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6PLK
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BU of 6plk by Molmil
Crystal structure of ZIKV-116 Fab in complex with ZIKV envelope DIII
Descriptor: Env, ZIKV-116 heavy chain, ZIKV-116 light chain
Authors:Zhao, H, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2019-07-01
Release date:2019-11-20
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Mechanism of differential Zika and dengue virus neutralization by a public antibody lineage targeting the DIII lateral ridge.
J.Exp.Med., 217, 2020
7N1H
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BU of 7n1h by Molmil
CryoEM structure of Venezuelan equine encephalitis virus VLP in complex with the LDLRAD3 receptor
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Capsid, ...
Authors:Basore, K, Nelson, C.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2021-05-27
Release date:2021-10-13
Last modified:2021-11-10
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Structure of Venezuelan equine encephalitis virus in complex with the LDLRAD3 receptor.
Nature, 598, 2021
7N1I
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BU of 7n1i by Molmil
CryoEM structure of Venezuelan equine encephalitis virus VLP
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Capsid, E1 envelope glycoprotein, ...
Authors:Basore, K, Nelson, C.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2021-05-27
Release date:2021-10-13
Last modified:2021-11-10
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structure of Venezuelan equine encephalitis virus in complex with the LDLRAD3 receptor.
Nature, 598, 2021
6C74
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BU of 6c74 by Molmil
Crystal Structure of Murine CD300lf in complex with phosphocholine
Descriptor: CALCIUM ION, CMRF35-like molecule-1, PHOSPHOCHOLINE
Authors:Nelson, C.A, Fremont, D.H.
Deposit date:2018-01-19
Release date:2018-09-12
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.358 Å)
Cite:Structural basis for murine norovirus engagement of bile acids and the CD300lf receptor.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6C6Q
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BU of 6c6q by Molmil
Crystal Structure of the Murine Norovirus VP1 P Domain in complex with the CD300lf Receptor
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, CMRF35-like molecule 1, ...
Authors:Nelson, C.A, Fremont, D.H.
Deposit date:2018-01-19
Release date:2018-09-12
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for murine norovirus engagement of bile acids and the CD300lf receptor.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
4OII
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BU of 4oii by Molmil
West Nile Virus NS1 in complex with neutralizing 22NS1 antibody Fab
Descriptor: Heavy Chain of Fab fragment of 22NS1 Antibody, Light Chain of Fab fragment of 22NS1 Antibody, NON-STRUCTURAL PROTEIN NS1
Authors:Edeling, M.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2014-01-19
Release date:2014-03-05
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis of Flavivirus NS1 assembly and antibody recognition.
Proc.Natl.Acad.Sci.USA, 111, 2014
4PDC
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BU of 4pdc by Molmil
Crystal structure of Cowpox virus CPXV018 (OMCP) bound to human NKG2D
Descriptor: CPXV018 protein, NKG2-D type II integral membrane protein
Authors:Lazear, E, Nelson, C.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2014-04-17
Release date:2014-05-21
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.991 Å)
Cite:Structural basis of cowpox evasion of NKG2D immunosurveillance
Biorxiv, 2019
4OIE
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BU of 4oie by Molmil
West Nile Virus Non-structural Protein NS1
Descriptor: GLYCEROL, NON-STRUCTURAL PROTEIN NS1
Authors:Edeling, M.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2014-01-19
Release date:2014-03-05
Last modified:2014-04-23
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural basis of Flavivirus NS1 assembly and antibody recognition.
Proc.Natl.Acad.Sci.USA, 111, 2014
4OIG
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BU of 4oig by Molmil
Dengue Virus Non-structural Protein NS1
Descriptor: Non-structural protein 1, NS1, SULFATE ION
Authors:Edeling, M.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2014-01-19
Release date:2014-03-05
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:Structural basis of Flavivirus NS1 assembly and antibody recognition.
Proc.Natl.Acad.Sci.USA, 111, 2014
2HG0
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BU of 2hg0 by Molmil
Structure of the West Nile Virus envelope glycoprotein
Descriptor: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein
Authors:Nybakken, G.E, Nelson, C.A, Chen, B.R, Diamond, M.S, Fremont, D.H.
