7OWN
 
 | | HsNMT1 in complex with both MyrCoA and peptide AKSFSKPR | | Descriptor: | ALA-LYS-SER-PHE-SER-LYS-PRO-ARG, GLYCEROL, Glycylpeptide N-tetradecanoyltransferase 1, ... | | Authors: | Dian, C, Giglione, C, Meinnel, T. | | Deposit date: | 2021-06-18 | | Release date: | 2022-12-21 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural and Large-scale Analysis Unveil the Intertwined Paths Promoting NMT-catalyzed Lysine and Glycine Myristoylation.
J.Mol.Biol., 434, 2022
|
|
7OWM
 | | HsNMT1 in complex with both MyrCoA and HCPA substrate peptide GKQNSKLR | | Descriptor: | GLYCEROL, Glycylpeptide N-tetradecanoyltransferase 1, Neuron-specific calcium-binding protein hippocalcin, ... | | Authors: | Dian, C, Giglione, C, Meinnel, T. | | Deposit date: | 2021-06-18 | | Release date: | 2022-12-21 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Structural and Large-scale Analysis Unveil the Intertwined Paths Promoting NMT-catalyzed Lysine and Glycine Myristoylation.
J.Mol.Biol., 434, 2022
|
|
7R4K
 | | Crystal structure of human mitochondrial NAD kinase | | Descriptor: | MAGNESIUM ION, NAD kinase 2, mitochondrial, ... | | Authors: | Labesse, G, Mary, C, Gelin, M, Lionne, C. | | Deposit date: | 2022-02-08 | | Release date: | 2022-07-06 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (3.33 Å) | | Cite: | Crystal structure of human NADK2 reveals a dimeric organization and active site occlusion by lysine acetylation.
Mol.Cell, 82, 2022
|
|
7R4J
 | | Crystal structure of human mitochondrial NAD kinase | | Descriptor: | CALCIUM ION, NAD kinase 2, mitochondrial | | Authors: | Labesse, G, Mary, C, Gelin, M, Lionne, C. | | Deposit date: | 2022-02-08 | | Release date: | 2022-07-06 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (2.95 Å) | | Cite: | Crystal structure of human NADK2 reveals a dimeric organization and active site occlusion by lysine acetylation.
Mol.Cell, 82, 2022
|
|
7R4L
 | | Crystal structure of human mitochondrial NAD kinase | | Descriptor: | FE (III) ION, NAD kinase 2, mitochondrial, ... | | Authors: | Labesse, G, Mary, C, Gelin, M, Lionne, C. | | Deposit date: | 2022-02-08 | | Release date: | 2022-07-06 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Crystal structure of human NADK2 reveals a dimeric organization and active site occlusion by lysine acetylation.
Mol.Cell, 82, 2022
|
|
7R4M
 | | Crystal structure of mitochondrial NAD kinase | | Descriptor: | CALCIUM ION, NAD kinase 2, mitochondrial, ... | | Authors: | Labesse, G, Mary, C, Gelin, M, Lionne, C. | | Deposit date: | 2022-02-08 | | Release date: | 2022-07-06 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (2.29 Å) | | Cite: | Crystal structure of human NADK2 reveals a dimeric organization and active site occlusion by lysine acetylation.
Mol.Cell, 82, 2022
|
|
4JE7
 | | Crystal structure of a human-like mitochondrial peptide deformylase in complex with actinonin | | Descriptor: | ACTINONIN, Peptide deformylase 1A, chloroplastic/mitochondrial, ... | | Authors: | Fieulaine, S, Meinnel, T, Giglione, C. | | Deposit date: | 2013-02-26 | | Release date: | 2014-02-26 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Understanding the highly efficient catalysis of prokaryotic peptide deformylases by shedding light on the determinants specifying the low activity of the human counterpart.
Acta Crystallogr.,Sect.D, 70, 2014
|
|
6SK2
 | | HsNMT1 in complex with both MyrCoA and Acetylated-GKSFSKPR peptide reveals N-terminal Lysine Myristoylation | | Descriptor: | Apoptosis-inducing factor 3, COENZYME A, GLYCEROL, ... | | Authors: | Dian, C, Riviere, F.B, Asensio, T, Giglione, C, Meinnel, T. | | Deposit date: | 2019-08-14 | | Release date: | 2020-03-18 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.90000653 Å) | | Cite: | High-resolution snapshots of human N-myristoyltransferase in action illuminate a mechanism promoting N-terminal Lys and Gly myristoylation.
Nat Commun, 11, 2020
|
|
6SKJ
 | | DeltaC2 C-terminal truncation of HsNMT1 in complex with MyrCoA and GNCFSKPR substrates | | Descriptor: | Apoptosis-inducing factor 3, COENZYME A, GLYCEROL, ... | | Authors: | Dian, C, Riviere, F.B, Asensio, T, Giglione, C, Meinnel, T. | | Deposit date: | 2019-08-15 | | Release date: | 2020-03-18 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | High-resolution snapshots of human N-myristoyltransferase in action illuminate a mechanism promoting N-terminal Lys and Gly myristoylation.
Nat Commun, 11, 2020
|
|
6SK8
 | | DeltaC3 C-terminal truncation of HsNMT1 in complex with MyrCoA and GDCFSKPR substrates | | Descriptor: | Apoptosis-inducing factor 3, CHLORIDE ION, GLYCEROL, ... | | Authors: | Dian, C, Riviere, F.B, Asensio, T, Giglione, C, Meinnel, T. | | Deposit date: | 2019-08-14 | | Release date: | 2020-03-18 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.87 Å) | | Cite: | High-resolution snapshots of human N-myristoyltransferase in action illuminate a mechanism promoting N-terminal Lys and Gly myristoylation.
