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3I1C
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BU of 3i1c by Molmil
Crystal Structure of a Novel Engineered Diels-Alderase: DA_20_00_A74I
Descriptor: Diisopropyl-fluorophosphatase, GLYCEROL
Authors:Lambert, A.R, Stoddard, B.L.
Deposit date:2009-06-26
Release date:2009-08-18
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Computational design of an enzyme catalyst for a stereoselective bimolecular Diels-Alder reaction.
Science, 329, 2010
3HYJ
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BU of 3hyj by Molmil
Crystal structure of the N-terminal LAGLIDADG domain of DUF199/WhiA
Descriptor: CHLORIDE ION, GLYCEROL, Protein DUF199/WhiA, ...
Authors:Kaiser, B.K, Clifton, M.C, Shen, B.W, Stoddard, B.L.
Deposit date:2009-06-22
Release date:2009-09-01
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The structure of a bacterial DUF199/WhiA protein: domestication of an invasive endonuclease.
Structure, 17, 2009
3HYI
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BU of 3hyi by Molmil
Crystal structure of full-length DUF199/WhiA from Thermatoga maritima
Descriptor: GLYCEROL, Protein DUF199/WhiA, SODIUM ION
Authors:Kaiser, B.K, Clifton, M.C, Shen, B.W, Stoddard, B.L.
Deposit date:2009-06-22
Release date:2009-09-01
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:The structure of a bacterial DUF199/WhiA protein: domestication of an invasive endonuclease
Structure, 17, 2009
3KO2
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BU of 3ko2 by Molmil
I-MsoI re-designed for altered DNA cleavage specificity (-7C)
Descriptor: 5'-D(*CP*GP*GP*AP*AP*CP*TP*GP*TP*CP*TP*CP*AP*CP*GP*AP*CP*GP*GP*TP*CP*TP*GP*C)-3', 5'-D(*GP*CP*AP*GP*AP*CP*CP*GP*TP*CP*GP*TP*GP*AP*GP*AP*CP*AP*GP*TP*TP*CP*CP*G)-3', CALCIUM ION, ...
Authors:Taylor, G.K, Stoddard, B.L.
Deposit date:2009-11-13
Release date:2010-05-19
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Computational reprogramming of homing endonuclease specificity at multiple adjacent base pairs.
Nucleic Acids Res., 38, 2010
3LDY
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BU of 3ldy by Molmil
An extraordinary mechanism of DNA perturbation exhibited by the rare-cutting HNH restriction endonuclease PacI
Descriptor: CALCIUM ION, DNA (5'-D(*GP*AP*GP*GP*CP*TP*TP*A)-3'), DNA (5'-D(P*AP*TP*TP*AP*AP*GP*CP*CP*TP*C)-3'), ...
Authors:Shen, B.W, Heiter, D, Chan, S.-H, Xu, S.-Y, Wilson, G, Stoddard, B.L.
Deposit date:2010-01-13
Release date:2010-04-21
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Unusual target site disruption by the rare-cutting HNH restriction endonuclease PacI.
Structure, 18, 2010
3S1S
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BU of 3s1s by Molmil
Characterization and crystal structure of the type IIG restriction endonuclease BpuSI
Descriptor: 1,2-ETHANEDIOL, IODIDE ION, MANGANESE (II) ION, ...
Authors:Shen, B.W, Xu, D, Chan, S.-H, Zheng, Y, Zhu, Y, Xu, S.-Y, Stoddard, B.L.
Deposit date:2011-05-16
Release date:2011-07-13
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Characterization and crystal structure of the type IIG restriction endonuclease RM.BpuSI.
Nucleic Acids Res., 39, 2011
3MIS
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BU of 3mis by Molmil
I-MsoI re-designed for altered DNA cleavage specificity (-8G)
Descriptor: CALCIUM ION, DNA (5'-D(*CP*GP*GP*AP*GP*CP*TP*GP*TP*CP*TP*CP*AP*CP*GP*AP*CP*GP*TP*CP*CP*TP*GP*C)-3'), DNA (5'-D(*GP*CP*AP*GP*GP*AP*CP*GP*TP*CP*GP*TP*GP*AP*GP*AP*CP*AP*GP*CP*TP*CP*CP*G)-3'), ...
Authors:Taylor, G.K, Stoddard, B.L.
Deposit date:2010-04-12
Release date:2010-05-19
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Computational reprogramming of homing endonuclease specificity at multiple adjacent base pairs.
