8W3R
 
 | | Crystal structure of prefusion-stabilized RSV F protein UFCR2-iSS-P2-NQ in complex with A4 single-chain fragment variable | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, A4 single-chain fragment variable, prefusion-stabilized RSV F protein UFCR2-iSS-P2-NQ | | Authors: | Lee, Y.Z, Stanfield, R.L, Wilson, I.A, Zhu, J. | | Deposit date: | 2024-02-22 | | Release date: | 2025-01-15 | | Method: | X-RAY DIFFRACTION (4.02 Å) | | Cite: | Rational design of uncleaved prefusion-closed trimer vaccines for human respiratory syncytial virus and metapneumovirus.
Nat Commun, 15, 2024
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8W3F
 | | Crystal structure of prefusion-stabilized RSV F protein UFCR1-P2-NQ | | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Prefusion-stabilized RSV F protein UFCR1-P2-NQ | | Authors: | Lee, Y.Z, Stanfield, R.L, Wilson, I.A, Zhu, J. | | Deposit date: | 2024-02-22 | | Release date: | 2025-01-15 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Rational design of uncleaved prefusion-closed trimer vaccines for human respiratory syncytial virus and metapneumovirus.
Nat Commun, 15, 2024
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8W3Q
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8W3O
 | | Crystal structure of prefusion-stabilized RSV F protein UFCR3-GDQ | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, prefusion-stabilized RSV F protein UFCR3-GDQ | | Authors: | Lee, Y.Z, Stanfield, R.L, Wilson, I.A, Zhu, J. | | Deposit date: | 2024-02-22 | | Release date: | 2025-01-15 | | Method: | X-RAY DIFFRACTION (2.31 Å) | | Cite: | Rational design of uncleaved prefusion-closed trimer vaccines for human respiratory syncytial virus and metapneumovirus.
Nat Commun, 15, 2024
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8W3E
 | | Crystal structure of prefusion-stabilized RSV F protein UFCR1 | | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Lee, Y.Z, Stanfield, R.L, Wilson, I.A, Zhu, J. | | Deposit date: | 2024-02-22 | | Release date: | 2025-01-15 | | Method: | X-RAY DIFFRACTION (2.26 Å) | | Cite: | Rational design of uncleaved prefusion-closed trimer vaccines for human respiratory syncytial virus and metapneumovirus.
Nat Commun, 15, 2024
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8W3G
 | | Crystal structure of prefusion-stabilized RSV F protein UFCR1(1TD0) | | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Prefusion-stabilized RSV F protein UFCR1(1TD0) | | Authors: | Lee, Y.Z, Stanfield, R.L, Wilson, I.A, Zhu, J. | | Deposit date: | 2024-02-22 | | Release date: | 2025-01-15 | | Method: | X-RAY DIFFRACTION (2.28 Å) | | Cite: | Rational design of uncleaved prefusion-closed trimer vaccines for human respiratory syncytial virus and metapneumovirus.
Nat Commun, 15, 2024
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8W3H
 | | Crystal structure of prefusion-stabilized RSV F protein UFCR1-iSS | | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Prefusion-stabilized RSV F protein UFCR1-iSS | | Authors: | Lee, Y.Z, Stanfield, R.L, Wilson, I.A, Zhu, J. | | Deposit date: | 2024-02-22 | | Release date: | 2025-01-15 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Rational design of uncleaved prefusion-closed trimer vaccines for human respiratory syncytial virus and metapneumovirus.
Nat Commun, 15, 2024
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8W3K
 | | Crystal structure of prefusion-stabilized RSV F protein UFCR2-iSS-NQ | | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Prefusion-stabilized RSV F protein UFCR2-iSS-NQ | | Authors: | Lee, Y.Z, Stanfield, R.L, Wilson, I.A, Zhu, J. | | Deposit date: | 2024-02-22 | | Release date: | 2025-01-15 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Rational design of uncleaved prefusion-closed trimer vaccines for human respiratory syncytial virus and metapneumovirus.
Nat Commun, 15, 2024
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8W3I
 | | Crystal structure of prefusion-stabilized RSV F protein UFCR1-L2 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, Prefusion-stabilized RSV F protein UFCR1-L2 | | Authors: | Lee, Y.Z, Stanfield, R.L, Wilson, I.A, Zhu, J. | | Deposit date: | 2024-02-22 | | Release date: | 2025-01-15 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Rational design of uncleaved prefusion-closed trimer vaccines for human respiratory syncytial virus and metapneumovirus.
