6LUB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6lub by Molmil](/molmil-images/mine/6lub) | Crystal Structure of EGFR(L858R/T790M/C797S) in complex with CH7233163 | Descriptor: | Epidermal growth factor receptor, N-[2-(1-cyclopropylsulfonylpyrazol-4-yl)pyrimidin-4-yl]-7-(4-methylpiperazin-1-yl)-5-propan-2-yl-9-[2,2,2-tris(fluoranyl)ethoxy]pyrido[4,3-b]indol-3-amine | Authors: | Kawauchi, H, Fukami, T.A, Sato, S, Endo, M, Torizawa, T, Kashima, K, Chiba, T, Sakamoto, H. | Deposit date: | 2020-01-27 | Release date: | 2020-10-07 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.315 Å) | Cite: | CH7233163 Overcomes Osimertinib-Resistant EGFR-Del19/T790M/C797S Mutation. Mol.Cancer Ther., 19, 2020
|
|
6LUD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6lud by Molmil](/molmil-images/mine/6lud) | Crystal Structure of EGFR(L858R/T790M/C797S) in complex with Osimertinib | Descriptor: | Epidermal growth factor receptor, N-(2-{[2-(dimethylamino)ethyl](methyl)amino}-4-methoxy-5-{[4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl]amino}phenyl)prop-2-enamide | Authors: | Kawauchi, H, Fukami, T.A, Sato, S, Endo, M, Torizawa, T, Kashima, K, Chiba, T, Sakamoto, H. | Deposit date: | 2020-01-27 | Release date: | 2020-10-07 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | CH7233163 Overcomes Osimertinib-Resistant EGFR-Del19/T790M/C797S Mutation. Mol.Cancer Ther., 19, 2020
|
|
7PKJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7pkj by Molmil](/molmil-images/mine/7pkj) | Streptococcus pyogenes apo GapN | Descriptor: | BETA-MERCAPTOETHANOL, GLYCEROL, Putative NADP-dependent glyceraldehyde-3-phosphate dehydrogenase, ... | Authors: | Schindelin, H, Albert, L. | Deposit date: | 2021-08-25 | Release date: | 2022-03-16 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.989 Å) | Cite: | The Non-phosphorylating Glyceraldehyde-3-Phosphate Dehydrogenase GapN Is a Potential New Drug Target in Streptococcus pyogenes. Front Microbiol, 13, 2022
|
|
7PKC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7pkc by Molmil](/molmil-images/mine/7pkc) | Streptococcus pyogenes Apo-GapN C284S variant | Descriptor: | GLYCEROL, Putative NADP-dependent glyceraldehyde-3-phosphate dehydrogenase, SULFATE ION | Authors: | Schindelin, H, Albert, L. | Deposit date: | 2021-08-25 | Release date: | 2022-03-16 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | The Non-phosphorylating Glyceraldehyde-3-Phosphate Dehydrogenase GapN Is a Potential New Drug Target in Streptococcus pyogenes. Front Microbiol, 13, 2022
|
|
5X7X
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5x7x by Molmil](/molmil-images/mine/5x7x) | The crystal structure of the nucleosome containing H3.3 at 2.18 angstrom resolution | Descriptor: | CHLORIDE ION, DNA (146-MER), Histone H2A type 1-B/E, ... | Authors: | Arimura, Y, Taguchi, H, Kurumizaka, H. | Deposit date: | 2017-02-27 | Release date: | 2017-04-19 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.184 Å) | Cite: | Crystal Structure and Characterization of Novel Human Histone H3 Variants, H3.6, H3.7, and H3.8 Biochemistry, 56, 2017
|
|
5Z5E
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5z5e by Molmil](/molmil-images/mine/5z5e) | |
5XM0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5xm0 by Molmil](/molmil-images/mine/5xm0) | The mouse nucleosome structure containing H2A, H2B type3-A, H3.3, and H4 | Descriptor: | DNA (146-MER), Histone H2A type 1-B, Histone H2B type 3-A, ... | Authors: | Taguchi, H, Horikoshi, N, Kurumizaka, H. | Deposit date: | 2017-05-12 | Release date: | 2018-03-07 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.874 Å) | Cite: | Histone H3.3 sub-variant H3mm7 is required for normal skeletal muscle regeneration. Nat Commun, 9, 2018
|
|
1EKS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1eks by Molmil](/molmil-images/mine/1eks) | ASP128ALA VARIANT OF MOAC PROTEIN FROM E. COLI | Descriptor: | L(+)-TARTARIC ACID, MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN C | Authors: | Schindelin, H, Liu, M.T.W, Wuebbens, M.M, Rajagopalan, K.V. | Deposit date: | 2000-03-09 | Release date: | 2000-09-20 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Insights into molybdenum cofactor deficiency provided by the crystal structure of the molybdenum cofactor biosynthesis protein MoaC. Structure Fold.Des., 8, 2000
|
|
