4PDC

Crystal structure of Cowpox virus CPXV018 (OMCP) bound to human NKG2D

Summary for 4PDC

Entry DOI	10.2210/pdb4pdc/pdb
Related	1HYR 1JSK 1KCG 1MPU 4FFE
Descriptor	NKG2-D type II integral membrane protein, CPXV018 protein (3 entities in total)
Functional Keywords	secreted viral protein, immune evasion, orthopoxvirus, mhc-like fold, nk cell receptor ligand, structural genomics, center for structural genomics of infectious diseases, csgid, immune system-viral protein complex, immune system/viral protein
Biological source	Homo sapiens (Human) More
Total number of polymer chains	6
Total formula weight	92772.18
Authors	Lazear, E.,Nelson, C.A.,Fremont, D.H.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2014-04-17, release date: 2014-05-21, Last modification date: 2023-09-27)
Primary citation	Lazear, E.,Sun, M.M.,Wang, X.,Geurs, T.L.,Nelson, C.A.,Campbell, J.A.,Lippold, D.,Krupnick, A.S.,Davis, R.S.,Carayannopoulos, L.N.,French, A.R.,Fremont, D.H. Structural basis of cowpox evasion of NKG2D immunosurveillance Biorxiv, 2019 Cited by DOI: 10.1101/796862 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.991 Å)

Structure validation