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3KMO
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BU of 3kmo by Molmil
Crystal Structure of the Human GST Pi C47S/Y108V Double Mutant in Complex with the Ethacrynic Acid-Glutathione Conjugate (Grown in the Absence of the Reducing Agent DTT)
Descriptor: CALCIUM ION, ETHACRYNIC ACID, GLUTATHIONE, ...
Authors:Parker, L.J.
Deposit date:2009-11-11
Release date:2010-03-23
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Diuretic drug binding to human glutathione transferase P1-1: potential role of CYS101 revealed in the double mutant C47S/Y108V
To be Published
3DNF
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BU of 3dnf by Molmil
Structure of (E)-4-Hydroxy-3-methyl-but-2-enyl Diphosphate Reductase, the Terminal Enzyme of the Non-Mevalonate Pathway
Descriptor: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase, FE3-S4 CLUSTER, GLYCEROL
Authors:Rekittke, I.
Deposit date:2008-07-02
Release date:2008-12-30
Last modified:2020-09-09
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structure of (E)-4-Hydroxy-3-methyl-but-2-enyl Diphosphate Reductase, the Terminal Enzyme of the Non-Mevalonate Pathway.
J.Am.Chem.Soc., 2008
4NJC
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BU of 4njc by Molmil
RNA Polymerase interacting protein YkzG from Geobacillus stearothermophilus
Descriptor: Geobacillus stearothermophilus YkzG
Authors:Keller, A.N, Lewis, P.J.
Deposit date:2013-11-09
Release date:2014-08-20
Last modified:2014-10-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:epsilon, a New Subunit of RNA Polymerase Found in Gram-Positive Bacteria
J.Bacteriol., 196, 2014
4AGC
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BU of 4agc by Molmil
CRYSTAL STRUCTURE OF VEGFR2 (JUXTAMEMBRANE AND KINASE DOMAINS) IN COMPLEX WITH AXITINIB (AG-013736) (N-Methyl-2-(3-((E)-2-pyridin-2-yl- vinyl)-1H-indazol-6-ylsulfanyl)-benzamide)
Descriptor: AXITINIB, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2
Authors:Mctigue, M, Deng, Y, Ryan, K, Brooun, A, Diehl, W, Kania, R.S.
Deposit date:2012-01-26
Release date:2012-09-26
Last modified:2024-08-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Molecular Conformations, Interactions, and Properties Associated with Drug Efficiency and Clinical Performance Among Vegfr Tk Inhibitors.
Proc.Natl.Acad.Sci.USA, 109, 2012
4ASE
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BU of 4ase by Molmil
CRYSTAL STRUCTURE OF VEGFR2 (JUXTAMEMBRANE AND KINASE DOMAINS) IN COMPLEX WITH TIVOZANIB (AV-951)
Descriptor: TIVOZANIB, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2
Authors:McTigue, M, Deng, Y, Ryan, K, Brooun, A, Diehl, W, Stewart, A.
Deposit date:2012-04-30
Release date:2012-09-26
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Molecular Conformations, Interactions, and Properties Associated with Drug Efficiency and Clinical Performance Among Vegfr Tk Inhibitors.
Proc.Natl.Acad.Sci.USA, 109, 2012
4AGD
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BU of 4agd by Molmil
CRYSTAL STRUCTURE OF VEGFR2 (JUXTAMEMBRANE AND KINASE DOMAINS) IN COMPLEX WITH SUNITINIB (SU11248) (N-2-diethylaminoethyl)-5-((Z)-(5- fluoro-2-oxo-1H-indol-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3- carboxamide)
Descriptor: N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carbo xamide, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2
Authors:McTigue, M, Deng, Y, Ryan, K, Brooun, A, Diehl, W, Stewart, A.
Deposit date:2012-01-26
Release date:2012-09-26
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Molecular Conformations, Interactions, and Properties Associated with Drug Efficiency and Clinical Performance Among Vegfr Tk Inhibitors.
Proc.Natl.Acad.Sci.USA, 109, 2012
4ASD
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BU of 4asd by Molmil
Crystal Structure of VEGFR2 (Juxtamembrane and Kinase Domains) in Complex with SORAFENIB (BAY 43-9006)
Descriptor: 4-{4-[({[4-CHLORO-3-(TRIFLUOROMETHYL)PHENYL]AMINO}CARBONYL)AMINO]PHENOXY}-N-METHYLPYRIDINE-2-CARBOXAMIDE, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2
Authors:McTigue, M, Deng, Y, Ryan, K, Brooun, A, Diehl, W, Stewart, A.
