8IJQ
 
 | | The cryo-EM structure of human sphingomyelin synthase-related protein in complex with ceramide | | Descriptor: | N-((E,2S,3R)-1,3-DIHYDROXYOCTADEC-4-EN-2-YL)PALMITAMIDE, Sphingomyelin synthase-related protein 1 | | Authors: | Hu, K, Zhang, Q, Chen, Y, Yao, D, Zhou, L, Cao, Y. | | Deposit date: | 2023-02-27 | | Release date: | 2024-02-28 | | Last modified: | 2024-11-13 | | Method: | ELECTRON MICROSCOPY (3.45 Å) | | Cite: | Cryo-EM structure of human sphingomyelin synthase and its mechanistic implications for sphingomyelin synthesis.
Nat.Struct.Mol.Biol., 31, 2024
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7RMG
 | | Substance P bound to active human neurokinin 1 receptor in complex with miniGs/q70 | | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | | Authors: | Harris, J.A, Faust, B, Gondin, A.B, Daemgen, M.A, Suomivuori, C.M, Veldhuis, N.A, Cheng, Y, Dror, R.O, Thal, D, Manglik, A. | | Deposit date: | 2021-07-27 | | Release date: | 2021-11-03 | | Last modified: | 2024-11-06 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Selective G protein signaling driven by substance P-neurokinin receptor dynamics.
Nat.Chem.Biol., 18, 2022
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7RMI
 | | SP6-11 biased agonist bound to active human neurokinin 1 receptor in complex with miniGs/q70 | | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | | Authors: | Harris, J.A, Faust, B, Gondin, A.B, Daemgen, M.A, Suomivuori, C.M, Veldhuis, N.A, Cheng, Y, Dror, R.O, Thal, D, Manglik, A. | | Deposit date: | 2021-07-27 | | Release date: | 2021-11-03 | | Last modified: | 2024-11-13 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Selective G protein signaling driven by substance P-neurokinin receptor dynamics.
Nat.Chem.Biol., 18, 2022
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7RMH
 | | Substance P bound to active human neurokinin 1 receptor in complex with miniGs399 | | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | | Authors: | Harris, J.A, Faust, B, Gondin, A.B, Daemgen, M.A, Suomivuori, C.M, Veldhuis, N.A, Cheng, Y, Dror, R.O, Thal, D, Manglik, A. | | Deposit date: | 2021-07-27 | | Release date: | 2021-11-03 | | Last modified: | 2024-11-20 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Selective G protein signaling driven by substance P-neurokinin receptor dynamics.
Nat.Chem.Biol., 18, 2022
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8JWY
 | | Crystal structure of A2AR-T4L in complex with 2-118 | | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 3-[2-azanyl-6-[2-oxidanylidene-1-[[6-(2-oxidanylpropan-2-yl)pyridin-2-yl]methyl]pyridin-4-yl]pyrimidin-4-yl]-2-methyl-benzenecarbonitrile, Adenosine receptor A2a,Endolysin, ... | | Authors: | Weng, Y, Chen, Y, Xu, Y, Song, G. | | Deposit date: | 2023-06-29 | | Release date: | 2023-08-16 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.33 Å) | | Cite: | Structural insight into the dual-antagonistic mechanism of AB928 on adenosine A 2 receptors.
Sci China Life Sci, 67, 2024
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8JWZ
 | | Crystal structure of A2AR-T4L in complex with AB928 | | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 3-[2-azanyl-6-[1-[[6-(2-oxidanylpropan-2-yl)pyridin-2-yl]methyl]-1,2,3-triazol-4-yl]pyrimidin-4-yl]-2-methyl-benzenecarbonitrile, Adenosine receptor A2a,Endolysin, ... | | Authors: | Weng, Y, Chen, Y, Xu, Y, Song, G. | | Deposit date: | 2023-06-29 | | Release date: | 2023-08-16 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.37 Å) | | Cite: | Structural insight into the dual-antagonistic mechanism of AB928 on adenosine A 2 receptors.
Sci China Life Sci, 67, 2024
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3QJR
 | | The structure of and photolytic induced changes of carbon monoxide binding to the cytochrome ba3-oxidase from Thermus thermophilus | | Descriptor: | CARBON MONOXIDE, COPPER (I) ION, Cytochrome c oxidase polypeptide 2A, ... | | Authors: | Liu, B, Zhang, Y, Sage, J.T, Doukov, T, Chen, Y, Stout, C.D, Fee, J.A. | | Deposit date: | 2011-01-30 | | Release date: | 2012-01-25 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Structural changes that occur upon photolysis of the Fe(II)(a3)-CO complex in the cytochrome ba(3)-oxidase of Thermus thermophilus: A combined X-ray crystallographic and infrared spectral study demonstrates CO binding to Cu(B).
Biochim.Biophys.Acta, 1817, 2012
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8YSL
 | | Crystal structure of the Deinococcus wulumuqiensis CD-NTase DwCdnB in complex with UTP and ATP | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Nucleotidyltransferase, ... | | Authors: | Wang, Y.-C, Yang, C.-S, Hou, M.-H, Chen, Y. | | Deposit date: | 2024-03-23 | | Release date: | 2025-01-29 | | Method: | X-RAY DIFFRACTION (1.98 Å) | | Cite: | Structural insights into signaling promiscuity of the CBASS anti-phage defense system from a radiation-resistant bacterium.
