1UAW
 
 | | Solution structure of the N-terminal RNA-binding domain of mouse Musashi1 | | Descriptor: | mouse-musashi-1 | | Authors: | Miyanoiri, Y, Kobayashi, H, Watanabe, M, Ikeda, T, Nagata, T, Okano, H, Uesugi, S, Katahira, M. | | Deposit date: | 2003-03-24 | | Release date: | 2004-03-24 | | Last modified: | 2023-12-27 | | Method: | SOLUTION NMR | | Cite: | Origin of higher affinity to RNA of the N-terminal RNA-binding domain than that of the C-terminal one of a mouse neural protein, musashi1, as revealed by comparison of their structures, modes of interaction, surface electrostatic potentials, and backbone dynamics
J.Biol.Chem., 278, 2003
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6K84
 | | Structure of anti-prion RNA aptamer | | Descriptor: | RNA (25-MER) | | Authors: | Mashima, T, Lee, J.H, Hayashi, T, Nagata, T, Kinoshita, M, Katahira, M. | | Deposit date: | 2019-06-11 | | Release date: | 2020-04-01 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Development and structural determination of an anti-PrPCaptamer that blocks pathological conformational conversion of prion protein.
Sci Rep, 10, 2020
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1IQT
 | | Solution structure of the C-terminal RNA-binding domain of heterogeneous nuclear ribonucleoprotein D0 (AUF1) | | Descriptor: | heterogeneous nuclear ribonucleoprotein D0 | | Authors: | Katahira, M, Miyanoiri, Y, Enokizono, Y, Matsuda, G, Nagata, T, Ishikawa, F, Uesugi, S. | | Deposit date: | 2001-08-01 | | Release date: | 2002-08-07 | | Last modified: | 2023-12-27 | | Method: | SOLUTION NMR | | Cite: | Structure of the C-terminal RNA-binding domain of hnRNP D0 (AUF1), its interactions with RNA and DNA, and change in backbone dynamics upon complex formation with DNA.
J.Mol.Biol., 311, 2001
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2KBO
 | | Structure, interaction, and real-time monitoring of the enzymatic reaction of wild type APOBEC3G | | Descriptor: | DNA dC->dU-editing enzyme APOBEC-3G, ZINC ION | | Authors: | Furukawa, A, Nagata, T, Matsugami, A, Habu, Y, Sugiyama, R, Hayashi, F, Kobayashi, N, Yokoyama, S, Takaku, H, Katahira, M. | | Deposit date: | 2008-12-04 | | Release date: | 2009-02-03 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Structure, interaction and real-time monitoring of the enzymatic reaction of wild-type APOBEC3G
Embo J., 28, 2009
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5X3Z
 | | Solution structure of musashi1 RBD2 in complex with RNA | | Descriptor: | RNA (5'-R(*GP*UP*AP*GP*U)-3'), RNA-binding protein Musashi homolog 1 | | Authors: | Iwaoka, R, Nagata, T, Tsuda, K, Imai, T, Okano, H, Kobayashi, N, Katahira, M. | | Deposit date: | 2017-02-09 | | Release date: | 2017-12-13 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Structural Insight into the Recognition of r(UAG) by Musashi-1 RBD2, and Construction of a Model of Musashi-1 RBD1-2 Bound to the Minimum Target RNA
Molecules, 22, 2017
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5X3Y
 | | Refined solution structure of musashi1 RBD2 | | Descriptor: | RNA-binding protein Musashi homolog 1 | | Authors: | Iwaoka, R, Nagata, T, Tsuda, K, Imai, T, Okano, H, Kobayashi, N, Katahira, M. | | Deposit date: | 2017-02-09 | | Release date: | 2017-12-13 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Structural Insight into the Recognition of r(UAG) by Musashi-1 RBD2, and Construction of a Model of Musashi-1 RBD1-2 Bound to the Minimum Target RNA
Molecules, 22, 2017
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2RS2
 | | 1H, 13C, and 15N Chemical Shift Assignments for Musashi1 RBD1:r(GUAGU) complex | | Descriptor: | RNA (5'-R(*GP*UP*AP*GP*U)-3'), RNA-binding protein Musashi homolog 1 | | Authors: | Ohyama, T, Nagata, T, Tsuda, K, Imai, T, Okano, H, Yamazaki, T, Katahira, M. | | Deposit date: | 2011-06-27 | | Release date: | 2011-12-28 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Structure of Musashi1 in a complex with target RNA: the role of aromatic stacking interactions
Nucleic Acids Res., 2011
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2RU7
 | | Refined structure of RNA aptamer in complex with the partial binding peptide of prion protein | | Descriptor: | P16 peptide from Major prion protein, RNA_(5'-R(*GP*GP*AP*GP*GP*AP*GP*GP*AP*GP*GP*A)-3') | | Authors: | Hayashi, T, Oshima, H, Mashima, T, Nagata, T, Katahira, M, Kinoshita, M. | | Deposit date: | 2013-12-24 | | Release date: | 2014-05-21 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Binding of an RNA aptamer and a partial peptide of a prion protein: crucial importance of water entropy in molecular recognition.
Nucleic Acids Res., 42, 2014
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2RUG
 | | Refined solution structure of the first RNA recognition motif domain in CPEB3 | | Descriptor: | Cytoplasmic polyadenylation element-binding protein 3 | | Authors: | Tsuda, K, Kuwasako, K, Nagata, T, Takahashi, M, Kigawa, T, Kobayashi, N, Guntert, P, Shirouzu, M, Yokoyama, S, Muto, Y, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2014-04-15 | | Release date: | 2014-09-17 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Novel RNA recognition motif domain in the cytoplasmic polyadenylation element binding protein 3.
