1RGQ
 
 | | M9A HCV Protease complex with pentapeptide keto-amide inhibitor | | Descriptor: | N-(PYRAZIN-2-YLCARBONYL)LEUCYLISOLEUCYL-N~1~-{1-[2-({1-CARBOXY-2-[4-(PHOSPHONOOXY)PHENYL]ETHYL}AMINO)-1,1-DIHYDROXY-2-OXOETHYL]BUT-3-ENYL}-3-CYCLOHEXYLALANINAMIDE, NS3 Protease, NS4A peptide, ... | | Authors: | Liu, Y, Stoll, V.S, Richardson, P.L, Saldivar, A, Klaus, J.L, Molla, A, Kohlbrenner, W, Kati, W.M. | | Deposit date: | 2003-11-12 | | Release date: | 2004-10-19 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Hepatitis C NS3 protease inhibition by peptidyl-alpha-ketoamide inhibitors: kinetic mechanism and structure.
Arch.Biochem.Biophys., 421, 2004
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5T1G
 | | chromo shadow domain of CBX1 in complex with a histone peptide | | Descriptor: | Chromobox protein homolog 1, Histone H3.1, UNKNOWN ATOM OR ION | | Authors: | Liu, Y, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | | Deposit date: | 2016-08-19 | | Release date: | 2016-09-14 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | chromo shadow domain of CBX1 in complex with a histone peptide
To Be Published
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5UK2
 | | CryoEM structure of an influenza virus receptor-binding site antibody-antigen interface - Class 4 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, ... | | Authors: | Liu, Y, Pan, J, Caradonna, T, Jenni, S, Raymond, D.D, Schmidt, A.G, Harrison, S.C, Grigorieff, N. | | Deposit date: | 2017-01-19 | | Release date: | 2017-05-31 | | Last modified: | 2020-07-29 | | Method: | ELECTRON MICROSCOPY (4.8 Å) | | Cite: | CryoEM Structure of an Influenza Virus Receptor-Binding Site Antibody-Antigen Interface.
J. Mol. Biol., 429, 2017
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5UJZ
 | | CryoEM structure of an influenza virus receptor-binding site antibody-antigen interface - Class 1 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, ... | | Authors: | Liu, Y, Pan, J, Caradonna, T, Jenni, S, Raymond, D.D, Schmidt, A.G, Harrison, S.C, Grigorieff, N. | | Deposit date: | 2017-01-19 | | Release date: | 2017-05-31 | | Last modified: | 2020-07-29 | | Method: | ELECTRON MICROSCOPY (4.8 Å) | | Cite: | CryoEM Structure of an Influenza Virus Receptor-Binding Site Antibody-Antigen Interface.
J. Mol. Biol., 429, 2017
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5UK0
 | | CryoEM structure of an influenza virus receptor-binding site antibody-antigen interface - Class 2 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, ... | | Authors: | Liu, Y, Pan, J, Caradonna, T, Jenni, S, Raymond, D.D, Schmidt, A.G, Harrison, S.C, Grigorieff, N. | | Deposit date: | 2017-01-19 | | Release date: | 2017-05-31 | | Last modified: | 2020-07-29 | | Method: | ELECTRON MICROSCOPY (4.8 Å) | | Cite: | CryoEM Structure of an Influenza Virus Receptor-Binding Site Antibody-Antigen Interface.
J. Mol. Biol., 429, 2017
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5UZA
 | | Adenine riboswitch aptamer domain labelled with iodo-uridine by position-selective labelling of RNA (PLOR) | | Descriptor: | ADENINE, MAGNESIUM ION, RNA (71-MER) | | Authors: | Liu, Y, Stagno, J.R, Wang, Y.-X. | | Deposit date: | 2017-02-25 | | Release date: | 2018-02-28 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (2.22 Å) | | Cite: | Incorporation of isotopic, fluorescent, and heavy-atom-modified nucleotides into RNAs by position-selective labeling of RNA.
Nat Protoc, 13, 2018
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5UK1
 | | CryoEM structure of an influenza virus receptor-binding site antibody-antigen interface - Class 3 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, ... | | Authors: | Liu, Y, Pan, J, Caradonna, T, Jenni, S, Raymond, D.D, Schmidt, A.G, Harrison, S.C, Grigorieff, N. | | Deposit date: | 2017-01-19 | | Release date: | 2017-05-31 | | Last modified: | 2020-07-29 | | Method: | ELECTRON MICROSCOPY (4.8 Å) | | Cite: | CryoEM Structure of an Influenza Virus Receptor-Binding Site Antibody-Antigen Interface.
