7BXU
 
 | | CLC-7/Ostm1 membrane protein complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, H(+)/Cl(-) exchange transporter 7, Osteopetrosis-associated transmembrane protein 1 | | Authors: | Zhang, S.S, Yang, M.J. | | Deposit date: | 2020-04-20 | | Release date: | 2020-09-16 | | Last modified: | 2024-10-16 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Molecular insights into the human CLC-7/Ostm1 transporter.
Sci Adv, 6, 2020
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8TNI
 | | Cryo-EM structure of HIV-1 Env BG505 DS-SOSIP in complex with broadly neutralizing bi-specific antibody CAP256L-R27 targeting the CD4-binding site and the V2-apex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 BG505 DS-SOSIP gp120, ... | | Authors: | Zhou, T, Morano, N.C, Roark, R.S, Kwong, P.D, Xu, J. | | Deposit date: | 2023-08-01 | | Release date: | 2024-05-08 | | Last modified: | 2024-12-18 | | Method: | ELECTRON MICROSCOPY (3.61 Å) | | Cite: | Ultrapotent Broadly Neutralizing Human-llama Bispecific Antibodies against HIV-1.
Adv Sci, 11, 2024
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8TNH
 | | Cryo-EM structure of HIV-1 Env BG505 DS-SOSIP in complex with broadly neutralizing llama nanobody G36 targeting the CD4-binding site | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CD4-binding site nanobody G36, ... | | Authors: | Zhou, T, Kwong, P.D, Xu, J. | | Deposit date: | 2023-08-01 | | Release date: | 2024-05-08 | | Last modified: | 2024-12-18 | | Method: | ELECTRON MICROSCOPY (3.32 Å) | | Cite: | Ultrapotent Broadly Neutralizing Human-llama Bispecific Antibodies against HIV-1.
Adv Sci, 11, 2024
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8TNG
 | | Cryo-EM structure of HIV-1 Env BG505 DS-SOSIP in complex with broadly neutralizing llama nanobody R27 targeting the CD4-binding site | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CD4-binding site targeting nanobody R27, ... | | Authors: | Zhou, T, Kwong, P.D, Xu, J. | | Deposit date: | 2023-08-01 | | Release date: | 2024-05-08 | | Last modified: | 2024-12-18 | | Method: | ELECTRON MICROSCOPY (3.58 Å) | | Cite: | Ultrapotent Broadly Neutralizing Human-llama Bispecific Antibodies against HIV-1.
Adv Sci, 11, 2024
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8TE7
 | | Structure of TRNM-f.01 | | Descriptor: | TRNM-f.01 Fab Heavy Chain, TRNM-f.01 Fab Light Chain | | Authors: | Bender, M.F, Olia, A.S, Kwong, P.D. | | Deposit date: | 2023-07-05 | | Release date: | 2024-07-10 | | Last modified: | 2025-01-15 | | Method: | X-RAY DIFFRACTION (3.18 Å) | | Cite: | Potent and broad HIV-1 neutralization in fusion peptide-primed SHIV-infected macaques.
Cell, 187, 2024
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8TJS
 | | CRYO-EM STRUCTURE OF HIV-1 BG505DS-SOSIP.664 ENV TRIMER BOUND TO GPZ6-a.01 FAB | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody GPZ6-a.01 Heavy Chain, ... | | Authors: | Morano, N.C, Becker, J.E, Shapiro, L. | | Deposit date: | 2023-07-24 | | Release date: | 2024-07-31 | | Last modified: | 2025-01-15 | | Method: | ELECTRON MICROSCOPY (3.31 Å) | | Cite: | Potent and broad HIV-1 neutralization in fusion peptide-primed SHIV-infected macaques.
Cell, 187, 2024
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8TDX
 | | TRNM-b.01 in complex with HIV Env fusion peptide | | Descriptor: | Env Fusion Peptide, TRNM-b.01 Fab Heavy Chain, TRNM-b.01 Fab Light Chain | | Authors: | Olia, A.S, Kwong, P.D. | | Deposit date: | 2023-07-05 | | Release date: | 2024-07-10 | | Last modified: | 2025-01-15 | | Method: | X-RAY DIFFRACTION (2.09 Å) | | Cite: | Potent and broad HIV-1 neutralization in fusion peptide-primed SHIV-infected macaques.
