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1YJM
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BU of 1yjm by Molmil
Crystal structure of the FHA domain of mouse polynucleotide kinase in complex with an XRCC4-derived phosphopeptide.
Descriptor: 12-mer peptide from DNA-repair protein XRCC4, Polynucleotide 5'-hydroxyl-kinase
Authors:Bernstein, N.K, Williams, R.S, Rakovszky, M.L, Cui, D, Green, R, Karimi-Busheri, F, Mani, R.S, Galicia, S, Koch, C.A, Cass, C.E, Durocher, D, Weinfeld, M, Glover, J.N.M.
Deposit date:2005-01-14
Release date:2005-03-15
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The molecular architecture of the mammalian DNA repair enzyme, polynucleotide kinase.
Mol.Cell, 17, 2005
3U7G
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BU of 3u7g by Molmil
Crystal structure of mPNKP catalytic fragment (D170A) bound to single-stranded DNA (TCCTAp)
Descriptor: Bifunctional polynucleotide phosphatase/kinase, DNA, GLYCEROL, ...
Authors:Coquelle, N, Havali, Z, Bernstein, N, Green, R, Glover, J.N.M.
Deposit date:2011-10-13
Release date:2011-12-14
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis for the phosphatase activity of polynucleotide kinase/phosphatase on single- and double-stranded DNA substrates.
Proc.Natl.Acad.Sci.USA, 108, 2011
3U7E
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BU of 3u7e by Molmil
Crystal structure of mPNKP catalytic fragment (D170A)
Descriptor: Bifunctional polynucleotide phosphatase/kinase, GLYCEROL, MAGNESIUM ION, ...
Authors:Coquelle, N, Havali, Z, Bernstein, N, Green, R, Glover, J.N.M.
Deposit date:2011-10-13
Release date:2011-12-14
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural basis for the phosphatase activity of polynucleotide kinase/phosphatase on single- and double-stranded DNA substrates.
Proc.Natl.Acad.Sci.USA, 108, 2011
3U7F
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BU of 3u7f by Molmil
Crystal structure of mPNKP catalytic fragment (D170A) bound to single-stranded DNA (TCCTCp)
Descriptor: Bifunctional polynucleotide phosphatase/kinase, DNA, GLYCEROL, ...
Authors:Coquelle, N, Havali, Z, Bernstein, N, Green, R, Glover, J.N.M.
Deposit date:2011-10-13
Release date:2011-12-14
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for the phosphatase activity of polynucleotide kinase/phosphatase on single- and double-stranded DNA substrates.
Proc.Natl.Acad.Sci.USA, 108, 2011
3U7H
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BU of 3u7h by Molmil
Crystal structure of mPNKP catalytic fragment (D170A) bound to single-stranded DNA (TCCTTp)
Descriptor: Bifunctional polynucleotide phosphatase/kinase, DNA, GLYCEROL, ...
Authors:Coquelle, N, Havali, Z, Bernstein, N, Green, R, Glover, J.N.M.
Deposit date:2011-10-13
Release date:2011-12-14
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for the phosphatase activity of polynucleotide kinase/phosphatase on single- and double-stranded DNA substrates.
Proc.Natl.Acad.Sci.USA, 108, 2011
3K0H
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BU of 3k0h by Molmil
The crystal structure of BRCA1 BRCT in complex with a minimal recognition tetrapeptide with an amidated C-terminus
Descriptor: Breast cancer type 1 susceptibility protein, CHLORIDE ION, NICKEL (II) ION, ...
Authors:Campbell, S.J, Edwards, R.A, Glover, J.N.
Deposit date:2009-09-24
Release date:2010-03-02
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Comparison of the Structures and Peptide Binding Specificities of the BRCT Domains of MDC1 and BRCA1
Structure, 18, 2010
3K15
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BU of 3k15 by Molmil
Crystal Structure of BRCA1 BRCT D1840T in complex with a minimal recognition tetrapeptide with an amidated C-terminus
Descriptor: Breast cancer type 1 susceptibility protein, CHLORIDE ION, NICKEL (II) ION, ...
