4L9B
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![BU of 4l9b by Molmil](/molmil-images/mine/4l9b) | Structure of native RBP from lactococcal phage 1358 (CsI derivative) | Descriptor: | CESIUM ION, Receptor Binding Protein | Authors: | Farenc, C, Spinelli, S, Bebeacua, C, Tremblay, D, Orlov, I, Blangy, S, Klaholz, B.P, Moineau, S, Cambillau, C. | Deposit date: | 2013-06-18 | Release date: | 2014-04-30 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | A Virulent Siphophage CyoEM Structure and Host Recognition and Infection Mechanism To be Published
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3FE6
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![BU of 3fe6 by Molmil](/molmil-images/mine/3fe6) | Crystal structure of a pheromone binding protein from Apis mellifera with a serendipitous ligand at pH 5.5 | Descriptor: | (20S)-20-methyldotetracontane, CHLORIDE ION, GLYCEROL, ... | Authors: | Pesenti, M.E, Spinelli, S, Bezirard, V, Briand, L, Pernollet, J.C, Tegoni, M, Cambillau, C. | Deposit date: | 2008-11-27 | Release date: | 2009-12-01 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Queen bee pheromone binding protein pH induced domain-swapping favors pheromone release To be Published
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3FE9
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![BU of 3fe9 by Molmil](/molmil-images/mine/3fe9) | Crystal structure of a pheromone binding protein from Apis mellifera with a serendipitous ligand soaked at pH 7.0 | Descriptor: | (20S)-20-methyldotetracontane, CHLORIDE ION, Pheromone-binding protein ASP1 | Authors: | Pesenti, M.E, Spinelli, S, Bezirard, V, Briand, L, Pernollet, J.C, Tegoni, M, Cambillau, C. | Deposit date: | 2008-11-28 | Release date: | 2009-12-01 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Queen bee pheromone binding protein pH induced domain-swapping favors pheromone release To be Published
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3FE8
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![BU of 3fe8 by Molmil](/molmil-images/mine/3fe8) | Crystal structure of a pheromone binding protein from Apis mellifera with a serendipitous ligand soaked at pH 4.0 | Descriptor: | (20S)-20-methyldotetracontane, CHLORIDE ION, GLYCEROL, ... | Authors: | Pesenti, M.E, Spinelli, S, Bezirard, V, Briand, L, Pernollet, J.C, Tegoni, M, Cambillau, C. | Deposit date: | 2008-11-28 | Release date: | 2009-12-01 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Queen bee pheromone binding protein pH induced domain-swapping favors pheromone release To be Published
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1GT4
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![BU of 1gt4 by Molmil](/molmil-images/mine/1gt4) | Complex of Bovine Odorant Binding Protein with undecanal | Descriptor: | ODORANT-BINDING PROTEIN, UNDECANAL | Authors: | Vincent, F, Ramoni, R, Spinelli, S, Grolli, S, Conti, V, Cambillau, C, Tegoni, M. | Deposit date: | 2002-01-10 | Release date: | 2003-10-03 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal Structures of Bovine Odorant-Binding Protein in Complex with Odorant Molecules. Eur.J.Biochem., 271, 2004
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1GT5
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![BU of 1gt5 by Molmil](/molmil-images/mine/1gt5) | Complexe of Bovine Odorant Binding Protein with benzophenone | Descriptor: | DIPHENYLMETHANONE, ODORANT-BINDING PROTEIN | Authors: | Vincent, F, Ramoni, R, Spinelli, S, Grolli, S, Conti, V, Cambillau, C, Tegoni, M. | Deposit date: | 2002-01-10 | Release date: | 2003-10-03 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.08 Å) | Cite: | Crystal Structures of Bovine Odorant-Binding Protein in Complex with Odorant Molecules. Eur.J.Biochem., 271, 2004
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1GT3
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![BU of 1gt3 by Molmil](/molmil-images/mine/1gt3) | Complex of Bovine Odorant Binding Protein with dihydromyrcenol | Descriptor: | (3S)-1-octen-3-ol, 2,6-DIMETHYL-7-OCTEN-2-OL, ODORANT-BINDING PROTEIN | Authors: | Vincent, F, Ramoni, R, Spinelli, S, Grolli, S, Conti, V, Cambillau, C, Tegoni, M. | Deposit date: | 2002-01-10 | Release date: | 2003-10-03 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal Structures of Bovine Odorant-Binding Protein in Complex with Odorant Molecules. Eur.J.Biochem., 271, 2004
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1GT1
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![BU of 1gt1 by Molmil](/molmil-images/mine/1gt1) | Complex of Bovine Odorant Binding Protein with Aminoanthracene and pyrazine | Descriptor: | (3S)-1-octen-3-ol, 2-ISOBUTYL-3-METHOXYPYRAZINE, ANTHRACEN-1-YLAMINE, ... | Authors: | Vincent, F, Ramoni, R, Spinelli, S, Grolli, S, Conti, V, Cambillau, C, Tegoni, M. | Deposit date: | 2002-01-10 | Release date: | 2003-10-03 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.71 Å) | Cite: | Crystal Structures of Bovine Odorant-Binding Protein in Complex with Odorant Molecules. Eur.J.Biochem., 271, 2004