6REH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6reh by Molmil](/molmil-images/mine/6reh) | Crystal structure of Pizza6-S with Cu2+ | Descriptor: | COPPER (II) ION, GLYCEROL, Pizza6-S, ... | Authors: | Noguchi, H, Clarke, D.E, Gryspeerdt, J.L, Feyter, S.D, Voet, A.R.D. | Deposit date: | 2019-04-12 | Release date: | 2019-07-31 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | Artificial beta-propeller protein-based hydrolases. Chem.Commun.(Camb.), 55, 2019
|
|
6REJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6rej by Molmil](/molmil-images/mine/6rej) | Crystal structure of Pizza6-SH with Zn2+ | Descriptor: | Pizza6-SH, SULFATE ION, ZINC ION | Authors: | Noguchi, H, Clarke, D.E, Gryspeerdt, J.L, Feyter, S.D, Voet, A.R.D. | Deposit date: | 2019-04-12 | Release date: | 2019-07-31 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Artificial beta-propeller protein-based hydrolases. Chem.Commun.(Camb.), 55, 2019
|
|
6REN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ren by Molmil](/molmil-images/mine/6ren) | Crystal structure of 3fPizza6-SH with Zn2+ | Descriptor: | 3fPizza6-SH, GLYCEROL, ISOPROPYL ALCOHOL, ... | Authors: | Noguchi, H, Clarke, D.E, Gryspeerdt, J.L, Feyter, S.D, Voet, A.R.D. | Deposit date: | 2019-04-12 | Release date: | 2019-07-31 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Artificial beta-propeller protein-based hydrolases. Chem.Commun.(Camb.), 55, 2019
|
|
5XM1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5xm1 by Molmil](/molmil-images/mine/5xm1) | The mouse nucleosome structure containing H2A, H2B type3-A, H3mm7, and H4 | Descriptor: | DNA (146-MER), Histone H2A type 1-B, Histone H2B type 3-A, ... | Authors: | Taguchi, H, Horikoshi, N, Kurumizaka, H. | Deposit date: | 2017-05-12 | Release date: | 2018-03-07 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.45 Å) | Cite: | Histone H3.3 sub-variant H3mm7 is required for normal skeletal muscle regeneration. Nat Commun, 9, 2018
|
|
6REG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6reg by Molmil](/molmil-images/mine/6reg) | Crystal structure of Pizza6-S with Zn2+ | Descriptor: | GLYCEROL, Pizza6-S, ZINC ION | Authors: | Noguchi, H, Clarke, D.E, Gryspeerdt, J.L, Feyter, S.D, Voet, A.R.D. | Deposit date: | 2019-04-12 | Release date: | 2019-07-31 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Artificial beta-propeller protein-based hydrolases. Chem.Commun.(Camb.), 55, 2019
|
|
6REK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6rek by Molmil](/molmil-images/mine/6rek) | Crystal structure of Pizza6-SH with Cu2+ | Descriptor: | COPPER (II) ION, GLYCEROL, Pizza6-SH | Authors: | Noguchi, H, Clarke, D.E, Gryspeerdt, J.L, Feyter, S.D, Voet, A.R.D. | Deposit date: | 2019-04-12 | Release date: | 2019-07-31 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | Artificial beta-propeller protein-based hydrolases. Chem.Commun.(Camb.), 55, 2019
|
|
1EKR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1ekr by Molmil](/molmil-images/mine/1ekr) | MOAC PROTEIN FROM E. COLI | Descriptor: | MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN C | Authors: | Schindelin, H, Liu, M.T.W, Wuebbens, M.M, Rajagopalan, K.V. | Deposit date: | 2000-03-09 | Release date: | 2000-09-20 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Insights into molybdenum cofactor deficiency provided by the crystal structure of the molybdenum cofactor biosynthesis protein MoaC. Structure Fold.Des., 8, 2000
|
|
1X1D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1x1d by Molmil](/molmil-images/mine/1x1d) | Crystal structure of BchU complexed with S-adenosyl-L-homocysteine and Zn-bacteriopheophorbide d | Descriptor: | CrtF-related protein, GLYCEROL, S-ADENOSYL-L-HOMOCYSTEINE, ... | Authors: | Yamaguchi, H, Wada, K, Fukuyama, K. | Deposit date: | 2005-04-04 | Release date: | 2006-07-18 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal Structures of BchU, a Methyltransferase Involved in Bacteriochlorophyll c Biosynthesis, and its Complex with S-adenosylhomocysteine: Implications for Reaction Mechanism. J.Mol.Biol., 360, 2006
|
|
