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9JTA
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BU of 9jta by Molmil
Crystal structure of RNF213 RING domain bound to IpaH1.4 LRR domain
Descriptor: E3 ubiquitin-protein ligase RNF213, RING-type E3 ubiquitin transferase, ZINC ION
Authors:Zhou, X.D, Wang, Y.R, Pan, L.F.
Deposit date:2024-10-03
Release date:2025-05-07
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Shigella effector IpaH1.4 subverts host E3 ligase RNF213 to evade antibacterial immunity.
Nat Commun, 16, 2025
9JW1
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BU of 9jw1 by Molmil
Cryo-EM structure of Human RNF213
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Ring finger protein 213
Authors:Zhang, H.
Deposit date:2024-10-09
Release date:2025-05-07
Method:ELECTRON MICROSCOPY (3.46 Å)
Cite:Shigella effector IpaH1.4 subverts host E3 ligase RNF213 to evade antibacterial immunity.
Nat Commun, 16, 2025
1SZJ
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BU of 1szj by Molmil
STRUCTURE OF HOLO-GLYCERALDEHYDE-3-PHOSPHATE-DEHYDROGENASE FROM PALINURUS VERSICOLOR REFINED 2.0 ANGSTROM RESOLUTION
Descriptor: D-GLYCERALDEHYDE-3-PHOSPHATE-DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION
Authors:Song, S, Li, J, Lin, Z.
Deposit date:1997-02-04
Release date:1998-09-16
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Preliminary crystallographic studies of lobster D-glyceraldehyde-3-phosphate dehydrogenase and the modified enzyme carrying the fluorescent derivative.
J.Mol.Biol., 171, 1983
4WXM
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BU of 4wxm by Molmil
FleQ REC domain from Pseudomonas aeruginosa PAO1
Descriptor: Transcriptional regulator FleQ
Authors:Su, T, Liu, S, Gu, L.
Deposit date:2014-11-14
Release date:2015-09-23
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The REC domain mediated dimerization is critical for FleQ from Pseudomonas aeruginosa to function as a c-di-GMP receptor and flagella gene regulator
J.Struct.Biol., 192, 2015
9BCE
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BU of 9bce by Molmil
Shewanella oneidensis LysR family regulator SO0839 regulatory domain
Descriptor: Transcriptional regulator LysR family
Authors:Han, S.R, Liang, H.H, Lin, Z.H, Fan, Y.L, Ye, K, Gao, H.G, Tao, Y.J, Jin, M.
Deposit date:2024-04-08
Release date:2024-11-20
Last modified:2024-12-11
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:A bacterial transcription activator dedicated to the expression of the enzyme catalyzing the first committed step in fatty acid biosynthesis.
Nucleic Acids Res., 52, 2024
5YJH
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BU of 5yjh by Molmil
Structural insights into periostin functions
Descriptor: CALCIUM ION, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Liu, H, Liu, J, Xu, F.
Deposit date:2017-10-10
Release date:2018-05-23
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.957 Å)
Cite:Structural characterizations of human periostin dimerization and cysteinylation.
FEBS Lett., 592, 2018
5YJG
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BU of 5yjg by Molmil
Structural insights into periostin functions
Descriptor: CALCIUM ION, CHLORIDE ION, CYSTEINE, ...
Authors:Liu, H, Liu, J, Xu, F.
Deposit date:2017-10-10
Release date:2018-05-23
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.399 Å)
Cite:Structural characterizations of human periostin dimerization and cysteinylation.
FEBS Lett., 592, 2018
4KNG
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BU of 4kng by Molmil
Crystal structure of human LGR5-RSPO1-RNF43
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, E3 ubiquitin-protein ligase RNF43, Leucine-rich repeat-containing G-protein coupled receptor 5, ...
Authors:Chen, P.H, He, X.
Deposit date:2013-05-09
Release date:2013-06-19
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The structural basis of R-spondin recognition by LGR5 and RNF43.
Genes Dev., 27, 2013
9BVP
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BU of 9bvp by Molmil
Vitamin K-dependent gamma-carboxylase with TMG2 propeptide and glutamate-rich region and with vitamin K hydroquinone
Descriptor: (4S,7R)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Li, W, Liu, B, Cao, Q.
Deposit date:2024-05-20
Release date:2025-01-22
Last modified:2025-03-26
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Molecular basis of vitamin-K-driven gamma-carboxylation at the membrane interface.
