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5F22
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BU of 5f22 by Molmil
C-terminal domain of SARS-CoV nsp8 complex with nsp7
Descriptor: Non-structural protein, Non-structural protein 7
Authors:Li, S.
Deposit date:2015-12-01
Release date:2016-01-27
Last modified:2016-02-03
Method:X-RAY DIFFRACTION (2.155 Å)
Cite:C-terminal domain of SARS-CoV nsp8 complex with nsp7
To Be Published
6IS5
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BU of 6is5 by Molmil
P domain of GII.3-TV24 with A-tetrasaccharide complex
Descriptor: VP1 Capsid protein, alpha-L-fucopyranose-(1-2)-[2-acetamido-2-deoxy-alpha-D-galactopyranose-(1-3)]beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose
Authors:Yang, Y.
Deposit date:2018-11-15
Release date:2019-11-20
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.501 Å)
Cite:Structural basis of host ligand specificity change of GII porcine noroviruses from their closely related GII human noroviruses.
Emerg Microbes Infect, 8, 2019
6BA5
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BU of 6ba5 by Molmil
Potent and Selective Antitumor Activity of a T-Cell Engaging Bispecific Antibody Targeting a Membrane-Proximal Epitope of ROR1
Descriptor: Inactive tyrosine-protein kinase transmembrane receptor ROR1, Variable domain Heavy chain, antibody R11, ...
Authors:Park, H, Rader, C.
Deposit date:2017-10-12
Release date:2018-06-13
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Potent and selective antitumor activity of a T cell-engaging bispecific antibody targeting a membrane-proximal epitope of ROR1.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5TSR
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BU of 5tsr by Molmil
Crystal structure of PRL-3 phosphatase in complex with the Bateman domain of CNNM3 magnesium transporter
Descriptor: Metal transporter CNNM3, Protein tyrosine phosphatase type IVA 3
Authors:Kozlov, G, Zhang, H, Gehring, K.
Deposit date:2016-10-31
Release date:2017-02-08
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.188 Å)
Cite:PRL3 phosphatase active site is required for binding the putative magnesium transporter CNNM3.
Sci Rep, 7, 2017
8IN8
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BU of 8in8 by Molmil
Cryo-EM structure of the target ssDNA-bound SIR2-APAZ/Ago-gRNA quaternary complex
Descriptor: DNA (5'-D(P*AP*AP*CP*GP*AP*CP*GP*TP*CP*TP*AP*AP*GP*AP*AP*AP*CP*CP*AP*TP*TP*AP*A)-3'), MAGNESIUM ION, Piwi domain protein, ...
Authors:Zhang, H, Li, Z, Yu, G.M, Li, X.Z, Wang, X.S.
Deposit date:2023-03-08
Release date:2023-07-05
Last modified:2023-09-13
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural insights into mechanisms of Argonaute protein-associated NADase activation in bacterial immunity.
Cell Res., 33, 2023
8I88
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BU of 8i88 by Molmil
Cryo-EM structure of TIR-APAZ/Ago-gRNA complex
Descriptor: Piwi domain-containing protein, RNA (5'-R(P*GP*A)-3'), TIR domain-containing protein
Authors:Zhang, H, Li, Z, Yu, G.M, Li, X.Z, Wang, X.S.
Deposit date:2023-02-03
Release date:2023-07-05
Last modified:2023-09-13
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural insights into mechanisms of Argonaute protein-associated NADase activation in bacterial immunity.
Cell Res., 33, 2023
6J0Q
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BU of 6j0q by Molmil
Crystal structure of P domain from GII.11 swine norovirus
Descriptor: VP1 capsid protein
Authors:Chen, Y.
Deposit date:2018-12-25
Release date:2019-11-20
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis of host ligand specificity change of GII porcine noroviruses from their closely related GII human noroviruses.
Emerg Microbes Infect, 8, 2019
8XOH
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BU of 8xoh by Molmil
Cryo-EM structure of GPR30-Gq complex structure in the presence of E2
Descriptor: G-protein coupled estrogen receptor 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Liu, H, Xu, P, Xu, H.E.
Deposit date:2024-01-01
Release date:2024-04-10
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural and functional evidence that GPR30 is not a direct estrogen receptor.
