein FlgN | Authors: | Nakanishi, Y, Kinoshita, M, Namba, K, Minamino, T, Imada, K. | Deposit date: | 2016-02-15 | Release date: | 2016-06-01 | Last modified: | 2020-02-26 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Rearrangements of alpha-helical structures of FlgN chaperone control the binding affinity for its cognate substrates during flagellar type III export Mol.Microbiol., 101, 2016
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8K71
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![BU of 8k71 by Molmil](/molmil-images/mine/8k71) | Factor-inhibiting hypoxia-inducible factor in complex with Zn(II) and 2-(3-hydroxy-2-((2-((naphthalen-2-ylmethyl)sulfonyl)acetyl)imino)-2,3-dihydrothiazol-4-yl)acetic acid | Descriptor: | 2-[(2~{Z})-2-[2-(naphthalen-2-ylmethylsulfonyl)ethanoylimino]-3-oxidanyl-1,3-thiazol-4-yl]ethanoic acid, GLYCEROL, Hypoxia-inducible factor 1-alpha inhibitor, ... | Authors: | Nakashima, Y, Corner, T.P, Teo, R.Z.R, Brewitz, L, Schofield, C.J. | Deposit date: | 2023-07-26 | Release date: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.23 Å) | Cite: | Structure-guided optimisation of N -hydroxythiazole-derived inhibitors of factor inhibiting hypoxia-inducible factor-alpha. Chem Sci, 14, 2023
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8K72
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![BU of 8k72 by Molmil](/molmil-images/mine/8k72) | Factor-inhibiting hypoxia-inducible factor in complex with Zn(II) and 2-(3-hydroxy-2-((3-(phenylsulfonamido)propanoyl)imino)-2,3-dihydrothiazol-4-yl)acetic acid | Descriptor: | 2-[(2~{Z})-3-oxidanyl-2-[3-(phenylsulfonylamino)propanoylimino]-1,3-thiazol-4-yl]ethanoic acid, GLYCEROL, Hypoxia-inducible factor 1-alpha inhibitor, ... | Authors: | Nakashima, Y, Corner, T.P, Teo, R.Z.R, Brewitz, L, Schofield, C.J. | Deposit date: | 2023-07-26 | Release date: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Structure-guided optimisation of N -hydroxythiazole-derived inhibitors of factor inhibiting hypoxia-inducible factor-alpha. Chem Sci, 14, 2023
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8K73
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![BU of 8k73 by Molmil](/molmil-images/mine/8k73) | Factor-inhibiting hypoxia-inducible factor in complex with Zn(II) and 2-(3-hydroxy-2-((1-(phenylsulfonyl)pyrrolidine-3-carbonyl)imino)-2,3-dihydrothiazol-4-yl)acetic acid | Descriptor: | 2-[(2~{Z})-3-oxidanyl-2-[(3~{R})-1-(phenylsulfonyl)pyrrolidin-3-yl]carbonylimino-1,3-thiazol-4-yl]ethanoic acid, GLYCEROL, Hypoxia-inducible factor 1-alpha inhibitor, ... | Authors: | Nakashima, Y, Corner, T.P, Teo, R.Z.R, Brewitz, L, Schofield, C.J. | Deposit date: | 2023-07-26 | Release date: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | Structure-guided optimisation of N -hydroxythiazole-derived inhibitors of factor inhibiting hypoxia-inducible factor-alpha. Chem Sci, 14, 2023
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4IC2
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![BU of 4ic2 by Molmil](/molmil-images/mine/4ic2) | Crystal structure of the XIAP RING domain | Descriptor: | E3 ubiquitin-protein ligase XIAP, NICKEL (II) ION, ZINC ION | Authors: | Linke, K, Nakatani, Y, Day, C.L. | Deposit date: | 2012-12-09 | Release date: | 2012-12-19 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Regulation of ubiquitin transfer by XIAP, a dimeric RING E3 ligase Biochem.J., 450, 2013
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4NWZ
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![BU of 4nwz by Molmil](/molmil-images/mine/4nwz) | Structure of bacterial type II NADH dehydrogenase from Caldalkalibacillus thermarum at 2.5A resolution | Descriptor: | FAD-dependent pyridine nucleotide-disulfide oxidoreductase, FLAVIN-ADENINE DINUCLEOTIDE | Authors: | Nakatani, Y, Heikal, A, Lott, J.S, Sazanov, L.A, Baker, E.N, Cook, G.M. | Deposit date: | 2013-12-07 | Release date: | 2014-02-19 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure of the bacterial type II NADH dehydrogenase: a monotopic membrane protein with an essential role in energy generation. Mol.Microbiol., 91, 2014
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2D5K
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![BU of 2d5k by Molmil](/molmil-images/mine/2d5k) | Crystal structure of Dps from Staphylococcus aureus | Descriptor: | Dps family protein, GLYCEROL | Authors: | Tanaka, Y, Yao, M, Watanabe, N, Tanaka, I. | Deposit date: | 2005-11-02 | Release date: | 2006-10-17 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Nucleoid compaction by MrgA(Asp56Ala/Glu60Ala) does not contribute to staphylococcal cell survival against oxidative stress and phagocytic killing by macrophages FEMS Microbiol. Lett., 360, 2014
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7BMI