Nat Commun, 11, 2020
|
|
6SJZ
 | | HsNMT1 in complex with both MyrCoA and Acetylated-GNCFSKPR substrates | | Descriptor: | Apoptosis-inducing factor 3, CHLORIDE ION, GLYCEROL, ... | | Authors: | Dian, C, Riviere, F.B, Asensio, T, Giglione, C, Meinnel, T. | | Deposit date: | 2019-08-14 | | Release date: | 2020-03-18 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.995 Å) | | Cite: | High-resolution snapshots of human N-myristoyltransferase in action illuminate a mechanism promoting N-terminal Lys and Gly myristoylation.
Nat Commun, 11, 2020
|
|
6SK3
 | | C-terminal HsNMT1 deltaC3 truncation in complex with both MyrCoA and GNCFSKPR substrates | | Descriptor: | Apoptosis-inducing factor 3, GLYCEROL, Glycylpeptide N-tetradecanoyltransferase 1, ... | | Authors: | Dian, C, Riviere, F.B, Asensio, T, Giglione, C, Meinnel, T. | | Deposit date: | 2019-08-14 | | Release date: | 2020-03-18 | | Last modified: | 2024-05-15 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | High-resolution snapshots of human N-myristoyltransferase in action illuminate a mechanism promoting N-terminal Lys and Gly myristoylation.
Nat Commun, 11, 2020
|
|
3O3J
 | |
3M6P
 | |
3PN4
 | | Crystal structure of Arabidopsis thaliana petide deformylase 1B (AtPDF1B) in complex with actinonin (crystallized in PEG-550-MME) | | Descriptor: | ACTINONIN, Peptide deformylase 1B, chloroplastic, ... | | Authors: | Fieulaine, S, Meinnel, T, Giglione, C. | | Deposit date: | 2010-11-18 | | Release date: | 2011-06-08 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Trapping conformational States along ligand-binding dynamics of Peptide deformylase: the impact of induced fit on enzyme catalysis.
Plos Biol., 9, 2011
|
|
3PN2
 | |
3PN6
 | |
3PN5
 | |
3PN3
 | | Crystal structure of Arabidopsis thaliana petide deformylase 1B (AtPDF1B) in complex with inhibitor 21 | | Descriptor: | Peptide deformylase 1B, chloroplastic, ZINC ION, ... | | Authors: | Fieulaine, S, Meinnel, T, Giglione, C. | | Deposit date: | 2010-11-18 | | Release date: | 2011-06-08 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Trapping conformational States along ligand-binding dynamics of Peptide deformylase: the impact of induced fit on enzyme catalysis.
Plos Biol., 9, 2011
|
|
2MGV
 | | NMR structure of PASTA domain of PonA2 from Mycobacterium tuberculosis | | Descriptor: | Bifunctional membrane-associated penicillin-binding protein 1A/1B ponA2 | | Authors: | Calvanese, L, Falcigno, L, Maglione, C, Marasco, D, Ruggiero, A, Squeglia, F, Berisio, R, D'Auria, G. | | Deposit date: | 2013-11-11 | | Release date: | 2013-12-25 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Structural and binding properties of the PASTA domain of PonA2, a key penicillin binding protein from Mycobacterium tuberculosis.
Biopolymers, 101, 2014
|
|
7QVS
 | | Pseudomonas aeruginosa nicotinamide adenine dinucleotide kinase (NADK) structure in complex with NADP | | Descriptor: | NAD kinase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PHOSPHATE ION | | Authors: | Rahimova, R, Gelin, M, Labesse, G, Lionne, C. | | Deposit date: | 2022-01-23 | | Release date: | 2022-09-14 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structure-based design, synthesis and biological evaluation of a NAD + analogue targeting Pseudomonas aeruginosa NAD kinase.
Febs J., 290, 2023
|
|
1SWM
 | | X-RAY CRYSTAL STRUCTURE OF THE FERRIC SPERM WHALE MYOGLOBIN: IMIDAZOLE COMPLEX AT 2.0 ANGSTROMS RESOLUTION | | Descriptor: | AZIDE ION, MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE, ... | | Authors: | Rizzi, M, Ascenzi, P, Coda, A, Brunori, M, Bolognesi, M. | | Deposit date: | 1992-03-03 | | Release date: | 1994-01-31 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | X-ray crystal structure of the ferric sperm whale myoglobin: imidazole complex at 2.0 A resolution.
J.Mol.Biol., 217, 1991
|
|
7ZF2
 | | Protomeric substructure from an octameric assembly of M. tuberculosis RNA polymerase in complex with sigma-b initiation factor | | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | Authors: | Trapani, S, Bron, P, Lai Kee Him, J, Brodolin, K, Morichaud, Z, Vishwakarma, R. | | Deposit date: | 2022-03-31 | | Release date: | 2023-02-08 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.86 Å) | | Cite: | Structural basis of the mycobacterial stress-response RNA polymerase auto-inhibition via oligomerization.
Nat Commun, 14, 2023
|
|
7Z8Q
 | | Cryo-EM structure of Mycobacterium tuberculosis RNA polymerase core | | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | Authors: | Brodolin, K. | | Deposit date: | 2022-03-18 | | Release date: | 2023-02-08 | | Method: | ELECTRON MICROSCOPY (4.08 Å) | | Cite: | Structural basis of the mycobacterial stress-response RNA polymerase auto-inhibition via oligomerization
Nat Commun, 14, 2023
|
|
5CR7
 | |