Cell Res., 34, 2024
5UN5
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BU of 5un5 by Molmil
Frizzled-8 complex with designed surrogate Wnt agonist, crystal form 1
Descriptor: Designed Wnt agonist B12, Frizzled-8
Authors:Janda, C.Y, Garcia, K.C.
Deposit date:2017-01-30
Release date:2017-05-03
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.994 Å)
Cite:Surrogate Wnt agonists that phenocopy canonical Wnt and beta-catenin signalling.
Nature, 545, 2017
8XOJ
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BU of 8xoj by Molmil
Cryo-EM structure of GPR30-Gq complex structure in the presence of G-1
Descriptor: G-protein coupled estrogen receptor 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Liu, H, Xu, P, Xu, H.E.
Deposit date:2024-01-01
Release date:2024-04-10
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural and functional evidence that GPR30 is not a direct estrogen receptor.
Cell Res., 34, 2024
8XOI
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BU of 8xoi by Molmil
Cryo-EM structure of GPR30-Gq complex structure in the presence of fulvestrant
Descriptor: G-protein coupled estrogen receptor 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Liu, H, Xu, P, Xu, H.E.
Deposit date:2024-01-01
Release date:2024-04-10
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural and functional evidence that GPR30 is not a direct estrogen receptor.
Cell Res., 34, 2024
8XOG
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BU of 8xog by Molmil
Cryo-EM structure of apo-GPR30-Gq complex structure
Descriptor: G-protein coupled estrogen receptor 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Liu, H, Xu, P, Xu, H.E.
Deposit date:2024-01-01
Release date:2024-04-10
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural and functional evidence that GPR30 is not a direct estrogen receptor.
Cell Res., 34, 2024
8XOF
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BU of 8xof by Molmil
Cryo-EM structure of Lys05 bound GPR30-Gq complex structure
Descriptor: G protein subunit q, G-protein coupled estrogen receptor 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Liu, H, Xu, P, Xu, H.E.
Deposit date:2024-01-01
Release date:2024-04-10
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Structural and functional evidence that GPR30 is not a direct estrogen receptor.
Cell Res., 34, 2024
5V45
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BU of 5v45 by Molmil
Crystal structure of the F270M, K291M, L318M mutant of SR1 domain of human sacsin
Descriptor: Sacsin
Authors:Menade, M, Kozlov, G, Gehring, K.
Deposit date:2017-03-08
Release date:2017-05-24
Last modified:2018-08-29
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Structures of ubiquitin-like (Ubl) and Hsp90-like domains of sacsin provide insight into pathological mutations.
J. Biol. Chem., 293, 2018
5V46
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BU of 5v46 by Molmil
Crystal structure of the I113M, F270M, K291M, L308M mutant of SR1 domain of human sacsin
Descriptor: Sacsin
Authors:Menade, M, Kozlov, G, Gehring, K.
Deposit date:2017-03-08
Release date:2017-05-24
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structures of ubiquitin-like (Ubl) and Hsp90-like domains of sacsin provide insight into pathological mutations.
J. Biol. Chem., 293, 2018
5V47
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BU of 5v47 by Molmil
Crystal structure of the SR1 domain of lizard sacsin
Descriptor: Lizard sacsin, SULFATE ION
Authors:Pan, T, Menade, M, Kozlov, G, Gehring, K.
Deposit date:2017-03-08
Release date:2017-05-24
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Structures of ubiquitin-like (Ubl) and Hsp90-like domains of sacsin provide insight into pathological mutations.
J. Biol. Chem., 293, 2018
5V7Q
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BU of 5v7q by Molmil
Cryo-EM structure of the large ribosomal subunit from Mycobacterium tuberculosis bound with a potent linezolid analog
Descriptor: 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
Authors:Yang, K, Chang, J.-Y, Cui, Z, Zhang, J.
Deposit date:2017-03-20
Release date:2017-09-20
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural insights into species-specific features of the ribosome from the human pathogen Mycobacterium tuberculosis.
Nucleic Acids Res., 45, 2017
5UN6
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BU of 5un6 by Molmil
Frizzled-8 complex with designed surrogate Wnt agonist, A1 dataset
Descriptor: Designed Wnt agonist B12, Frizzled-8
Authors:Janda, C.Y, Garcia, K.C, Jude, K.M.
