366D
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![BU of 366d by Molmil](/molmil-images/mine/366d) | 1.3 A STRUCTURE DETERMINATION OF THE D(CG(5-BRU)ACG)2/6-BROMO-9-AMINO-DACA COMPLEX | Descriptor: | 6-BROMO-9-AMINO-N-ETHYL(DIAMINOMETHYL)ACRIDINE-4-CARBOXAMIDE, DNA (5'-D(*CP*GP*(BRU)P*AP*CP*G)-3') | Authors: | Todd, A.K, Adams, A, Thorpe, J.H, Denny, W.A, Cardin, C.J. | Deposit date: | 1997-12-19 | Release date: | 1999-04-06 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Major groove binding and 'DNA-induced' fit in the intercalation of a derivative of the mixed topoisomerase I/II poison N-(2-(dimethylamino)ethyl)acridine-4-carboxamide (DACA) into DNA: X-ray structure complexed to d(CG(5-BrU)ACG)2 at 1.3-A resolution. J.Med.Chem., 42, 1999
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1QZL
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![BU of 1qzl by Molmil](/molmil-images/mine/1qzl) | GCATGCT + Cobalt | Descriptor: | 5'-D(*GP*CP*AP*TP*GP*CP*T)-3', COBALT (II) ION | Authors: | Cardin, C.J, Gan, Y, Thorpe, J.H, Teixeira, S.C.M, Gale, B.C, Moraes, M.I.A. | Deposit date: | 2003-09-17 | Release date: | 2003-10-21 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Metal Ion Distribution and Stabilisation of the DNA Quadruplex Structure Formed by d(GCATGCT) To be published
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1QYL
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![BU of 1qyl by Molmil](/molmil-images/mine/1qyl) | GCATGCT + Vanadium | Descriptor: | 5'-D(*GP*CP*AP*TP*GP*CP*T)-3', VANADIUM ION | Authors: | Cardin, C.J, Gan, Y, Thorpe, J.H, Teixeira, S.C.M, Gale, B.C, Moraes, M.I.A. | Deposit date: | 2003-09-11 | Release date: | 2003-10-21 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1 Å) | Cite: | Metal Ion Distribution and Stabilisation of the DNA Quadruplex Structure Formed by d(GCATGCT) To be Published
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1NT8
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![BU of 1nt8 by Molmil](/molmil-images/mine/1nt8) | Structural Characterisation of the Holliday junction formed by the sequence CCGGTACCGG at 2.00 A | Descriptor: | 5'-d(CpCpGpGpTpApCpCpGpG)-3', CALCIUM ION | Authors: | Cardin, C.J, Gale, B.C, Thorpe, J.H, Texieira, S.C.M, Gan, Y, Moraes, M.I.A.A, Brogden, A.L. | Deposit date: | 2003-01-29 | Release date: | 2003-02-11 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural Analysis of two Holliday Junctions formed by the sequences TCGGTACCGA and CCGGTACCGG To be Published
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1QYK
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![BU of 1qyk by Molmil](/molmil-images/mine/1qyk) | GCATGCT + Barium | Descriptor: | 5'-D(*GP*CP*AP*TP*GP*CP*T)-3', BARIUM ION | Authors: | Cardin, C.J, Gan, Y, Thorpe, J.H, Teixeira, S.C.M, Gale, B.C, Moraes, M.I.A. | Deposit date: | 2003-09-11 | Release date: | 2003-10-21 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Metal Ion Distribution and Stabilization of the DNA Quadruplex Structure Formed by d(GCATGCT) To be published
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1R2O
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![BU of 1r2o by Molmil](/molmil-images/mine/1r2o) | d(GCATGCT) + Ni2+ | Descriptor: | 5'-D(*GP*CP*AP*TP*GP*CP*T)-3', NICKEL (II) ION | Authors: | Cardin, J.C, Gan, Y, Thorpe, J.H, Teixeira, S.C.M, Gale, B.C, Moraes, M.I.A. | Deposit date: | 2003-09-29 | Release date: | 2003-10-21 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.38 Å) | Cite: | Metal Ion Distribution and Stabilization of the DNA Quadruplex Structure Formed by d(GCATGCT) To be published
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1M69
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![BU of 1m69 by Molmil](/molmil-images/mine/1m69) | |
1NQS
