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7MRV
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BU of 7mrv by Molmil
F100A mutant structure of MIF2 (D-DT)
Descriptor: D-dopachrome decarboxylase, SULFATE ION
Authors:Murphy, E.L, Manjula, R, Murphy, J.W, Lolis, E.
Deposit date:2021-05-09
Release date:2021-08-18
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:A structurally preserved allosteric site in the MIF superfamily affects enzymatic activity and CD74 activation in D-dopachrome tautomerase.
J.Biol.Chem., 297, 2021
5JPE
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BU of 5jpe by Molmil
Yeast-specific serine/threonine protein phosphatase (PPZ1) of Candida albicans
Descriptor: CITRATE ANION, GLYCEROL, Serine/threonine-protein phosphatase
Authors:Choy, M.S, Chen, E.H, Peti, W, Page, R.
Deposit date:2016-05-03
Release date:2016-08-31
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.611 Å)
Cite:Molecular Insights into the Fungus-Specific Serine/Threonine Protein Phosphatase Z1 in Candida albicans.
Mbio, 7, 2016
5JPF
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BU of 5jpf by Molmil
Serine/Threonine phosphatase Z1 (Candida albicans) binds to inhibitor microcystin-LR
Descriptor: MALONATE ION, MANGANESE (II) ION, Microcystin-LR, ...
Authors:Choy, M.S, Chen, E.H, Peti, W, Page, R.
Deposit date:2016-05-03
Release date:2016-08-31
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.39929724 Å)
Cite:Molecular Insights into the Fungus-Specific Serine/Threonine Protein Phosphatase Z1 in Candida albicans.
Mbio, 7, 2016
4K2U
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BU of 4k2u by Molmil
Crystal structure of PfEBA-175 F1 in complex with R218 antibody Fab fragment
Descriptor: Antibody Heavy Chain, Antibody Light Chain, Erythrocyte binding antigen 175, ...
Authors:Tolia, N.H.
Deposit date:2013-04-09
Release date:2013-06-12
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structural and Functional Basis for Inhibition of Erythrocyte Invasion by Antibodies that Target Plasmodium falciparum EBA-175.
Plos Pathog., 9, 2013
8WZX
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BU of 8wzx by Molmil
Cryo-EM structure of the hamster prion 23-144 fibril at pH 3.7
Descriptor: Major prion protein
Authors:Lee, C.-H, Saw, J.-E, Chen, E, Wang, C.-H, Chen, R.
Deposit date:2023-11-02
Release date:2024-05-01
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (2.88 Å)
Cite:The Positively Charged Cluster in the N-terminal Disordered Region may Affect Prion Protein Misfolding: Cryo-EM Structure of Hamster PrP(23-144) Fibrils.
J.Mol.Biol., 436, 2024
8EKD
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BU of 8ekd by Molmil
Cryo-EM map of SARS-CoV-2 Omicron BA.2 spike in complex with 2130-1-0114-112
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab LLNL-199 HC, Fab LLNL-199 LC, ...
Authors:Binshtein, E, Crowe, J.E.
Deposit date:2022-09-20
Release date:2024-02-21
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Computationally restoring the potency of a clinical antibody against Omicron.
Nature, 629, 2024
1HSI
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BU of 1hsi by Molmil
CRYSTAL STRUCTURE AT 1.9 ANGSTROMS RESOLUTION OF HUMAN IMMUNODEFICIENCY VIRUS (HIV) II PROTEASE COMPLEXED WITH L-735,524, AN ORALLY BIOAVAILABLE INHIBITOR OF THE HIV PROTEASES
Descriptor: HIV-2 PROTEASE
Authors:Chen, Z.
Deposit date:1995-03-31
Release date:1996-04-03
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure at 1.9-A resolution of human immunodeficiency virus (HIV) II protease complexed with L-735,524, an orally bioavailable inhibitor of the HIV proteases.
J.Biol.Chem., 269, 1994
1HSG
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BU of 1hsg by Molmil
CRYSTAL STRUCTURE AT 1.9 ANGSTROMS RESOLUTION OF HUMAN IMMUNODEFICIENCY VIRUS (HIV) II PROTEASE COMPLEXED WITH L-735,524, AN ORALLY BIOAVAILABLE INHIBITOR OF THE HIV PROTEASES
Descriptor: HIV-1 PROTEASE, N-[2(R)-HYDROXY-1(S)-INDANYL]-5-[(2(S)-TERTIARY BUTYLAMINOCARBONYL)-4(3-PYRIDYLMETHYL)PIPERAZINO]-4(S)-HYDROXY-2(R)-PHENYLMETHYLPENTANAMIDE
Authors:Chen, Z.
Deposit date:1995-03-31
Release date:1996-04-03
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure at 1.9-A resolution of human immunodeficiency virus (HIV) II protease complexed with L-735,524, an orally bioavailable inhibitor of the HIV proteases.