Nat Commun, 15, 2024
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8W3L
 | | Crystal structure of prefusion-stabilized RSV F protein UFCR2-iSS-P2-NQ | | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, prefusion-stabilized RSV F protein UFCR2-iSS-P2-NQ | | Authors: | Lee, Y.Z, Stanfield, R.L, Wilson, I.A, Zhu, J. | | Deposit date: | 2024-02-22 | | Release date: | 2025-01-15 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Rational design of uncleaved prefusion-closed trimer vaccines for human respiratory syncytial virus and metapneumovirus.
Nat Commun, 15, 2024
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8W3N
 | | Crystal structure of prefusion-stabilized RSV F protein UFCR3 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, prefusion-stabilized RSV F protein UFCR3 | | Authors: | Lee, Y.Z, Stanfield, R.L, Wilson, I.A, Zhu, J. | | Deposit date: | 2024-02-22 | | Release date: | 2025-01-15 | | Method: | X-RAY DIFFRACTION (2.69 Å) | | Cite: | Rational design of uncleaved prefusion-closed trimer vaccines for human respiratory syncytial virus and metapneumovirus.
Nat Commun, 15, 2024
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8W3P
 | | Crystal structure of prefusion-stabilized RSV F protein UFCR3-D(1TD0) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, prefusion-stabilized RSV F protein UFCR3-D(1TD0) | | Authors: | Lee, Y.Z, Stanfield, R.L, Wilson, I.A, Zhu, J. | | Deposit date: | 2024-02-22 | | Release date: | 2025-01-15 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Rational design of uncleaved prefusion-closed trimer vaccines for human respiratory syncytial virus and metapneumovirus.
Nat Commun, 15, 2024
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1RUM
 | | Crystal structure (F) of H2O2-soaked cationic cyclization antibody 4C6 fab at pH 8.5 with a data set collected at SSRL beamline 9-1. | | Descriptor: | BENZOIC ACID, GLYCEROL, immunoglobulin igg2a, ... | | Authors: | Zhu, X, Wentworth Jr, P, Wentworth, A.D, Eschenmoser, A, Lerner, R.A, Wilson, I.A. | | Deposit date: | 2003-12-11 | | Release date: | 2004-03-02 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (1.48 Å) | | Cite: | Probing the antibody-catalyzed water-oxidation pathway at atomic resolution.
Proc.Natl.Acad.Sci.USA, 110, 2004
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1RUA
 | | Crystal structure (B) of u.v.-irradiated cationic cyclization antibody 4C6 fab at pH 4.6 with a data set collected at SSRL beamline 11-1. | | Descriptor: | ACETATE ION, BENZOIC ACID, GLYCEROL, ... | | Authors: | Zhu, X, Wentworth Jr, P, Wentworth, A.D, Eschenmoser, A, Lerner, R.A, Wilson, I.A. | | Deposit date: | 2003-12-11 | | Release date: | 2004-03-02 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Probing the antibody-catalyzed water-oxidation pathway at atomic resolution.
Proc.Natl.Acad.Sci.USA, 110, 2004
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1RUP
 | | Crystal structure (G) of native cationic cyclization antibody 4C6 fab at pH 8.5 with a data set collected at APS beamline 19-ID | | Descriptor: | BENZOIC ACID, GLYCEROL, immunoglobulin igg2a, ... | | Authors: | Zhu, X, Wentworth Jr, P, Wentworth, A.D, Eschenmoser, A, Lerner, R.A, Wilson, I.A. | | Deposit date: | 2003-12-11 | | Release date: | 2004-03-02 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Probing the antibody-catalyzed water-oxidation pathway at atomic resolution.
Proc.Natl.Acad.Sci.USA, 110, 2004
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1RU9
 | | Crystal Structure (A) of u.v.-irradiated cationic cyclization antibody 4C6 Fab at pH 4.6 with a data set collected in-house. | | Descriptor: | ACETATE ION, BENZOIC ACID, GLYCEROL, ... | | Authors: | Zhu, X, Wentworth Jr, P, Wentworth, A.D, Eschenmoser, A, Lerner, R.A, Wilson, I.A. | | Deposit date: | 2003-12-11 | | Release date: | 2004-03-02 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Probing the antibody-catalyzed water-oxidation pathway at atomic resolution.
