Loading
PDBj
MenuPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDBDonate
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
2ZXD
DownloadVisualize
BU of 2zxd by Molmil
alpha-L-fucosidase complexed with inhibitor, iso-6FNJ
Descriptor: (2S,3R,4S,5R)-2-(1-methylethyl)piperidine-3,4,5-triol, Alpha-L-fucosidase, putative
Authors:Wu, H.-J, Ko, T.-P, Ho, C.-W, Lin, C.-H, Wang, A.H.-J.
Deposit date:2008-12-22
Release date:2009-12-08
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural basis of alpha-fucosidase inhibition by iminocyclitols with K(i) values in the micro- to picomolar range.
Angew.Chem.Int.Ed.Engl., 49, 2010
2ZX7
DownloadVisualize
BU of 2zx7 by Molmil
alpha-L-fucosidase complexed with inhibitor, F10-2C
Descriptor: Alpha-L-fucosidase, putative, N-{[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methylpiperidin-2-yl]methyl}-1H-indole-2-carboxamide
Authors:Wu, H.-J, Ko, T.-P, Ho, C.-W, Lin, C.-H, Wang, A.H.-J.
Deposit date:2008-12-19
Release date:2009-12-08
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Structural basis of alpha-fucosidase inhibition by iminocyclitols with K(i) values in the micro- to picomolar range.
Angew.Chem.Int.Ed.Engl., 49, 2010
2ZX8
DownloadVisualize
BU of 2zx8 by Molmil
alpha-L-fucosidase complexed with inhibitor, F10-2C-O
Descriptor: Alpha-L-fucosidase, putative, N-{[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methylpiperidin-2-yl]methyl}-1-benzofuran-2-carboxamide
Authors:Wu, H.-J, Ko, T.-P, Ho, C.-W, Lin, C.-H, Wang, A.H.-J.
Deposit date:2008-12-19
Release date:2009-12-08
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:Structural basis of alpha-fucosidase inhibition by iminocyclitols with K(i) values in the micro- to picomolar range.
Angew.Chem.Int.Ed.Engl., 49, 2010
2ZX6
DownloadVisualize
BU of 2zx6 by Molmil
alpha-L-fucosidase complexed with inhibitor, F10-1C
Descriptor: 2-(1H-indol-3-yl)-N-{[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methylpiperidin-2-yl]methyl}acetamide, Alpha-L-fucosidase, putative
Authors:Wu, H.-J, Ko, T.-P, Ho, C.-W, Lin, C.-H, Wang, A.H.-J.
Deposit date:2008-12-19
Release date:2009-12-08
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Structural basis of alpha-fucosidase inhibition by iminocyclitols with K(i) values in the micro- to picomolar range.
Angew.Chem.Int.Ed.Engl., 49, 2010
2ZX9
DownloadVisualize
BU of 2zx9 by Molmil
alpha-L-fucosidase complexed with inhibitor, B4
Descriptor: (2S)-2-cyclopentyl-2-phenyl-N-{[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methylpiperidin-2-yl]methyl}ethanamide, Alpha-L-fucosidase, putative
Authors:Wu, H.-J, Ko, T.-P, Ho, C.-W, Lin, C.-H, Wang, A.H.-J.
Deposit date:2008-12-22
Release date:2009-12-08
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:Structural basis of alpha-fucosidase inhibition by iminocyclitols with K(i) values in the micro- to picomolar range.
Angew.Chem.Int.Ed.Engl., 49, 2010
2ZE3
DownloadVisualize
BU of 2ze3 by Molmil
Crystal Structure of DFA0005 Complexed with alpha-Ketoglutarate: A Novel Member of the ICL/PEPM Superfamily from Alkali-tolerant Deinococcus ficus
Descriptor: 2-OXOGLUTARIC ACID, DFA0005
Authors:Liao, C.J, Chin, K.H, Chou, S.H.
Deposit date:2007-12-05
Release date:2008-08-12
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal structure of DFA0005 complexed with alpha-ketoglutarate: a novel member of the ICL/PEPM superfamily from alkali-tolerant Deinococcus ficus
Proteins, 73, 2008
7C8T
DownloadVisualize
BU of 7c8t by Molmil
Complex Structure of SARS-CoV-2 3CL Protease with TG-0205221
Descriptor: 3C-like proteinase, N-[(BENZYLOXY)CARBONYL]-O-(TERT-BUTYL)-L-THREONYL-3-CYCLOHEXYL-N-[(1S)-2-HYDROXY-1-{[(3S)-2-OXOPYRROLIDIN-3-YL]METHYL}ETHYL]-L-ALANINAMIDE
Authors:Lee, C.C, Wang, A.H.J, Kuo, C.J, Liang, P.H.