J.Biol.Chem., 269, 1994
1HSH
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BU of 1hsh by Molmil
CRYSTAL STRUCTURE AT 1.9 ANGSTROMS RESOLUTION OF HUMAN IMMUNODEFICIENCY VIRUS (HIV) II PROTEASE COMPLEXED WITH L-735,524, AN ORALLY BIOAVAILABLE INHIBITOR OF THE HIV PROTEASES
Descriptor: HIV-II PROTEASE, N-[2(R)-HYDROXY-1(S)-INDANYL]-5-[(2(S)-TERTIARY BUTYLAMINOCARBONYL)-4(3-PYRIDYLMETHYL)PIPERAZINO]-4(S)-HYDROXY-2(R)-PHENYLMETHYLPENTANAMIDE
Authors:Chen, Z.
Deposit date:1995-03-31
Release date:1996-04-03
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure at 1.9-A resolution of human immunodeficiency virus (HIV) II protease complexed with L-735,524, an orally bioavailable inhibitor of the HIV proteases.
J.Biol.Chem., 269, 1994
4KF8
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BU of 4kf8 by Molmil
Nup188(aa1445-1827) from Myceliophthora thermophila
Descriptor: Nup188
Authors:Schwartz, T.U, Andersen, K.R.
Deposit date:2013-04-26
Release date:2013-06-19
Last modified:2013-08-14
Method:X-RAY DIFFRACTION (3 Å)
Cite:Scaffold nucleoporins Nup188 and Nup192 share structural and functional properties with nuclear transport receptors.
Elife, 2, 2013
4KF7
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BU of 4kf7 by Molmil
Nup188(aa1-1160) from Myceliophthora thermophila
Descriptor: Nup188
Authors:Schwartz, T.U, Andersen, K.R.
Deposit date:2013-04-26
Release date:2013-06-19
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Scaffold nucleoporins Nup188 and Nup192 share structural and functional properties with nuclear transport receptors.
Elife, 2, 2013
2BPV
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BU of 2bpv by Molmil
HIV-1 protease-inhibitor complex
Descriptor: 1-[2-HYDROXY-4-(2-HYDROXY-5-METHYL-CYCLOPENTYLCARBAMOYL)5-PHENYL-PENTYL]-4-(3-PYRIDIN-3-YL-PROPIONYL)-PIPERAZINE-2-CARB OXYLIC ACID TERT-BUTYLAMIDE, HIV-1 PROTEASE
Authors:Munshi, S, Chen, Z.
Deposit date:1998-01-22
Release date:1999-02-23
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Rapid X-ray diffraction analysis of HIV-1 protease-inhibitor complexes: inhibitor exchange in single crystals of the bound enzyme.
Acta Crystallogr.,Sect.D, 54, 1998
2BPY
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BU of 2bpy by Molmil
HIV-1 protease-inhibitor complex
Descriptor: HIV-1 PROTEASE, N-[2(S)-CYCLOPENTYL-1(R)-HYDROXY-3(R)METHYL]-5-[(2(S)-TERTIARY-BUTYLAMINO-CARBONYL)-4-(N1-(2)-(N-METHYLPIPERAZINYL)-3-CHLORO-PYRAZINYL-5-CARBONYL)-PIPERAZINO]-4(S)-HYDROXY-2(R)-PHENYLMETHYL-PENTANAMIDE
Authors:Munshi, S, Chen, Z.
Deposit date:1998-01-22
Release date:1999-02-23
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Rapid X-ray diffraction analysis of HIV-1 protease-inhibitor complexes: inhibitor exchange in single crystals of the bound enzyme.
Acta Crystallogr.,Sect.D, 54, 1998
2BPX
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BU of 2bpx by Molmil
HIV-1 protease-inhibitor complex
Descriptor: HIV-1 PROTEASE, N-[2(R)-HYDROXY-1(S)-INDANYL]-5-[(2(S)-TERTIARY BUTYLAMINOCARBONYL)-4(3-PYRIDYLMETHYL)PIPERAZINO]-4(S)-HYDROXY-2(R)-PHENYLMETHYLPENTANAMIDE
Authors:Munshi, S, Chen, Z.
Deposit date:1998-01-22
Release date:1999-02-23
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Rapid X-ray diffraction analysis of HIV-1 protease-inhibitor complexes: inhibitor exchange in single crystals of the bound enzyme.
Acta Crystallogr.,Sect.D, 54, 1998
2BPZ
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BU of 2bpz by Molmil
HIV-1 protease-inhibitor complex
Descriptor: HIV-1 PROTEASE, N-[2(S)-CYCLOPENTYL-1(R)-HYDROXY-3(R)METHYL]-5-[(2(S)-TERTIARY-BUTYLAMINO-CARBONYL)-4-(N1-(2)-(N-METHYLPIPERAZINYL)-3-CHLORO-PYRAZINYL-5-CARBONYL)-PIPERAZINO]-4(S)-HYDROXY-2(R)-PHENYLMETHYL-PENTANAMIDE
Authors:Munshi, S, Chen, Z.
