1LU2
 
 | | DOLICHOS BIFLORUS SEED LECTIN IN COMPLEX WITH THE BLOOD GROUP A TRISACCHARIDE | | Descriptor: | 2-acetamido-2-deoxy-alpha-D-galactopyranose, CALCIUM ION, LECTIN, ... | | Authors: | Hamelryck, T.W, Loris, R, Bouckaert, J, Strecker, G, Imberty, A, Fernandez, E, Wyns, L, Etzler, M.E. | | Deposit date: | 1998-07-30 | | Release date: | 1998-12-09 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Carbohydrate binding, quaternary structure and a novel hydrophobic binding site in two legume lectin oligomers from Dolichos biflorus.
J.Mol.Biol., 286, 1999
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1LJL
 | | Wild Type pI258 S. aureus arsenate reductase | | Descriptor: | POTASSIUM ION, arsenate reductase | | Authors: | Messens, J, Martins, J.C, Van Belle, K, Brosens, E, Desmyter, A, De Gieter, M, Wieruszeski, J.M, Willem, R, Wyns, L, Zegers, I. | | Deposit date: | 2002-04-21 | | Release date: | 2002-08-07 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.01 Å) | | Cite: | All intermediates of the arsenate reductase mechanism, including an intramolecular dynamic disulfide cascade.
Proc.Natl.Acad.Sci.USA, 99, 2002
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1LU1
 | | THE STRUCTURE OF THE DOLICHOS BIFLORUS SEED LECTIN IN COMPLEX WITH THE FORSSMAN DISACCHARIDE | | Descriptor: | 2-acetamido-2-deoxy-alpha-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose, ADENINE, CALCIUM ION, ... | | Authors: | Hamelryck, T.W, Loris, R, Bouckaert, J, Strecker, G, Imberty, A, Fernandez, E, Wyns, L, Etzler, M.E. | | Deposit date: | 1998-07-24 | | Release date: | 1998-12-09 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Carbohydrate binding, quaternary structure and a novel hydrophobic binding site in two legume lectin oligomers from Dolichos biflorus.
J.Mol.Biol., 286, 1999
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1LJU
 | | X-RAY STRUCTURE OF C15A ARSENATE REDUCTASE FROM PI258 COMPLEXED WITH ARSENITE | | Descriptor: | POTASSIUM ION, arsenate reductase | | Authors: | Zegers, I, Martins, J.C, Willem, R, Wyns, L, Messens, J. | | Deposit date: | 2002-04-22 | | Release date: | 2002-08-07 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | All intermediates of the arsenate reductase mechanism, including an intramolecular dynamic disulfide cascade.
Proc.Natl.Acad.Sci.USA, 99, 2002
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1XFP
 | | Crystal structure of the CDR2 germline reversion mutant of cAb-Lys3 in complex with hen egg white lysozyme | | Descriptor: | FORMIC ACID, Lysozyme C, heavy chain antibody | | Authors: | De Genst, E, Handelberg, F, Van Meirhaeghe, A, Vynck, S, Loris, R, Wyns, L, Muyldermans, S. | | Deposit date: | 2004-09-15 | | Release date: | 2004-09-28 | | Last modified: | 2013-02-06 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Chemical Basis for the Affinity Maturation of a Camel Single Domain Antibody
J.Biol.Chem., 279, 2004
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1YC8
 | | cAbAn33- Y37V/E44G/R45L triple mutant | | Descriptor: | anti-VSG immunoglobulin heavy chain variable domain cAbAn33 | | Authors: | Conrath, K, Vincke, C, Stijlemans, B, Schymkowitz, J, Wyns, L, Muyldermans, S, Loris, R. | | Deposit date: | 2004-12-22 | | Release date: | 2005-06-14 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Antigen Binding and Solubility Effects upon the Veneering of a Camel VHH in Framework-2 to Mimic a VH.
J.Mol.Biol., 350, 2005
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1YC7
 | | cAbAn33 VHH fragment against VSG | | Descriptor: | SULFATE ION, anti-VSG immunoglobulin heavy chain variable domain cAbAn33 | | Authors: | Conrath, K, Vincke, C, Stijlemans, B, Schymkowitz, J, Wyns, L, Muyldermans, S, Loris, R. | | Deposit date: | 2004-12-22 | | Release date: | 2005-06-14 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Antigen Binding and Solubility Effects upon the Veneering of a Camel VHH in Framework-2 to Mimic a VH.