Nature, 639, 2025
9BVO
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BU of 9bvo by Molmil
Vitamin K-dependent gamma-carboxylase in apo state
Descriptor: (4S,7R)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Li, W, Liu, B, Cao, Q.
Deposit date:2024-05-20
Release date:2025-01-22
Last modified:2025-03-26
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Molecular basis of vitamin-K-driven gamma-carboxylation at the membrane interface.
Nature, 639, 2025
9BVL
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BU of 9bvl by Molmil
Vitamin K-dependent gamma-carboxylase with factor X propeptide and glutamate-rich region and with vitamin K hydroquinone
Descriptor: (4S,7R)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Li, W, Liu, B, Cao, Q.
Deposit date:2024-05-20
Release date:2025-01-22
Last modified:2025-03-26
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Molecular basis of vitamin-K-driven gamma-carboxylation at the membrane interface.
Nature, 639, 2025
9BVR
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BU of 9bvr by Molmil
Vitamin K-dependent gamma-carboxylase with factor IX propeptide and partially carboxylated glutamate-rich region and with vitamin K hydroquinone and calcium
Descriptor: (4S,7R)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Li, W, Liu, B, Cao, Q.
Deposit date:2024-05-20
Release date:2025-01-22
Last modified:2025-03-26
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Molecular basis of vitamin-K-driven gamma-carboxylation at the membrane interface.
Nature, 639, 2025
9BVQ
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BU of 9bvq by Molmil
Vitamin K-dependent gamma-carboxylase with TMG2 propeptide and glutamate-rich region
Descriptor: (4S,7R)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Li, W, Liu, B, Cao, Q.
Deposit date:2024-05-20
Release date:2025-01-22
Last modified:2025-03-26
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Molecular basis of vitamin-K-driven gamma-carboxylation at the membrane interface.
Nature, 639, 2025
9BVK
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BU of 9bvk by Molmil
Vitamin K-dependent gamma-carboxylase with factor IX propeptide and glutamate-rich region and with vitamin K hydroquinone
Descriptor: (4S,7R)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Li, W, Liu, B, Cao, Q.
Deposit date:2024-05-20
Release date:2025-01-22
Last modified:2025-03-26
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Molecular basis of vitamin-K-driven gamma-carboxylation at the membrane interface.
Nature, 639, 2025
9BVM
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BU of 9bvm by Molmil
Vitamin K-dependent gamma-carboxylase with protein C propeptide and glutamate-rich region and with vitamin K hydroquinone
Descriptor: (4S,7R)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Li, W, Liu, B, Cao, Q.
Deposit date:2024-05-20
Release date:2025-01-22
Last modified:2025-03-26
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Molecular basis of vitamin-K-driven gamma-carboxylation at the membrane interface.
Nature, 639, 2025
4KVN
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BU of 4kvn by Molmil
Crystal structure of Fab 39.29 in complex with Influenza Hemagglutinin A/Perth/16/2009 (H3N2)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
Authors:Fong, R, Swem, L.R, Lupardus, P.J.
Deposit date:2013-05-22
Release date:2013-08-07
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:A Novel In vivo Human Plasmablast Enrichment Technique Allows Rapid Identification of Therapeutic Anti-Influenza A Antibodies
Cell Host Microbe, 14, 2013
5K7K
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BU of 5k7k by Molmil
Design and Optimization of Biaryl Ether Aryl Sulfonamides as Selective Inhibitors of NaV1.7: Discovery of Clinical Candidate PF-05089771
Descriptor: 4-[4-chloranyl-2-(1~{H}-pyrazol-4-yl)phenoxy]-3-cyano-~{N}-(1,3-thiazol-2-yl)benzenesulfonamide, Cytochrome P450 2C9, PROTOPORPHYRIN IX CONTAINING FE
Authors:Swain, N, Chrencik, J.
Deposit date:2016-05-26
Release date:2017-06-07
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Discovery of Clinical Candidate 4-[2-(5-Amino-1H-pyrazol-4-yl)-4-chlorophenoxy]-5-chloro-2-fluoro-N-1,3-thiazol-4-ylbenzenesulfonamide (PF-05089771): Design and Optimization of Diaryl Ether Aryl Sulfonamides as Selective Inhibitors of NaV1.7.
J. Med. Chem., 60, 2017
7Y8Y
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BU of 7y8y by Molmil
Structure of Cas7-11-crRNA-tgRNA in complex with TPR-CHAT
Descriptor: CHAT domain protein, RAMP superfamily protein, RNA (37-MER), ...
