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2EI7

FACTOR XA IN COMPLEX WITH THE INHIBITOR trans-N1-[(5-Chloroindol-2-yl)carbonyl]-N2-[(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)carbonyl]-1,2-cyclohexanediamine

Summary for 2EI7
Entry DOI10.2210/pdb2ei7/pdb
Related1v3x 1wu1 2EI6 2EI8 2d1j
DescriptorCoagulation factor X, heavy chain, Coagulation factor X, light chain, CALCIUM ION, ... (5 entities in total)
Functional Keywordsglycoprotein, hydrolase, serine protease, plasma, blood coagulation factor, protein inhibitor complex, calcium-binding
Biological sourceHomo sapiens (human)
More
Cellular locationSecreted: P00742 P00742
Total number of polymer chains2
Total formula weight32745.69
Authors
Suzuki, M. (deposition date: 2007-03-12, release date: 2008-03-18, Last modification date: 2024-10-23)
Primary citationNagata, T.,Yoshino, T.,Haginoya, N.,Yoshikawa, K.,Isobe, Y.,Furugohri, T.,Kanno, H.
Cycloalkanediamine derivatives as novel blood coagulation factor Xa inhibitors
To be Published,
Experimental method
X-RAY DIFFRACTION (2.3 Å)
Structure validation

227344

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