7BMI
Aspartyl/Asparaginyl beta-hydroxylase (AspH) oxygenase and TPR domains in complex with manganese, 3-fluoropyridine-2,4-dicarboxylic acid, and factor X substrate peptide fragment (39mer-4Ser)
Summary for 7BMI
Entry DOI | 10.2210/pdb7bmi/pdb |
Descriptor | Aspartyl/asparaginyl beta-hydroxylase, Coagulation factor X, MANGANESE (II) ION, ... (5 entities in total) |
Functional Keywords | aspartyl/asparaginyl beta-hydroxylase, dioxygenase, oxidoreductase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 53835.77 |
Authors | Nakashima, Y.,Brewitz, L.,Schofield, C.J. (deposition date: 2021-01-20, release date: 2021-06-02, Last modification date: 2024-11-20) |
Primary citation | Brewitz, L.,Nakashima, Y.,Tumber, A.,Salah, E.,Schofield, C.J. Fluorinated derivatives of pyridine-2,4-dicarboxylate are potent inhibitors of human 2-oxoglutarate dependent oxygenases J Fluor Chem, 247:109804-, 2021 Cited by DOI: 10.1016/j.jfluchem.2021.109804PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.66 Å) |
Structure validation
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