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4YS0
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BU of 4ys0 by Molmil
Conformational changes of the clamp of the protein translocation ATPase SecA from Thermotoga maritima
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Protein translocase subunit SecA
Authors:Chen, Y, Rapoport, T.A.
Deposit date:2015-03-16
Release date:2015-06-03
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.897 Å)
Cite:Conformational Changes of the Clamp of the Protein Translocation ATPase SecA.
J.Mol.Biol., 427, 2015
4YPT
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BU of 4ypt by Molmil
X-ray structural of three tandemly linked domains of nsp3 from murine hepatitis virus at 2.60 Angstroms resolution
Descriptor: GLYCEROL, Replicase polyprotein 1ab, ZINC ION
Authors:Chen, Y, Savinov, S.N, Mielech, A.M, Cao, T, Baker, S.C, Mesecar, A.D.
Deposit date:2015-03-13
Release date:2015-08-26
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.6009 Å)
Cite:X-ray Structural and Functional Studies of the Three Tandemly Linked Domains of Non-structural Protein 3 (nsp3) from Murine Hepatitis Virus Reveal Conserved Functions.
J.Biol.Chem., 290, 2015
3BU8
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BU of 3bu8 by Molmil
Crystal Structure of TRF2 TRFH domain and TIN2 peptide complex
Descriptor: TERF1-interacting nuclear factor 2, Telomeric repeat-binding factor 2
Authors:Chen, Y, Yang, Y, van Overbeek, M, Donigian, J.R, Baciu, P, de Lange, T, Lei, M.
Deposit date:2008-01-02
Release date:2008-02-19
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:A shared docking motif in TRF1 and TRF2 used for differential recruitment of telomeric proteins.
Science, 319, 2008
3BUA
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BU of 3bua by Molmil
Crystal Structure of TRF2 TRFH domain and APOLLO peptide complex
Descriptor: DNA cross-link repair 1B protein, Telomeric repeat-binding factor 2
Authors:Chen, Y, Yang, Y, van Overbeek, M, Donigian, J.R, Baciu, P, de Lange, T, Lei, M.
Deposit date:2008-01-02
Release date:2008-02-19
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A shared docking motif in TRF1 and TRF2 used for differential recruitment of telomeric proteins.
Science, 319, 2008
4CS6
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BU of 4cs6 by Molmil
Crystal structure of AadA - an aminoglycoside adenyltransferase
Descriptor: AMINOGLYCOSIDE ADENYLTRANSFERASE
Authors:Chen, Y, Nasvall, J, Andersson, D.I, Selmer, M.
Deposit date:2014-03-05
Release date:2015-03-25
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.502 Å)
Cite:Structure of Aada from Salmonella Enterica: A Monomeric Aminoglycoside (3'')(9) Adenyltransferase.
Acta Crystallogr.,Sect.D, 71, 2015
3BQO
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BU of 3bqo by Molmil
Crystal Structure of TRF1 TRFH domain and TIN2 peptide complex
Descriptor: TERF1-interacting nuclear factor 2, Telomeric repeat-binding factor 1
Authors:Chen, Y, Yang, Y, van Overbeek, M, Donigian, J.R, Baciu, P, de Lange, T, Lei, M.
Deposit date:2007-12-20
Release date:2008-02-19
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:A shared docking motif in TRF1 and TRF2 used for differential recruitment of telomeric proteins.
Science, 319, 2008
3TOJ
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BU of 3toj by Molmil
Structure of the SPRY domain of human Ash2L
Descriptor: Set1/Ash2 histone methyltransferase complex subunit ASH2
Authors:Chen, Y, Cao, F, Wan, B, Dou, Y, Lei, M.
Deposit date:2011-09-05
Release date:2012-01-25
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Structure of the SPRY domain of human Ash2L and its interactions with RbBP5 and DPY30.
Cell Res., 22, 2012
1J48
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BU of 1j48 by Molmil
Crystal Structure of Apo-C1027
Descriptor: Apoprotein of C1027
Authors:Chen, Y, Li, J, Liu, Y, Bartlam, M, Gao, Y, Jin, L, Tang, H, Shao, Y, Zhen, Y, Rao, Z.
Deposit date:2001-07-30
Release date:2003-06-03
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of Apo-C1027 and Computer Modeling Analysis of C1027 Chromophore- Protein Complex
To be published
5E9T
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BU of 5e9t by Molmil
Crystal structure of GtfA/B complex
Descriptor: Glycosyltransferase Gtf1, Glycosyltransferase-stabilizing protein Gtf2, MAGNESIUM ION
Authors:Chen, Y, Rapoport, T.A.
Deposit date:2015-10-15
Release date:2016-03-02
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.92 Å)
Cite:Mechanism of a cytosolic O-glycosyltransferase essential for the synthesis of a bacterial adhesion protein.