J. Mol. Biol., 429, 2017
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3SEC
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8DWC
 | | CryoEM structure of Gq-coupled MRGPRX1 with peptide agonist BAM8-22 | | Descriptor: | Gs-mini-Gq chimera, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | Authors: | Liu, Y, Cao, C, Fay, J.F, Roth, B.L. | | Deposit date: | 2022-08-01 | | Release date: | 2022-11-02 | | Last modified: | 2023-04-12 | | Method: | ELECTRON MICROSCOPY (2.87 Å) | | Cite: | Ligand recognition and allosteric modulation of the human MRGPRX1 receptor.
Nat.Chem.Biol., 19, 2023
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8DWH
 | | CryoEM structure of Gq-coupled MRGPRX1 with ligand Compound-16 | | Descriptor: | Gs-mini-Gq chimera, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | Authors: | Liu, Y, Cao, C, Fay, J.F, Roth, B.L. | | Deposit date: | 2022-08-01 | | Release date: | 2022-11-02 | | Last modified: | 2023-04-12 | | Method: | ELECTRON MICROSCOPY (3.25 Å) | | Cite: | Ligand recognition and allosteric modulation of the human MRGPRX1 receptor.
Nat.Chem.Biol., 19, 2023
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8DWG
 | | CryoEM structure of Gq-coupled MRGPRX1 with peptide ligand BAM8-22 and positive allosteric modulator ML382 | | Descriptor: | 2-[(cyclopropanesulfonyl)amino]-N-(2-ethoxyphenyl)benzamide, Gs-mini-Gq chimera, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | Authors: | Liu, Y, Cao, C, Fay, J.F, Roth, B.L. | | Deposit date: | 2022-08-01 | | Release date: | 2022-11-02 | | Last modified: | 2023-04-12 | | Method: | ELECTRON MICROSCOPY (2.71 Å) | | Cite: | Ligand recognition and allosteric modulation of the human MRGPRX1 receptor.
Nat.Chem.Biol., 19, 2023
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8WH5
 | | Structure of DDM1-nucleosome complex in the apo state | | Descriptor: | ATP-dependent DNA helicase DDM1, DNA (antisense strand), DNA (sense strand), ... | | Authors: | Liu, Y, Zhang, Z, Du, J. | | Deposit date: | 2023-09-22 | | Release date: | 2024-04-17 | | Method: | ELECTRON MICROSCOPY (3.58 Å) | | Cite: | Molecular basis of chromatin remodelling by DDM1 involved in plant DNA methylation.
Nat.Plants, 10, 2024
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8WH8
 | | Structure of DDM1-nucleosome complex in ADP state | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent DNA helicase DDM1, DNA (antisense strand), ... | | Authors: | Liu, Y, Zhang, Z, Du, J. | | Deposit date: | 2023-09-22 | | Release date: | 2024-04-17 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Molecular basis of chromatin remodelling by DDM1 involved in plant DNA methylation.
Nat.Plants, 10, 2024
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8WHB
 | | Structure of nucleosome core particle of Arabidopsis thaliana | | Descriptor: | DNA (antisense strand), DNA (sense strand), Histone H2A.6, ... | | Authors: | Liu, Y, Zhang, Z, Du, J. | | Deposit date: | 2023-09-23 | | Release date: | 2024-04-17 | | Method: | ELECTRON MICROSCOPY (3.17 Å) | | Cite: | Molecular basis of chromatin remodelling by DDM1 involved in plant DNA methylation.
Nat.Plants, 10, 2024
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8WHA
 | | Structure of DDM1-nucleosome complex in the ADP-BeFx state with DDM1 bound to SHL2 and SHL-2 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent DNA helicase DDM1, BERYLLIUM TRIFLUORIDE ION, ... | | Authors: | Liu, Y, Zhang, Z, Du, J. | | Deposit date: | 2023-09-22 | | Release date: | 2024-04-17 | | Method: | ELECTRON MICROSCOPY (4.05 Å) | | Cite: | Molecular basis of chromatin remodelling by DDM1 involved in plant DNA methylation.
