8I9U
 
 | | Human TRiC-PhLP2A complex in the open state | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Phosducin-like protein 3, T-complex protein 1 subunit alpha, ... | | Authors: | Roh, S.H, Park, J, Kim, H, Lim, S. | | Deposit date: | 2023-02-07 | | Release date: | 2024-01-17 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | A structural vista of phosducin-like PhLP2A-chaperonin TRiC cooperation during the ATP-driven folding cycle.
Nat Commun, 15, 2024
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8I1U
 | | Human TRiC-PhLP2A complex in the closed state | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, MAGNESIUM ION, ... | | Authors: | Roh, S.H, Park, J, Kim, H, Lim, S. | | Deposit date: | 2023-01-13 | | Release date: | 2024-01-31 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (3.24 Å) | | Cite: | A structural vista of phosducin-like PhLP2A-chaperonin TRiC cooperation during the ATP-driven folding cycle.
Nat Commun, 15, 2024
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8I6J
 | | The focused refinement of CCT3-PhLP2A from TRiC-PhLP2A complex in the open state | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Phosducin-like protein 3, T-complex protein 1 subunit gamma | | Authors: | Roh, S.H, Park, J, Kim, H, Lim, S. | | Deposit date: | 2023-01-28 | | Release date: | 2024-01-31 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (3.82 Å) | | Cite: | A structural vista of phosducin-like PhLP2A-chaperonin TRiC cooperation during the ATP-driven folding cycle.
Nat Commun, 15, 2024
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5V7I
 | | Crystal structure of homo sapiens serine hydroxymethyltransferase 2 (mitochondrial) (SHMT2), in complex with glycine, PLP and folate-competitive pyrazolopyran inhibitor: 6-amino-4-isopropyl-3-methyl-4-(3-(pyrrolidin-1-yl)-5-(trifluoromethyl)phenyl)-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile | | Descriptor: | (4R)-6-amino-3-methyl-4-(propan-2-yl)-4-[3-(pyrrolidin-1-yl)-5-(trifluoromethyl)phenyl]-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | | Authors: | Ducker, G.S, Ghergurovich, J.M, Mainolfi, N, Suri, V, Jeong, S, Friedman, A, Manfredi, M, Kim, H, Rabinowitz, J.D. | | Deposit date: | 2017-03-20 | | Release date: | 2017-10-11 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.47 Å) | | Cite: | Human SHMT inhibitors reveal defective glycine import as a targetable metabolic vulnerability of diffuse large B-cell lymphoma.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5XD0
 | | Apo Structure of Beta-1,3-1,4-glucanase from Paenibacillus sp.X4 | | Descriptor: | DI(HYDROXYETHYL)ETHER, Glucanase, TRIETHYLENE GLYCOL | | Authors: | Baek, S.C, Ho, T.-H, Kang, L.-W, Kim, H. | | Deposit date: | 2017-03-24 | | Release date: | 2017-04-19 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.79 Å) | | Cite: | Improvement of enzyme activity of beta-1,3-1,4-glucanase from Paenibacillus sp. X4 by error-prone PCR and structural insights of mutated residues.
Appl. Microbiol. Biotechnol., 101, 2017
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3KYF
 | | Crystal structure of P4397 complexed with c-di-GMP | | Descriptor: | GUANOSINE-5'-MONOPHOSPHATE, Putative uncharacterized protein | | Authors: | Ryu, K.S, Ko, J, Kim, H, Choi, B.S. | | Deposit date: | 2009-12-06 | | Release date: | 2010-04-14 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structure of PP4397 Reveals the Molecular Basis for Different c-di-GMP Binding Modes by Pilz Domain Proteins.
J.Mol.Biol., 398, 2010
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3KYG
 | | Crystal structure of VCA0042 (L135R) complexed with c-di-GMP | | Descriptor: | GUANOSINE-5'-MONOPHOSPHATE, Putative uncharacterized protein VCA0042 | | Authors: | Ryu, K.S, Ko, J, Kim, H, Choi, B.S. | | Deposit date: | 2009-12-06 | | Release date: | 2010-04-14 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structure of PP4397 Reveals the Molecular Basis for Different c-di-GMP Binding Modes by Pilz Domain Proteins.
J.Mol.Biol., 398, 2010
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7FDA
 | | CryoEM Structure of Reconstituted V-ATPase, state1 | | Descriptor: | Fusion of yeast V-type proton ATPase subunit H(NT) and human V-type proton ATPase subunit H(CT), V-type proton ATPase subunit B, V-type proton ATPase subunit C, ... | | Authors: | Khan, M.M, Lee, S, Oot, R.A, Couoh-Cardel, S, KIm, H, Wilkens, S, Roh, S.H. | | Deposit date: | 2021-07-16 | | Release date: | 2021-12-22 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (4.2 Å) | | Cite: | CryoEM Structures of Reconstituted V-ATPase and Oxr1-bound V1 Reveal a Novel Mechanism of Regulation.