Deposit date:2020-06-03
Release date:2020-06-17
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Complex Structures and Cellular Activities of the Potent SARS-CoV-2 3CLpro Inhibitors Guiding Drug Discovery Against COVID-19
To Be Published
7C8R
DownloadVisualize
BU of 7c8r by Molmil
Complex Structure of SARS-CoV-2 3CL Protease with TG-0203770
Descriptor: 3C-like proteinase, ethyl (4R)-4-[[(2S)-4-methyl-2-[[(2S,3R)-3-[(2-methylpropan-2-yl)oxy]-2-(phenylmethoxycarbonylamino)butanoyl]amino]pentanoyl]amino]-5-[(3S)-2-oxidanylidenepyrrolidin-3-yl]pentanoate
Authors:Lee, C.C, Wang, A.H.J, Kuo, C.J, Liang, P.H.
Deposit date:2020-06-03
Release date:2020-06-17
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Complex Structures and Cellular Activities of the Potent SARS-CoV-2 3CLpro Inhibitors Guiding Drug Discovery Against COVID-19
To Be Published
2F4B
DownloadVisualize
BU of 2f4b by Molmil
Crystal structure of the ligand binding domain of human PPAR-gamma in complex with an agonist
Descriptor: (5-{3-[(6-BENZOYL-1-PROPYL-2-NAPHTHYL)OXY]PROPOXY}-1H-INDOL-1-YL)ACETIC ACID, Peroxisome proliferator-activated receptor gamma
Authors:Lu, I.L, Peng, Y.H, Mahindroo, N, Hsieh, H.P, Wu, S.Y.
Deposit date:2005-11-23
Release date:2006-02-14
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Indol-1-yl Acetic Acids as Peroxisome Proliferator-Activated Receptor Agonists: Design, Synthesis, Structural Biology, and Molecular Docking Studies
J.Med.Chem., 49, 2006
7QQR
DownloadVisualize
BU of 7qqr by Molmil
SpCas9 bound to AAVS1 off-target5 DNA substrate
Descriptor: 1,2-ETHANEDIOL, AAVS1 off-target5 non-target strand, AAVS1 off-target5 target strand, ...
Authors:Pacesa, M, Jinek, M.
Deposit date:2022-01-10
Release date:2022-10-26
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structural basis for Cas9 off-target activity.
Cell, 185, 2022
7QQV
DownloadVisualize
BU of 7qqv by Molmil
SpCas9 bound to FANCF off-target3 DNA substrate
Descriptor: CRISPR-associated endonuclease Cas9/Csn1, FANCF off-target3 non-target strand, FANCF off-target3 target strand, ...
Authors:Pacesa, M, Jinek, M.
Deposit date:2022-01-10
Release date:2022-10-26
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural basis for Cas9 off-target activity.
Cell, 185, 2022
7QR5
DownloadVisualize
BU of 7qr5 by Molmil
SpCas9 bound to FANCF off-target6 DNA substrate
Descriptor: 1,2-ETHANEDIOL, CRISPR-associated endonuclease Cas9/Csn1, FANCF off-target6 non-target strand, ...
Authors:Pacesa, M, Jinek, M.
Deposit date:2022-01-17
Release date:2022-10-26
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural basis for Cas9 off-target activity.
Cell, 185, 2022
7QQO
DownloadVisualize
BU of 7qqo by Molmil
SpCas9 bound to AAVS1 off-target1 DNA substrate
Descriptor: AAVS1 off-target1 non-target strand, AAVS1 off-target1 target strand, AAVS1 sgRNA, ...
Authors:Pacesa, M, Jinek, M.
Deposit date:2022-01-10
Release date:2022-10-26
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis for Cas9 off-target activity.
Cell, 185, 2022
7QQQ
DownloadVisualize
BU of 7qqq by Molmil
SpCas9 bound to AAVS1 off-target4 DNA substrate
Descriptor: 1,2-ETHANEDIOL, AAVS1 off-target4 non-target strand, AAVS1 off-target4 target strand, ...
Authors:Pacesa, M, Jinek, M.
Deposit date:2022-01-10
Release date:2022-10-26
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structural basis for Cas9 off-target activity.
Cell, 185, 2022
7QQU
DownloadVisualize
BU of 7qqu by Molmil
SpCas9 bound to FANCF off-target2 DNA substrate
Descriptor: CRISPR-associated endonuclease Cas9/Csn1, FANCF off-target2 non-target strand, FANCF off-target2 target strand, ...
Authors:Pacesa, M, Jinek, M.
Deposit date:2022-01-10
Release date:2022-10-26
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structural basis for Cas9 off-target activity.