Proteins, 82, 2014
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2DNL
 | | Solution structure of RNA binding domain in Cytoplasmic polyadenylation element binding protein 3 | | Descriptor: | cytoplasmic polyadenylation element binding protein 3 | | Authors: | Tsuda, K, Nagata, T, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2006-04-26 | | Release date: | 2006-10-26 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of RNA binding domain in Cytoplasmic polyadenylation element binding protein 3
To be Published
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2DNY
 | | Solution structure of the third RNA binding domain of FBP-interacting repressor, SIAHBP1 | | Descriptor: | Fuse-binding protein-interacting repressor, isoform b | | Authors: | Suzuki, S, Nagata, T, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2006-04-27 | | Release date: | 2007-04-17 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the third RNA binding domain of FBP-interacting repressor, SIAHBP1
To be Published
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1WEL
 | | Solution structure of RNA binding domain in NP_006038 | | Descriptor: | RNA-binding protein 12 | | Authors: | Someya, T, Muto, Y, Nagata, T, Suzuki, S, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2004-05-25 | | Release date: | 2005-08-23 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of RNA binding domain in NP_006038
To be Published
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1WG1
 | | Solution structure of RNA binding domain in BAB13405(homolog EXC-7) | | Descriptor: | KIAA1579 protein | | Authors: | Tsuda, K, Muto, Y, Nagata, T, Suzuki, S, Someya, T, Kigawa, T, Terada, T, Shirouzu, M, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2004-05-27 | | Release date: | 2004-11-27 | | Last modified: | 2022-03-02 | | Method: | SOLUTION NMR | | Cite: | Solution structure of RNA binding domain in BAB13405(homolog EXC-7)
To be Published
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1WI8
 | | Solution structure of the RNA binding domain of eukaryotic initiation factor 4B | | Descriptor: | Eukaryotic translation initiation factor 4B | | Authors: | Suzuki, S, Muto, Y, Nagata, T, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2004-05-28 | | Release date: | 2004-11-28 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the RNA binding domain of eukaryotic initiation factor 4B
To be Published
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1WI6
 | | Solution structure of the RNA binding domain from mouse hypothetical protein BAB23670 | | Descriptor: | Hypothetical protein (RIKEN cDNA 1300006N24) | | Authors: | Suzuki, S, Muto, Y, Nagata, T, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2004-05-28 | | Release date: | 2005-06-07 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the RNA binding domain from mouse hypothetical protein BAB23670
To be Published
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2RPB
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3TK5
 | | Factor Xa in complex with D102-4380 | | Descriptor: | 4-{3-[(4-chlorophenyl)amino]-3-oxopropyl}-3-({[5-(propan-2-yl)-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridin-2-yl]carbonyl}amino)benzoic acid, CALCIUM ION, Factor X heavy chain, ... | | Authors: | Suzuki, M, Mochizuki, A, Nagata, T, Takano, H, Kanno, H, Kishida, M, Ohta, T. | | Deposit date: | 2011-08-25 | | Release date: | 2012-08-29 | | Last modified: | 2017-11-08 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Zwitter ionic potent durable orally active Factor Xa inhibitor.
To be Published
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3TK6
 | | factor Xa in complex with D46-5241 | | Descriptor: | CALCIUM ION, Factor X heavy chain, Factor X light chain, ... | | Authors: | Suzuki, M, Mochizuki, A, Nagata, T, Takano, H, Kanno, H, Kishida, M, Ohta, T. | | Deposit date: | 2011-08-25 | | Release date: | 2012-08-29 | | Last modified: | 2017-11-08 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Zwitter ionic potent durable orally active Factor Xa inhibitor.
To be Published
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2EI6
 | | FACTOR XA IN COMPLEX WITH THE INHIBITOR (-)-cis-N1-[(5-Chloroindol-2-yl)carbonyl]-N2-[(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)carbonyl]-1,2-cyclohexanediamine | | Descriptor: | CALCIUM ION, Coagulation factor X, heavy chain, ... | | Authors: | Suzuki, M. | | Deposit date: | 2007-03-12 | | Release date: | 2008-03-18 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Cycloalkanediamine derivatives as novel blood coagulation factor Xa inhibitors.
Bioorg.Med.Chem.Lett., 17, 2007
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2EI7
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2EI8
 | | FACTOR XA IN COMPLEX WITH THE INHIBITOR (1S,2R,4S)-N1-[(5-chloroindol-2-yl)carbonyl]-4-(N,N-dimethylcarbamoyl)-N2-[(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)carbonyl]-1,2-cyclohexanediamine | | Descriptor: | CALCIUM ION, Coagulation factor X, heavy chain, ... | | Authors: | Suzuki, M. | | Deposit date: | 2007-03-12 | | Release date: | 2008-03-18 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Discovery of N-{(1R,2S,5S)-2-{[(5-Chloroindol-2-yl)carbonyl]amino}-5-[(dimethylamino)carbonyl]cyclohexyl}-5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamide hydrochloride: A Novel, Potent and Orally Active Direct Inhibitor of Factor Xa
To be Published
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3Q3K
 | | Factor Xa in complex with a phenylenediamine derivative | | Descriptor: | Activated factor Xa heavy chain, CALCIUM ION, Factor X light chain, ... | | Authors: | Suzuki, M, Imai, E. | | Deposit date: | 2010-12-22 | | Release date: | 2011-12-28 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Design, synthesis and SAR of novel ethylenediamine and phenylenediamine derivatives as factor Xa inhibitors.
Bioorg.Med.Chem.Lett., 21, 2011
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7FBV
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7PL9
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1JQN
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