Deposit date:2006-06-26
Release date:2006-11-07
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of the West Nile virus envelope glycoprotein.
J.Virol., 80, 2006
2FWO
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BU of 2fwo by Molmil
MHC Class I H-2Kd heavy chain in complex with beta-2microglobulin and peptide derived from influenza nucleoprotein
Descriptor: Beta-2-microglobulin, H-2 class I histocompatibility antigen, K-D alpha chain, ...
Authors:Mitaksov, V, Fremont, D.H.
Deposit date:2006-02-02
Release date:2006-02-21
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Definition of the H-2Kd Peptide-binding Motif.
J.Biol.Chem., 281, 2006
2GRK
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BU of 2grk by Molmil
Crystal structure of ectromelia virus EVM1 chemokine binding protein
Descriptor: EVM001
Authors:Arnold, P.L, Fremont, D.H.
Deposit date:2006-04-24
Release date:2006-05-09
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural determinants of chemokine binding by an ectromelia virus-encoded decoy receptor.
J.Virol., 80, 2006
7K9K
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BU of 7k9k by Molmil
SARS-CoV-2 Spike RBD in complex with neutralizing Fab 2H04 (local refinement)
Descriptor: 2H04 heavy chain, 2H04 light chain, Spike protein S1, ...
Authors:Errico, J.M, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2020-09-29
Release date:2021-09-29
Last modified:2021-11-10
Method:ELECTRON MICROSCOPY (3.14 Å)
Cite:Structural mechanism of SARS-CoV-2 neutralization by two murine antibodies targeting the RBD.
Cell Rep, 37, 2021
7K9H
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BU of 7k9h by Molmil
SARS-CoV-2 Spike in complex with neutralizing Fab 2B04 (one up, two down conformation)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2B04 heavy chain, ...
Authors:Errico, J.M, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2020-09-29
Release date:2021-09-29
Last modified:2021-11-10
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural mechanism of SARS-CoV-2 neutralization by two murine antibodies targeting the RBD.
Cell Rep, 37, 2021
7K9I
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BU of 7k9i by Molmil
SARS-CoV-2 Spike RBD in complex with neutralizing Fab 2B04 (local refinement)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2B04 heavy chain, 2B04 light chain, ...
Authors:Errico, J.M, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2020-09-29
Release date:2021-09-29
Last modified:2021-11-10
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural mechanism of SARS-CoV-2 neutralization by two murine antibodies targeting the RBD.
Cell Rep, 37, 2021
7K9J
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BU of 7k9j by Molmil
SARS-CoV-2 Spike in complex with neutralizing Fab 2H04 (three down conformation)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2H04 heavy chain, ...
Authors:Errico, J.M, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2020-09-29
Release date:2021-09-29
Last modified:2021-11-10
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural mechanism of SARS-CoV-2 neutralization by two murine antibodies targeting the RBD.
Cell Rep, 37, 2021
7KYL
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BU of 7kyl by Molmil
Powassan virus Envelope protein DIII in complex with neutralizing Fab POWV-80
Descriptor: CHLORIDE ION, Envelope protein domain III, POWV-80 Fab heavy chain, ...
Authors:Errico, J.M, Nelson, C.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2020-12-08
Release date:2021-04-07
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:Broadly neutralizing monoclonal antibodies protect against multiple tick-borne flaviviruses.
J.Exp.Med., 218, 2021
3IXY
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BU of 3ixy by Molmil
The pseudo-atomic structure of dengue immature virus in complex with Fab fragments of the anti-fusion loop antibody E53
Descriptor: E53 Fab Fragment (chain H), E53 Fab Fragment (chain L), Envelope protein E, ...
Authors:Cherrier, M.V, Kaufmann, B, Nybakken, G.E, Lok, S.M, Warren, J.T, Nelson, C.A, Kostyuchenko, V.A, Holdaway, H.A, Chipman, P.R, Kuhn, R.J, Diamond, M.S, Rossmann, M.G, Fremont, D.H.