Cell, 185, 2022
7QQT
DownloadVisualize
BU of 7qqt by Molmil
SpCas9 bound to FANCF off-target1 DNA substrate
Descriptor: CRISPR-associated endonuclease Cas9/Csn1, FANCF off-target1 non-target strand, FANCF off-target1 target strand, ...
Authors:Pacesa, M, Jinek, M.
Deposit date:2022-01-10
Release date:2022-10-26
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for Cas9 off-target activity.
Cell, 185, 2022
7QR8
DownloadVisualize
BU of 7qr8 by Molmil
SpCas9 bound to PTPRC off-target1 DNA substrate
Descriptor: CRISPR-associated endonuclease Cas9/Csn1, MAGNESIUM ION, POTASSIUM ION, ...
Authors:Pacesa, M, Jinek, M.
Deposit date:2022-01-10
Release date:2022-10-26
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structural basis for Cas9 off-target activity.
Cell, 185, 2022
7QQP
DownloadVisualize
BU of 7qqp by Molmil
SpCas9 bound to AAVS1 off-target3 DNA substrate
Descriptor: 1,2-ETHANEDIOL, AAVS1 off-target3 non-target strand, AAVS1 off-target3 target strand, ...
Authors:Pacesa, M, JInek, M.
Deposit date:2022-01-10
Release date:2022-10-26
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for Cas9 off-target activity.
Cell, 185, 2022
7QQS
DownloadVisualize
BU of 7qqs by Molmil
SpCas9 bound to FANCF on-target DNA substrate
Descriptor: CRISPR-associated endonuclease Cas9/Csn1, FANCF on-target non-target strand, FANCF on-target target strand, ...
Authors:Pacesa, M, Jinek, M.
Deposit date:2022-01-10
Release date:2022-10-26
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for Cas9 off-target activity.
Cell, 185, 2022
7QQX
DownloadVisualize
BU of 7qqx by Molmil
SpCas9 bound to FANCF off-target5 DNA substrate
Descriptor: CRISPR-associated endonuclease Cas9/Csn1, FANCF off-target5 non-target strand, FANCF off-target5 target strand, ...
Authors:Pacesa, M, Jinek, M.
Deposit date:2022-01-10
Release date:2022-10-26
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for Cas9 off-target activity.
Cell, 185, 2022
7QR0
DownloadVisualize
BU of 7qr0 by Molmil
SpCas9 bound to TRAC off-target1 DNA substrate
Descriptor: CRISPR-associated endonuclease Cas9/Csn1, MAGNESIUM ION, POTASSIUM ION, ...
Authors:Pacesa, M, Jinek, M.
Deposit date:2022-01-10
Release date:2022-10-26
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for Cas9 off-target activity.
Cell, 185, 2022
7QQZ
DownloadVisualize
BU of 7qqz by Molmil
SpCas9 bound to FANCF off-target7 DNA substrate
Descriptor: CRISPR-associated endonuclease Cas9/Csn1, FANCF off-target7 non-target strand, FANCF off-target7 target strand, ...
Authors:Pacesa, M, Jinek, M.
Deposit date:2022-01-10
Release date:2022-10-26
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural basis for Cas9 off-target activity.
Cell, 185, 2022
7QQW
DownloadVisualize
BU of 7qqw by Molmil
SpCas9 bound to FANCF off-target4 DNA substrate
Descriptor: CRISPR-associated endonuclease Cas9/Csn1, FANCF off-target4 non-target strand, FANCF off-target4 target strand, ...
Authors:Pacesa, M, Jinek, M.
Deposit date:2022-01-10
Release date:2022-10-26
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural basis for Cas9 off-target activity.
Cell, 185, 2022
7QR1
DownloadVisualize
BU of 7qr1 by Molmil
SpCas9 bound to TRAC off-target2 DNA substrate
Descriptor: CRISPR-associated endonuclease Cas9/Csn1, MAGNESIUM ION, POTASSIUM ION, ...
Authors:Pacesa, M, Jinek, M.
Deposit date:2022-01-10
Release date:2022-10-26
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for Cas9 off-target activity.
Cell, 185, 2022
7QR7
DownloadVisualize
BU of 7qr7 by Molmil
SpCas9 bound to AAVS1 off-target2 DNA substrate
Descriptor: AAVS1 off-target2 non-target strand, AAVS1 off-target2 target strand, AAVS1 sgRNA, ...
Authors:Pacesa, M, JInek, M.
Deposit date:2022-01-10
Release date:2022-10-26
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis for Cas9 off-target activity.
Cell, 185, 2022

238582

数据于2025-07-09公开中

PDB statisticsPDBj update infoContact PDBjnumon