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![BU of 1nqs by Molmil](/molmil-images/mine/1nqs) | Structural Characterisation of the Holliday Junction formed by the sequence d(TCGGTACCGA) at 1.97 A | Descriptor: | 5'-d(TpCpGpGpTpApCpCpGpA)-3', CALCIUM ION | Authors: | Cardin, C.J, Gale, B.C, Thorpe, J.H, Texieira, S.C.M, Gan, Y, Moraes, M.I.A.A, Brogden, A.L. | Deposit date: | 2003-01-22 | Release date: | 2003-02-04 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Structural Analysis of two Holliday junctions formed by the sequences TCGGTACCGA and CCGGTACCGG To be Published
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1NVY
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![BU of 1nvy by Molmil](/molmil-images/mine/1nvy) | |
1NVN
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![BU of 1nvn by Molmil](/molmil-images/mine/1nvn) | Structural Characterisation of the Holliday junction formed by the sequence CCGGTACCGG at 1.8 A | Descriptor: | 5'-D(CpCpGpGpTpApCpCpGpG)-3', CALCIUM ION | Authors: | Cardin, C.J, Gale, B.C, Thorpe, J.H, Teixeira, S.C.M, Gan, Y, Moraes, M.I.A.A, Brogden, A.L. | Deposit date: | 2003-02-04 | Release date: | 2003-02-25 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural analysis of two Holliday junctions formed by the sequences TCGGTACCGA and CCGGTACCGG To be Published
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7A16
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![BU of 7a16 by Molmil](/molmil-images/mine/7a16) | |
7A14
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![BU of 7a14 by Molmil](/molmil-images/mine/7a14) | |
7A15
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![BU of 7a15 by Molmil](/molmil-images/mine/7a15) | |
7A13
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![BU of 7a13 by Molmil](/molmil-images/mine/7a13) | |
7A12
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![BU of 7a12 by Molmil](/molmil-images/mine/7a12) | |
3T86
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![BU of 3t86 by Molmil](/molmil-images/mine/3t86) | d(GCATGCT) + calcium | Descriptor: | CALCIUM ION, DNA (5'-D(*GP*CP*AP*TP*GP*CP*T)-3'), POTASSIUM ION | Authors: | Cardin, C.J, Gan, Y. | Deposit date: | 2011-08-01 | Release date: | 2012-06-13 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | A novel structure for the d(GCATGCT) quadruplex in the presence of nickel and cobalt aqueous cations : comparison with the vanadium, barium and calcium-bound structural motif. To be Published
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344D
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![BU of 344d by Molmil](/molmil-images/mine/344d) | DETERMINATION BY MAD-DM OF THE STRUCTURE OF THE DNA DUPLEX D(ACGTACG(5-BRU))2 AT 1.46A AND 100K | Descriptor: | DNA (5'-D(*AP*CP*GP*TP*AP*CP*GP*(BRU))-3') | Authors: | Todd, A.R, Adams, A, Powell, H.R, Cardin, C.J. | Deposit date: | 1997-08-04 | Release date: | 1997-09-26 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (1.46 Å) | Cite: | Determination by MAD-DM of the structure of the DNA duplex d[ACGTACG(5-BrU)]2 at 1.46 A and 100 K. Acta Crystallogr.,Sect.D, 55, 1999
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2UWP
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![BU of 2uwp by Molmil](/molmil-images/mine/2uwp) | Factor Xa inhibitor complex | Descriptor: | 2-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}ETHANESULFONAMIDE, CALCIUM ION, COAGULATION FACTOR X, ... | Authors: | Young, R.J, Brown, D, Burns-Kurtis, C.L, Chan, C, Convery, M.A, Hubbard, J.A, Kelly, H.A, Pateman, A.J, Patikis, A, Senger, S, Shah, G.P, Toomey, J.R, Watson, N.S, Zhou, P, Thorpe, J.H. | Deposit date: | 2007-03-22 | Release date: | 2007-05-08 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Selective and Dual Action Orally Active Inhibitors of Thrombin and Factor Xa. Bioorg.Med.Chem.Lett., 17, 2007
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