6ML3
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![BU of 6ml3 by Molmil](/molmil-images/mine/6ml3) | ZBTB24 Zinc Fingers 4-8 with 19+1mer DNA Oligonucleotide (Sequence 2) | Descriptor: | 1,2-ETHANEDIOL, DNA (5'-D(*AP*CP*GP*CP*AP*GP*GP*TP*CP*CP*TP*GP*GP*AP*AP*GP*CP*TP*AP*A)-3'), DNA (5'-D(*TP*TP*TP*AP*GP*CP*TP*TP*CP*CP*AP*GP*GP*AP*CP*CP*TP*GP*CP*G)-3'), ... | Authors: | Horton, J.R, Cheng, X, Ren, R. | Deposit date: | 2018-09-26 | Release date: | 2019-07-03 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.683 Å) | Cite: | Structural basis of specific DNA binding by the transcription factor ZBTB24. Nucleic Acids Res., 47, 2019
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5MIM
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![BU of 5mim by Molmil](/molmil-images/mine/5mim) | Xray structure of human furin bound with the 2,5-dideoxystreptamine derived small molecule inhibitor 1n | Descriptor: | 1-[(1~{R},2~{R},4~{S},5~{S})-2,4-bis(4-carbamimidamidophenoxy)-5-[(4-carbamimidamidophenyl)amino]cyclohexyl]guanidine, CALCIUM ION, CHLORIDE ION, ... | Authors: | Dahms, S.O, Guan-Sheng, J, Than, M.E. | Deposit date: | 2016-11-28 | Release date: | 2017-05-10 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural Studies Revealed Active Site Distortions of Human Furin by a Small Molecule Inhibitor. ACS Chem. Biol., 12, 2017
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8J5P
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![BU of 8j5p by Molmil](/molmil-images/mine/8j5p) | Cryo-EM structure of native RC-LH complex from Roseiflexus castenholzii at 2,000lux | Descriptor: | (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, 2-methyl-3-[(2E,6E,10E,14E,18E,22E,26E,30E,34E,38E)-3,7,11,15,19,23,27,31,35,39,43-undecamethyltetratetraconta-2,6,10,1 4,18,22,26,30,34,38,42-undecaen-1-yl]naphthalene-1,4-dione, Alpha subunit of light-harvesting 1, ... | Authors: | Xu, X, Xin, J. | Deposit date: | 2023-04-24 | Release date: | 2023-09-20 | Last modified: | 2023-10-04 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Carotenoid assembly regulates quinone diffusion and the Roseiflexus castenholzii reaction center-light harvesting complex architecture. Elife, 12, 2023
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8J5O
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![BU of 8j5o by Molmil](/molmil-images/mine/8j5o) | Cryo-EM structure of native RC-LH complex from Roseiflexus castenholzii at 100lux | Descriptor: | (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, 2-methyl-3-[(2E,6E,10E,14E,18E,22E,26E,30E,34E,38E)-3,7,11,15,19,23,27,31,35,39,43-undecamethyltetratetraconta-2,6,10,1 4,18,22,26,30,34,38,42-undecaen-1-yl]naphthalene-1,4-dione, Alpha subunit of light-harvesting 1, ... | Authors: | Xu, X, Xin, J. | Deposit date: | 2023-04-24 | Release date: | 2023-09-20 | Last modified: | 2023-10-04 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Carotenoid assembly regulates quinone diffusion and the Roseiflexus castenholzii reaction center-light harvesting complex architecture. Elife, 12, 2023
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6ML2
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![BU of 6ml2 by Molmil](/molmil-images/mine/6ml2) | ZBTB24 Zinc Fingers 4-8 with 19+1mer DNA Oligonucleotide (Sequence 1) | Descriptor: | DNA (5'-D(*AP*CP*GP*CP*AP*GP*GP*TP*CP*CP*TP*GP*GP*CP*AP*GP*CP*TP*AP*A)-3'), DNA (5'-D(*TP*TP*TP*AP*GP*CP*TP*GP*CP*CP*AP*GP*GP*AP*CP*CP*TP*GP*CP*G)-3'), ZINC ION, ... | Authors: | Horton, J.R, Cheng, X, Ren, R. | Deposit date: | 2018-09-26 | Release date: | 2019-07-03 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.874 Å) | Cite: | Structural basis of specific DNA binding by the transcription factor ZBTB24. Nucleic Acids Res., 47, 2019
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6KDL
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![BU of 6kdl by Molmil](/molmil-images/mine/6kdl) | Crystal structure of human DNMT3B-DNMT3L complex (I) | Descriptor: | DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3B, S-ADENOSYL-L-HOMOCYSTEINE | Authors: | Lin, C.-C, Chen, Y.-P, Yang, W.-Z, Shen, C.-K, Yuan, H.S. | Deposit date: | 2019-07-02 | Release date: | 2020-02-19 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.274 Å) | Cite: | Structural insights into CpG-specific DNA methylation by human DNA methyltransferase 3B. Nucleic Acids Res., 48, 2020
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6KDP
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![BU of 6kdp by Molmil](/molmil-images/mine/6kdp) | Crystal structure of human DNMT3B-DNMT3L complex (II) | Descriptor: | DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3B, FORMIC ACID, ... | Authors: | Lin, C.-C, Chen, Y.-P, Yang, W.-Z, Shen, C.-K, Yuan, H.S. | Deposit date: | 2019-07-02 | Release date: | 2020-02-19 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.93 Å) | Cite: | Structural insights into CpG-specific DNA methylation by human DNA methyltransferase 3B. Nucleic Acids Res., 48, 2020
