5E9T
| Crystal structure of GtfA/B complex | Descriptor: | Glycosyltransferase Gtf1, Glycosyltransferase-stabilizing protein Gtf2, MAGNESIUM ION | Authors: | Chen, Y, Rapoport, T.A. | Deposit date: | 2015-10-15 | Release date: | 2016-03-02 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.92 Å) | Cite: | Mechanism of a cytosolic O-glycosyltransferase essential for the synthesis of a bacterial adhesion protein. Proc.Natl.Acad.Sci.USA, 113, 2016
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5E9U
| Crystal structure of GtfA/B complex bound to UDP and GlcNAc | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Glycosyltransferase Gtf1, Glycosyltransferase-stabilizing protein Gtf2, ... | Authors: | Chen, Y, Rapoport, T.A. | Deposit date: | 2015-10-15 | Release date: | 2016-03-02 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (3.84 Å) | Cite: | Mechanism of a cytosolic O-glycosyltransferase essential for the synthesis of a bacterial adhesion protein. Proc.Natl.Acad.Sci.USA, 113, 2016
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5EUL
| Structure of the SecA-SecY complex with a translocating polypeptide substrate | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, AYC08, BERYLLIUM TRIFLUORIDE ION, ... | Authors: | Li, L, Park, E, Ling, J, Ingram, J, Ploegh, H, Rapoport, T.A. | Deposit date: | 2015-11-18 | Release date: | 2016-03-09 | Last modified: | 2019-12-25 | Method: | X-RAY DIFFRACTION (3.7 Å) | Cite: | Crystal structure of a substrate-engaged SecY protein-translocation channel. Nature, 531, 2016
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3J45
| Structure of a non-translocating SecY protein channel with the 70S ribosome | Descriptor: | 23S ribosomal RNA, 50S ribosomal protein L23, 50S ribosomal protein L24, ... | Authors: | Menetret, J.F, Park, E, Gumbart, J.C, Ludtke, S.J, Li, W, Whynot, A, Rapoport, T.A, Akey, C.W. | Deposit date: | 2013-06-18 | Release date: | 2013-10-23 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (9.5 Å) | Cite: | Structure of the SecY channel during initiation of protein translocation. Nature, 506, 2013
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3J46
| Structure of the SecY protein translocation channel in action | Descriptor: | 23S ribosomal RNA, 50S ribosomal protein L1, 50S ribosomal protein L23P, ... | Authors: | Akey, C.W, Park, E, Menetret, J.F, Gumbart, J.C, Ludtke, S.J, Li, W, Whynot, A, Rapoport, T.A. | Deposit date: | 2013-06-18 | Release date: | 2013-10-23 | Last modified: | 2019-07-03 | Method: | ELECTRON MICROSCOPY (10.1 Å) | Cite: | Structure of the SecY channel during initiation of protein translocation. Nature, 506, 2013
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3DL8
| Structure of the complex of aquifex aeolicus SecYEG and bacillus subtilis SecA | Descriptor: | Preprotein translocase subunit secY, Protein translocase subunit secA, Protein-export membrane protein secG, ... | Authors: | Nam, Y, Zimmer, J, Rapoport, T.A. | Deposit date: | 2008-06-26 | Release date: | 2008-12-02 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (7.5 Å) | Cite: | Structure of a complex of the ATPase SecA and the protein-translocation channel. Nature, 455, 2008
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3DIN
| Crystal structure of the protein-translocation complex formed by the SecY channel and the SecA ATPase | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ... | Authors: | Zimmer, J, Nam, Y, Rapoport, T.A. | Deposit date: | 2008-06-20 | Release date: | 2008-10-07 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (4.5 Å) | Cite: | Structure of a complex of the ATPase SecA and the protein-translocation channel. Nature, 455, 2008
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5V6P
| CryoEM structure of the ERAD-associated E3 ubiquitin-protein ligase HRD1 | Descriptor: | ERAD-associated E3 ubiquitin-protein ligase HRD1 | Authors: | Schoebel, S, Mi, W, Stein, A, Rapoport, T.A, Liao, M. | Deposit date: | 2017-03-17 | Release date: | 2017-08-16 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Cryo-EM structure of the protein-conducting ERAD channel Hrd1 in complex with Hrd3. Nature, 548, 2017
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5VAE
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5VAF
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5V7V
| Cryo-EM structure of ERAD-associated E3 ubiquitin-protein ligase component HRD3 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ERAD-associated E3 ubiquitin-protein ligase component HRD3, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Mi, W, Schoebel, S, Stein, A, Rapoport, T.A, Liao, M. | Deposit date: | 2017-03-20 | Release date: | 2017-08-16 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Cryo-EM structure of the protein-conducting ERAD channel Hrd1 in complex with Hrd3. Nature, 548, 2017
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6VK3
| CryoEM structure of Hrd3/Yos9 complex | Descriptor: | Hrd3, Protein OS-9 homolog | Authors: | Wu, X, Rapoport, T.A. | Deposit date: | 2020-01-18 | Release date: | 2020-04-29 | Last modified: | 2020-05-06 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structural basis of ER-associated protein degradation mediated by the Hrd1 ubiquitin ligase complex. Science, 368, 2020
