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7JIG
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BU of 7jig by Molmil
HRAS A59T GppNHp crystal 2
Descriptor: GTPase HRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
Authors:Johnson, C.W, Haigis, K.M.
Deposit date:2020-07-23
Release date:2022-03-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.322 Å)
Cite:Regulation of GTPase function by autophosphorylation.
Mol.Cell, 82, 2022
8TLX
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BU of 8tlx by Molmil
Crystal structure of MBP and AF9 AHD fusion protein 3AQA in complex with peptidomimetic inhibitor 21a
Descriptor: GLYCEROL, MBP and AF9 AHD fusion protein 3AQA, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ...
Authors:Yang, Y, Nikolovska-Coleska, Z.
Deposit date:2023-07-27
Release date:2024-05-29
Method:X-RAY DIFFRACTION (2.097 Å)
Cite:Structural studies of intrinsically disordered MLL-fusion protein AF9 in complex with peptidomimetic inhibitors.
Protein Sci., 33, 2024
8TLV
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BU of 8tlv by Molmil
Crystal structure of MBP and AF9 AHD fusion protein 4AQK in complex with peptidomimetic inhibitor 28
Descriptor: GLUTATHIONE, MBP and AF9 AHD fusion protein 4AQK, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ...
Authors:Yang, Y, Nikolovska-Coleska, Z.
Deposit date:2023-07-27
Release date:2024-05-29
Method:X-RAY DIFFRACTION (2.659 Å)
Cite:Structural studies of intrinsically disordered MLL-fusion protein AF9 in complex with peptidomimetic inhibitors.
Protein Sci., 33, 2024
8TLW
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BU of 8tlw by Molmil
Crystal structure of MBP and AF9 AHD fusion protein 3AQA in complex with peptidomimetic inhibitor 28
Descriptor: MBP and AF9 AHD fusion protein 3AQA, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, peptidomimetic inhibitor 28
Authors:Yang, Y, Nikolovska-Coleska, Z.
Deposit date:2023-07-27
Release date:2024-05-29
Method:X-RAY DIFFRACTION (2.106 Å)
Cite:Structural studies of intrinsically disordered MLL-fusion protein AF9 in complex with peptidomimetic inhibitors.
Protein Sci., 33, 2024
7KMR
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BU of 7kmr by Molmil
Crystal structure analysis of human KRAS mutant
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Isoform 2B of GTPase KRas
Authors:Seo, H.-S, Dhe-Paganon, S.
Deposit date:2020-11-03
Release date:2021-11-10
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:Regulation of GTPase function by autophosphorylation.
Mol.Cell, 82, 2022
7X6S
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BU of 7x6s by Molmil
lymphocytic choriomeningitis virus RNA-dependent RNA polymerase (LCMV-L protein)
Descriptor: MANGANESE (II) ION, RNA-directed RNA polymerase L
Authors:Liu, L, Lou, Z.
Deposit date:2022-03-08
Release date:2023-09-13
Last modified:2023-09-27
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure basis for allosteric regulation of lymphocytic choriomeningitis virus polymerase function by Z matrix protein.
Protein Cell, 14, 2023
7X6V
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BU of 7x6v by Molmil
lymphocytic choriomeningitis virus polymerase- Matrix Z Protein Complex (LCMV L-Z Complex)
Descriptor: MANGANESE (II) ION, RING finger protein Z, RNA-directed RNA polymerase L, ...
Authors:Liu, L, Lou, Z.
Deposit date:2022-03-08
Release date:2023-09-13
Last modified:2023-09-27
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structure basis for allosteric regulation of lymphocytic choriomeningitis virus polymerase function by Z matrix protein.
Protein Cell, 14, 2023
6B2Q
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BU of 6b2q by Molmil
Dual Inhibition of the Essential Protein Kinases A and B in Mycobacterium tuberculosis
Descriptor: 3-methyl-1-(2-methylpropyl)butyl 4-O-beta-L-gulopyranosyl-beta-D-glucopyranoside, 5-{5-chloro-4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]pyrimidin-2-yl}thiophene-2-sulfonamide, Serine/threonine-protein kinase PknA
Authors:Zuccola, H.J.
Deposit date:2017-09-20
Release date:2018-02-14
Method:X-RAY DIFFRACTION (2.88 Å)
Cite:Mtb PKNA/PKNB Dual Inhibition Provides Selectivity Advantages for Inhibitor Design To Minimize Host Kinase Interactions.