Proc.Natl.Acad.Sci.USA, 113, 2016
4ZMU
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BU of 4zmu by Molmil
Dcsbis, a diguanylate cyclase from Pseudomonas aeruginosa
Descriptor: diguanylate cyclase
Authors:Chen, Y, Liu, C, Liu, S, Chi, K, Gu, L.
Deposit date:2015-05-04
Release date:2016-05-04
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.502 Å)
Cite:crystal structure of Dcsbis from Pseudomonas aeruginosa
To Be Published
4ZMM
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BU of 4zmm by Molmil
GGDEF domain of Dcsbis complexed with c-di-GMP
Descriptor: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), diguanylate cyclase
Authors:Chen, Y, Liu, C, Liu, S, Chi, K, Gu, L.
Deposit date:2015-05-04
Release date:2016-05-04
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.503 Å)
Cite:Crystal structure of Dcsbis GGDEF domain complexed with c-di-GMP
To Be Published
5FX8
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BU of 5fx8 by Molmil
Complete structure of manganese lipoxygenase of Gaeumannomyces graminis and partial structure of zonadhesin of Komagataella pastoris
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Chen, Y, Wennman, A, Karkehanadi, S, Engstrom, A, Oliw, E.H.
Deposit date:2016-02-25
Release date:2016-06-22
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structure of Linoleate 13R-Manganese Lipoxygenase and an Adhesion Protein
J.Lipid Res., 57, 2016
4L3N
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BU of 4l3n by Molmil
Crystal structure of the receptor-binding domain from newly emerged Middle East respiratory syndrome coronavirus
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S protein
Authors:Chen, Y, Rajashankar, K.R, Yang, Y, Agnihothram, S.S, Liu, C, Lin, Y.-L, Baric, R.S, Li, F.
Deposit date:2013-06-06
Release date:2013-07-31
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Crystal structure of the receptor-binding domain from newly emerged middle East respiratory syndrome coronavirus.
J.Virol., 87, 2013
3PUN
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BU of 3pun by Molmil
Crystal structure of P domain dimer of Norovirus VA207 with Lewis y tetrasaccharide
Descriptor: Capsid, alpha-L-fucopyranose-(1-2)-beta-D-galactopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]2-acetamido-2-deoxy-alpha-D-glucopyranose
Authors:Chen, Y, Tan, M, Xia, M, Hao, N, Zhang, X.C, Huang, P, Jiang, X, Li, X, Rao, Z.
Deposit date:2010-12-06
Release date:2011-08-03
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystallography of a Lewis-binding norovirus, elucidation of strain-specificity to the polymorphic human histo-blood group antigens
Plos Pathog., 7, 2011
6ALJ
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BU of 6alj by Molmil
ALDH1A2 liganded with NAD and compound WIN18,446
Descriptor: Aldehyde dehydrogenase 1A2, N,N'-(octane-1,8-diyl)bis(2,2-dichloroacetamide), NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Chen, Y, Zhu, J.-Y, Schonbrunn, E.
Deposit date:2017-08-08
Release date:2018-01-10
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Structural Basis of ALDH1A2 Inhibition by Irreversible and Reversible Small Molecule Inhibitors.
ACS Chem. Biol., 13, 2018
6B5H
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BU of 6b5h by Molmil
ALDH1A2 liganded with NAD and 1-(4-cyanophenyl)-N-(3-fluorophenyl)-3-[4-(methylsulfonyl)phenyl]-1H-pyrazole-4-carboxamide (compound CM121)
Descriptor: 1-(4-cyanophenyl)-N-(3-fluorophenyl)-3-[4-(methylsulfonyl)phenyl]-1H-pyrazole-4-carboxamide, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Retinal dehydrogenase 2
Authors:Chen, Y, Zhu, J.-Y, Schonbrunn, E.
Deposit date:2017-09-29
Release date:2018-01-10
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Basis of ALDH1A2 Inhibition by Irreversible and Reversible Small Molecule Inhibitors.
ACS Chem. Biol., 13, 2018
6B5G
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BU of 6b5g by Molmil
ALDH1A2 liganded with NAD and (3-ethoxythiophen-2-yl){4-[4-nitro-3-(pyrrolidin-1-yl)phenyl]piperazin-1-yl}methanone (compound 6-118)
Descriptor: (3-ethoxythiophen-2-yl){4-[4-nitro-3-(pyrrolidin-1-yl)phenyl]piperazin-1-yl}methanone, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Retinal dehydrogenase 2
Authors:Chen, Y, Zhu, J.-Y, Schonbrunn, E.
Deposit date:2017-09-29
Release date:2018-01-10
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Basis of ALDH1A2 Inhibition by Irreversible and Reversible Small Molecule Inhibitors.
ACS Chem. Biol., 13, 2018
6B5I
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BU of 6b5i by Molmil
ALDH1A2 liganded with 1-(4-cyanophenyl)-N-(3-fluorophenyl)-3-[4-(methylsulfonyl)phenyl]-1H-pyrazole-4-carboxamide (compound CM121)
Descriptor: 1-(4-cyanophenyl)-N-(3-fluorophenyl)-3-[4-(methylsulfonyl)phenyl]-1H-pyrazole-4-carboxamide, Retinal dehydrogenase 2
Authors:Chen, Y, Zhu, J.-Y, Schonbrunn, E.