Int.J.Biol.Macromol., 295, 2025
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8YSS
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8YSE
 | | Crystal structure of the Deinococcus wulumuqiensis CD-NTase DwCdnB in complex with dATP | | Descriptor: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, MAGNESIUM ION, Nucleotidyltransferase | | Authors: | Wang, Y.-C, Yang, C.-S, Hou, M.-H, Chen, Y. | | Deposit date: | 2024-03-22 | | Release date: | 2025-01-29 | | Method: | X-RAY DIFFRACTION (2.19 Å) | | Cite: | Structural insights into signaling promiscuity of the CBASS anti-phage defense system from a radiation-resistant bacterium.
Int.J.Biol.Macromol., 295, 2025
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8YSN
 | | Crystal structure of the Deinococcus wulumuqiensis CD-NTase DwCdnB Ear-cut mutant | | Descriptor: | Nucleotidyltransferase, PHOSPHATE ION | | Authors: | Wang, Y.-C, Yang, C.-S, Hou, M.-H, Chen, Y. | | Deposit date: | 2024-03-23 | | Release date: | 2025-01-29 | | Method: | X-RAY DIFFRACTION (2.01 Å) | | Cite: | Structural insights into signaling promiscuity of the CBASS anti-phage defense system from a radiation-resistant bacterium.
Int.J.Biol.Macromol., 295, 2025
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8YSQ
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8YSK
 | | Crystal structure of the Deinococcus wulumuqiensis CD-NTase DwCdnB in complex with UTP Mn | | Descriptor: | MANGANESE (II) ION, Nucleotidyltransferase, URIDINE 5'-TRIPHOSPHATE | | Authors: | Wang, Y.-C, Yang, C.-S, Hou, M.-H, Chen, Y. | | Deposit date: | 2024-03-23 | | Release date: | 2025-01-29 | | Method: | X-RAY DIFFRACTION (1.984 Å) | | Cite: | Structural insights into signaling promiscuity of the CBASS anti-phage defense system from a radiation-resistant bacterium.
Int.J.Biol.Macromol., 295, 2025
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8YSR
 | | Crystal structure of the Deinococcus wulumuqiensis CD-NTase DwCdnB in complex with hexatungstotellurate(VI) TEW | | Descriptor: | 6-tungstotellurate(VI), Nucleotidyltransferase | | Authors: | Wang, Y.-C, Yang, C.-S, Hou, M.-H, Chen, Y. | | Deposit date: | 2024-03-23 | | Release date: | 2025-01-29 | | Method: | X-RAY DIFFRACTION (2.04 Å) | | Cite: | Structural insights into signaling promiscuity of the CBASS anti-phage defense system from a radiation-resistant bacterium.
Int.J.Biol.Macromol., 295, 2025
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8YSC
 | | Crystal structure of the Deinococcus wulumuqiensis CD-NTase DwCdnB in complex with ATP (form 1) | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Nucleotidyltransferase | | Authors: | Wang, Y.-C, Yang, C.-S, Hou, M.-H, Chen, Y. | | Deposit date: | 2024-03-22 | | Release date: | 2025-01-29 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Structural insights into signaling promiscuity of the CBASS anti-phage defense system from a radiation-resistant bacterium.
Int.J.Biol.Macromol., 295, 2025
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8YSI
 | | Crystal structure of the Deinococcus wulumuqiensis CD-NTase DwCdnB in complex with UTP | | Descriptor: | Nucleotidyltransferase, URIDINE 5'-TRIPHOSPHATE | | Authors: | Wang, Y.-C, Yang, C.-S, Hou, M.-H, Chen, Y. | | Deposit date: | 2024-03-23 | | Release date: | 2025-01-29 | | Method: | X-RAY DIFFRACTION (1.897 Å) | | Cite: | Structural insights into signaling promiscuity of the CBASS anti-phage defense system from a radiation-resistant bacterium.
Int.J.Biol.Macromol., 295, 2025
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8YSM
 | | Crystal structure of the Deinococcus wulumuqiensis CD-NTase DwCdnB in complex with CTP Mn | | Descriptor: | CYTIDINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, Nucleotidyltransferase, ... | | Authors: | Wang, Y.-C, Yang, C.-S, Hou, M.-H, Chen, Y. | | Deposit date: | 2024-03-23 | | Release date: | 2025-01-29 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Structural insights into signaling promiscuity of the CBASS anti-phage defense system from a radiation-resistant bacterium.
Int.J.Biol.Macromol., 295, 2025
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8YSU
 | | Crystal structure of the Deinococcus wulumuqiensis CD-NTase DwCdnB in complex with CTP | | Descriptor: | CYTIDINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Nucleotidyltransferase | | Authors: | Wang, Y.-C, Yang, C.-S, Hou, M.-H, Chen, Y. | | Deposit date: | 2024-03-23 | | Release date: | 2025-01-29 | | Method: | X-RAY DIFFRACTION (1.944 Å) | | Cite: | Structural insights into signaling promiscuity of the CBASS anti-phage defense system from a radiation-resistant bacterium.
