8P9D
| Crystal structure of p63-p73 heterotetramer (tetramerisation domain) in complex with darpin 1810 A2 | Descriptor: | Darpin 1810 A2, Tumor protein 63, Tumor protein p73 | Authors: | Chaikuad, A, Strubel, A, Doetsch, V, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2023-06-05 | Release date: | 2023-11-08 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | DARPins detect the formation of hetero-tetramers of p63 and p73 in epithelial tissues and in squamous cell carcinoma. Cell Death Dis, 14, 2023
|
|
8P9C
| Crystal structure of p63-p73 heterotetramer (tetramerisation domain) in complex with darpin 1810 F11 | Descriptor: | 1,2-ETHANEDIOL, Darpin 1810 F11, Tumor protein 63, ... | Authors: | Chaikuad, A, Strubel, A, Doetsch, V, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2023-06-05 | Release date: | 2023-11-08 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | DARPins detect the formation of hetero-tetramers of p63 and p73 in epithelial tissues and in squamous cell carcinoma. Cell Death Dis, 14, 2023
|
|
8P9E
| Crystal structure of wild type p63-p73 heterotetramer (tetramerisation domain) in complex with darpin 1810 F11 | Descriptor: | Darpin 1810 F11, GLYCEROL, Isoform 2 of Tumor protein 63, ... | Authors: | Chaikuad, A, Strubel, A, Doetsch, V, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2023-06-05 | Release date: | 2023-11-08 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | DARPins detect the formation of hetero-tetramers of p63 and p73 in epithelial tissues and in squamous cell carcinoma. Cell Death Dis, 14, 2023
|
|
3SJD
| Crystal structure of S. cerevisiae Get3 with bound ADP-Mg2+ in complex with Get2 cytosolic domain | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATPase GET3, Golgi to ER traffic protein 2, ... | Authors: | Reitz, S, Wild, K, Sinning, I. | Deposit date: | 2011-06-21 | Release date: | 2011-07-13 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (4.6 Å) | Cite: | Structural basis for tail-anchored membrane protein biogenesis by the Get3-receptor complex. Science, 333, 2011
|
|
3SJA
| Crystal structure of S. cerevisiae Get3 in the open state in complex with Get1 cytosolic domain | Descriptor: | ATPase GET3, Golgi to ER traffic protein 1, PHOSPHATE ION, ... | Authors: | Reitz, S, Wild, K, Sinning, I. | Deposit date: | 2011-06-21 | Release date: | 2011-07-06 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural basis for tail-anchored membrane protein biogenesis by the Get3-receptor complex. Science, 333, 2011
|
|
3SJB
| Crystal structure of S. cerevisiae Get3 in the open state in complex with Get1 cytosolic domain | Descriptor: | ATPase GET3, Golgi to ER traffic protein 1, PHOSPHATE ION, ... | Authors: | Reitz, S, Wild, K, Sinning, I. | Deposit date: | 2011-06-21 | Release date: | 2011-07-06 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structural basis for tail-anchored membrane protein biogenesis by the Get3-receptor complex. Science, 333, 2011
|
|
3SJC
| |
5DPT
| Crystal structure of PLEKHM1 LIR-fused human GABARAPL1_2-117 | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Pleckstrin homology domain-containing family M member 1, Gamma-aminobutyric acid receptor-associated protein-like 1,Gamma-aminobutyric acid receptor-associated protein-like 1 | Authors: | Ravichandran, A.C, Suzuki, H, Dobson, R.C.J. | Deposit date: | 2015-09-14 | Release date: | 2016-09-28 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural and functional analysis of the GABARAP interaction motif (GIM). EMBO Rep., 18, 2017
|
|
7OVC
| Structure of the human UFC1 protein in complex with the UBA5 C-terminal UFC1-binding motif. | Descriptor: | Ubiquitin-fold modifier-conjugating enzyme 1, Ubiquitin-like modifier-activating enzyme 5 | Authors: | Wesch, W, Loehr, F, Rogova, N, Doetsch, V, Rogov, V.V. | Deposit date: | 2021-06-14 | Release date: | 2021-08-04 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | A Concerted Action of UBA5 C-Terminal Unstructured Regions Is Important for Transfer of Activated UFM1 to UFC1. Int J Mol Sci, 22, 2021
|
|
2MD9
| Solution Structure of an Active Site Mutant Pepitdyl Carrier Protein | Descriptor: | Tyrocidine synthase 3 | Authors: | Tufar, P, Rahighi, S, Kraas, F.I, Kirchner, D.K, Loehr, F, Henrich, E, Koepke, J, Dikic, I, Guentert, P, Marahiel, M.A, Doetsch, V. | Deposit date: | 2013-09-06 | Release date: | 2014-04-23 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Crystal Structure of a PCP/Sfp Complex Reveals the Structural Basis for Carrier Protein Posttranslational Modification. Chem.Biol., 21, 2014
|
|
2MYX