Deposit date:2017-09-29
Release date:2018-01-10
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Basis of ALDH1A2 Inhibition by Irreversible and Reversible Small Molecule Inhibitors.
ACS Chem. Biol., 13, 2018
1ZBH
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BU of 1zbh by Molmil
3'-end specific recognition of histone mRNA stem-loop by 3'-exonuclease
Descriptor: 3'-5' exonuclease ERI1, 5'-R(*CP*CP*GP*GP*CP*UP*CP*UP*UP*UP*UP*CP*AP*GP*AP*GP*CP*CP*GP*G)-3', ADENOSINE MONOPHOSPHATE, ...
Authors:Cheng, Y, Patel, D.J.
Deposit date:2005-04-08
Release date:2006-09-26
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis for 3'-end specific recognition of histone mRNA stem-loop by 3'-exonuclease, a human nuclease that also targets siRNA
To be Published
5E9U
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BU of 5e9u by Molmil
Crystal structure of GtfA/B complex bound to UDP and GlcNAc
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Glycosyltransferase Gtf1, Glycosyltransferase-stabilizing protein Gtf2, ...
Authors:Chen, Y, Rapoport, T.A.
Deposit date:2015-10-15
Release date:2016-03-02
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (3.84 Å)
Cite:Mechanism of a cytosolic O-glycosyltransferase essential for the synthesis of a bacterial adhesion protein.
Proc.Natl.Acad.Sci.USA, 113, 2016
1ZBU
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BU of 1zbu by Molmil
crystal structure of full-length 3'-exonuclease
Descriptor: 3'-5' exonuclease ERI1, ADENOSINE MONOPHOSPHATE, MAGNESIUM ION
Authors:Cheng, Y, Patel, D.J.
Deposit date:2005-04-08
Release date:2006-09-19
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.998 Å)
Cite:Structural basis for 3'-end specific recognition of histone mRNA stem-loop by 3'-exonuclease, a human nuclease that also targets siRNA
To be Published
3M9E
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BU of 3m9e by Molmil
Thyroid hormone beta DNA binding domain homodimer with inverted palindrome TRE
Descriptor: DNA (5'-D(*AP*TP*TP*GP*AP*CP*CP*TP*CP*AP*GP*CP*TP*GP*AP*GP*GP*TP*CP*AP*AP*T)-3'), Thyroid hormone receptor beta, ZINC ION
Authors:Chen, Y.
Deposit date:2010-03-22
Release date:2010-08-18
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.406 Å)
Cite:Structure of a thyroid hormone receptor DNA-binding domain homodimer bound to an inverted palindrome DNA response element.
Mol.Endocrinol., 24, 2010
1JE9
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BU of 1je9 by Molmil
NMR SOLUTION STRUCTURE OF NT2
Descriptor: SHORT NEUROTOXIN II
Authors:Cheng, Y, Wang, W, Wang, J.
Deposit date:2001-06-16
Release date:2001-07-04
Last modified:2024-10-23
Method:SOLUTION NMR
Cite:Structure-function relationship of three neurotoxins from the venom of Naja kaouthia: a comparison between the NMR-derived structure of NT2 with its homologues, NT1 and NT3
BIOCHIM.BIOPHYS.ACTA, 1594, 2002
5X8F
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BU of 5x8f by Molmil
Ternary complex structure of a double mutant I454RA456K of o-Succinylbenzoate CoA Synthetase (MenE) from Bacillus Subtilis bound with AMP and its product analogue OSB-NCoA at 1.76 angstrom
Descriptor: 2-succinylbenzoate--CoA ligase, ADENOSINE MONOPHOSPHATE, CALCIUM ION, ...
Authors:Chen, Y, Guo, Z.
Deposit date:2017-03-02
Release date:2017-06-07
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.763 Å)
Cite:Crystal structure of the thioesterification conformation of Bacillus subtilis o-succinylbenzoyl-CoA synthetase reveals a distinct substrate-binding mode
J. Biol. Chem., 292, 2017
5X8G
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BU of 5x8g by Molmil
Binary complex structure of a double mutant I454RA456K of o-Succinylbenzoate CoA Synthetase (MenE) from Bacillus Subtilis bound with its product analogue OSB-NCoA at 1.90 angstrom
Descriptor: 2-succinylbenzoate--CoA ligase, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Chen, Y, Guo, Z.
Deposit date:2017-03-02
Release date:2017-06-07
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of the thioesterification conformation of Bacillus subtilis o-succinylbenzoyl-CoA synthetase reveals a distinct substrate-binding mode
J. Biol. Chem., 292, 2017

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数据于2024-11-13公开中

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