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![BU of 7bmi by Molmil](/molmil-images/mine/7bmi) | Aspartyl/Asparaginyl beta-hydroxylase (AspH) oxygenase and TPR domains in complex with manganese, 3-fluoropyridine-2,4-dicarboxylic acid, and factor X substrate peptide fragment (39mer-4Ser) | Descriptor: | 3-fluoranylpyridine-2,4-dicarboxylic acid, Aspartyl/asparaginyl beta-hydroxylase, Coagulation factor X, ... | Authors: | Nakashima, Y, Brewitz, L, Schofield, C.J. | Deposit date: | 2021-01-20 | Release date: | 2021-06-02 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.66 Å) | Cite: | Fluorinated derivatives of pyridine-2,4-dicarboxylate are potent inhibitors of human 2-oxoglutarate dependent oxygenases J Fluor Chem, 247, 2021
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7BMJ
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![BU of 7bmj by Molmil](/molmil-images/mine/7bmj) | Aspartyl/Asparaginyl beta-hydroxylase (AspH) oxygenase and TPR domains in complex with manganese, 5-fluoropyridine-2,4-dicarboxylic acid, and factor X substrate peptide fragment (39mer-4Ser) | Descriptor: | 5-fluoranylpyridine-2,4-dicarboxylic acid, Aspartyl/asparaginyl beta-hydroxylase, Coagulation factor X, ... | Authors: | Nakashima, Y, Brewitz, L, Schofield, C.J. | Deposit date: | 2021-01-20 | Release date: | 2021-06-02 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Fluorinated derivatives of pyridine-2,4-dicarboxylate are potent inhibitors of human 2-oxoglutarate dependent oxygenases J Fluor Chem, 247, 2021
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2DCM
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![BU of 2dcm by Molmil](/molmil-images/mine/2dcm) | The Crystal Structure of S603A Mutated Prolyl Tripeptidyl Aminopeptidase Complexed with Substrate | Descriptor: | GLYCYLALANYL-N-2-NAPHTHYL-L-PROLINEAMIDE, dipeptidyl aminopeptidase IV, putative | Authors: | Nakajima, Y, Ito, K, Xu, Y, Yamada, N, Onohara, Y, Yoshimoto, T. | Deposit date: | 2006-01-09 | Release date: | 2006-09-19 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal Structure and Mechanism of Tripeptidyl Activity of Prolyl Tripeptidyl Aminopeptidase from Porphyromonas gingivalis J.Mol.Biol., 362, 2006
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5YHF
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![BU of 5yhf by Molmil](/molmil-images/mine/5yhf) | Crystal structure of SecDF in Super-membrane-facing form | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, DI(HYDROXYETHYL)ETHER, Protein translocase subunit SecDF | Authors: | Tanaka, Y, Tsukazaki, T, Yoshikaie, K, Furukawa, A. | Deposit date: | 2017-09-28 | Release date: | 2018-02-14 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Remote Coupled Drastic beta-Barrel to beta-Sheet Transition of the Protein Translocation Motor. Structure, 26, 2018
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6KR0
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![BU of 6kr0 by Molmil](/molmil-images/mine/6kr0) | Crystal structure of HL homo-diabody | Descriptor: | HL diabody | Authors: | Tanaka, Y. | Deposit date: | 2019-08-20 | Release date: | 2020-08-26 | Last modified: | 2021-09-08 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Association behavior and control of the quality of cancer therapeutic bispecific diabodies expressed in Escherichia coli Biochem Eng J, 160, 2020
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2D5L
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![BU of 2d5l by Molmil](/molmil-images/mine/2d5l) | Crystal Structure of Prolyl Tripeptidyl Aminopeptidase from Porphyromonas gingivalis | Descriptor: | SULFATE ION, dipeptidyl aminopeptidase IV, putative | Authors: | Nakajima, Y, Ito, K, Xu, Y, Yamada, N, Onohara, Y, Yoshimoto, T. | Deposit date: | 2005-11-02 | Release date: | 2006-09-19 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal Structure and Mechanism of Tripeptidyl Activity of Prolyl Tripeptidyl Aminopeptidase from Porphyromonas gingivalis J.Mol.Biol., 362, 2006
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2DQ6
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![BU of 2dq6 by Molmil](/molmil-images/mine/2dq6) | Crystal Structure of Aminopeptidase N from Escherichia coli | Descriptor: | Aminopeptidase N, SULFATE ION, ZINC ION | Authors: | Nakajima, Y, Onohara, Y, Ito, K, Yoshimoto, T. | Deposit date: | 2006-05-22 | Release date: | 2006-08-01 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Aminopeptidase N (proteobacteria alanyl aminopeptidase) from Escherichia coli: Crystal structure and conformational change of the methionine 260 residue involved in substrate recognition J.Biol.Chem., 281, 2006
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6IGG