ACS Med Chem Lett, 8, 2017
6B2P
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BU of 6b2p by Molmil
Dual Inhibition of the Essential Protein Kinases A and B in Mycobacterium tuberculosis
Descriptor: 5-{5-chloro-4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]pyrimidin-2-yl}thiophene-2-sulfonamide, Serine/threonine-protein kinase PknB
Authors:Zuccola, H.J.
Deposit date:2017-09-20
Release date:2018-02-14
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:Mtb PKNA/PKNB Dual Inhibition Provides Selectivity Advantages for Inhibitor Design To Minimize Host Kinase Interactions.
ACS Med Chem Lett, 8, 2017
6CIB
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BU of 6cib by Molmil
The structure of YcaO from Methanopyrus kandleri bound with AMPPCP and Mg2+
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, OXAMIC ACID, ...
Authors:Dong, S.-H, Nair, S.K.
Deposit date:2018-02-23
Release date:2018-03-21
Last modified:2018-03-28
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Enzymatic reconstitution of ribosomal peptide backbone thioamidation.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6CI7
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BU of 6ci7 by Molmil
The structure of YcaO from Methanopyrus kandleri bound with AMPPCP and Mg2+
Descriptor: MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, YcaO
Authors:Dong, S.-H, Nair, S.K.
Deposit date:2018-02-23
Release date:2018-03-21
Last modified:2018-03-28
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Enzymatic reconstitution of ribosomal peptide backbone thioamidation.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
8K9F
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BU of 8k9f by Molmil
Cryo-EM structure of the photosynthetic alternative complex III from Chloroflexus aurantiacus at 2.9 angstrom
Descriptor: 1,3-bis(13-methyltetradecanoyloxy)propan-2-yl pentadecanoate, Cytochrome c domain-containing protein, Cytochrome c7-like domain-containing protein, ...
Authors:Xu, X.
Deposit date:2023-08-01
Release date:2024-03-06
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Cryo-EM structure of HQNO-bound Alternative Complex III from the anoxygenic phototrophic bacterium Chloroflexus aurantiacus.
Plant Cell, 2024
8K9E
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BU of 8k9e by Molmil
Cryo-EM structure of the photosynthetic alternative complex III from Chloroflexus aurantiacus at 3.3 angstrom
Descriptor: 1,3-bis(13-methyltetradecanoyloxy)propan-2-yl pentadecanoate, Cytochrome c domain-containing protein, Cytochrome c7-like domain-containing protein, ...
Authors:Xu, X.
Deposit date:2023-08-01
Release date:2024-03-06
Method:ELECTRON MICROSCOPY (3.33 Å)
Cite:Cryo-EM structure of HQNO-bound Alternative Complex III from the anoxygenic phototrophic bacterium Chloroflexus aurantiacus.
Plant Cell, 2024
3PLY
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BU of 3ply by Molmil
Structure of Oxidized P96G Mutant of Amicyanin
Descriptor: Amicyanin, COPPER (II) ION, PHOSPHATE ION, ...
Authors:Sukumar, N, Davidson, V.L.
Deposit date:2010-11-15
Release date:2011-02-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Proline 96 of the copper ligand loop of amicyanin regulates electron transfer from methylamine dehydrogenase by positioning other residues at the protein-protein interface.
Biochemistry, 50, 2011
3SJL
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BU of 3sjl by Molmil
Crystal Structure of the P107S-MauG/pre-Methylamine Dehydrogenase Complex
Descriptor: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ...
Authors:Jensen, L.M.R, Wilmot, C.M.
Deposit date:2011-06-21
Release date:2012-05-02
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Proline 107 is a major determinant in maintaining the structure of the distal pocket and reactivity of the high-spin heme of MauG.
Biochemistry, 51, 2012
3SLE
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BU of 3sle by Molmil
Crystal Structure of the P107C-MauG/pre-Methylamine Dehydrogenase Complex
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, CALCIUM ION, ...
Authors:Yukl, E.T, Wilmot, C.M.
Deposit date:2011-06-24
Release date:2012-05-02
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:Proline 107 is a major determinant in maintaining the structure of the distal pocket and reactivity of the high-spin heme of MauG.
Biochemistry, 51, 2012
3RLM
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BU of 3rlm by Molmil
Structure of the W199F MauG/pre-Methylamine Dehydrogenase complex after treatment with hydrogen peroxide
Descriptor: ACETATE ION, CALCIUM ION, HEME C, ...