Embo J., 2021
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7FDB
 | | CryoEM Structures of Reconstituted V-ATPase,State2 | | Descriptor: | Fusion of yeast V-type proton ATPase subunit H(NT) and human V-type proton ATPase subunit H(CT), V-type proton ATPase subunit B, V-type proton ATPase subunit C, ... | | Authors: | Khan, M.M, Lee, S, Oot, R.A, Couoh-Cardel, S, KIm, H, Wilkens, S, Roh, S.H. | | Deposit date: | 2021-07-16 | | Release date: | 2021-12-22 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (4.8 Å) | | Cite: | CryoEM Structures of Reconstituted V-ATPase and Oxr1-bound V1 Reveal a Novel Mechanism of Regulation.
Embo J., 2021
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7FDC
 | | CryoEM Structures of Reconstituted V-ATPase, state3 | | Descriptor: | Fusion of yeast V-type proton ATPase subunit H(NT) and human V-type proton ATPase subunit H(CT), V-type proton ATPase subunit B, V-type proton ATPase subunit C, ... | | Authors: | Khan, M.M, Lee, S, Oot, R.A, Couoh-Cardel, S, KIm, H, Wilkens, S, Roh, S.H. | | Deposit date: | 2021-07-16 | | Release date: | 2021-12-22 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (6.6 Å) | | Cite: | CryoEM Structures of Reconstituted V-ATPase and Oxr1-bound V1 Reveal a Novel Mechanism of Regulation.
Embo J., 2021
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7FDE
 | | CryoEM Structures of Reconstituted V-ATPase, Oxr1 bound V1 | | Descriptor: | Oxidation resistance protein 1, V-type proton ATPase subunit B, V-type proton ATPase subunit C, ... | | Authors: | Khan, M.M, Lee, S, Oot, R.A, Couoh-Cardel, S, KIm, H, Wilkens, S, Roh, S.H. | | Deposit date: | 2021-07-16 | | Release date: | 2021-12-29 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | CryoEM Structures of Reconstituted V-ATPase and Oxr1-bound V1 Reveal a Novel Mechanism of Regulation.
Embo J., 2021
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1Y0Q
 | | Crystal structure of an active group I ribozyme-product complex | | Descriptor: | 5'-R(*GP*CP*UP*U)-3', Group I ribozyme, MAGNESIUM ION, ... | | Authors: | Golden, B.L, Kim, H, Chase, E. | | Deposit date: | 2004-11-16 | | Release date: | 2004-12-21 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (3.6 Å) | | Cite: | Crystal structure of a phage Twort group I ribozyme-product complex
Nat.Struct.Mol.Biol., 12, 2005
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2ZFC
 | | X-ray crystal structure of an engineered N-terminal HIV-1 GP41 trimer with enhanced stability and potency | | Descriptor: | HIV-1 GP41 | | Authors: | Dwyer, J.J, Wilson, K.L, Martin, K, Seedorff, J.E, Hasan, A, Kim, H. | | Deposit date: | 2007-12-29 | | Release date: | 2008-04-22 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Design of an engineered N-terminal HIV-1 gp41 trimer with enhanced stability and potency
Protein Sci., 17, 2008
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3GN4
 | | Myosin lever arm | | Descriptor: | CALCIUM ION, Calmodulin, MAGNESIUM ION, ... | | Authors: | Mukherjea, M, Llinas, P, Kim, H, Travaglia, M, Safer, D, Zong, A.B, Menetrey, J, Franzini-Armstrong, C, Selvin, P.R, Houdusse, A, Sweeney, H.L. | | Deposit date: | 2009-03-16 | | Release date: | 2009-09-08 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Myosin VI dimerization triggers an unfolding of a three-helix bundle in order to extend its reach
Mol.Cell, 35, 2009
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2L1U
 | | Structure-Functional Analysis of Mammalian MsrB2 protein | | Descriptor: | Methionine-R-sulfoxide reductase B2, mitochondrial, ZINC ION | | Authors: | Aachmann, F.L, Del Conte, R, Kwak, G, Kim, H, Gladyshev, V.N, Dikiy, A. | | Deposit date: | 2010-08-06 | | Release date: | 2010-08-18 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Structure-Functional Analysis of Mammalian MsrB2 protein
To be Published
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7WBK
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7WBM
 | | Crystal structure of Legionella pneumophila effector protein Lpg0081 | | Descriptor: | Lpg0081, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE | | Authors: | Lee, J, Kim, H, Oh, B.H. | | Deposit date: | 2021-12-17 | | Release date: | 2022-06-15 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Reversible modification of mitochondrial ADP/ATP translocases by paired Legionella effector proteins.