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6ULS
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![BU of 6uls by Molmil](/molmil-images/mine/6uls) | BRD4-BD1 in complex with the a diacetylated-E2F1 peptide | Descriptor: | Bromodomain-containing protein 4, Diacetylated E2F1 Peptide (K117ac and K120ac) | Authors: | Patel, K, Low, J.K.K, Mackay, J.P. | Deposit date: | 2019-10-08 | Release date: | 2020-08-19 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | BET-Family Bromodomains Can Recognize Diacetylated Sequences from Transcription Factors Using a Conserved Mechanism. Biochemistry, 60, 2021
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8C9M
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![BU of 8c9m by Molmil](/molmil-images/mine/8c9m) | HERV-K Gag immature lattice | Descriptor: | Gag protein | Authors: | Krebs, A.-S, Liu, H.-F, Zhou, Y, Rey, J.S, Levintov, L, Perilla, J.R, Bartesaghi, A, Zhang, P. | Deposit date: | 2023-01-23 | Release date: | 2023-02-01 | Last modified: | 2023-07-05 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Molecular architecture and conservation of an immature human endogenous retrovirus. Biorxiv, 2023
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6S3S
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![BU of 6s3s by Molmil](/molmil-images/mine/6s3s) | Structure of the FliPQR complex from the flagellar type 3 secretion system of Vibrio mimicus. | Descriptor: | Flagellar biosynthetic protein FliP, Flagellar biosynthetic protein FliQ, Flagellar biosynthetic protein FliR | Authors: | Kuhlen, L, Johnson, S, Deme, J.C, Lea, S.M. | Deposit date: | 2019-06-25 | Release date: | 2020-03-25 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | The substrate specificity switch FlhB assembles onto the export gate to regulate type three secretion. Nat Commun, 11, 2020
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6S3L
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![BU of 6s3l by Molmil](/molmil-images/mine/6s3l) | Structure of the core of the flagellar export apparatus from Vibrio mimicus, the FliPQR-FlhB complex. | Descriptor: | Flagellar biosynthetic protein FlhB, Flagellar biosynthetic protein FliP, Flagellar biosynthetic protein FliQ, ... | Authors: | Kuhlen, L, Johnson, S, Deme, J.C, Lea, S.M. | Deposit date: | 2019-06-25 | Release date: | 2020-03-25 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | The substrate specificity switch FlhB assembles onto the export gate to regulate type three secretion. Nat Commun, 11, 2020
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6S3R
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![BU of 6s3r by Molmil](/molmil-images/mine/6s3r) | Structure of the FliPQR complex from the flagellar type 3 secretion system of Pseudomonas savastanoi. | Descriptor: | Flagellar biosynthetic protein FliP, Flagellar biosynthetic protein FliQ, Flagellar biosynthetic protein FliR | Authors: | Kuhlen, L, Johnson, S, Deme, J.C, Lea, S.M. | Deposit date: | 2019-06-25 | Release date: | 2020-03-25 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | The substrate specificity switch FlhB assembles onto the export gate to regulate type three secretion. Nat Commun, 11, 2020
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7W5S
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![BU of 7w5s by Molmil](/molmil-images/mine/7w5s) | A nonheme iron- and alpha-ketoglutarate- dependent halogenase that catalyzes nucleotide substrates | Descriptor: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, FE (II) ION, ... | Authors: | Dai, L.H, Zhang, X, Hu, Y.M, Huang, J.W, Chen, C.C, Guo, R.T. | Deposit date: | 2021-11-30 | Release date: | 2022-04-13 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | Structural and Functional Insights into a Nonheme Iron- and alpha-Ketoglutarate-Dependent Halogenase That Catalyzes Chlorination of Nucleotide Substrates. Appl.Environ.Microbiol., 88, 2022
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7W5V
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![BU of 7w5v by Molmil](/molmil-images/mine/7w5v) | A nonheme iron- and alpha-ketoglutarate- dependent halogenase that catalyzes nucleotide substrates | Descriptor: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, FE (III) ION, ... | Authors: | Dai, L.H, Zhang, X, Hu, Y.M, Huang, J.W, Chen, C.C, Guo, R.T. | Deposit date: | 2021-11-30 | Release date: | 2022-04-13 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.81 Å) | Cite: | Structural and Functional Insights into a Nonheme Iron- and alpha-Ketoglutarate-Dependent Halogenase That Catalyzes Chlorination of Nucleotide Substrates. Appl.Environ.Microbiol., 88, 2022
