1SMR
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7WBU
| Cryo-EM structure of bovine NLRP9 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, NACHT, LRR and PYD domains-containing protein 9 | Authors: | Kamitsukasa, Y, Shimizu, T, Ohto, U. | Deposit date: | 2021-12-17 | Release date: | 2022-04-06 | Last modified: | 2022-04-27 | Method: | ELECTRON MICROSCOPY (3.42 Å) | Cite: | The structure of NLRP9 reveals a unique C-terminal region with putative regulatory function. Febs Lett., 596, 2022
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7WBT
| Crystal structure of bovine NLRP9 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, NACHT, LRR and PYD domains-containing protein 9 | Authors: | Kamitsukasa, Y, Shimizu, T, Ohto, U. | Deposit date: | 2021-12-17 | Release date: | 2022-04-06 | Last modified: | 2022-04-27 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | The structure of NLRP9 reveals a unique C-terminal region with putative regulatory function. Febs Lett., 596, 2022
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6MUP
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6MUO
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7CFL
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1YNN
| Taq RNA polymerase-rifampicin complex | Descriptor: | DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ... | Authors: | Campbell, E.A, Pavlova, O, Zenkin, N, Leon, F, Irschik, H, Jansen, R, Severinov, K, Darst, S.A. | Deposit date: | 2005-01-24 | Release date: | 2005-03-15 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structural, functional, and genetic analysis of sorangicin inhibition of bacterial RNA polymerase Embo J., 24, 2005
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7XW8
| Crystal structure of Lysine Specific Demethylase 1 (LSD1) with TAK-418 distomer, FAD-adduct | Descriptor: | GLYCEROL, Lysine-specific histone demethylase 1A, MAGNESIUM ION, ... | Authors: | Oki, H. | Deposit date: | 2022-05-26 | Release date: | 2022-10-12 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Design, synthesis, and structure-activity relationship of TAK-418 and its derivatives as a novel series of LSD1 inhibitors with lowered risk of hematological side effects. Eur.J.Med.Chem., 239, 2022
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6UHC
| CryoEM structure of human Arp2/3 complex with bound NPFs | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin-related protein 2, Actin-related protein 2/3 complex subunit 1B, ... | Authors: | Zimmet, A, van Eeuwen, T, Dominguez, R. | Deposit date: | 2019-09-27 | Release date: | 2020-07-01 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Cryo-EM structure of NPF-bound human Arp2/3 complex and activation mechanism. Sci Adv, 6, 2020
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7VTQ
| Cryo-EM structure of mouse NLRP3 (full-length) dodecamer | Descriptor: | 1-[4-(2-oxidanylpropan-2-yl)furan-2-yl]sulfonyl-3-(1,2,3,5-tetrahydro-s-indacen-4-yl)urea, ADENOSINE-5'-DIPHOSPHATE, NACHT, ... | Authors: | Ohto, U, Shimizu, T. | Deposit date: | 2021-10-30 | Release date: | 2022-03-09 | Last modified: | 2022-03-23 | Method: | ELECTRON MICROSCOPY (3.55 Å) | Cite: | Structural basis for the oligomerization-mediated regulation of NLRP3 inflammasome activation. Proc.Natl.Acad.Sci.USA, 119, 2022
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7VTP
| Cryo-EM structure of PYD-deleted human NLRP3 hexamer | Descriptor: | 1-[4-(2-oxidanylpropan-2-yl)furan-2-yl]sulfonyl-3-(1,2,3,5-tetrahydro-s-indacen-4-yl)urea, ADENOSINE-5'-DIPHOSPHATE, NACHT, ... | Authors: | Ohto, U, Shimizu, T. | Deposit date: | 2021-10-30 | Release date: | 2022-03-09 | Last modified: | 2022-03-23 | Method: | ELECTRON MICROSCOPY (3.23 Å) | Cite: | Structural basis for the oligomerization-mediated regulation of NLRP3 inflammasome activation. Proc.Natl.Acad.Sci.USA, 119, 2022
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