Nucleic Acids Res., 38, 2010
3M7K
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BU of 3m7k by Molmil
Crystal structure of PacI-DNA Enzyme product complex
Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(*GP*AP*GP*GP*CP*TP*TP*AP*AP*T)-3'), DNA (5'-D(P*TP*AP*AP*GP*CP*CP*TP*C)-3'), ...
Authors:Shen, B.W, Stoddard, B.L.
Deposit date:2010-03-16
Release date:2010-04-21
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Unusual target site disruption by the rare-cutting HNH restriction endonuclease PacI.
Structure, 18, 2010
3MIP
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BU of 3mip by Molmil
I-MsoI re-designed for altered DNA cleavage specificity (-8GCG)
Descriptor: CALCIUM ION, DNA (5'-D(*CP*GP*GP*AP*GP*CP*GP*GP*TP*CP*TP*CP*AP*CP*GP*AP*CP*CP*GP*CP*CP*TP*GP*C)-3'), DNA (5'-D(*GP*CP*AP*GP*GP*CP*GP*GP*TP*CP*GP*TP*GP*AP*GP*AP*CP*CP*GP*CP*TP*CP*CP*G)-3'), ...
Authors:Taylor, G.K, Stoddard, B.L.
Deposit date:2010-04-11
Release date:2010-05-19
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Computational reprogramming of homing endonuclease specificity at multiple adjacent base pairs.
Nucleic Acids Res., 38, 2010
3UGM
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BU of 3ugm by Molmil
Structure of TAL effector PthXo1 bound to its DNA target
Descriptor: DNA-1, DNA-2, TAL effector AvrBs3/PthA
Authors:Mak, A.N.S, Bradley, P, Cernadas, R.A, Bogdanove, A.J, Stoddard, B.L.
Deposit date:2011-11-02
Release date:2012-01-04
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3 Å)
Cite:The Crystal Structure of TAL Effector PthXo1 Bound to Its DNA Target.
Science, 335, 2012
3MX1
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BU of 3mx1 by Molmil
The structure of GIY-YIG endonuclease R.Eco29kI
Descriptor: Eco29kIR
Authors:Mak, A.N.S, Lambert, A.R, Stoddard, B.L.
Deposit date:2010-05-06
Release date:2010-09-08
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Folding, DNA Recognition, and Function of GIY-YIG Endonucleases: Crystal Structures of R.Eco29kI.
Structure, 18, 2010
3MX4
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BU of 3mx4 by Molmil
DNA binding and cleavage by the GIY-YIG endonuclease R.Eco29KI inactive variant E142Q
Descriptor: DNA (5'-D(P*CP*GP*GP*GP*AP*GP*GP*CP*CP*CP*GP*CP*GP*GP*GP*CP*CP*GP*CP*CP*GP*C)-3'), DNA (5'-D(P*GP*CP*GP*GP*CP*GP*GP*CP*CP*CP*GP*CP*GP*GP*GP*CP*CP*TP*CP*CP*CP*G)-3'), Eco29kIR
Authors:Mak, A.N.S, Lambert, A.R, Stoddard, B.L.
Deposit date:2010-05-06
Release date:2010-09-08
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Folding, DNA Recognition, and Function of GIY-YIG Endonucleases: Crystal Structures of R.Eco29kI.
Structure, 18, 2010
3R3P
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BU of 3r3p by Molmil
Homing Endonuclease I-Bth0305I Catalytic Domain
Descriptor: Mobile intron protein
Authors:Taylor, G.K, Stoddard, B.L.
Deposit date:2011-03-16
Release date:2011-10-05
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Activity, specificity and structure of I-Bth0305I: a representative of a new homing endonuclease family.
Nucleic Acids Res., 39, 2011
3T1G
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BU of 3t1g by Molmil
Engineering of organophosphate hydrolase by computational design and directed evolution
Descriptor: CALCIUM ION, ZINC ION, organophosphate hydrolase
Authors:Takeuchi, R, Stoddard, B.L.
Deposit date:2011-07-21
Release date:2012-02-08
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Computational redesign of a mononuclear zinc metalloenzyme for organophosphate hydrolysis.
Nat.Chem.Biol., 8, 2012
4YIT
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BU of 4yit by Molmil
Crystal Structure of LAGLIDADG Meganuclease I-AabMI Bound to Uncleaved DNA
Descriptor: CALCIUM ION, DNA (25-MER), DNA (25MER), ...
Authors:Hallinan, J.P, Stoddard, B.L.
Deposit date:2015-03-02
Release date:2016-03-23
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.24 Å)
Cite:Indirect DNA Sequence Recognition and Its Impact on Nuclease Cleavage Activity.
Structure, 24, 2016
4YIS
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BU of 4yis by Molmil
Crystal Structure of LAGLIDADG Meganuclease I-CpaMI Bound to Uncleaved DNA
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, DNA (28-MER), ...
