6WUR
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4Q1Q
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3HW5
| crystal structure of avian influenza virus PA_N in complex with AMP | Descriptor: | ADENOSINE MONOPHOSPHATE, MAGNESIUM ION, Polymerase acidic protein | Authors: | Zhao, C, Lou, Z, Guo, Y, Ma, M, Chen, Y, Liang, S, Rao, Z. | Deposit date: | 2009-06-17 | Release date: | 2009-10-13 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.81 Å) | Cite: | Nucleoside monophosphate complex structures of the endonuclease domain from the influenza virus polymerase PA subunit reveal the substrate binding site inside the catalytic center J.Virol., 83, 2009
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6WUS
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5IXJ
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2B1B
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3HW4
| Crystal structure of avian influenza A virus in complex with TMP | Descriptor: | MAGNESIUM ION, Polymerase acidic protein, THYMIDINE-5'-PHOSPHATE | Authors: | Zhao, C, Lou, Z, Guo, Y, Ma, M, Chen, Y, Rao, Z. | Deposit date: | 2009-06-17 | Release date: | 2009-11-10 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Nucleoside monophosphate complex structures of the endonuclease domain from the influenza virus polymerase PA subunit reveal the substrate binding site inside the catalytic center J.Virol., 83, 2009
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6E1C
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2B1C
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3HW6
| Crystal structure of avian influenza virus PA_N in complex with Mn | Descriptor: | MANGANESE (II) ION, Polymerase acidic protein | Authors: | Zhao, C, Lou, Z, Guo, Y, Ma, M, Chen, Y, Rao, Z. | Deposit date: | 2009-06-17 | Release date: | 2009-10-13 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Nucleoside monophosphate complex structures of the endonuclease domain from the influenza virus polymerase PA subunit reveal the substrate binding site inside the catalytic center J.Virol., 83, 2009
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3HW3
| The crystal structure of avian influenza virus PA_N in complex with UMP | Descriptor: | MAGNESIUM ION, Polymerase acidic protein, URIDINE-5'-MONOPHOSPHATE | Authors: | Zhao, C, Lou, Z, Guo, Y, Ma, M, Chen, Y, Rao, Z. | Deposit date: | 2009-06-17 | Release date: | 2009-10-13 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Nucleoside monophosphate complex structures of the endonuclease domain from the influenza virus polymerase PA subunit reveal the substrate binding site inside the catalytic center J.Virol., 83, 2009
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2B1D
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7MWH
| Crystal structure of BAZ2A with DNA | Descriptor: | Bromodomain adjacent to zinc finger domain protein 2A, DNA (5'-D(*CP*GP*GP*AP*AP*TP*GP*TP*AP*GP*GP*C)-3'), DNA (5'-D(*GP*CP*CP*TP*AP*(5CM)P*AP*TP*TP*CP*CP*G)-3'), ... | Authors: | Liu, K, Dong, A, Li, Y, Loppnau, P, Edwards, A.M, Arrowsmith, C.H, Min, J, Structural Genomics Consortium (SGC) | Deposit date: | 2021-05-17 | Release date: | 2022-08-31 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Crystal structure of the BAZ2B TAM domain. Heliyon, 8, 2022
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4KJU
| Crystal structure of XIAP-Bir2 with a bound benzodiazepinone inhibitor. | Descriptor: | E3 ubiquitin-protein ligase XIAP, N-{(3S)-5-(4-aminobenzoyl)-1-[(2-methoxynaphthalen-1-yl)methyl]-2-oxo-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-3-yl}-N~2~-methyl-L-alaninamide, ZINC ION | Authors: | Lukacs, C.M, Janson, C.A. | Deposit date: | 2013-05-03 | Release date: | 2013-11-27 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Optimization of Benzodiazepinones as Selective Inhibitors of the X-Linked Inhibitor of Apoptosis Protein (XIAP) Second Baculovirus IAP Repeat (BIR2) Domain. J.Med.Chem., 56, 2013
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4KJV
| Crystal structure of XIAP-Bir2 with a bound spirocyclic benzoxazepinone inhibitor. | Descriptor: | 6-methoxy-5-({(3S)-3-[(N-methyl-L-alanyl)amino]-4-oxo-2',3,3',4,5',6'-hexahydro-5H-spiro[1,5-benzoxazepine-2,4'-pyran]-5-yl}methyl)naphthalene-2-carboxylic acid, E3 ubiquitin-protein ligase XIAP, ZINC ION | Authors: | Lukacs, C.M, Janson, C.A. | Deposit date: | 2013-05-03 | Release date: | 2013-11-27 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Optimization of Benzodiazepinones as Selective Inhibitors of the X-Linked Inhibitor of Apoptosis Protein (XIAP) Second Baculovirus IAP Repeat (BIR2) Domain. J.Med.Chem., 56, 2013
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2NAE