Deposit date:2009-02-26
Release date:2009-10-27
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (23 Å)
Cite:Structural basis for the preferential recognition of immature flaviviruses by a fusion-loop antibody
Embo J., 28, 2009
3IRC
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BU of 3irc by Molmil
Crystal structure analysis of dengue-1 envelope protein domain III
Descriptor: ENVELOPE PROTEIN, SULFATE ION
Authors:Nelson, C.A, Kim, T, Warren, J.T, Chruszcz, M, Minor, W, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2009-08-21
Release date:2009-09-29
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal Structure Analysis of the Dengue-1 Envelope Protein Domain III
To be Published
3I50
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BU of 3i50 by Molmil
Crystal structure of the West Nile Virus envelope glycoprotein in complex with the E53 antibody Fab
Descriptor: Envelope glycoprotein, murine heavy chain (IgG3) of E53 monoclonal antibody Fab, murine kappa light chain of E53 monoclonal antibody Fab
Authors:Nybakken, G.E, Warren, J.T, Chen, B.R, Nelson, C.A, Fremont, D.H.
Deposit date:2009-07-03
Release date:2009-10-27
Last modified:2013-09-25
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis for the preferential recognition of immature flaviviruses by a fusion-loop antibody.
Embo J., 28, 2009
3HXO
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BU of 3hxo by Molmil
Crystal Structure of Von Willebrand Factor (VWF) A1 Domain in Complex with DNA Aptamer ARC1172, an Inhibitor of VWF-Platelet Binding
Descriptor: Aptamer ARC1172, von Willebrand factor
Authors:Huang, R.H, Sadler, J.E, Fremont, D.H, Diener, J.L, Schaub, R.G.
Deposit date:2009-06-21
Release date:2009-11-17
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A structural explanation for the antithrombotic activity of ARC1172, a DNA aptamer that binds von Willebrand factor domain A1.
Structure, 17, 2009
3IXX
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BU of 3ixx by Molmil
The pseudo-atomic structure of West Nile immature virus in complex with Fab fragments of the anti-fusion loop antibody E53
Descriptor: E53 Fab Fragment (chain H), E53 Fab Fragment (chain L), Envelope protein E, ...
Authors:Cherrier, M.V, Kaufmann, B, Nybakken, G.E, Lok, S.M, Warren, J.T, Nelson, C.A, Kostyuchenko, V.A, Holdaway, H.A, Chipman, P.R, Kuhn, R.J, Diamond, M.S, Rossmann, M.G, Fremont, D.H.
Deposit date:2009-02-26
Release date:2009-10-27
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (15 Å)
Cite:Structural basis for the preferential recognition of immature flaviviruses by a fusion-loop antibody
Embo J., 28, 2009
3HXQ
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BU of 3hxq by Molmil
Crystal Structure of Von Willebrand Factor (VWF) A1 Domain in Complex with DNA Aptamer ARC1172, an Inhibitor of VWF-Platelet Binding
Descriptor: Aptamer ARC1172, von Willebrand Factor
Authors:Huang, R.H, Sadler, J.E, Fremont, D.H, Diener, J.L, Schaub, R.G.
Deposit date:2009-06-21
Release date:2009-11-17
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.694 Å)
Cite:A structural explanation for the antithrombotic activity of ARC1172, a DNA aptamer that binds von Willebrand factor domain A1.
Structure, 17, 2009
7JX6
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BU of 7jx6 by Molmil
STRUCTURE OF THE SARS-CoV-2 ORF8 ENCODED ACCESSORY PROTEIN
Descriptor: ORF8 protein, SODIUM ION
Authors:Hall, P.D, Nelson, C.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2020-08-26
Release date:2020-09-23
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:Crystal Structure of the SARS-CoV-2 ORF8 Protein
To Be Published
4FFZ
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BU of 4ffz by Molmil
Crystal Structure of DENV1-E111 fab fragment bound to DENV-1 DIII (Western Pacific-74 strain).
Descriptor: DENV1-E111 fab fragment (heavy chain), DENV1-E111 fab fragment (light chain), Envelope protein E
Authors:Austin, S.K, Nelson, C.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2012-06-01
Release date:2012-06-27
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Structural Basis of Differential Neutralization of DENV-1 Genotypes by an Antibody that Recognizes a Cryptic Epitope.
Plos Pathog., 8, 2012

226707

数据于2024-10-30公开中

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