J.Mol.Biol., 350, 2005
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1ZMY
 | | cAbBCII-10 VHH framework with CDR loops of cAbLys3 grafted on it and in complex with hen egg white lysozyme | | Descriptor: | Antibody cabbcII-10:lys3, Lysozyme C | | Authors: | Saerens, D, Pellis, M, Loris, R, Pardon, E, Dumoulin, M, Matagne, A, Wyns, L, Muyldermans, S, Conrath, K. | | Deposit date: | 2005-05-11 | | Release date: | 2005-10-04 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Identification of a universal VHH framework to graft non-canonical antigen-binding loops of camel single-domain antibodies
J.Mol.Biol., 352, 2005
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1YVS
 | | Trimeric domain swapped barnase | | Descriptor: | BARNASE, SULFATE ION | | Authors: | Zegers, I, Wyns, L. | | Deposit date: | 1998-12-10 | | Release date: | 1999-02-02 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Trimeric domain-swapped barnase.
Proc.Natl.Acad.Sci.USA, 96, 1999
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1ZVH
 | | Crystal structure of the VHH domain D2-L24 in complex with hen egg white lysozyme | | Descriptor: | Immunoglobulin heavy chain antibody variable domain, Lysozyme C | | Authors: | De Genst, E, Silence, K, Decanniere, K, Conrath, K, Loris, R, Kinne, J, Muyldermans, S, Wyns, L. | | Deposit date: | 2005-06-02 | | Release date: | 2006-04-04 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Molecular basis for the preferential cleft recognition by dromedary heavy-chain antibodies.
Proc.Natl.Acad.Sci.Usa, 103, 2006
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1ZV5
 | | Crystal structure of the variable domain of the camelid heavy-chain antibody D2-L29 in complex with hen egg white lysozyme | | Descriptor: | Lysozyme C, PHOSPHATE ION, immunoglobulin heavy chain antibody variable domain | | Authors: | De Genst, E, Silence, K, Decanniere, K, Conrath, K, Loris, R, Kinne, J, Muyldermans, S, Wyns, L. | | Deposit date: | 2005-06-01 | | Release date: | 2006-04-04 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Molecular basis for the preferential cleft recognition by dromedary heavy-chain antibodies.
Proc.Natl.Acad.Sci.Usa, 103, 2006
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1ZVY
 | | Crystal structure of the VHH D3-L11 in complex with hen egg white lysozyme | | Descriptor: | GLYCEROL, Immunoglobulin heavy chain antibody variable domain, Lysozyme C, ... | | Authors: | De Genst, E, Silence, K, Decanniere, K, Conrath, K, Loris, R, Kinne, J, Muyldermans, S, Wyns, L. | | Deposit date: | 2005-06-03 | | Release date: | 2006-04-04 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (1.63 Å) | | Cite: | Molecular basis for the preferential cleft recognition by dromedary heavy-chain antibodies.
Proc.Natl.Acad.Sci.Usa, 103, 2006
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1N3P
 | | Pterocarpus angolensis lectin in complex with sucrose | | Descriptor: | CALCIUM ION, MANGANESE (II) ION, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose, ... | | Authors: | Loris, R, Imberty, A, Beeckmans, S, Van Driessche, E, Read, J.S, Bouckaert, J, De Greve, H, Buts, L, Wyns, L. | | Deposit date: | 2002-10-29 | | Release date: | 2002-11-20 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal structure of Pterocarpus angolensis lectin in complex with glucose, sucrose, and turanose
J.BIOL.CHEM., 278, 2003
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1N3O
 | | Pterocarcpus angolensis lectin in complex with alpha-methyl glucose | | Descriptor: | CALCIUM ION, MANGANESE (II) ION, lectin PAL, ... | | Authors: | Loris, R, Imberty, A, Beeckmans, S, Van Driessche, E, Read, J.S, Bouckaert, J, De Greve, H, Buts, L, Wyns, L. | | Deposit date: | 2002-10-29 | | Release date: | 2002-11-20 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structure of Pterocarpus angolensis lectin in complex with glucose, sucrose, and turanose
J.BIOL.CHEM., 278, 2003
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1N3Q
 | | Pterocarpus angolensis lectin complexed with turanose | | Descriptor: | CALCIUM ION, MANGANESE (II) ION, alpha-D-glucopyranose-(1-3)-beta-D-fructofuranose, ... | | Authors: | Loris, R, Imberty, A, Beeckmans, S, Van Driessche, E, Read, J.S, Bouckaert, J, De Greve, H, Buts, L, Wyns, L. | | Deposit date: | 2002-10-29 | | Release date: | 2002-11-20 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal structure of Pterocarpus angolensis lectin in complex with glucose, sucrose, and turanose
J.BIOL.CHEM., 278, 2003
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1RXE
 | | ArsC complexed with MNB | | Descriptor: | 5-MERCAPTO-2-NITRO-BENZOIC ACID, Arsenate reductase, PERCHLORATE ION, ... | | Authors: | Messens, J, Van Molle, I, Vanhaesebrouck, P, Limbourg, M, Van Belle, K, Wahni, K, Martins, J.C, Loris, R, Wyns, L. | | Deposit date: | 2003-12-18 | | Release date: | 2004-06-01 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | The structure of a triple mutant of pI258 arsenate reductase from Staphylococcus aureus and its 5-thio-2-nitrobenzoic acid adduct.