Nat.Plants, 10, 2024
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8WH9
 | | Structure of DDM1-nucleosome complex in ADP-BeFx state | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent DNA helicase DDM1, BERYLLIUM TRIFLUORIDE ION, ... | | Authors: | Liu, Y, Zhang, Z, Du, J. | | Deposit date: | 2023-09-22 | | Release date: | 2024-04-17 | | Method: | ELECTRON MICROSCOPY (3.31 Å) | | Cite: | Molecular basis of chromatin remodelling by DDM1 involved in plant DNA methylation.
Nat.Plants, 10, 2024
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1WQ6
 | | The tetramer structure of the nervy homolgy two (NHR2) domain of AML1-ETO is critical for AML1-ETO'S activity | | Descriptor: | AML1-ETO | | Authors: | Liu, Y, Cheney, M.D, Chruszcz, M, Lukasik, S.M, Hartman, K.L, Laue, T.M, Dauter, Z, Minor, W, Speck, N.A, Bushweller, J.H. | | Deposit date: | 2004-09-23 | | Release date: | 2005-10-04 | | Last modified: | 2022-04-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | The tetramer structure of the Nervy homology two domain, NHR2, is critical for AML1/ETO's activity
Cancer Cell, 9, 2006
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1YQE
 | | Crystal Structure of Conserved Protein of Unknown Function AF0625 | | Descriptor: | Hypothetical UPF0204 protein AF0625, PYROPHOSPHATE 2- | | Authors: | Liu, Y, Skarina, T, Dong, A, Kudritskam, M, Savchenko, A, Pai, E.F, Edwards, A, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2005-02-01 | | Release date: | 2005-03-15 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.83 Å) | | Cite: | Crystal Structure of Conserved Hypothetical Protein AF0625
To be Published
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1YXO
 | | Crystal Structure of pyridoxal phosphate biosynthetic protein PdxA PA0593 | | Descriptor: | 4-hydroxythreonine-4-phosphate dehydrogenase 1, ETHANOL, MAGNESIUM ION | | Authors: | Liu, Y, Xu, X, Dong, A, Kudritskam, M, Savchenko, A, Pai, E.F, Joachimiak, A, Edwards, A, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2005-02-22 | | Release date: | 2005-04-05 | | Last modified: | 2011-10-05 | | Method: | X-RAY DIFFRACTION (2.01 Å) | | Cite: | Crystal Structure of pyridoxal phosphate biosynthetic protein PdxA PA0593
To be Published
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3BPW
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3BK0
 | | Crystal Structure of Human Orotidine 5'-monophosphate Decarboxylase Complexed with 5-CN-UMP | | Descriptor: | 5-CYANO-URIDINE-5'-MONOPHOSPHATE, GLYCEROL, SULFATE ION, ... | | Authors: | Liu, Y, Tang, H.L, Avina, M.E.M, Kotra, L.P, Pai, E.F. | | Deposit date: | 2007-12-05 | | Release date: | 2008-11-18 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Crystal Structure of Human Orotidine 5'-monophosphate Decarboxylase Complexed with 5-CN-UMP
To be Published
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4BL6
 | | Bicaudal-D uses a parallel, homodimeric coiled coil with heterotypic registry to co-ordinate recruitment of cargos to dynein | | Descriptor: | ARGININE, PROTEIN BICAUDAL D | | Authors: | Liu, Y, Salter, H.K, Holding, A.N, Johnson, C.M, Stephens, E, Lukavsky, P.J, Walshaw, J, Bullock, S.L. | | Deposit date: | 2013-05-02 | | Release date: | 2013-06-12 | | Last modified: | 2017-07-12 | | Method: | X-RAY DIFFRACTION (2.18 Å) | | Cite: | Bicaudal-D Uses a Parallel, Homodimeric Coiled Coil with Heterotypic Registry to Coordinate Recruitment of Cargos to Dynein
Genes Dev., 27, 2013
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3BVJ
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2OQS
 | | Structure of the hDLG/SAP97 PDZ2 in complex with HPV-18 papillomavirus E6 peptide | | Descriptor: | C-terminal HPV-18 E6 peptide, Disks large homolog 1 | | Authors: | Liu, Y, Baleja, J.D, Henry, G.D, Hegde, R.S. | | Deposit date: | 2007-02-01 | | Release date: | 2007-09-04 | | Last modified: | 2023-12-27 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the hDlg/SAP97 PDZ2 domain and its mechanism of interaction with HPV-18 papillomavirus E6 protein.
Biochemistry, 46, 2007
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2P1F
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