2JOK
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![BU of 2jok by Molmil](/molmil-images/mine/2jok) | NMR structure of the catalytic domain of guanine nucleotide exchange factor BopE from Burkholderia pseudomallei | Descriptor: | Putative G-nucleotide exchange factor | Authors: | Wu, H, Upadhyay, A, Williams, C, Galyov, E.E, van den Elsen, J.M.H, Bagby, S. | Deposit date: | 2007-03-14 | Release date: | 2007-09-18 | Last modified: | 2023-12-20 | Method: | SOLUTION NMR | Cite: | The guanine-nucleotide-exchange factor BopE from Burkholderia pseudomallei adopts a compact version of the Salmonella SopE/SopE2 fold and undergoes a closed-to-open conformational change upon interaction with Cdc42 Biochem.J., 411, 2008
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2JVG
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![BU of 2jvg by Molmil](/molmil-images/mine/2jvg) | Structure of C3-binding domain 4 of Staphylococcus aureus protein Sbi | Descriptor: | IgG-binding protein SBI | Authors: | Upadhyay, A, Burman, J, Clark, E.A, van den Elsen, J.M.H, Bagby, S. | Deposit date: | 2007-09-20 | Release date: | 2008-06-10 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structure-function analysis of the C3 binding region of Staphylococcus aureus immune subversion protein Sbi. J.Biol.Chem., 283, 2008
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2JVH
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![BU of 2jvh by Molmil](/molmil-images/mine/2jvh) | Structure of C3-binding domain 4 of S. aureus protein Sbi | Descriptor: | IgG-binding protein SBI | Authors: | Upadhyay, A, Burman, J, Clark, E.A, van den Elsen, J.M.H, Bagby, S. | Deposit date: | 2007-09-20 | Release date: | 2008-06-10 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structure-function analysis of the C3 binding region of Staphylococcus aureus immune subversion protein Sbi. J.Biol.Chem., 283, 2008
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4JCJ
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![BU of 4jcj by Molmil](/molmil-images/mine/4jcj) | Crystal structure of Isl1 LIM domains with Ldb1 LIM-interaction domain | Descriptor: | Insulin gene enhancer protein ISL-1,LIM domain-binding protein 1, ZINC ION | Authors: | Gadd, M.S, Jacques, D.A, Guss, J.M, Matthews, J.M. | Deposit date: | 2013-02-21 | Release date: | 2013-06-19 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | A structural basis for the regulation of the LIM-homeodomain protein islet 1 (Isl1) by intra- and intermolecular interactions. J.Biol.Chem., 288, 2013
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6PCY
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![BU of 6pcy by Molmil](/molmil-images/mine/6pcy) | |
2BF3
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![BU of 2bf3 by Molmil](/molmil-images/mine/2bf3) | Crystal structure of a toluene 4-monooxygenase catalytic effector protein variant missing ten N-terminal residues (delta-N10 T4moD) | Descriptor: | HEPTANE-1,2,3-TRIOL, TOLUENE-4-MONOOXYGENASE SYSTEM PROTEIN D | Authors: | Lountos, G.T, Mitchell, K.H, Studts, J.M, Fox, B.G, Orville, A.M. | Deposit date: | 2004-12-03 | Release date: | 2005-05-19 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Crystal Structures and Functional Studies of T4Mod, the Toluene 4-Monooxygenase Catalytic Effector Protein Biochemistry, 44, 2005
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2BF5
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![BU of 2bf5 by Molmil](/molmil-images/mine/2bf5) | Crystal structure of a toluene 4-monooxygenase catalytic effector protein variant missing four N-terminal residues (delta-N4 T4moD) | Descriptor: | TOLUENE-4-MONOOXYGENASE SYSTEM PROTEIN D | Authors: | Lountos, G.T, Mitchell, K.H, Studts, J.M, Fox, B.G, Orville, A.M. | Deposit date: | 2004-12-03 | Release date: | 2005-05-19 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.71 Å) | Cite: | Crystal Structures and Functional Studies of T4Mod, the Toluene 4-Monooxygenase Catalytic Effector Protein Biochemistry, 44, 2005
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2BF2
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![BU of 2bf2 by Molmil](/molmil-images/mine/2bf2) | Crystal structure of native toluene-4-monooxygenase catalytic effector protein, T4moD | Descriptor: | TOLUENE-4-MONOOXYGENASE SYSTEM PROTEIN D | Authors: | Lountos, G.T, Mitchell, K.H, Studts, J.M, Fox, B.G, Orville, A.M. | Deposit date: | 2004-12-03 | Release date: | 2005-05-19 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal Structures and Functional Studies of T4Mod, the Toluene 4-Monooxygenase Catalytic Effector Protein Biochemistry, 44, 2005