Cell, 187, 2024
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8TNU
 | | Cryo-EM structure of TRNM-b*01 Fab in complex with HIV-1 Env trimer BG505.DS SOSIP | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 DS-SOSIP Surface protein gp120, ... | | Authors: | Roark, R.S, Morano, N.C, Shapiro, L.S, Kwong, P.D. | | Deposit date: | 2023-08-02 | | Release date: | 2024-08-07 | | Last modified: | 2025-01-15 | | Method: | ELECTRON MICROSCOPY (3.36 Å) | | Cite: | Potent and broad HIV-1 neutralization in fusion peptide-primed SHIV-infected macaques.
Cell, 187, 2024
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8TOP
 | | Cryo-EM structure of HIV-1 Env BG505 DS-SOSIP in complex with antibody GPZ6-b.01 targeting the fusion peptide | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 BG505 DS-SOSIP glycoprotein gp41, ... | | Authors: | Zhou, T, Morano, N.C, Roark, R.S, Kwong, P.D. | | Deposit date: | 2023-08-03 | | Release date: | 2024-08-07 | | Last modified: | 2025-01-15 | | Method: | ELECTRON MICROSCOPY (3.52 Å) | | Cite: | Potent and broad HIV-1 neutralization in fusion peptide-primed SHIV-infected macaques.
Cell, 187, 2024
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8TO9
 | | Cryo-EM structure of TRNM-f*01 Fab in complex with HIV-1 Env trimer ConC SOSIP | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ... | | Authors: | Roark, R.S, Morano, N.C, Shapiro, L.S, Kwong, P.D. | | Deposit date: | 2023-08-03 | | Release date: | 2024-08-07 | | Last modified: | 2025-05-14 | | Method: | ELECTRON MICROSCOPY (4.03 Å) | | Cite: | Potent and broad HIV-1 neutralization in fusion peptide-primed SHIV-infected macaques.
Cell, 187, 2024
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8TOX
 | | Cryo-EM structure of BG505 Env mutant A517E in complex with antibody ACS202 Fab | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ... | | Authors: | Wang, S, Kwong, P.D. | | Deposit date: | 2023-08-04 | | Release date: | 2024-08-14 | | Last modified: | 2025-02-26 | | Method: | ELECTRON MICROSCOPY (2.3 Å) | | Cite: | Vaccine-elicited and naturally elicited antibodies differ in their recognition of the HIV-1 fusion peptide.
Front Immunol, 15, 2024
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8TL2
 | | CRYO-EM STRUCTURE OF HIV-1 BG505DS-SOSIP.664 ENV TRIMER BOUND TO DJ85-c.01 FAB | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 DS-SOSIP Surface protein gp120, ... | | Authors: | Pletnev, S, Hoyt, F, Fischer, E, Kwong, P. | | Deposit date: | 2023-07-26 | | Release date: | 2024-08-28 | | Last modified: | 2025-01-15 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Potent and broad HIV-1 neutralization in fusion peptide-primed SHIV-infected macaques.
Cell, 187, 2024
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8TL3
 | | CRYO-EM STRUCTURE OF HIV-1 BG505DS-SOSIP.664 ENV TRIMER BOUND TO DJ85-d.01 FAB | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 DS-SOSIP glycoprotein gp120, ... | | Authors: | Pletnev, S, Hoyt, F, Fischer, E, Kwong, P. | | Deposit date: | 2023-07-26 | | Release date: | 2024-08-28 | | Last modified: | 2025-01-15 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Potent and broad HIV-1 neutralization in fusion peptide-primed SHIV-infected macaques.
Cell, 187, 2024
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8TL5
 | | CRYO-EM STRUCTURE OF HIV-1 BG505DS-SOSIP.664 ENV TRIMER BOUND TO HERH-c.01 FAB | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 DS-SOSIP Surface protein gp120, ... | | Authors: | Pletnev, S, Hoyt, F, Fischer, E, Kwong, P. | | Deposit date: | 2023-07-26 | | Release date: | 2024-08-28 | | Last modified: | 2025-01-15 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Potent and broad HIV-1 neutralization in fusion peptide-primed SHIV-infected macaques.
Cell, 187, 2024
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8TKC
 | | CRYO-EM STRUCTURE OF HIV-1 BG505DS-SOSIP.664 ENV TRIMER BOUND TO DJ85-b.01 FAB | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 DS-SOSIP Surface protein gp120, ... | | Authors: | Pletnev, S, Hoyt, F, Fischer, E, Kwong, P. | | Deposit date: | 2023-07-25 | | Release date: | 2024-08-28 | | Last modified: | 2025-01-15 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Potent and broad HIV-1 neutralization in fusion peptide-primed SHIV-infected macaques.