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8WIU
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![BU of 8wiu by Molmil](/molmil-images/mine/8wiu) | Bromodomain and Extra-terminal Domain (BET) BRD4 | Descriptor: | 7-[5-[1-(cyclopropylmethyl)-3,5-dimethyl-pyrazol-4-yl]pyridin-3-yl]-1~{H}-imidazo[4,5-b]pyridine, Isoform C of Bromodomain-containing protein 4 | Authors: | Cao, D, Zhiyan, D, Xiong, B. | Deposit date: | 2023-09-25 | Release date: | 2024-01-03 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Discovery of a brain-permeable bromodomain and extra terminal domain (BET) inhibitor with selectivity for BD1 for the treatment of multiple sclerosis. Eur.J.Med.Chem., 265, 2023
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8JLX
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![BU of 8jlx by Molmil](/molmil-images/mine/8jlx) | CCHFV envelope protein Gc in complex with Gc13 | Descriptor: | Glycoprotein C,CCHFV Gc fusion loops, Mouse antibody Gc13 heavy chain, Mouse antibody Gc13 light chain | Authors: | Chong, T, Cao, S. | Deposit date: | 2023-06-03 | Release date: | 2024-01-24 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Neutralizing monoclonal antibodies against the Gc fusion loop region of Crimean-Congo hemorrhagic fever virus. Plos Pathog., 20, 2024
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6JO2
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![BU of 6jo2 by Molmil](/molmil-images/mine/6jo2) | Ferredoxin I from Thermosynechococcus elongatus | Descriptor: | BENZAMIDINE, FE2/S2 (INORGANIC) CLUSTER, Ferredoxin-1, ... | Authors: | Motomura, T. | Deposit date: | 2019-03-19 | Release date: | 2019-09-18 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | An alternative plant-like cyanobacterial ferredoxin with unprecedented structural and functional properties. Biochim Biophys Acta Bioenerg, 1860, 2019
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8JLW
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![BU of 8jlw by Molmil](/molmil-images/mine/8jlw) | CCHFV envelope protein Gc in complex with Gc8 | Descriptor: | Glycoprotein C,CCHFV envelope protein Gc fusion loops, Mouse antibody Gc8 heavy chain, Mouse antibody Gc8 light chain | Authors: | Chong, T, Cao, S. | Deposit date: | 2023-06-03 | Release date: | 2024-01-24 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Neutralizing monoclonal antibodies against the Gc fusion loop region of Crimean-Congo hemorrhagic fever virus. Plos Pathog., 20, 2024
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8JKD
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![BU of 8jkd by Molmil](/molmil-images/mine/8jkd) | |
6IGZ
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![BU of 6igz by Molmil](/molmil-images/mine/6igz) | Structure of PSI-LHCI | Descriptor: | (3S,5R,6S,3'S,5'R,6'S)-5,6,5',6'-DIEPOXY-5,6,5',6'- TETRAHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, (6'R,11cis,11'cis,13cis,15cis)-4',5'-didehydro-5',6'-dihydro-beta,beta-carotene, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, ... | Authors: | Xiong, P, Xiaochun, Q. | Deposit date: | 2018-09-27 | Release date: | 2019-02-13 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.49 Å) | Cite: | Structure of a green algal photosystem I in complex with a large number of light-harvesting complex I subunits. Nat Plants, 5, 2019
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6KKH
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![BU of 6kkh by Molmil](/molmil-images/mine/6kkh) | Crystal structure of the oxalate bound malyl-CoA lyase from Roseiflexus castenholzii | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, HpcH/HpaI aldolase, MAGNESIUM ION, ... | Authors: | Tang, W.R, Wang, Z.G, Zhang, C.Y, Wang, C. | Deposit date: | 2019-07-25 | Release date: | 2019-09-04 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.64 Å) | Cite: | The C-terminal domain conformational switch revealed by the crystal structure of malyl-CoA lyase from Roseiflexus castenholzii. Biochem.Biophys.Res.Commun., 518, 2019
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5XM8
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![BU of 5xm8 by Molmil](/molmil-images/mine/5xm8) | |
8CJ8
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![BU of 8cj8 by Molmil](/molmil-images/mine/8cj8) | |
8K0S
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![BU of 8k0s by Molmil](/molmil-images/mine/8k0s) | |
8K15
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![BU of 8k15 by Molmil](/molmil-images/mine/8k15) | |