1X1B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1x1b by Molmil](/molmil-images/mine/1x1b) | Crystal structure of BchU complexed with S-adenosyl-L-homocysteine | Descriptor: | CrtF-related protein, GLYCEROL, S-ADENOSYL-L-HOMOCYSTEINE, ... | Authors: | Yamaguchi, H, Wada, K, Fukuyama, K. | Deposit date: | 2005-04-03 | Release date: | 2006-07-18 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal Structures of BchU, a Methyltransferase Involved in Bacteriochlorophyll c Biosynthesis, and its Complex with S-adenosylhomocysteine: Implications for Reaction Mechanism. J.Mol.Biol., 360, 2006
|
|
1X19
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1x19 by Molmil](/molmil-images/mine/1x19) | Crystal structure of BchU involved in bacteriochlorophyll c biosynthesis | Descriptor: | CrtF-related protein, SULFATE ION | Authors: | Yamaguchi, H, Wada, K, Fukuyama, K. | Deposit date: | 2005-04-02 | Release date: | 2006-07-18 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.27 Å) | Cite: | Crystal Structures of BchU, a Methyltransferase Involved in Bacteriochlorophyll c Biosynthesis, and its Complex with S-adenosylhomocysteine: Implications for Reaction Mechanism. J.Mol.Biol., 360, 2006
|
|
1X1C
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1x1c by Molmil](/molmil-images/mine/1x1c) | Crystal structure of BchU complexed with S-adenosyl-L-homocysteine and Zn2+ | Descriptor: | CrtF-related protein, GLYCEROL, S-ADENOSYL-L-HOMOCYSTEINE, ... | Authors: | Yamaguchi, H, Wada, K, Fukuyama, K. | Deposit date: | 2005-04-03 | Release date: | 2006-07-18 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Crystal Structures of BchU, a Methyltransferase Involved in Bacteriochlorophyll c Biosynthesis, and its Complex with S-adenosylhomocysteine: Implications for Reaction Mechanism. J.Mol.Biol., 360, 2006
|
|
1X1A
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1x1a by Molmil](/molmil-images/mine/1x1a) | Crystal structure of BchU complexed with S-adenosyl-L-methionine | Descriptor: | CrtF-related protein, GLYCEROL, S-ADENOSYLMETHIONINE, ... | Authors: | Yamaguchi, H, Wada, K, Fukuyama, K. | Deposit date: | 2005-04-03 | Release date: | 2006-07-18 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal Structures of BchU, a Methyltransferase Involved in Bacteriochlorophyll c Biosynthesis, and its Complex with S-adenosylhomocysteine: Implications for Reaction Mechanism. J.Mol.Biol., 360, 2006
|
|
3D24
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3d24 by Molmil](/molmil-images/mine/3d24) | Crystal structure of ligand-binding domain of estrogen-related receptor alpha (ERRalpha) in complex with the peroxisome proliferators-activated receptor coactivator-1alpha box3 peptide (PGC-1alpha) | Descriptor: | Peroxisome proliferator-activated receptor gamma coactivator 1-alpha, Steroid hormone receptor ERR1 | Authors: | Moras, D, Greschik, H, Flaig, R, Sato, Y, Rochel, N, Structural Proteomics in Europe (SPINE) | Deposit date: | 2008-05-07 | Release date: | 2008-06-10 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.11 Å) | Cite: | Communication between the ERR{alpha} Homodimer Interface and the PGC-1{alpha} Binding Surface via the Helix 8-9 Loop. J.Biol.Chem., 283, 2008
|
|
3WFL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3wfl by Molmil](/molmil-images/mine/3wfl) | Crtstal structure of glycoside hydrolase family 5 beta-mannanase from Talaromyces trachyspermus | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... | Authors: | Suzuki, K, Ichinose, H, Kamino, K, Ogasawara, W, Kaneko, S, Fushinobu, S. | Deposit date: | 2013-07-19 | Release date: | 2014-07-23 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Purification, cloning, functional expression, structure, and characterization of a thermostable beta-mannanase from Talaromyces trachyspermus and its efficiency in production of mannooligosaccharides from coffee wastes To be Published
|
|
5Y6Q
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5y6q by Molmil](/molmil-images/mine/5y6q) | |
1YSE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1yse by Molmil](/molmil-images/mine/1yse) | Solution structure of the MAR-binding domain of SATB1 | Descriptor: | DNA-binding protein SATB1 | Authors: | Yamasaki, K, Yamaguchi, H. | Deposit date: | 2005-02-08 | Release date: | 2006-01-03 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution Structure and DNA-binding Mode of the Matrix Attachment Region-binding Domain of the Transcription Factor SATB1 That Regulates the T-cell Maturation J.Biol.Chem., 281, 2006
|
|
7FG6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7fg6 by Molmil](/molmil-images/mine/7fg6) | |