| Membrane-bound mouse CD28 cytoplasmic tail | Descriptor: | T-cell-specific surface glycoprotein CD28 | Authors: | Li, H, Xu, C, Pan, W. | Deposit date: | 2015-12-23 | Release date: | 2016-12-21 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Dynamic regulation of CD28 conformation and signaling by charged lipids and ions. Nat.Struct.Mol.Biol., 24, 2017
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2MP0
| Protein Phosphorylation upon a Fleeting Encounter | Descriptor: | Glucose-specific phosphotransferase enzyme IIA component, PHOSPHITE ION, Phosphoenolpyruvate-protein phosphotransferase | Authors: | Xing, Q, Yang, J, Huang, P, Zhang, W, Tang, C. | Deposit date: | 2014-05-08 | Release date: | 2014-08-20 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Visualizing an ultra-weak protein-protein interaction in phosphorylation signaling. Angew.Chem.Int.Ed.Engl., 53, 2014
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1GG5
| CRYSTAL STRUCTURE OF A COMPLEX OF HUMAN NAD[P]H-QUINONE OXIDOREDUCTASE AND A CHEMOTHERAPEUTIC DRUG (E09) AT 2.5 A RESOLUTION | Descriptor: | 3-HYDROXYMETHYL-5-AZIRIDINYL-1METHYL-2-[1H-INDOLE-4,7-DIONE]-PROPANOL, FLAVIN-ADENINE DINUCLEOTIDE, NAD(P)H DEHYDROGENASE [QUINONE] 1 | Authors: | Faig, M, Bianchet, M.A, Winski, S, Hargreaves, R, Moody, C.J, Hudnott, A.R, Ross, D, Amzel, L.M. | Deposit date: | 2000-07-12 | Release date: | 2001-09-12 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure-based development of anticancer drugs: complexes of NAD(P)H:quinone oxidoreductase 1 with chemotherapeutic quinones. Structure, 9, 2001
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1H66
| CRYSTAL STRUCTURE OF HUMAN NAD[P]H-QUINONE OXIDOREDUCTASE CO WITH 2,5-diaziridinyl-3-hydroxyl-6-methyl-1,4-benzoquinone | Descriptor: | 2,5-DIAZIRIDIN-1-YL-3-(HYDROXYMETHYL)-6-METHYLCYCLOHEXA-2,5-DIENE-1,4-DIONE, FLAVIN-ADENINE DINUCLEOTIDE, NAD(P)H DEHYDROGENASE [QUINONE] 1 | Authors: | Faig, M, Bianchet, M.A, Winski, S, Ross, D, Amzel, L.M. | Deposit date: | 2001-06-06 | Release date: | 2001-09-05 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure-Based Development of Anticancer Drugs: Complexes of Nad(P)H:Quinone Oxidoreductase 1 with Chemotherapeutic Quinones Structure, 9, 2001
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7QXX
| Proteasome-ZFAND5 Complex Z+E state | Descriptor: | 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, 26S protease regulatory subunit 7, ... | Authors: | Zhu, Y, Lu, Y. | Deposit date: | 2022-01-27 | Release date: | 2023-02-08 | Last modified: | 2024-09-04 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | Molecular mechanism for activation of the 26S proteasome by ZFAND5. Mol.Cell, 83, 2023
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7QXN
| Proteasome-ZFAND5 Complex Z+A state | Descriptor: | 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... | Authors: | Zhu, Y, Lu, Y. | Deposit date: | 2022-01-26 | Release date: | 2023-02-08 | Last modified: | 2024-09-04 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Molecular mechanism for activation of the 26S proteasome by ZFAND5. Mol.Cell, 83, 2023
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7QY7
| Proteasome-ZFAND5 Complex Z-A state | Descriptor: | 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... | Authors: | Zhu, Y, Lu, Y. | Deposit date: | 2022-01-27 | Release date: | 2023-02-08 | Last modified: | 2024-09-04 | Method: | ELECTRON MICROSCOPY (4.7 Å) | Cite: | Molecular mechanism for activation of the 26S proteasome by ZFAND5. Mol.Cell, 83, 2023
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7QYB
| Proteasome-ZFAND5 Complex Z-C state | Descriptor: | 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... | Authors: | Zhu, Y, Lu, Y. | Deposit date: | 2022-01-27 | Release date: | 2023-02-08 | Last modified: | 2024-09-04 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Molecular mechanism for activation of the 26S proteasome by ZFAND5. Mol.Cell, 83, 2023
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7QXP
| Proteasome-ZFAND5 Complex Z+B state | Descriptor: | 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... | Authors: | Zhu, Y, Lu, Y. | Deposit date: | 2022-01-26 | Release date: | 2023-02-08 | Last modified: | 2024-09-04 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Molecular mechanism for activation of the 26S proteasome by ZFAND5. Mol.Cell, 83, 2023
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7QXU
| Proteasome-ZFAND5 Complex Z+C state | Descriptor: | 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, 26S protease regulatory subunit 7, ... | Authors: | Zhu, Y, Lu, Y. | Deposit date: | 2022-01-27 | Release date: | 2023-02-08 | Last modified: | 2024-09-04 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Molecular mechanism for activation of the 26S proteasome by ZFAND5. Mol.Cell, 83, 2023
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