Proc.Natl.Acad.Sci.USA, 119, 2022
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1S1M
 | | Crystal Structure of E. Coli CTP Synthetase | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, CTP synthase, IODIDE ION, ... | | Authors: | Endrizzi, J.A, Kim, H, Anderson, P.M, Baldwin, E.P. | | Deposit date: | 2004-01-06 | | Release date: | 2004-06-15 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal Structure of Escherichia coli Cytidine Triphosphate Synthetase, a Nucleotide-Regulated Glutamine Amidotransferase/ATP-Dependent Amidoligase Fusion Protein and Homologue of Anticancer and Antiparasitic Drug Targets
Biochemistry, 43, 2004
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1PVP
 | | BASIS FOR A SWITCH IN SUBSTRATE SPECIFICITY: CRYSTAL STRUCTURE OF SELECTED VARIANT OF CRE SITE-SPECIFIC RECOMBINASE, ALSHG BOUND TO THE ENGINEERED RECOGNITION SITE LOXM7 | | Descriptor: | 34-MER, Recombinase cre | | Authors: | Baldwin, E.P, Martin, S.S, Abel, J, Gelato, K.A, Kim, H, Schultz, P.G, Santoro, S.W. | | Deposit date: | 2003-06-28 | | Release date: | 2004-02-17 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | A specificity switch in selected cre recombinase variants is mediated by macromolecular plasticity and water.
Chem.Biol., 10, 2003
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1PVQ
 | | BASIS FOR A SWITCH IN SUBSTRATE SPECIFICITY: CRYSTAL STRUCTURE OF SELECTED VARIANT OF CRE SITE-SPECIFIC RECOMBINASE, LNSGG BOUND TO THE ENGINEERED RECOGNITION SITE LOXM7 | | Descriptor: | DNA 34-MER, Recombinase cre | | Authors: | Baldwin, E.P, Martin, S.S, Abel, J, Gelato, K.A, Kim, H, Schultz, P.G, Santoro, S.W. | | Deposit date: | 2003-06-28 | | Release date: | 2004-02-17 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | A specificity switch in selected cre recombinase variants is mediated by macromolecular plasticity and water.
Chem.Biol., 10, 2003
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1PVR
 | | BASIS FOR A SWITCH IN SUBSTRATE SPECIFICITY: CRYSTAL STRUCTURE OF SELECTED VARIANT OF CRE SITE-SPECIFIC RECOMBINASE, LNSGG BOUND TO THE LOXP (WILDTYPE) RECOGNITION SITE | | Descriptor: | 34-MER, Recombinase CRE | | Authors: | Baldwin, E.P, Martin, S.S, Abel, J, Gelato, K.A, Kim, H, Schultz, P.G, Santoro, S.W. | | Deposit date: | 2003-06-28 | | Release date: | 2004-02-17 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | A specificity switch in selected cre recombinase variants is mediated by macromolecular plasticity and water.
Chem.Biol., 10, 2003
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6KF3
 | | Cryo-EM structure of Thermococcus kodakarensis RNA polymerase | | Descriptor: | DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit A'', DNA-directed RNA polymerase subunit D, ... | | Authors: | Jun, S.-H, Hyun, J, Jeong, H, Cha, J.S, Kim, H, Bartlett, M.S, Cho, H.-S, Murakami, K.S. | | Deposit date: | 2019-07-06 | | Release date: | 2020-07-01 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Direct binding of TFE alpha opens DNA binding cleft of RNA polymerase.
Nat Commun, 11, 2020
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6AF2
 | | Crystal structure of N-terminus deletion mutant of Mycobacterium avium diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase | | Descriptor: | DI(HYDROXYETHYL)ETHER, HIT domain-containing protein, PENTAETHYLENE GLYCOL, ... | | Authors: | Mori, S, Honda, N, Kim, H, Rimbara, E, Shibayama, K. | | Deposit date: | 2018-08-08 | | Release date: | 2019-08-14 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (3.001 Å) | | Cite: | Crystal structure of N-terminus deletion mutant of Mycobacterium avium diadenosine tetraphosphate phosphorylase
To Be Published
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6KF9
 | | Cryo-EM structure of Thermococcus kodakarensis RNA polymerase | | Descriptor: | DNA (27-MER), DNA (5'-D(P*TP*CP*GP*GP*TP*AP*AP*TP*CP*AP*CP*GP*CP*TP*CP*C)-3'), DNA-directed RNA polymerase subunit, ... | | Authors: | Jun, S.-H, Hyun, J, Jeong, H, Cha, J.S, Kim, H, Bartlett, M.S, Cho, H.-S, Murakami, K.S. | | Deposit date: | 2019-07-07 | | Release date: | 2020-07-01 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (3.79 Å) | | Cite: | Direct binding of TFE alpha opens DNA binding cleft of RNA polymerase.
Nat Commun, 11, 2020
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6KF4
 | | Cryo-EM structure of Thermococcus kodakarensis RNA polymerase | | Descriptor: | DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit A'', DNA-directed RNA polymerase subunit D, ... | | Authors: | Jun, S.-H, Hyun, J, Jeong, H, Cha, J.S, Kim, H, Bartlett, M.S, Cho, H.-S, Murakami, K.S. | | Deposit date: | 2019-07-06 | | Release date: | 2020-07-01 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (3.97 Å) | | Cite: | Direct binding of TFE alpha opens DNA binding cleft of RNA polymerase.
Nat Commun, 11, 2020
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