Authors:Yukl, E.T, Wilmot, C.M.
Deposit date:2011-04-19
Release date:2011-10-05
Last modified:2011-10-26
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Mutagenesis of tryptophan199 suggests that hopping is required for MauG-dependent tryptophan tryptophylquinone biosynthesis.
Proc.Natl.Acad.Sci.USA, 108, 2011
3RMZ
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BU of 3rmz by Molmil
Crystal Structure of the W199F-MauG/pre-Methylamine Dehydrogenase Complex
Descriptor: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ACETATE ION, ...
Authors:Jensen, L.M.R, Wilmot, C.M.
Deposit date:2011-04-21
Release date:2011-10-05
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Mutagenesis of tryptophan199 suggests that hopping is required for MauG-dependent tryptophan tryptophylquinone biosynthesis.
Proc.Natl.Acad.Sci.USA, 108, 2011
3RN0
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BU of 3rn0 by Molmil
Crystal Structure of the W199K-MauG/pre-Methylamine Dehydrogenase Complex
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, HEME C, ...
Authors:Jensen, L.M.R, Wilmot, C.M.
Deposit date:2011-04-21
Release date:2011-10-05
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Mutagenesis of tryptophan199 suggests that hopping is required for MauG-dependent tryptophan tryptophylquinone biosynthesis.
Proc.Natl.Acad.Sci.USA, 108, 2011
3SVW
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BU of 3svw by Molmil
Crystal Structure of the P107V-MauG/pre-Methylamine Dehydrogenase Complex
Descriptor: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ACETATE ION, ...
Authors:Jensen, L.M.R, Wilmot, C.M.
Deposit date:2011-07-12
Release date:2012-05-02
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Proline 107 is a major determinant in maintaining the structure of the distal pocket and reactivity of the high-spin heme of MauG.
Biochemistry, 51, 2012
2KX4
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BU of 2kx4 by Molmil
Solution structure of Bacteriophage Lambda gpFII
Descriptor: Tail attachment protein
Authors:Maxwell, K.L, Cardarelli, L, Neudecker, P, Davidson, A.R, Ontario Centre for Structural Proteomics (OCSP)
Deposit date:2010-04-26
Release date:2010-07-28
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Phages have adapted the same protein fold to fulfill multiple functions in virion assembly.
Proc.Natl.Acad.Sci.USA, 107, 2010
4OJK
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BU of 4ojk by Molmil
Structure of the cGMP Dependent Protein Kinase II and Rab11b Complex
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Ras-related protein Rab-11B, cGMP-dependent protein kinase 2
Authors:Reger, A.S, Yang, M.P, Guo, E, Kim, C.
Deposit date:2014-01-21
Release date:2014-08-06
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.657 Å)
Cite:Crystal Structure of the cGMP-dependent Protein Kinase II Leucine Zipper and Rab11b Protein Complex Reveals Molecular Details of G-kinase-specific Interactions.
J.Biol.Chem., 289, 2014
6J72
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BU of 6j72 by Molmil
Crystal structure of IniA from Mycobacterium smegmatis with GTP bound
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, Isoniazid inducible gene protein IniA, L(+)-TARTARIC ACID, ...
Authors:Wang, M.F, Guo, X.Y, Hu, J.J, Li, J, Rao, Z.H.
Deposit date:2019-01-16
Release date:2019-09-11
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Mycobacterial dynamin-like protein IniA mediates membrane fission.
Nat Commun, 10, 2019
6J73
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BU of 6j73 by Molmil
Crystal structure of IniA from Mycobacterium smegmatis
Descriptor: Isoniazid inducible gene protein IniA
Authors:Wang, M.F, Guo, X.Y, Hu, J.J, Li, J, Rao, Z.H.
Deposit date:2019-01-16
Release date:2019-09-11
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (3.211 Å)
Cite:Mycobacterial dynamin-like protein IniA mediates membrane fission.
Nat Commun, 10, 2019
7FJJ
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BU of 7fjj by Molmil
human Pol III pre-termination complex
Descriptor: DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ...
Authors:Hou, H, Xu, Y.
Deposit date:2021-08-04
Release date:2021-10-27
Last modified:2021-11-10
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural insights into RNA polymerase III-mediated transcription termination through trapping poly-deoxythymidine.
Nat Commun, 12, 2021

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数据于2024-06-12公开中

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