| Structure of the CUE domain of yeast Cue1 | Descriptor: | Coupling of ubiquitin conjugation to ER degradation protein 1 | Authors: | Kniss, A, Rogov, V.V, Loehr, F, Guentert, P, Doetsch, V. | Deposit date: | 2015-02-02 | Release date: | 2016-03-23 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | The CUE Domain of Cue1 Aligns Growing Ubiquitin Chains with Ubc7 for Rapid Elongation. Mol.Cell, 62, 2016
|
|
2NB1
| P63/p73 hetero-tetramerisation domain | Descriptor: | Tumor protein 63, Tumor protein p73 | Authors: | Gebel, J, Buchner, L, Loehr, F.M, Luh, L.M, Coutandin, D, Guentert, P, Doetsch, V. | Deposit date: | 2016-01-19 | Release date: | 2016-12-07 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Mechanism of TAp73 inhibition by Delta Np63 and structural basis of p63/p73 hetero-tetramerization. Cell Death Differ., 23, 2016
|
|
2MW4
| Tetramerization domain of the Ciona intestinalis p53/p73-b transcription factor protein | Descriptor: | Transcription factor protein | Authors: | Heering, J.P, Jonker, H.R.A, Loehr, F, Schwalbe, H, Doetsch, V. | Deposit date: | 2014-10-27 | Release date: | 2015-10-28 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structural investigations of the p53/p73 homologs from the tunicate species Ciona intestinalis reveal the sequence requirements for the formation of a tetramerization domain. Protein Sci., 25, 2016
|
|
8POK
| Cryo-EM structure of cell-free synthesized human histamine H2 receptor coupled to heterotrimeric Gs protein in lipid environment | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, HISTAMINE, ... | Authors: | Schnelle, K, Koeck, Z, Persechino, M, Umbach, S, Schihada, H, Januliene, D, Parey, K, Pockes, S, Kolb, P, Doetsch, V, Moeller, A, Hilger, D, Bernhard, F. | Deposit date: | 2023-07-05 | Release date: | 2024-03-06 | Last modified: | 2024-10-09 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Cryo-EM structure of cell-free synthesized human histamine 2 receptor/G s complex in nanodisc environment. Nat Commun, 15, 2024
|
|
5OC7
| Crystal structure of the pleckstrin-homology domain of Bcr-Abl in complex with monobody Mb(Bcr-PH_4). | Descriptor: | Breakpoint cluster region protein,pleckstrin-homology domain of Bcr-Abl, D-MYO-INOSITOL-4,5-BISPHOSPHATE, GLYCEROL, ... | Authors: | Reckel, S, Reynaud, A, Pojer, F, Hantschel, O. | Deposit date: | 2017-06-29 | Release date: | 2017-12-27 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.652 Å) | Cite: | Structural and functional dissection of the DH and PH domains of oncogenic Bcr-Abl tyrosine kinase. Nat Commun, 8, 2017
|
|
3VTW
| Crystal structure of T7-tagged Optineurin LIR-fused human LC3B_2-119 | Descriptor: | Optineurin, microtubule-associated proteins 1A/1B light chain 3B, SULFATE ION | Authors: | Suzuki, H, Kawasaki, M, Kato, R, Wakatsuki, S. | Deposit date: | 2012-06-08 | Release date: | 2013-06-26 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.52 Å) | Cite: | Structural basis for phosphorylation-triggered autophagic clearance of Salmonella Biochem.J., 454, 2013
|
|
3VTV
| Crystal structure of Optineurin LIR-fused human LC3B_2-119 | Descriptor: | Optineurin, microtubule-associated proteins 1A/1B light chain 3B, SULFATE ION | Authors: | Suzuki, H, Kawasaki, M, Kato, R, Wakatsuki, S. | Deposit date: | 2012-06-08 | Release date: | 2013-06-26 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural basis for phosphorylation-triggered autophagic clearance of Salmonella Biochem.J., 454, 2013
|
|
7P7F
| Crystal structure of phosphorylated pT220 Casein Kinase I delta (CK1d), conformation 1 | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE, ADENOSINE MONOPHOSPHATE, ... | Authors: | Chaikuad, A, Zhubi, R, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2021-07-19 | Release date: | 2022-04-13 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Kinase domain autophosphorylation rewires the activity and substrate specificity of CK1 enzymes. Mol.Cell, 82, 2022
|
|
7P7G
| Crystal structure of phosphorylated pT220 Casein Kinase I delta (CK1d), conformation 2 and 3 | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, CITRIC ACID, ... | Authors: | Chaikuad, A, Zhubi, R, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2021-07-19 | Release date: | 2022-04-13 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Kinase domain autophosphorylation rewires the activity and substrate specificity of CK1 enzymes. Mol.Cell, 82, 2022
|
|
7P7H
| |
3VTU
| Crystal structure of human LC3B_2-119 | Descriptor: | Microtubule-associated proteins 1A/1B light chain 3B, SULFATE ION | Authors: | Suzuki, H, Kawasaki, M, Kato, R, Wakatsuki, S. | Deposit date: | 2012-06-08 | Release date: | 2013-06-26 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural basis for phosphorylation-triggered autophagic clearance of Salmonella Biochem.J., 454, 2013
|
|
5DPS
| |
5DPR
| |
5DPW
| |
6RYB
| |