Deposit date:2012-04-30
Release date:2012-09-26
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Molecular Conformations, Interactions, and Properties Associated with Drug Efficiency and Clinical Performance Among Vegfr Tk Inhibitors.
Proc.Natl.Acad.Sci.USA, 109, 2012
1QME
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BU of 1qme by Molmil
PENICILLIN-BINDING PROTEIN 2X (PBP-2X)
Descriptor: PENICILLIN-BINDING PROTEIN 2X, SULFATE ION
Authors:Gordon, E.J, Mouz, N, Duee, E, Dideberg, O.
Deposit date:1999-09-28
Release date:2000-05-25
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Crystal Structure of the Penicillin-Binding Protein 2X from Streptococcus Pneumoniae and its Acyl-Enzyme Form: Implication in Drug Resistance.
J.Mol.Biol., 299, 2000
1QMF
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BU of 1qmf by Molmil
PENICILLIN-BINDING PROTEIN 2X (PBP-2X) ACYL-ENZYME COMPLEX
Descriptor: 2-[CARBOXY-(2-FURAN-2-YL-2-METHOXYIMINO-ACETYLAMINO)-METHYL]-5-METHYL-3,6-DIHYDRO-2H-[1,3]THIAZINE-4-CARBOXYLIC ACID, CEFUROXIME (OCT-3-ENE FORM), PENICILLIN-BINDING PROTEIN 2X
Authors:Gordon, E.J, Mouz, N, Duee, E, Dideberg, O.
Deposit date:1999-09-28
Release date:2000-05-25
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The Crystal Structure of the Penicillin Binding Protein 2X from Streptococcus Pneumoniae and its Acyl-Enzyme Form: Implication in Drug Resistance
J.Mol.Biol., 299, 2000
2Q3E
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BU of 2q3e by Molmil
Structure of human UDP-glucose dehydrogenase complexed with NADH and UDP-glucose
Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, CHLORIDE ION, UDP-glucose 6-dehydrogenase, ...
Authors:Kavanagh, K.L, Guo, K, Bunkoczi, G, Savitsky, P, Pilka, E, Bhatia, C, Smee, C, Berridge, G, von Delft, F, Wiegelt, J, Arrowsmith, C, Sundstrom, M, Edwards, A, Oppermann, U, Structural Genomics Consortium (SGC)
Deposit date:2007-05-30
Release date:2007-07-03
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure and mechanism of human UDP-glucose 6-dehydrogenase.
J.Biol.Chem., 286, 2011
2JP2
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BU of 2jp2 by Molmil
Solution structure and resonance assignment of the N-terminal EVH1 domain from the human Spred2 protein (Sprouty-related protein with EVH1 domain isoform 2)
Descriptor: Sprouty-related, EVH1 domain-containing protein 2
Authors:Fossi, M, Zimmermann, J, Jarchau, T, Lemak, A, Walter, U, Wiegelt, J, Sundstrom, M, Arrowsmith, C, Edwards, A, Oschkinat, H, Ball, L.J, Structural Genomics Consortium (SGC)
Deposit date:2007-04-18
Release date:2007-05-15
Last modified:2024-05-08
Method:SOLUTION NMR
Cite:1H, 13C and 15N resonance assignment of the human Spred2 EVH1 domain
J.Biomol.NMR, 29, 2004
1PMD
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BU of 1pmd by Molmil
PENICILLIN-BINDING PROTEIN 2X (PBP-2X)
Descriptor: PEPTIDOGLYCAN SYNTHESIS MULTIFUNCTIONAL ENZYME
Authors:Pares, S, Mouz, N, Dideberg, O.
Deposit date:1996-02-05
Release date:1997-02-05
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:X-ray structure of Streptococcus pneumoniae PBP2x, a primary penicillin target enzyme.
Nat.Struct.Biol., 3, 1996
2JRZ
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BU of 2jrz by Molmil
Solution structure of the Bright/ARID domain from the human JARID1C protein.
Descriptor: Histone demethylase JARID1C
Authors:Koehler, C, Bishop, S, Dowler, E.F, Diehl, A, Schmieder, P, Leidert, M, Sundstrom, M, Arrowsmith, C.H, Wiegelt, J, Edwards, A, Oschkinat, H, Ball, L.J, Structural Genomics Consortium (SGC)
Deposit date:2007-06-29
Release date:2007-07-10
Last modified:2024-05-08
Method:SOLUTION NMR
Cite:Backbone and sidechain 1H, 13C and 15N resonance assignments of the Bright/ARID domain from the human JARID1C (SMCX) protein.
Biomol.Nmr Assign., 2, 2008

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数据于2024-08-28公开中

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