Authors:Campbell, S.J, Edwards, R.A, Glover, J.N.
Deposit date:2009-09-25
Release date:2010-03-02
Last modified:2021-10-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Comparison of the Structures and Peptide Binding Specificities of the BRCT Domains of MDC1 and BRCA1
Structure, 18, 2010
3K05
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BU of 3k05 by Molmil
The crystal structure of MDC1 BRCT T2067D in complex with a minimal recognition tetrapeptide with an amidated C-terminus
Descriptor: GLYCEROL, Mediator of DNA damage checkpoint protein 1, phospho peptide
Authors:Campbell, S.J, Edwards, R.A, Glover, J.N.
Deposit date:2009-09-24
Release date:2010-03-02
Last modified:2021-10-13
Method:X-RAY DIFFRACTION (1.33 Å)
Cite:Comparison of the Structures and Peptide Binding Specificities of the BRCT Domains of MDC1 and BRCA1
Structure, 18, 2010
3K0K
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BU of 3k0k by Molmil
Crystal Structure of BRCA1 BRCT in complex with a minimal recognition tetrapeptide with a free carboxy C-terminus.
Descriptor: Breast cancer type 1 susceptibility protein, CHLORIDE ION, NICKEL (II) ION, ...
Authors:Campbell, S.J, Edwards, R.A, Glover, J.N.
Deposit date:2009-09-24
Release date:2010-03-02
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Comparison of the Structures and Peptide Binding Specificities of the BRCT Domains of MDC1 and BRCA1
Structure, 18, 2010
3K16
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BU of 3k16 by Molmil
Crystal Structure of BRCA1 BRCT D1840T in complex with a minimal recognition tetrapeptide with a free carboxy C-terminus
Descriptor: Breast cancer type 1 susceptibility protein, CHLORIDE ION, NICKEL (II) ION, ...
Authors:Campbell, S.J, Edwards, R.A, Glover, J.N.
Deposit date:2009-09-25
Release date:2010-03-02
Last modified:2021-10-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Comparison of the Structures and Peptide Binding Specificities of the BRCT Domains of MDC1 and BRCA1
Structure, 18, 2010
3JVE
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BU of 3jve by Molmil
Crystal Structure of the Sixth BRCT Domain of TopBP1
Descriptor: DNA topoisomerase 2-binding protein 1
Authors:Leung, C.C, Kellogg, E, Baker, D, Glover, J.N.M.
Deposit date:2009-09-16
Release date:2010-01-19
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.34 Å)
Cite:Insights from the crystal structure of the sixth BRCT domain of topoisomerase IIbeta binding protein 1.
Protein Sci., 19, 2010
2EVH
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BU of 2evh by Molmil
Structure of a Ndt80-DNA complex (MSE mutant mA7G)
Descriptor: 5'-D(*AP*GP*TP*TP*TP*CP*TP*GP*TP*GP*TP*CP*GP*C)-3', 5'-D(*TP*GP*CP*GP*AP*CP*AP*CP*AP*GP*AP*AP*AP*C)-3', NDT80 protein
Authors:Lamoureux, J.S, Glover, J.N.
Deposit date:2005-10-31
Release date:2006-03-21
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.989 Å)
Cite:Principles of Protein-DNA Recognition Revealed in the Structural Analysis of Ndt80-MSE DNA Complexes.
Structure, 14, 2006
2EUZ
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BU of 2euz by Molmil
Structure of a Ndt80-DNA complex (MSE mutant mC5T)
Descriptor: 5'-D(*AP*GP*TP*TP*TP*TP*TP*AP*TP*GP*TP*CP*GP*C)-3', 5'-D(*TP*GP*CP*GP*AP*CP*AP*TP*AP*AP*AP*AP*AP*C)-3', NDT80 protein
Authors:Lamoureux, J.S, Glover, J.N.