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6VJZ
| CryoEM structure of Hrd1-Usa1/Der1/Hrd3 complex of the expected topology | Descriptor: | Degradation in the endoplasmic reticulum protein 1, ERAD-associated E3 ubiquitin-protein ligase HRD1, ERAD-associated E3 ubiquitin-protein ligase component HRD3, ... | Authors: | Wu, X, Rapoport, T.A. | Deposit date: | 2020-01-18 | Release date: | 2020-04-29 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Structural basis of ER-associated protein degradation mediated by the Hrd1 ubiquitin ligase complex. Science, 368, 2020
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6VK1
| CryoEM structure of Hrd1/Hrd3 part from Hrd1-Usa1/Der1/Hrd3 complex | Descriptor: | ERAD-associated E3 ubiquitin-protein ligase HRD1, ERAD-associated E3 ubiquitin-protein ligase component HRD3 | Authors: | Wu, X, Rapoport, T.A. | Deposit date: | 2020-01-18 | Release date: | 2020-04-29 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structural basis of ER-associated protein degradation mediated by the Hrd1 ubiquitin ligase complex. Science, 368, 2020
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6VK0
| CryoEM structure of Hrd1-Usa1/Der1/Hrd3 of the flipped topology | Descriptor: | Degradation in the endoplasmic reticulum protein 1, ERAD-associated E3 ubiquitin-protein ligase HRD1, ERAD-associated E3 ubiquitin-protein ligase component HRD3, ... | Authors: | Wu, X, Rapoport, T.A. | Deposit date: | 2020-01-18 | Release date: | 2020-04-29 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Structural basis of ER-associated protein degradation mediated by the Hrd1 ubiquitin ligase complex. Science, 368, 2020
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6VJY
| Cryo-EM structure of Hrd1/Hrd3 monomer | Descriptor: | ERAD-associated E3 ubiquitin-protein ligase HRD1, ERAD-associated E3 ubiquitin-protein ligase component HRD3 | Authors: | Wu, X, Rapoport, T.A. | Deposit date: | 2020-01-18 | Release date: | 2020-04-29 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Structural basis of ER-associated protein degradation mediated by the Hrd1 ubiquitin ligase complex. Science, 368, 2020
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1RHZ
| The structure of a protein conducting channel | Descriptor: | Preprotein translocase secE subunit, Preprotein translocase secY subunit, SecBeta | Authors: | van den Berg, B, Clemons Jr, W.M, Collinson, I, Modis, Y, Hartmann, E, Harrison, S.C, Rapoport, T.A. | Deposit date: | 2003-11-15 | Release date: | 2004-01-06 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | X-ray structure of a protein-conducting channel. Nature, 427, 2004
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1RH5
| The structure of a protein conducting channel | Descriptor: | Preprotein translocase secE subunit, Preprotein translocase secY subunit, SecBeta | Authors: | van den Berg, B, Clemons Jr, W.M, Collinson, I, Modis, Y, Hartmann, E, Harrison, S.C, Rapoport, T.A. | Deposit date: | 2003-11-13 | Release date: | 2004-01-06 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | X-ray structure of a protein-conducting channel Nature, 427, 2004
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1TF5
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1T1L
| Crystal structure of the long-chain fatty acid transporter FadL | Descriptor: | LAURYL DIMETHYLAMINE-N-OXIDE, Long-chain fatty acid transport protein | Authors: | van den Berg, B, Black, P.N, Clemons Jr, W.M, Rapoport, T.A. | Deposit date: | 2004-04-16 | Release date: | 2004-06-15 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of the long-chain fatty acid transporter FadL. Science, 304, 2004
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1T16
| Crystal structure of the bacterial fatty acid transporter FadL from Escherichia coli | Descriptor: | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, COPPER (II) ION, LAURYL DIMETHYLAMINE-N-OXIDE, ... | Authors: | van den Berg, B, Black, P.N, Clemons Jr, W.M, Rapoport, T.A. | Deposit date: | 2004-04-15 | Release date: | 2004-06-15 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structure of the long-chain fatty acid transporter FadL. Science, 304, 2004
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1TF2
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7T9X
| Saccharomyces cerevisiae Pex12 RING domain | Descriptor: | Peroxisome assembly protein 12, ZINC ION | Authors: | Feng, P, Rapoport, T. | Deposit date: | 2021-12-20 | Release date: | 2022-06-29 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.52 Å) | Cite: | A peroxisomal ubiquitin ligase complex forms a retrotranslocation channel. Nature, 607, 2022
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7T92
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3BO1
| Ribosome-SecY complex | Descriptor: | 23S RIBOSOMAL RNA, PREPROTEIN TRANSLOCASE SecE SUBUNIT, PREPROTEIN TRANSLOCASE SecY SUBUNIT, ... | Authors: | Akey, C.W, Menetret, J.F. | Deposit date: | 2007-12-15 | Release date: | 2008-12-09 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (9.6 Å) | Cite: | Ribosome binding of a single copy of the SecY complex: implications for protein translocation Mol.Cell, 28, 2007
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