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6PTL
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4YHF
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![BU of 4yhf by Molmil](/molmil-images/mine/4yhf) | Bruton's tyrosine kinase in complex with a t-butyl cyanoacrylamide inhibitor | Descriptor: | (2S)-2-({(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl}carbonyl)-4,4-dimethylpentanenitrile, 1,2-ETHANEDIOL, CHLORIDE ION, ... | Authors: | Paavilainen, V.O, McFarland, J.M, Taunton, J. | Deposit date: | 2015-02-27 | Release date: | 2015-05-13 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Prolonged and tunable residence time using reversible covalent kinase inhibitors. Nat.Chem.Biol., 11, 2015
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4YNQ
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![BU of 4ynq by Molmil](/molmil-images/mine/4ynq) | TREX1-dsDNA complex | Descriptor: | DNA (24-MER), DNA (5'-D(P*GP*TP*GP*CP*TP*GP*AP*CP*GP*TP*CP*AP*GP*CP*AP*CP*GP*AP*CP*G)-3'), MAGNESIUM ION, ... | Authors: | Fye, J.M, Harvey, S, Perrino, F.W, Hollis, T. | Deposit date: | 2015-03-10 | Release date: | 2015-05-27 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Exonuclease TREX1 degrades double-stranded DNA to prevent spontaneous lupus-like inflammatory disease. Proc.Natl.Acad.Sci.USA, 112, 2015
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1CE5
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![BU of 1ce5 by Molmil](/molmil-images/mine/1ce5) | BOVINE PANCREAS BETA-TRYPSIN IN COMPLEX WITH BENZAMIDINE | Descriptor: | BENZAMIDINE, CALCIUM ION, CHLORIDE ION, ... | Authors: | Ota, N, Stroupe, C, Ferreira-Da-Silva, J.M.S, Shah, S.S, Mares-Guia, M, Brunger, A.T. | Deposit date: | 1999-03-16 | Release date: | 1999-03-23 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Non-Boltzmann thermodynamic integration (NBTI) for macromolecular systems: relative free energy of binding of trypsin to benzamidine and benzylamine. Proteins, 37, 1999
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8FOZ
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![BU of 8foz by Molmil](/molmil-images/mine/8foz) | Human IMPDH2 mutant - L245P, treated with ATP, IMP, and NAD+; filament assembly interface reconstruction | Descriptor: | INOSINIC ACID, Inosine-5'-monophosphate dehydrogenase 2, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | Authors: | O'Neill, A.G, Kollman, J.M. | Deposit date: | 2023-01-03 | Release date: | 2023-04-19 | Last modified: | 2023-08-09 | Method: | ELECTRON MICROSCOPY (2 Å) | Cite: | Neurodevelopmental disorder mutations in the purine biosynthetic enzyme IMPDH2 disrupt its allosteric regulation. J.Biol.Chem., 299, 2023
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8FUZ
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![BU of 8fuz by Molmil](/molmil-images/mine/8fuz) | Human IMPDH2 mutant - L245P, treated with GTP, ATP, IMP, and NAD+; filament assembly interface reconstruction | Descriptor: | INOSINIC ACID, Inosine-5'-monophosphate dehydrogenase 2, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | Authors: | O'Neill, A.G, Kollman, J.M. | Deposit date: | 2023-01-18 | Release date: | 2023-04-19 | Last modified: | 2023-08-09 | Method: | ELECTRON MICROSCOPY (2.1 Å) | Cite: | Neurodevelopmental disorder mutations in the purine biosynthetic enzyme IMPDH2 disrupt its allosteric regulation. J.Biol.Chem., 299, 2023
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6IC4
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![BU of 6ic4 by Molmil](/molmil-images/mine/6ic4) | |
6I2D
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6I7M
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![BU of 6i7m by Molmil](/molmil-images/mine/6i7m) | Influenza A nucleoprotein docked into 3D helical structure of the wild type ribonucleoprotein complex obtained using cryoEM. Conformation 4. | Descriptor: | Nucleoprotein | Authors: | Coloma, R, Arranz, R, de la Rosa-Trevin, J.M, Sorzano, C.O.S, Carlero, D, Ortin, J, Martin-Benito, J. | Deposit date: | 2018-11-16 | Release date: | 2020-02-12 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (10 Å) | Cite: | Structural insights into influenza A virus ribonucleoproteins reveal a processive helical track as transcription mechanism. Nat Microbiol, 5, 2020
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6I2A
