7EV3
| |
7EV2
| |
5BOO
| Crystal structure of Plasmodium falciparum dihydroorotate dehydrogenase bound with Inhibitor DSM265 | Descriptor: | 2-(1,1-difluoroethyl)-5-methyl-N-[4-(pentafluoro-lambda~6~-sulfanyl)phenyl][1,2,4]triazolo[1,5-a]pyrimidin-7-amine, Dihydroorotate dehydrogenase (quinone), mitochondrial, ... | Authors: | Phillips, M, Deng, X, Tomchick, D. | Deposit date: | 2015-05-27 | Release date: | 2015-07-29 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria. Sci Transl Med, 7, 2015
|
|
7FDG
| SARS-COV-2 Spike RBDMACSp6 binding to hACE2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike protein S1 | Authors: | Wang, X, Cao, L. | Deposit date: | 2021-07-16 | Release date: | 2021-08-25 | Last modified: | 2024-10-09 | Method: | ELECTRON MICROSCOPY (3.69 Å) | Cite: | Characterization and structural basis of a lethal mouse-adapted SARS-CoV-2. Nat Commun, 12, 2021
|
|
7FDK
| SARS-COV-2 Spike RBDMACSp36 binding to mACE2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike protein S1 | Authors: | Wang, X, Cao, L. | Deposit date: | 2021-07-16 | Release date: | 2021-08-25 | Last modified: | 2022-03-23 | Method: | ELECTRON MICROSCOPY (3.69 Å) | Cite: | Characterization and structural basis of a lethal mouse-adapted SARS-CoV-2. Nat Commun, 12, 2021
|
|
7FDH
| SARS-COV-2 Spike RBDMACSp25 binding to hACE2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike protein S1 | Authors: | Wang, X, Cao, L. | Deposit date: | 2021-07-16 | Release date: | 2021-08-25 | Last modified: | 2022-03-23 | Method: | ELECTRON MICROSCOPY (3.72 Å) | Cite: | Characterization and structural basis of a lethal mouse-adapted SARS-CoV-2. Nat Commun, 12, 2021
|
|
7FDI
| SARS-COV-2 Spike RBDMACSp36 binding to hACE2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike protein S1 | Authors: | Wang, X, Cao, L. | Deposit date: | 2021-07-16 | Release date: | 2021-08-25 | Last modified: | 2022-03-23 | Method: | ELECTRON MICROSCOPY (3.12 Å) | Cite: | Characterization and structural basis of a lethal mouse-adapted SARS-CoV-2. Nat Commun, 12, 2021
|
|
7VY0
| Coxsackievirus B3 full particle at pH7.4 (VP3-234N) | Descriptor: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ... | Authors: | Wang, Q.L, Liu, C.C. | Deposit date: | 2021-11-13 | Release date: | 2022-01-19 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Molecular basis of differential receptor usage for naturally occurring CD55-binding and -nonbinding coxsackievirus B3 strains. Proc.Natl.Acad.Sci.USA, 119, 2022
|
|
7VXZ
| |
7VXH
| Coxsackievirus B3 full particle at pH7.4 (VP3-234Q) | Descriptor: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ... | Authors: | Wang, Q.L, Liu, C.C. | Deposit date: | 2021-11-12 | Release date: | 2022-01-19 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (2.95 Å) | Cite: | Molecular basis of differential receptor usage for naturally occurring CD55-binding and -nonbinding coxsackievirus B3 strains. Proc.Natl.Acad.Sci.USA, 119, 2022
|
|
6UX2
| Crystal structure of ZIKV RdRp in complex with STAT2 | Descriptor: | Nonstructural Protein 5, SULFATE ION, Signal transducer and activator of transcription 2, ... | Authors: | Wang, B, Song, J. | Deposit date: | 2019-11-06 | Release date: | 2020-07-08 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.01 Å) | Cite: | Structural basis for STAT2 suppression by flavivirus NS5. Nat.Struct.Mol.Biol., 27, 2020
|
|
6V0V
| Cryo-EM structure of mouse WT RAG1/2 NFC complex (DNA0) | Descriptor: | CALCIUM ION, DNA (30-MER), V(D)J recombination-activating protein 1, ... | Authors: | Chen, X, Yang, W, Gellert, M. | Deposit date: | 2019-11-19 | Release date: | 2020-01-29 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.61 Å) | Cite: | Cutting antiparallel DNA strands in a single active site. Nat.Struct.Mol.Biol., 27, 2020
|
|
4ZS6