Deposit date:2017-01-30
Release date:2017-05-03
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Surrogate Wnt agonists that phenocopy canonical Wnt and beta-catenin signalling.
Nature, 545, 2017
5V44
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BU of 5v44 by Molmil
Crystal structure of the SR1 domain of human sacsin
Descriptor: GLYCEROL, Sacsin
Authors:Menade, M, Kozlov, G, Gehring, K.
Deposit date:2017-03-08
Release date:2017-05-24
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Structures of ubiquitin-like (Ubl) and Hsp90-like domains of sacsin provide insight into pathological mutations.
J. Biol. Chem., 293, 2018
3HW3
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BU of 3hw3 by Molmil
The crystal structure of avian influenza virus PA_N in complex with UMP
Descriptor: MAGNESIUM ION, Polymerase acidic protein, URIDINE-5'-MONOPHOSPHATE
Authors:Zhao, C, Lou, Z, Guo, Y, Ma, M, Chen, Y, Rao, Z.
Deposit date:2009-06-17
Release date:2009-10-13
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Nucleoside monophosphate complex structures of the endonuclease domain from the influenza virus polymerase PA subunit reveal the substrate binding site inside the catalytic center
J.Virol., 83, 2009
3HW4
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BU of 3hw4 by Molmil
Crystal structure of avian influenza A virus in complex with TMP
Descriptor: MAGNESIUM ION, Polymerase acidic protein, THYMIDINE-5'-PHOSPHATE
Authors:Zhao, C, Lou, Z, Guo, Y, Ma, M, Chen, Y, Rao, Z.
Deposit date:2009-06-17
Release date:2009-11-10
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Nucleoside monophosphate complex structures of the endonuclease domain from the influenza virus polymerase PA subunit reveal the substrate binding site inside the catalytic center
J.Virol., 83, 2009
4DT1
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BU of 4dt1 by Molmil
Crystal structure of the Psy3-Csm2 complex
Descriptor: Chromosome segregation in meiosis protein 2, ETHANOL, Platinum sensitivity protein 3
Authors:Tao, Y, Niu, L, Teng, M.
Deposit date:2012-02-20
Release date:2012-04-11
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.899 Å)
Cite:Structural analysis of Shu proteins reveals a DNA binding role essential for resisting damage
J.Biol.Chem., 287, 2012
4B4L
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BU of 4b4l by Molmil
CRYSTAL STRUCTURE OF AN ARD DAP-KINASE 1 MUTANT
Descriptor: DEATH-ASSOCIATED PROTEIN KINASE 1, PENTAETHYLENE GLYCOL, SULFATE ION
Authors:Temmerman, K, Pogenberg, V, Jonko, W, Wilmanns, M.
Deposit date:2012-07-31
Release date:2013-08-21
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:A Pef/Y Substrate Recognition and Signature Motif Plays a Critical Role in Dapk-Related Kinase Activity.
Chem.Biol., 21, 2014
3HW5
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BU of 3hw5 by Molmil
crystal structure of avian influenza virus PA_N in complex with AMP
Descriptor: ADENOSINE MONOPHOSPHATE, MAGNESIUM ION, Polymerase acidic protein
Authors:Zhao, C, Lou, Z, Guo, Y, Ma, M, Chen, Y, Liang, S, Rao, Z.
Deposit date:2009-06-17
Release date:2009-10-13
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Nucleoside monophosphate complex structures of the endonuclease domain from the influenza virus polymerase PA subunit reveal the substrate binding site inside the catalytic center
J.Virol., 83, 2009
3HW6
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BU of 3hw6 by Molmil
Crystal structure of avian influenza virus PA_N in complex with Mn
Descriptor: MANGANESE (II) ION, Polymerase acidic protein
Authors:Zhao, C, Lou, Z, Guo, Y, Ma, M, Chen, Y, Rao, Z.
Deposit date:2009-06-17
Release date:2009-10-13
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Nucleoside monophosphate complex structures of the endonuclease domain from the influenza virus polymerase PA subunit reveal the substrate binding site inside the catalytic center
J.Virol., 83, 2009

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数据于2024-07-10公开中

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