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![BU of 6i2a by Molmil](/molmil-images/mine/6i2a) | Crystal Structure of the Protein-Kinase A catalytic subunit from Cricetulus Griseus in complex with compounds RKp153 and Fasudil | Descriptor: | 5-(1,4-DIAZEPAN-1-SULFONYL)ISOQUINOLINE, UPF0418 protein FAM164A, beta-D-ribopyranose, ... | Authors: | Mueller, J.M, Heine, A, Klebe, G. | Deposit date: | 2018-11-01 | Release date: | 2019-05-15 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Conceptional Design of Self-Assembling Bisubstrate-like Inhibitors of Protein Kinase A Resulting in a Boronic Acid Glutamate Linkage Acs Omega, 2019
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6IA2
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![BU of 6ia2 by Molmil](/molmil-images/mine/6ia2) | Crystal structure of a self-complementary RNA duplex recognized by Com | Descriptor: | CHLORIDE ION, RNA (5'-R(*AP*GP*AP*GP*AP*AP*CP*CP*CP*GP*GP*AP*GP*UP*UP*CP*CP*CP*U)-3'), SULFATE ION | Authors: | Nowacka, M, Fernandes, H, Kiliszek, A, Bernat, A, Lach, G, Bujnicki, J.M. | Deposit date: | 2018-11-26 | Release date: | 2019-03-27 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.27 Å) | Cite: | Specific interaction of zinc finger protein Com with RNA and the crystal structure of a self-complementary RNA duplex recognized by Com. Plos One, 14, 2019
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2VXY
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![BU of 2vxy by Molmil](/molmil-images/mine/2vxy) | The structure of FTsZ from Bacillus subtilis at 1.7A resolution | Descriptor: | CELL DIVISION PROTEIN FTSZ, CITRIC ACID, POTASSIUM ION | Authors: | Barynin, V.V, Baker, P.J, Rice, D.W, Sedelnikova, S.E, Haydon, D.J, Stokes, N.R, Ure, R, Galbraith, G, Bennett, J.M, Brown, D.R, Heal, J.R, Sheridan, J.M, Aiwale, S.T, Chauhan, P.K, Srivastava, A, Taneja, A, Collins, I, Errington, J, Czaplewski, L.G. | Deposit date: | 2008-07-15 | Release date: | 2008-09-30 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | An Inhibitor of Ftsz with Potent and Selective Anti-Staphylococcal Activity. Science, 321, 2008
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6I7B
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![BU of 6i7b by Molmil](/molmil-images/mine/6i7b) | Influenza A nucleoprotein docked into 3D helical structure of the wild type ribonucleoprotein complex obtained using cryoEM. Conformation 3. | Descriptor: | Nucleoprotein | Authors: | Coloma, R, Arranz, R, de la Rosa-Trevin, J.M, Sorzano, C.O.S, Carlero, D, Ortin, J, Martin-Benito, J. | Deposit date: | 2018-11-16 | Release date: | 2020-02-19 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (10 Å) | Cite: | Structural insights into influenza A virus ribonucleoproteins reveal a processive helical track as transcription mechanism. Nat Microbiol, 5, 2020
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8JJW
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![BU of 8jjw by Molmil](/molmil-images/mine/8jjw) | Crystal structure of QG-hNTAQ1 C28S | Descriptor: | MAGNESIUM ION, Protein N-terminal glutamine amidohydrolase | Authors: | Kang, J.M, Han, B.W. | Deposit date: | 2023-05-31 | Release date: | 2024-06-26 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structural study for substrate recognition of human N-terminal glutamine amidohydrolase 1 in the arginine N-degron pathway. Protein Sci., 33, 2024
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8JJY
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![BU of 8jjy by Molmil](/molmil-images/mine/8jjy) | Crystal structure of QN-hNTAQ1 C28S | Descriptor: | Protein N-terminal glutamine amidohydrolase | Authors: | Kang, J.M, Han, B.W. | Deposit date: | 2023-05-31 | Release date: | 2024-06-26 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | Structural study for substrate recognition of human N-terminal glutamine amidohydrolase 1 in the arginine N-degron pathway. Protein Sci., 33, 2024
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8JK2
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![BU of 8jk2 by Molmil](/molmil-images/mine/8jk2) | Crystal structure of QF-hNTAQ1 C28S | Descriptor: | Protein N-terminal glutamine amidohydrolase | Authors: | Kang, J.M, Han, B.W. | Deposit date: | 2023-05-31 | Release date: | 2024-06-26 | Method: | X-RAY DIFFRACTION (1.742 Å) | Cite: | Structural study for substrate recognition of human N-terminal glutamine amidohydrolase 1 in the arginine N-degron pathway. Protein Sci., 33, 2024
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6UX8
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![BU of 6ux8 by Molmil](/molmil-images/mine/6ux8) | |