Deposit date:2005-10-30
Release date:2006-03-21
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Principles of Protein-DNA Recognition Revealed in the Structural Analysis of Ndt80-MSE DNA Complexes.
Structure, 14, 2006
2EVI
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BU of 2evi by Molmil
Structure of a Ndt80-DNA complex (MSE mutant mA8T)
Descriptor: 5'-D(*AP*GP*TP*TP*AP*TP*TP*GP*TP*GP*TP*CP*GP*C)-3', 5'-D(*TP*GP*CP*GP*AP*CP*AP*CP*AP*AP*TP*AP*AP*C)-3', NDT80 protein
Authors:Lamoureux, J.S, Glover, J.N.
Deposit date:2005-10-31
Release date:2006-03-21
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Principles of Protein-DNA Recognition Revealed in the Structural Analysis of Ndt80-MSE DNA Complexes.
Structure, 14, 2006
2EUX
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BU of 2eux by Molmil
Structure of a Ndt80-DNA complex (MSE VARIANT vA4G)
Descriptor: 5'-D(*AP*GP*TP*TP*TP*TP*TP*GP*CP*GP*TP*CP*GP*C)-3', 5'-D(*TP*GP*CP*GP*AP*CP*GP*CP*AP*AP*AP*AP*AP*C)-3', NDT80 protein
Authors:Lamoureux, J.S, Glover, J.N.
Deposit date:2005-10-30
Release date:2006-03-21
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Principles of Protein-DNA Recognition Revealed in the Structural Analysis of Ndt80-MSE DNA Complexes.
Structure, 14, 2006
2EUV
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BU of 2euv by Molmil
Principles of protein-DNA recognition revealed in the structural analysis of Ndt80-MSE DNA complexes
Descriptor: 5'-D(*AP*GP*TP*AP*TP*TP*TP*GP*TP*GP*TP*TP*GP*C)-3', 5'-D(*TP*GP*CP*AP*AP*CP*AP*CP*AP*AP*AP*TP*AP*C)-3', NDT80 protein
Authors:Lamoureux, J.S, Glover, J.N.
Deposit date:2005-10-30
Release date:2006-03-21
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Principles of Protein-DNA Recognition Revealed in the Structural Analysis of Ndt80-MSE DNA Complexes.
Structure, 14, 2006
2EUW
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BU of 2euw by Molmil
Structure of a Ndt80-DNA complex (MSE mutant mA4T)
Descriptor: 5'-D(*AP*GP*TP*TP*TP*TP*TP*GP*AP*GP*TP*CP*GP*C)-3', 5'-D(*TP*GP*CP*GP*AP*CP*TP*CP*AP*AP*AP*AP*AP*C)-3', NDT80 protein
Authors:Lamoureux, J.S, Glover, J.N.
Deposit date:2005-10-30
Release date:2006-03-21
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Principles of Protein-DNA Recognition Revealed in the Structural Analysis of Ndt80-MSE DNA Complexes.
Structure, 14, 2006
2EVG
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BU of 2evg by Molmil
Structure of a Ndt80-DNA complex (MSE mutant mA7T)
Descriptor: 5'-D(*AP*GP*TP*TP*TP*AP*TP*GP*TP*GP*TP*CP*GP*C)-3', 5'-D(*TP*GP*CP*GP*AP*CP*AP*CP*AP*TP*AP*AP*AP*C)-3', NDT80 protein
Authors:Lamoureux, J.S, Glover, J.N.
Deposit date:2005-10-31
Release date:2006-03-21
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Principles of Protein-DNA Recognition Revealed in the Structural Analysis of Ndt80-MSE DNA Complexes.