| Receptor binding domain and Fab complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, S protein, fab Heavy Chain, ... | Authors: | Yu, X, Wang, X. | Deposit date: | 2015-05-13 | Release date: | 2015-09-02 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.166 Å) | Cite: | Structural basis for the neutralization of MERS-CoV by a human monoclonal antibody MERS-27 Sci Rep, 5, 2015
|
|
4RX0
| Crystal structure of Plasmodium falciparum dihydroorotate dehydrogenase bound with Inhibitor DSM265 | Descriptor: | 2-(1,1-difluoroethyl)-5-methyl-N-[4-(pentafluoro-lambda~6~-sulfanyl)phenyl][1,2,4]triazolo[1,5-a]pyrimidin-7-amine, Dihydroorotate dehydrogenase (quinone), mitochondrial, ... | Authors: | Deng, X, Phillips, M, Tomchick, D. | Deposit date: | 2014-12-08 | Release date: | 2015-07-29 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria. Sci Transl Med, 7, 2015
|
|
8D8N
| gRAMP non-match PFS target RNA | Descriptor: | RAMP superfamily protein, RNA (35-MER), RNA (5'-R(P*UP*CP*CP*GP*GP*GP*GP*CP*AP*GP*AP*AP*AP*AP*UP*UP*GP*GP*AP*CP*A)-3'), ... | Authors: | Hu, C, Nam, K.H, Schuler, G, Ke, A. | Deposit date: | 2022-06-08 | Release date: | 2022-08-31 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Craspase is a CRISPR RNA-guided, RNA-activated protease. Science, 377, 2022
|
|
8D9H
| gRAMP-TPR-CHAT match PFS target RNA(Craspase) | Descriptor: | CHAT domain protein, PHOSPHATE ION, RAMP superfamily protein, ... | Authors: | Hu, C, Nam, K.H, Schuler, G, Ke, A. | Deposit date: | 2022-06-09 | Release date: | 2023-06-14 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Craspase is a CRISPR RNA-guided, RNA-activated protease. Science, 377, 2022
|
|
8D9E
| gRAMP-match PFS target | Descriptor: | RAMP superfamily protein, RNA (36-MER), RNA (5'-R(P*UP*CP*CP*GP*GP*GP*GP*CP*AP*GP*AP*AP*AP*AP*UP*UP*GP*GP*GP*UP*A)-3'), ... | Authors: | Hu, C, Nam, K.H, Schuler, G, Ke, A. | Deposit date: | 2022-06-09 | Release date: | 2023-06-14 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.76 Å) | Cite: | Craspase is a CRISPR RNA-guided, RNA-activated protease. Science, 377, 2022
|
|
8D97
| Apo gRAMP | Descriptor: | RAMP superfamily protein, RNA (42-MER), ZINC ION | Authors: | Hu, C, Nam, K.H, Schuler, G, Ke, A. | Deposit date: | 2022-06-09 | Release date: | 2023-06-14 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Craspase is a CRISPR RNA-guided, RNA-activated protease. Science, 377, 2022
|
|
8D9F
| gRAMP-TPR-CHAT (Craspase) | Descriptor: | CHAT domain protein, RAMP superfamily protein, RNA (33-MER), ... | Authors: | Hu, C, Nam, K.H, Schuler, G, Ke, A. | Deposit date: | 2022-06-09 | Release date: | 2023-06-14 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (2.71 Å) | Cite: | Craspase is a CRISPR RNA-guided, RNA-activated protease. Science, 377, 2022
|
|
8D9G
| gRAMP-TPR-CHAT Non match PFS target RNA(Craspase) | Descriptor: | CHAT domain protein, RAMP superfamily protein, RNA (36-MER), ... | Authors: | Hu, C, Nam, K.H, Schuler, G, Ke, A. | Deposit date: | 2022-06-09 | Release date: | 2023-06-14 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (2.57 Å) | Cite: | Craspase is a CRISPR RNA-guided, RNA-activated protease. Science, 377, 2022
|
|
8D9I
| gRAMP non-matching PFS-with Mg | Descriptor: | RAMP superfamily protein, RNA (35-MER), RNA (5'-R(P*UP*CP*CP*GP*GP*GP*GP*CP*AP*GP*AP*AP*AP*AP*UP*UP*GP*GP*A)-3'), ... | Authors: | Hu, C, Nam, K.H, Schuler, G, Ke, A. | Deposit date: | 2022-06-09 | Release date: | 2023-06-14 | Method: | ELECTRON MICROSCOPY (3.62 Å) | Cite: | Craspase is a CRISPR RNA-guided, RNA-activated protease. Science, 377, 2022
|
|
8EBU
| XPC release from Core7-XPA-DNA (Cy5) | Descriptor: | DNA repair protein complementing XP-A cells, DNA repair protein complementing XP-C cells, DNA1, ... | Authors: | Kim, J, Yang, W. | Deposit date: | 2022-08-31 | Release date: | 2023-04-19 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Lesion recognition by XPC, TFIIH and XPA in DNA excision repair. Nature, 617, 2023
|
|
8EBV
| |
8EBS
| |
8EBT
| |