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2H8V
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![BU of 2h8v by Molmil](/molmil-images/mine/2h8v) | Structure of empty Pheromone Binding Protein ASP1 from the Honeybee Apis mellifera L | Descriptor: | CHLORIDE ION, GLYCEROL, Pheromone-binding protein ASP1, ... | Authors: | Pesenti, M.E, Spinelli, S, Briand, L, Pernollet, J.-C, Cambillau, C, Tegoni, M. | Deposit date: | 2006-06-08 | Release date: | 2007-12-11 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Conformational Changes of the Pheromone Binding Protein ASP1 from the Honeybee Apis mellifera L upon Ligand Binding To be Published
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2EU1
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![BU of 2eu1 by Molmil](/molmil-images/mine/2eu1) | Crystal structure of the chaperonin GroEL-E461K | Descriptor: | GROEL | Authors: | Cabo-Bilbao, A, Spinelli, S, Sot, B, Agirre, J, Mechaly, A.E, Muga, A, Guerin, D.M.A. | Deposit date: | 2005-10-28 | Release date: | 2006-08-29 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (3.29 Å) | Cite: | Crystal structure of the temperature-sensitive and allosteric-defective chaperonin GroEL(E461K). J.Struct.Biol., 155, 2006
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3HG0
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![BU of 3hg0 by Molmil](/molmil-images/mine/3hg0) | Crystal structure of a DARPin in complex with ORF49 from Lactococcal phage TP901-1 | Descriptor: | Baseplate protein, Designed Ankyrin Repeat Protein (DARPin) 20 | Authors: | Veesler, D, Dreier, B, Blangy, S, Lichiere, J, Tremblay, D, Moineau, S, Spinelli, S, Tegoni, M, Pluckthun, A, Campanacci, V, Cambillau, C. | Deposit date: | 2009-05-13 | Release date: | 2009-09-08 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure and function of a DARPin neutralizing inhibitor of lactococcal phage TP901-1: comparison of DARPin and camelid VHH binding mode. J.Biol.Chem., 284, 2009
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4Y7M
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![BU of 4y7m by Molmil](/molmil-images/mine/4y7m) | T6SS protein TssM C-terminal domain (835-1129) from EAEC | Descriptor: | Hi113 protein, SULFATE ION, Type VI secretion protein IcmF | Authors: | Nguyen, V.S, Spinelli, S, Durand, E, Roussel, A, Cambillau, C. | Deposit date: | 2015-02-15 | Release date: | 2015-08-05 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | Biogenesis and structure of a type VI secretion membrane core complex. Nature, 523, 2015
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4YO3
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![BU of 4yo3 by Molmil](/molmil-images/mine/4yo3) | Enteroaggregative Escherichia Coli TssA N-terminal fragment | Descriptor: | TssA | Authors: | Durand, E, Zoued, A, Spinelli, S, Douzi, B, Brunet, Y.R, Bebeacua, C, Legrand, P, Journet, L, Mignot, T, Cambillau, C, Cascales, E. | Deposit date: | 2015-03-11 | Release date: | 2016-02-17 | Last modified: | 2017-08-30 | Method: | X-RAY DIFFRACTION (3.37 Å) | Cite: | Priming and polymerization of a bacterial contractile tail structure. Nature, 531, 2016
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4Y7O
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![BU of 4y7o by Molmil](/molmil-images/mine/4y7o) | T6SS protein TssM C-terminal domain (869-1107) from EAEC | Descriptor: | Type VI secretion protein IcmF, Type VI secretion system protein VasD, ZINC ION | Authors: | Nguyen, V.S, Spinelli, S, Durand, E, Roussel, A, Cambillau, C. | Deposit date: | 2015-02-15 | Release date: | 2015-08-05 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.24 Å) | Cite: | Biogenesis and structure of a type VI secretion membrane core complex. Nature, 523, 2015
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4YO5
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![BU of 4yo5 by Molmil](/molmil-images/mine/4yo5) | EAEC T6SS TssA-Cterminus | Descriptor: | TssA | Authors: | Durand, E, Zoued, A, Spinelli, S, Douzi, B, Brunet, Y.R, Bebeacua, C, Legrand, P, Journet, L, Mignot, T, Cambillau, C, Cascales, E. | Deposit date: | 2015-03-11 | Release date: | 2016-02-17 | Last modified: | 2017-06-14 | Method: | X-RAY DIFFRACTION (3.35 Å) | Cite: | Priming and polymerization of a bacterial contractile tail structure. Nature, 531, 2016
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4Y7L
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![BU of 4y7l by Molmil](/molmil-images/mine/4y7l) | T6SS protein TssM C-terminal domain (869-1107) from EAEC | Descriptor: | GLYCEROL, Type VI secretion protein IcmF, ZINC ION | Authors: | Nguyen, V.S, Spinelli, S, Durand, E, Roussel, A, Cambillau, C. | Deposit date: | 2015-02-15 | Release date: | 2015-08-05 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.51 Å) | Cite: | Biogenesis and structure of a type VI secretion membrane core complex. Nature, 523, 2015