Cell, 187, 2024
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8TL4
 | | CRYO-EM STRUCTURE OF HIV-1 BG505DS-SOSIP.664 ENV TRIMER BOUND TO DJ85-e.01 FAB | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 DS-SOSIP Surface protein gp120, ... | | Authors: | Pletnev, S, Hoyt, F, Fischer, E, Kwong, P. | | Deposit date: | 2023-07-26 | | Release date: | 2024-08-28 | | Last modified: | 2025-01-15 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Potent and broad HIV-1 neutralization in fusion peptide-primed SHIV-infected macaques.
Cell, 187, 2024
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9D3D
 | | Cryo-EM structure of PGT145 R100aS Fab bound to HIV-1 BG505 DS-SOSIP.664 Env trimer | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 DS-SOSIP glycoprotein gp41, ... | | Authors: | Hodges, S, Morano, N.C, Shapiro, L, Kwong, P.D, Gorman, J. | | Deposit date: | 2024-08-09 | | Release date: | 2024-12-25 | | Last modified: | 2025-02-05 | | Method: | ELECTRON MICROSCOPY (3.41 Å) | | Cite: | Structural development of the HIV-1 apex-directed PGT145-PGDM1400 antibody lineage.
Cell Rep, 44, 2025
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9D1W
 | | Cryo-EM structure of PGDM1400 Fab bound to HIV-1 BG505 DS-SOSIP.664 Env trimer | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 BG505 DS-SOSIP glycoprotein gp41, ... | | Authors: | Kanai, T, Morano, N.C, Shapiro, L, Kwong, P.D, Gorman, J. | | Deposit date: | 2024-08-08 | | Release date: | 2024-12-25 | | Last modified: | 2025-02-05 | | Method: | ELECTRON MICROSCOPY (3.44 Å) | | Cite: | Structural development of the HIV-1 apex-directed PGT145-PGDM1400 antibody lineage.
Cell Rep, 44, 2025
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8ZCE
 | | Cryo-EM structure of GPR4 complexed with Gs in pH6.0 | | Descriptor: | G-protein coupled receptor 4, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | Authors: | Yue, X.L, Wu, L.J, Hua, T, Liu, Z.J. | | Deposit date: | 2024-04-29 | | Release date: | 2025-04-23 | | Last modified: | 2025-06-18 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Structural basis of stepwise proton sensing-mediated GPCR activation.
Cell Res., 35, 2025
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8ZCF
 | | Cryo-EM structure of GPR4 complexed with Gs in pH7.5 | | Descriptor: | G-protein coupled receptor 4, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | Authors: | Yue, X.L, Wu, L.J, Hua, T, Liu, Z.J. | | Deposit date: | 2024-04-29 | | Release date: | 2025-04-23 | | Last modified: | 2025-06-25 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Structural basis of stepwise proton sensing-mediated GPCR activation.
Cell Res., 35, 2025
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7CPO
 | | Crystal Structure of Anolis carolinensis MHC I complex | | Descriptor: | HIS-VAL-TYR-GLY-PRO-LEU-LYS-PRO-ILE, MHC CLASS I ANTIGEN, beta2-microglobulin | | Authors: | Wang, Y, Qu, Z, Ma, L, Wei, X, Zhang, N, Xia, C. | | Deposit date: | 2020-08-07 | | Release date: | 2021-01-27 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | The Crystal Structure of the MHC Class I (MHC-I) Molecule in the Green Anole Lizard Demonstrates the Unique MHC-I System in Reptiles.
J Immunol., 206, 2021
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6MTS
 | | Crystal structure of VRC43.03 Fab | | Descriptor: | Antibody VRC43.03 Fab heavy chain, Antibody VRC43.03 Fab light chain | | Authors: | Kwon, Y.D, Druz, A, Law, W.H, Peng, D, Doria-Rose, N.A, Kwong, P.D. | | Deposit date: | 2018-10-21 | | Release date: | 2019-03-27 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (2.437 Å) | | Cite: | Longitudinal Analysis Reveals Early Development of Three MPER-Directed Neutralizing Antibody Lineages from an HIV-1-Infected Individual.
Immunity, 50, 2019
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6MTT
 | | Crystal structure of VRC46.01 Fab in complex with gp41 peptide | | Descriptor: | Antibody VRC46.01 Fab heavy chain, Antibody VRC46.01 Fb light chain, RV217 founder virus gp41 peptide | | Authors: | Kwon, Y.D, Druz, A, Law, W.H, Peng, D, Veradi, R, Doria-Rose, N.A, Kwong, P.D. | | Deposit date: | 2018-10-21 | | Release date: | 2019-03-27 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Longitudinal Analysis Reveals Early Development of Three MPER-Directed Neutralizing Antibody Lineages from an HIV-1-Infected Individual.
Immunity, 50, 2019
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7CY2
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7CZ2
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