3D24

Crystal structure of ligand-binding domain of estrogen-related receptor alpha (ERRalpha) in complex with the peroxisome proliferators-activated receptor coactivator-1alpha box3 peptide (PGC-1alpha)

Summary for 3D24

Entry DOI	10.2210/pdb3d24/pdb
Related	1XB7
Descriptor	Steroid hormone receptor ERR1, Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (3 entities in total)
Functional Keywords	nuclear receptor, ligand binding domain, coactivator, dna-binding, metal-binding, nucleus, phosphoprotein, transcription, transcription regulation, zinc, zinc-finger, polymorphism, rna-binding, structural genomics, structural proteomics in europe, spine
Biological source	Homo sapiens More
Cellular location	Nucleus: P11474 Q9UBK2
Total number of polymer chains	4
Total formula weight	60501.74
Authors	Moras, D.,Greschik, H.,Flaig, R.,Sato, Y.,Rochel, N.,Structural Proteomics in Europe (SPINE) (deposition date: 2008-05-07, release date: 2008-06-10, Last modification date: 2023-08-30)
Primary citation	Greschik, H.,Althage, M.,Flaig, R.,Sato, Y.,Chavant, V.,Peluso-Iltis, C.,Choulier, L.,Cronet, P.,Rochel, N.,Schule, R.,Stromstedt, P.E.,Moras, D. Communication between the ERR{alpha} Homodimer Interface and the PGC-1{alpha} Binding Surface via the Helix 8-9 Loop. J.Biol.Chem., 283:20220-20230, 2008 Cited by PubMed: 18441008 DOI: 10.1074/jbc.M801920200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.11 Å)

Structure validation