Structure, 14, 2006
2EVF
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BU of 2evf by Molmil
Structure of a Ndt80-DNA complex (MSE mutant mA6T)
Descriptor: 5'-D(*AP*GP*TP*TP*TP*TP*AP*GP*TP*GP*TP*CP*GP*C)-3', 5'-D(*TP*GP*CP*GP*AP*CP*AP*CP*TP*AP*AP*AP*AP*C)-3', NDT80 protein
Authors:Lamoureux, J.S, Glover, J.N.
Deposit date:2005-10-31
Release date:2006-03-21
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Principles of Protein-DNA Recognition Revealed in the Structural Analysis of Ndt80-MSE DNA Complexes.
Structure, 14, 2006
2ETW
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BU of 2etw by Molmil
Principles of protein-DNA recognition revealed in the structural analysis of Ndt80-MSE DNA complexes
Descriptor: 5'-D(*AP*GP*TP*TP*TP*TP*TP*GP*TP*GP*TP*GP*GP*C)-3', 5'-D(*TP*GP*CP*CP*AP*CP*AP*CP*AP*AP*AP*AP*AP*C)-3', NDT80 protein
Authors:Lamoureux, J.S, Glover, J.N.
Deposit date:2005-10-27
Release date:2006-03-21
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Principles of Protein-DNA Recognition Revealed in the Structural Analysis of Ndt80-MSE DNA Complexes.
Structure, 14, 2006
2EVJ
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BU of 2evj by Molmil
Structure of an Ndt80-DNA complex (MSE mutant mA9C)
Descriptor: 5'-D(*AP*GP*TP*GP*TP*TP*TP*GP*TP*GP*TP*CP*GP*C)-3', 5'-D(*TP*GP*CP*GP*AP*CP*AP*CP*AP*AP*AP*CP*AP*C)-3', NDT80 protein
Authors:Lamoureux, J.S, Glover, J.N.
Deposit date:2005-10-31
Release date:2006-03-21
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Principles of Protein-DNA Recognition Revealed in the Structural Analysis of Ndt80-MSE DNA Complexes.
Structure, 14, 2006
2G7O
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BU of 2g7o by Molmil
Protonation-mediated structural flexibility in the F conjugation regulatory protein, TraM
Descriptor: Protein traM
Authors:Lu, J, Edwards, R.A, Wong, J.J, Manchak, J, Scott, P.G, Frost, L.S, Glover, J.N.
Deposit date:2006-02-28
Release date:2006-06-13
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Protonation-mediated structural flexibility in the F conjugation regulatory protein, TraM.
Embo J., 25, 2006
3QZC
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BU of 3qzc by Molmil
Structure of the periplasmic stress response protein CpxP
Descriptor: Periplasmic protein CpxP, ZINC ION
Authors:Thede, G.L, Edwards, R.A, Glover, J.N.M.
Deposit date:2011-03-04
Release date:2011-03-23
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structure of the Periplasmic Stress Response Protein CpxP.
J.Bacteriol., 193, 2011
4ONL
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BU of 4onl by Molmil
Crystal structure of human Mms2/Ubc13_D81N, R85S, A122V, N123P
Descriptor: Ubiquitin-conjugating enzyme E2 N, Ubiquitin-conjugating enzyme E2 variant 2
Authors:Hodge, C.D, Edwards, R.A, Glover, J.N.M.
Deposit date:2014-01-28
Release date:2015-05-06
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Covalent Inhibition of Ubc13 Affects Ubiquitin Signaling and Reveals Active Site Elements Important for Targeting.
Acs Chem.Biol., 10, 2015
4OFB
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BU of 4ofb by Molmil
Crystal structure of human BRCA1 BRCT in complex with nonphosphopeptide inhibitor
Descriptor: Breast cancer type 1 susceptibility protein, nonphosphopeptide inhibitor
Authors:Sun, L, Edwards, R.A, Glover, J.N.M.
Deposit date:2014-01-14
Release date:2015-04-15
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Peptide Library Approach to Uncover Phosphomimetic Inhibitors of the BRCA1 C-Terminal Domain.
Acs Chem.Biol., 10, 2015

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数据于2024-08-14公开中

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