Authors:Hallinan, J.P, Kaiser, B.K, Stoddard, B.L.
Deposit date:2015-03-02
Release date:2016-03-23
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.89 Å)
Cite:Indirect DNA Sequence Recognition and Its Impact on Nuclease Cleavage Activity.
Structure, 24, 2016
4YHX
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BU of 4yhx by Molmil
Crystal Structure of LAGLIDADG Meganuclease I-GpeMI Bound to Uncleaved DNA
Descriptor: CALCIUM ION, DNA (27-MER), Ribosomal protein 3/homing endonuclease-like fusion protein
Authors:Hallinan, J.P, Kaiser, B.K, Stoddard, B.L.
Deposit date:2015-02-27
Release date:2016-03-09
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Indirect DNA Sequence Recognition and Its Impact on Nuclease Cleavage Activity.
Structure, 24, 2016
4Z1Z
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BU of 4z1z by Molmil
Crystal Structure of Meganuclease I-SmaMI Bound to Uncleaveable DNA with a TTCT Central Four
Descriptor: CALCIUM ION, DNA (28-MER), GLYCEROL, ...
Authors:Hallinan, J.P, Stoddard, B.L.
Deposit date:2015-03-27
Release date:2016-03-30
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Indirect DNA Sequence Recognition and Its Impact on Nuclease Cleavage Activity.
Structure, 24, 2016
4YXX
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BU of 4yxx by Molmil
Computationally designed left-handed alpha/alpha toroid with 6 repeats
Descriptor: dTor_6x35L
Authors:Doyle, L, Bolduc, J, Stoddard, B.L, Bradley, P.
Deposit date:2015-03-23
Release date:2015-12-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Rational design of alpha-helical tandem repeat proteins with closed architectures.
Nature, 528, 2015
4YXY
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BU of 4yxy by Molmil
Computationally designed left-handed alpha/alpha toroid with 9 repeats; two linked rings of 12 repeats each structure
Descriptor: dTor_9x31L
Authors:Doyle, L, Stoddard, B.L, Bradley, P.
Deposit date:2015-03-23
Release date:2015-12-16
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (3.203 Å)
Cite:Rational design of alpha-helical tandem repeat proteins with closed architectures.
Nature, 528, 2015
4Z20
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BU of 4z20 by Molmil
Crystal Structure of Meganuclease I-SmaMI Bound to Uncleaveable DNA with a TTGT Central Four
Descriptor: CALCIUM ION, DNA (26-MER), GLYCEROL, ...
Authors:Hallinan, J.P, Stoddard, B.L.
Deposit date:2015-03-27
Release date:2016-03-30
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Indirect DNA Sequence Recognition and Its Impact on Nuclease Cleavage Activity.
Structure, 24, 2016
4YY5
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BU of 4yy5 by Molmil
Computationally designed left-handed alpha/alpha toroid with 3 repeats in space group P43212
Descriptor: dTor_3x33L
Authors:Hallinan, J.P, Bradley, P, Stoddard, B.L.
Deposit date:2015-03-23
Release date:2015-12-16
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.78 Å)
Cite:Rational design of alpha-helical tandem repeat proteins with closed architectures.
Nature, 528, 2015
4YY2
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BU of 4yy2 by Molmil
Computationally designed left-handed alpha/alpha toroid with 3 repeats in space group P212121
Descriptor: SODIUM ION, dTor_3x33L
Authors:Hallinan, J.P, Bradley, P, Stoddard, B.L.
Deposit date:2015-03-23
Release date:2015-12-16
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.854 Å)
Cite:Rational design of alpha-helical tandem repeat proteins with closed architectures.
Nature, 528, 2015
4YXZ
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BU of 4yxz by Molmil
Computationally designed left-handed alpha/alpha toroid with 9 repeats
Descriptor: dTor_9x31L
Authors:Doyle, L, Stoddard, B.L, Bradley, P.
Deposit date:2015-03-23
Release date:2015-12-16
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.496 Å)
Cite:Rational design of alpha-helical tandem repeat proteins with closed architectures.
Nature, 528, 2015
4R58
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BU of 4r58 by Molmil
Crystal structure of computational designed leucine rich repeats DLRR_A in space group P21
Descriptor: Leucine Rich Repeat protein
Authors:Shen, B.W, Stoddard, B.L.
Deposit date:2014-08-20
Release date:2015-01-14
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Control of repeat-protein curvature by computational protein design.
Nat.Struct.Mol.Biol., 22, 2015

239149

数据于2025-07-23公开中

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