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![BU of 6igg by Molmil](/molmil-images/mine/6igg) | Crystal structure of FT condition 1 | Descriptor: | 1,2-ETHANEDIOL, Protein FLOWERING LOCUS T | Authors: | Watanabe, S, Nakamura, Y, Kanehara, K, Inaba, K. | Deposit date: | 2018-09-25 | Release date: | 2019-12-25 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1 Å) | Cite: | High-Resolution Crystal Structure of Arabidopsis FLOWERING LOCUS T Illuminates Its Phospholipid-Binding Site in Flowering. Iscience, 21, 2019
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6IGJ
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![BU of 6igj by Molmil](/molmil-images/mine/6igj) | Crystal structure of FT condition 4 | Descriptor: | MAGNESIUM ION, Protein FLOWERING LOCUS T | Authors: | Watanabe, S, Nakamura, Y, Kanehara, K, Inaba, K. | Deposit date: | 2018-09-25 | Release date: | 2019-12-25 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.501 Å) | Cite: | High-Resolution Crystal Structure of Arabidopsis FLOWERING LOCUS T Illuminates Its Phospholipid-Binding Site in Flowering. Iscience, 21, 2019
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6IGI
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![BU of 6igi by Molmil](/molmil-images/mine/6igi) | Crystal structure of FT condition 2 | Descriptor: | 1,2-ETHANEDIOL, Protein FLOWERING LOCUS T | Authors: | Watanabe, S, Nakamura, Y, Kanehara, K, Inaba, K. | Deposit date: | 2018-09-25 | Release date: | 2019-12-25 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.33 Å) | Cite: | High-Resolution Crystal Structure of Arabidopsis FLOWERING LOCUS T Illuminates Its Phospholipid-Binding Site in Flowering. Iscience, 21, 2019
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6IGH
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![BU of 6igh by Molmil](/molmil-images/mine/6igh) | Crystal structure of FT condition3 | Descriptor: | 1,2-ETHANEDIOL, Protein FLOWERING LOCUS T | Authors: | Watanabe, S, Nakamura, Y, Kanehara, K, Inaba, K. | Deposit date: | 2018-09-25 | Release date: | 2019-12-25 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.01 Å) | Cite: | High-Resolution Crystal Structure of Arabidopsis FLOWERING LOCUS T Illuminates Its Phospholipid-Binding Site in Flowering. Iscience, 21, 2019
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2YXY
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![BU of 2yxy by Molmil](/molmil-images/mine/2yxy) | Crystarl structure of Hypothetical conserved protein, GK0453 | Descriptor: | Hypothetical conserved protein, GK0453 | Authors: | Nakamu, Y, Bessho, Y, Padmanabhan, B, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-04-27 | Release date: | 2007-10-30 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of the hypothetical DUF1811-family protein GK0453 from Geobacillus kaustophilus HTA426 Acta Crystallogr.,Sect.F, 69, 2013
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5XI8
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![BU of 5xi8 by Molmil](/molmil-images/mine/5xi8) | Structure and function of the TPR domain | Descriptor: | Beta-barrel assembly-enhancing protease | Authors: | Tanaka, Y, Tsukazaki, T. | Deposit date: | 2017-04-26 | Release date: | 2017-10-18 | Last modified: | 2017-12-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The TPR domain of BepA is required for productive interaction with substrate proteins and the beta-barrel assembly machinery complex. Mol. Microbiol., 106, 2017
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5Z3C
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![BU of 5z3c by Molmil](/molmil-images/mine/5z3c) | Glycosidase E178A | Descriptor: | GLYCEROL, Glycoside hydrolase 15-related protein | Authors: | Tanaka, Y, Chen, M, Tagami, T, Yao, M, Kimura, A. | Deposit date: | 2018-01-05 | Release date: | 2019-05-15 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural insights reveal the second base catalyst of isomaltose glucohydrolase. Febs J., 289, 2022
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5Z3D
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![BU of 5z3d by Molmil](/molmil-images/mine/5z3d) | Glycosidase F290Y | Descriptor: | CITRIC ACID, GLYCEROL, Glycoside hydrolase 15-related protein | Authors: | Tanaka, Y, Chen, M, Tagami, T, Yao, M, Kimura, A. | Deposit date: | 2018-01-05 | Release date: | 2019-05-15 | Last modified: | 2022-02-23 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | Structural insights reveal the second base catalyst of isomaltose glucohydrolase. Febs J., 289, 2022
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5Z3B
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![BU of 5z3b by Molmil](/molmil-images/mine/5z3b) | Glycosidase Y48F | Descriptor: | CITRIC ACID, GLYCEROL, Glycoside hydrolase 15-related protein | Authors: | Tanaka, Y, Chen, M, Tagami, T, Yao, M, Kimura, A. | Deposit date: | 2018-01-05 | Release date: | 2019-05-15 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | Structural insights reveal the second base catalyst of isomaltose glucohydrolase. Febs J., 289, 2022
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