Int.J.Biol.Macromol., 295, 2025
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8YSD
 | | Crystal structure of the Deinococcus wulumuqiensis CD-NTase DwCdnB in complex with ATP (form 2) | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Nucleotidyltransferase | | Authors: | Wang, Y.-C, Yang, C.-S, Hou, M.-H, Chen, Y. | | Deposit date: | 2024-03-22 | | Release date: | 2025-01-29 | | Method: | X-RAY DIFFRACTION (1.61 Å) | | Cite: | Structural insights into signaling promiscuity of the CBASS anti-phage defense system from a radiation-resistant bacterium.
Int.J.Biol.Macromol., 295, 2025
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8YSO
 | | Crystal structure of the Deinococcus wulumuqiensis CD-NTase DwCdnB Ear-cut mutant in complex with ATP | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Nucleotidyltransferase, ... | | Authors: | Wang, Y.-C, Yang, C.-S, Hou, M.-H, Chen, Y. | | Deposit date: | 2024-03-23 | | Release date: | 2025-01-29 | | Method: | X-RAY DIFFRACTION (1.68 Å) | | Cite: | Structural insights into signaling promiscuity of the CBASS anti-phage defense system from a radiation-resistant bacterium.
Int.J.Biol.Macromol., 295, 2025
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8YSG
 | | Crystal structure of the Deinococcus wulumuqiensis CD-NTase DwCdnB in complex with GTP | | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Nucleotidyltransferase | | Authors: | Wang, Y.-C, Yang, C.-S, Hou, M.-H, Chen, Y. | | Deposit date: | 2024-03-22 | | Release date: | 2025-01-29 | | Method: | X-RAY DIFFRACTION (2.171 Å) | | Cite: | Structural insights into signaling promiscuity of the CBASS anti-phage defense system from a radiation-resistant bacterium.
Int.J.Biol.Macromol., 295, 2025
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8YSJ
 | | Crystal structure of the Deinococcus wulumuqiensis CD-NTase DwCdnB in complex with UMPNPP | | Descriptor: | 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine, Nucleotidyltransferase | | Authors: | Wang, Y.-C, Yang, C.-S, Hou, M.-H, Chen, Y. | | Deposit date: | 2024-03-23 | | Release date: | 2025-01-29 | | Method: | X-RAY DIFFRACTION (1.903 Å) | | Cite: | Structural insights into signaling promiscuity of the CBASS anti-phage defense system from a radiation-resistant bacterium.
Int.J.Biol.Macromol., 295, 2025
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3QJV
 | | The structure of and photolytic induced changes of carbon monoxide binding to the cytochrome ba3-oxidase from Thermus thermophilus | | Descriptor: | CARBON MONOXIDE, COPPER (I) ION, Cytochrome c oxidase polypeptide 2A, ... | | Authors: | Liu, B, Zhang, Y, Sage, J.T, Doukov, T, Chen, Y, Stout, C.D, Fee, J.A. | | Deposit date: | 2011-01-30 | | Release date: | 2012-01-25 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structural changes that occur upon photolysis of the Fe(II)(a3)-CO complex in the cytochrome ba(3)-oxidase of Thermus thermophilus: A combined X-ray crystallographic and infrared spectral study demonstrates CO binding to Cu(B).
Biochim.Biophys.Acta, 1817, 2012
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3QJS
 | | The structure of and photolytic induced changes of carbon monoxide binding to the cytochrome ba3-oxidase from Thermus thermophilus | | Descriptor: | CARBON MONOXIDE, COPPER (I) ION, Cytochrome c oxidase polypeptide 2A, ... | | Authors: | Liu, B, Zhang, Y, Sage, J.T, Doukov, T, Chen, Y, Stout, C.D, Fee, J.A. | | Deposit date: | 2011-01-30 | | Release date: | 2012-01-25 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structural changes that occur upon photolysis of the Fe(II)(a3)-CO complex in the cytochrome ba(3)-oxidase of Thermus thermophilus: A combined X-ray crystallographic and infrared spectral study demonstrates CO binding to Cu(B).
Biochim.Biophys.Acta, 1817, 2012
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3QJQ
 | | The structure of and photolytic induced changes of carbon monoxide binding to the cytochrome ba3-oxidase from Thermus thermophilus | | Descriptor: | CARBON MONOXIDE, COPPER (I) ION, Cytochrome c oxidase polypeptide 2A, ... | | Authors: | Liu, B, Zhang, Y, Sage, J.T, Doukov, T, Chen, Y, Stout, C.D, Fee, J.A. | | Deposit date: | 2011-01-30 | | Release date: | 2012-01-25 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Structural changes that occur upon photolysis of the Fe(II)(a3)-CO complex in the cytochrome ba(3)-oxidase of Thermus thermophilus: A combined X-ray crystallographic and infrared spectral study demonstrates CO binding to Cu(B).
Biochim.Biophys.Acta, 1817, 2012
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