Proc.Natl.Acad.Sci.USA, 110, 2004
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1RUK
 | | Crystal structure (C) of native cationic cyclization antibody 4C6 fab at pH 4.6 with a data set collected at SSRL beamline 9-1 | | Descriptor: | ACETATE ION, BENZOIC ACID, GLYCEROL, ... | | Authors: | Zhu, X, Wentworth Jr, P, Wentworth, A.D, Eschenmoser, A, Lerner, R.A, Wilson, I.A. | | Deposit date: | 2003-12-11 | | Release date: | 2004-03-02 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Probing the antibody-catalyzed water-oxidation pathway at atomic resolution.
Proc.Natl.Acad.Sci.USA, 110, 2004
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1RUL
 | | Crystal Structure (D) of u.v.-irradiated cationic cyclization antibody 4C6 Fab at pH 5.6 with a data set collected at SSRL beamline 11-1. | | Descriptor: | ACETATE ION, BENZOIC ACID, GLYCEROL, ... | | Authors: | Zhu, X, Wentworth Jr, P, Wentworth, A.D, Eschenmoser, A, Lerner, R.A, Wilson, I.A. | | Deposit date: | 2003-12-11 | | Release date: | 2004-03-02 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.88 Å) | | Cite: | Probing the antibody-catalyzed water-oxidation pathway at atomic resolution.
Proc.Natl.Acad.Sci.USA, 110, 2004
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1RUR
 | | Crystal Structure (I) of native Diels-Alder antibody 13G5 Fab at pH 8.0 with a data set collected at SSRL beamline 9-1. | | Descriptor: | ZINC ION, immunoglobulin 13G5, heavy chain, ... | | Authors: | Zhu, X, Wentworth Jr, P, Wentworth, A.D, Eschenmoser, A, Lerner, R.A, Wilson, I.A. | | Deposit date: | 2003-12-11 | | Release date: | 2004-03-02 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Probing the antibody-catalyzed water-oxidation pathway at atomic resolution.
Proc.Natl.Acad.Sci.USA, 110, 2004
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1RUQ
 | | Crystal Structure (H) of u.v.-irradiated Diels-Alder antibody 13G5 Fab at pH 8.0 with a data set collected in house. | | Descriptor: | ZINC ION, immunoglobulin 13G5 heavy chain, immunoglobulin 13G5 light chain | | Authors: | Zhu, X, Wentworth Jr, P, Wentworth, A.D, Eschenmoser, A, Lerner, R.A, Wilson, I.A. | | Deposit date: | 2003-12-11 | | Release date: | 2004-03-02 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (1.86 Å) | | Cite: | Probing the antibody-catalyzed water-oxidation pathway at atomic resolution.
Proc.Natl.Acad.Sci.USA, 110, 2004
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4QDH
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4QGT
 | | The Crystal Structure of Human IgG Fc Domain with Enhanced Aromatic Sequon | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... | | Authors: | Kong, L, Connelly, S.C, Wilson, I.A. | | Deposit date: | 2014-05-25 | | Release date: | 2015-04-08 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (2.99 Å) | | Cite: | Stabilizing the CH2 Domain of an Antibody by Engineering in an Enhanced Aromatic Sequon.
Acs Chem.Biol., 11, 2016
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4R26
 | | Crystal structure of human Fab PGT124, a broadly neutralizing and potent HIV-1 neutralizing antibody | | Descriptor: | GLYCEROL, PGR124-Light Chain, PGT124-Heavy Chain | | Authors: | Garces, F, Kong, L, Wilson, I.A. | | Deposit date: | 2014-08-08 | | Release date: | 2014-10-08 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (2.4969 Å) | | Cite: | Structural Evolution of Glycan Recognition by a Family of Potent HIV Antibodies.
Cell(Cambridge,Mass.), 159, 2014
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4R2G
 | | Crystal Structure of PGT124 Fab bound to HIV-1 JRCSF gp120 core and to CD4 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | | Authors: | Garces, F, Wilson, I.A. | | Deposit date: | 2014-08-11 | | Release date: | 2014-10-08 | | Last modified: | 2024-12-25 | | Method: | X-RAY DIFFRACTION (3.283 Å) | | Cite: | Structural Evolution of Glycan Recognition by a Family of Potent HIV Antibodies.
Cell(Cambridge,Mass.), 159, 2014
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1A3L
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