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4QGY
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![BU of 4qgy by Molmil](/molmil-images/mine/4qgy) | Camelid (llama) nanobody n25 (VHH) against type 6 secretion system TssM protein | Descriptor: | nanobody n25, VH domain | Authors: | Nguyen, V.S, Desmyter, A, Le, T.T.H, Durand, E, Kellenberger, C, Douzi, B, Spinelli, S, Cascales, E, Cambillau, C, Roussel, A. | Deposit date: | 2014-05-26 | Release date: | 2015-04-08 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.38 Å) | Cite: | Inhibition of Type VI Secretion by an Anti-TssM Llama Nanobody. Plos One, 10, 2015
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4QLR
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![BU of 4qlr by Molmil](/molmil-images/mine/4qlr) | Llama nanobody n02 raised against EAEC T6SS TssM | Descriptor: | Llama nanobody n02 VH domain | Authors: | Nguyen, V.S, Desmyter, A, Le, T.T.H, Durand, E, Kellenberger, C, Douzi, B, Spinelli, S, Cascales, E, Cambillau, C, Roussel, A. | Deposit date: | 2014-06-13 | Release date: | 2015-04-08 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Inhibition of Type VI Secretion by an Anti-TssM Llama Nanobody. Plos One, 10, 2015
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4R90
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![BU of 4r90 by Molmil](/molmil-images/mine/4r90) | Anti CD70 Llama glama Fab 27B3 | Descriptor: | Anti CD70 Llama glama Fab 27B3 Heavy chain, Anti CD70 Llama glama Fab 27B3 Light chain, CALCIUM ION, ... | Authors: | Klarenbeek, A, El Mazouari, K, Desmyter, A, Blanchetot, C, Hultberg, A, Roovers, R.C, Cambillau, C, Spinelli, S, Del-Favero, J, Verrips, T, de Haard, H, Achour, I. | Deposit date: | 2014-09-03 | Release date: | 2015-06-24 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.746 Å) | Cite: | Camelid Ig V genes reveal significant human homology not seen in therapeutic target genes, providing for a powerful therapeutic antibody platform. MAbs, 7, 2015
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4R96
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![BU of 4r96 by Molmil](/molmil-images/mine/4r96) | Structure of a Llama Glama Fab 48A2 against human cMet | Descriptor: | Llama glama Fab 48A2 against human cMet H chain, Llama glama Fab 48A2 against human cMet L chain | Authors: | Klarenbeek, A, El Mazouari, K, Desmyter, A, Blanchetot, C, Hultberg, A, Roovers, R.C, Cambillau, C, Spinelli, S, Del-Favero, J, Verrips, T, de Haard, H, Achour, I. | Deposit date: | 2014-09-03 | Release date: | 2015-06-24 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.31 Å) | Cite: | Camelid Ig V genes reveal significant human homology not seen in therapeutic target genes, providing for a powerful therapeutic antibody platform. MAbs, 7, 2015
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2A9M
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![BU of 2a9m by Molmil](/molmil-images/mine/2a9m) | |
4O9H
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![BU of 4o9h by Molmil](/molmil-images/mine/4o9h) | Structure of Interleukin-6 in complex with a Camelid Fab fragment | Descriptor: | Heavy Chain of the Camelid Fab fragment 61H7, Interleukin-6, Light Chain of the Camelid Fab fragment 61H7 | Authors: | Klarenbeek, A, Blanchetot, C, Schragel, G, Sadi, A.S, Ongenae, N, Hemrika, W, Wijdenes, J, Spinelli, S, Desmyter, A, Cambillau, C, Hultberg, A, Kretz-rommel, A, Dreier, T, De haard, H.J.W, Roovers, R.C. | Deposit date: | 2014-01-02 | Release date: | 2015-04-15 | Last modified: | 2015-04-29 | Method: | X-RAY DIFFRACTION (2.42 Å) | Cite: | Combining residues of naturally-occurring Camelid somatic affinity variants yields ultra-potent human therapeutic IL-6 antibodies To be Published
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4NNZ
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![BU of 4nnz by Molmil](/molmil-images/mine/4nnz) | |
2A9N
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![BU of 2a9n by Molmil](/molmil-images/mine/2a9n) | A Mutation Designed to Alter Crystal Packing Permits Structural Analysis of a Tight-binding Fluorescein-scFv complex | Descriptor: | 4-(2,7-DIFLUORO-6-HYDROXY-3-OXO-3H-XANTHEN-9-YL)ISOPHTHALIC ACID, fluorescein-scfv | Authors: | Cambillau, C, Spinelli, S, Honegger, A, Pluckthun, A. | Deposit date: | 2005-07-12 | Release date: | 2005-10-25 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | A mutation designed to alter crystal packing permits structural analysis of a tight-binding fluorescein-scFv complex. Protein Sci., 14, 2005
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1U0Q
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![BU of 1u0q by Molmil](/molmil-images/mine/1u0q) | |