Acta Crystallogr.,Sect.D, 60, 2004
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1RRA
 | | RIBONUCLEASE A FROM RATTUS NORVEGICUS (COMMON RAT) | | Descriptor: | PHOSPHATE ION, PROTEIN (RIBONUCLEASE) | | Authors: | Gupta, V, Muyldermans, S, Wyns, L, Salunke, D. | | Deposit date: | 1998-12-04 | | Release date: | 1998-12-09 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | The crystal structure of recombinant rat pancreatic RNase A.
Proteins, 35, 1999
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1RJC
 | | Crystal structure of the camelid single domain antibody cAb-Lys2 in complex with hen egg white lysozyme | | Descriptor: | GLYCEROL, Lysozyme C, PHOSPHATE ION, ... | | Authors: | De Genst, E, Silence, K, Ghahroudi, M.A, Decanniere, K, Loris, R, Kinne, J, Wyns, L, Muyldermans, S. | | Deposit date: | 2003-11-19 | | Release date: | 2005-02-01 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Strong in vivo maturation compensates for structurally restricted H3 loops in antibody repertoires.
J.Biol.Chem., 280, 2005
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1UKG
 | | Pterocarps angolensis lectin PAL in complex with methyl-alpha-mannose | | Descriptor: | CALCIUM ION, MANGANESE (II) ION, lectin, ... | | Authors: | Loris, R, Van Walle, I, De Greve, H, Beeckmans, S, Deboeck, F, Wyns, L, Bouckaert, J. | | Deposit date: | 2003-08-21 | | Release date: | 2004-02-10 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structural Basis of Oligomannose Recognition by the Pterocarpus angolensis Seed Lectin
J.Mol.Biol., 335, 2004
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1RI8
 | | Crystal Structure of the Camelid Single Domain Antibody 1D2L19 in complex with Hen Egg White Lysozyme | | Descriptor: | GLYCEROL, Lysozyme C, camelid ANTIBODY HEAVY CHAIN | | Authors: | De Genst, E, Silence, K, Ghahroudi, M.A, Decanniere, K, Loris, R, Kinne, J, Wyns, L, Muyldermans, S. | | Deposit date: | 2003-11-17 | | Release date: | 2005-02-01 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Strong in vivo maturation compensates for structurally restricted H3 loops in antibody repertoires.
J.Biol.Chem., 280, 2005
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1RGA
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1RPG
 | | STRUCTURES OF RNASE A COMPLEXED WITH 3'-CMP AND D(CPA): ACTIVE SITE CONFORMATION AND CONSERVED WATER MOLECULES | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2'-DEOXYCYTIDINE-2'-DEOXYADENOSINE-3',5'-MONOPHOSPHATE, RIBONUCLEASE A | | Authors: | Zegers, I, Wyns, L, Palmer, R. | | Deposit date: | 1994-08-29 | | Release date: | 1994-12-20 | | Last modified: | 2024-06-05 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | The structures of RNase A complexed with 3'-CMP and d(CpA): active site conformation and conserved water molecules.
Protein Sci., 3, 1994
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1RPF
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1RXI
 | | pI258 arsenate reductase (ArsC) triple mutant C10S/C15A/C82S | | Descriptor: | Arsenate reductase, CHLORIDE ION, PERCHLORATE ION, ... | | Authors: | Messens, J, Van Molle, I, Vanhaesebrouck, P, Limbourg, M, Van Belle, K, Wahni, K, Martins, J.C, Loris, R, Wyns, L. | | Deposit date: | 2003-12-18 | | Release date: | 2004-06-01 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | The structure of a triple mutant of pI258 arsenate reductase from Staphylococcus aureus and its 5-thio-2-nitrobenzoic acid adduct.
Acta Crystallogr.,Sect.D, 60, 2004
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1DQ0
 | | Locked, metal-free concanavalin A, a minor species in solution | | Descriptor: | Concanavalin-Br | | Authors: | Bouckaert, J, Dewallef, Y, Poortmans, F, Wyns, L, Loris, R. | | Deposit date: | 1999-12-29 | | Release date: | 2000-01-19 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | The structural features of concanavalin A governing non-proline peptide isomerization
J.Biol.Chem., 275, 2000
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