4KNG
Crystal structure of human LGR5-RSPO1-RNF43
Summary for 4KNG
Entry DOI | 10.2210/pdb4kng/pdb |
Descriptor | Leucine-rich repeat-containing G-protein coupled receptor 5, R-spondin-1, E3 ubiquitin-protein ligase RNF43, ... (6 entities in total) |
Functional Keywords | leucine-rich repeat, cysteine-rich domain, furin-repeat, protease-associated domain, ligand recognition, protein-protein interaction, n-linked glycosylation, membrane protein, signaling protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 6 |
Total formula weight | 178882.88 |
Authors | Chen, P.H.,He, X. (deposition date: 2013-05-09, release date: 2013-06-19, Last modification date: 2020-07-29) |
Primary citation | Chen, P.H.,Chen, X.,Lin, Z.,Fang, D.,He, X. The structural basis of R-spondin recognition by LGR5 and RNF43. Genes Dev., 27:1345-1350, 2013 Cited by PubMed: 23756651DOI: 10.1101/gad.219915.113 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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