Authors:Wang, S, Guo, M, Zhu, Y, Huang, Z.
Deposit date:2022-06-24
Release date:2023-06-28
Last modified:2024-01-10
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Cryo-EM structure of the type III-E CRISPR-Cas effector gRAMP in complex with TPR-CHAT.
Cell Res., 32, 2022
7XSC
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BU of 7xsc by Molmil
Crystal structure of SARS-CoV-2 spike receptor binding domain bound with P5S-2B10
Descriptor: P5S-2B10 Heavy chain, P5S-2B10 Light chain, Spike protein S1
Authors:Wang, X, Wang, Z, Lin, Z.
Deposit date:2022-05-13
Release date:2023-05-24
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.88 Å)
Cite:Infection with wild-type SARS-CoV-2 elicits broadly neutralizing and protective antibodies against omicron subvariants.
Nat.Immunol., 24, 2023
5JJU
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BU of 5jju by Molmil
Crystal structure of Rv2837c complexed with 5'-pApA and 5'-AMP
Descriptor: ADENOSINE MONOPHOSPHATE, MANGANESE (II) ION, RNA (5'-R(P*AP*A)-3'), ...
Authors:Wang, F, He, Q, Liu, S, Gu, L.
Deposit date:2016-04-25
Release date:2016-05-04
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.312 Å)
Cite:Structural and biochemical insight into the mechanism of Rv2837c from Mycobacterium tuberculosis as a c-di-NMP phosphodiesterase
J.Biol.Chem., 291, 2016
1B4W
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BU of 1b4w by Molmil
BASIC PHOSPHOLIPASE A2 FROM AGKISTRODON HALYS PALLAS-IMPLICATIONS FOR ITS ASSOCIATION AND ANTICOAGULANT ACTIVITIES BY X-RAY CRYSTALLOGRAPHY
Descriptor: PROTEIN (PHOSPHOLIPASE A2), octyl beta-D-glucopyranoside
Authors:Zhao, K.H, Lin, Z.J.
Deposit date:1998-12-30
Release date:2000-01-12
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of basic phospholipase A2 from Agkistrodon halys Pallas: implications for its association, hemolytic and anticoagulant activities.
Toxicon, 38, 2000
6LPV
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BU of 6lpv by Molmil
structure of Spermidine hydroxycinnamoyl transferases from Arabidopsis thaliana
Descriptor: COENZYME A, SPERMIDINE, Spermidine hydroxycinnamoyl transferase
Authors:Wang, C.Y, Zhang, P.
Deposit date:2020-01-12
Release date:2021-01-13
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.297 Å)
Cite:Structural and Biochemical Insights Into Two BAHD Acyltransferases ( At SHT and At SDT) Involved in Phenolamide Biosynthesis.
Front Plant Sci, 11, 2020
1A2A
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BU of 1a2a by Molmil
AGKISTROTOXIN, A PHOSPHOLIPASE A2-TYPE PRESYNAPTIC NEUROTOXIN FROM AGKISTRODON HALYS PALLAS
Descriptor: CHLORIDE ION, PHOSPHOLIPASE A2
Authors:Tang, L, Zhou, Y, Lin, Z.
Deposit date:1997-12-25
Release date:1999-01-13
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of agkistrodotoxin, a phospholipase A2-type presynaptic neurotoxin from agkistrodon halys pallas.
J.Mol.Biol., 282, 1998
4ZRI
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BU of 4zri by Molmil
Crystal structure of Merlin-FERM and Lats2
Descriptor: Merlin, Serine/threonine-protein kinase LATS2
Authors:Li, F, Zhou, H, Long, J, Shen, Y.
Deposit date:2015-05-12
Release date:2015-06-17
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Angiomotin binding-induced activation of Merlin/NF2 in the Hippo pathway
Cell Res., 25, 2015
6O6W
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BU of 6o6w by Molmil
Solution structure of human myeloid-derived growth factor
Descriptor: Myeloid-derived growth factor
Authors:Bortnov, V, Tonelli, M, Lee, W, Markley, J.L, Mosher, D.F.
Deposit date:2019-03-07
Release date:2019-11-13
Last modified:2024-11-20
Method:SOLUTION NMR
Cite:Solution structure of human myeloid-derived growth factor suggests a conserved function in the endoplasmic reticulum.
Nat Commun, 10, 2019

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数据于2025-07-23公开中

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