Deposit date:1998-01-22
Release date:1999-02-23
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Rapid X-ray diffraction analysis of HIV-1 protease-inhibitor complexes: inhibitor exchange in single crystals of the bound enzyme.
Acta Crystallogr.,Sect.D, 54, 1998
2BPW
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BU of 2bpw by Molmil
HIV-1 protease-inhibitor complex
Descriptor: 1-[2-HYDROXY-4-(2-HYDROXY-5-METHYL-CYCLOPENTYLCARBAMOYL)5-PHENYL-PENTYL]-4-(3-PYRIDIN-3-YL-PROPIONYL)-PIPERAZINE-2-CARB OXYLIC ACID TERT-BUTYLAMIDE, HIV-1 PROTEASE
Authors:Munshi, S, Chen, Z.
Deposit date:1998-01-22
Release date:1999-02-23
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Rapid X-ray diffraction analysis of HIV-1 protease-inhibitor complexes: inhibitor exchange in single crystals of the bound enzyme.
Acta Crystallogr.,Sect.D, 54, 1998
1C6X
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BU of 1c6x by Molmil
ALTERNATE BINDING SITE FOR THE P1-P3 GROUP OF A CLASS OF POTENT HIV-1 PROTEASE INHIBITORS AS A RESULT OF CONCERTED STRUCTURAL CHANGE IN 80'S LOOP.
Descriptor: N-[2(S)-CYCLOPENTYL-1(R)-HYDROXY-3(R)METHYL]-5-[(2(S)-TERTIARY-BUTYLAMINO-CARBONYL)-4-(N1-(2)-(N-METHYLPIPERAZINYL)-3-CHLORO-PYRAZINYL-5-CARBONYL)-PIPERAZINO]-4(S)-HYDROXY-2(R)-PHENYLMETHYL-PENTANAMIDE, PROTEIN (PROTEASE)
Authors:Munshi, S.
Deposit date:1999-12-28
Release date:2000-12-28
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:An alternate binding site for the P1-P3 group of a class of potent HIV-1 protease inhibitors as a result of concerted structural change in the 80s loop of the protease.
Acta Crystallogr.,Sect.D, 56, 2000
1C6Y
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BU of 1c6y by Molmil
ALTERNATE BINDING SITE FOR THE P1-P3 GROUP OF A CLASS OF POTENT HIV-1 PROTEASE INHIBITORS AS A RESULT OF CONCERTED STRUCTURAL CHANGE IN 80'S LOOP.
Descriptor: N-[2(R)-HYDROXY-1(S)-INDANYL]-5-[(2(S)-TERTIARY BUTYLAMINOCARBONYL)-4(3-PYRIDYLMETHYL)PIPERAZINO]-4(S)-HYDROXY-2(R)-PHENYLMETHYLPENTANAMIDE, PROTEIN (PROTEASE)
Authors:Munshi, S.
Deposit date:1999-12-28
Release date:2000-12-28
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:An alternate binding site for the P1-P3 group of a class of potent HIV-1 protease inhibitors as a result of concerted structural change in the 80s loop of the protease.
Acta Crystallogr.,Sect.D, 56, 2000
6QT0
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BU of 6qt0 by Molmil
Cryo-EM structures of Lsg1-TAP pre-60S ribosomal particles
Descriptor: 25S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Kargas, V, Warren, A.J.
Deposit date:2019-02-22
Release date:2019-06-26
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Mechanism of completion of peptidyltransferase centre assembly in eukaryotes.
Elife, 8, 2019
6RZZ
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BU of 6rzz by Molmil
Cryo-EM structures of Lsg1-TAP pre-60S ribosomal particles
Descriptor: 25S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Kargas, V, Warren, A.J.
Deposit date:2019-06-13
Release date:2019-06-26
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Mechanism of completion of peptidyltransferase centre assembly in eukaryotes.
Elife, 8, 2019
6QTZ
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BU of 6qtz by Molmil
Cryo-EM structures of Lsg1-TAP pre-60S ribosomal particles
Descriptor: 25S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Kargas, V, Warren, A.J.
Deposit date:2019-02-26
Release date:2019-06-26
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Mechanism of completion of peptidyltransferase centre assembly in eukaryotes.
Elife, 8, 2019
6S05
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BU of 6s05 by Molmil
Cryo-EM structures of Lsg1-TAP pre-60S ribosomal particles
Descriptor: 25S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Kargas, V, Warren, A.J.
Deposit date:2019-06-13
Release date:2019-06-26
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Mechanism of completion of peptidyltransferase centre assembly in eukaryotes.
Elife, 8, 2019
6RI5
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BU of 6ri5 by Molmil
Cryo-EM structures of Lsg1-TAP pre-60S ribosomal particles
Descriptor: 25S RNA, 5.8S rRNA, 5S rRNA, ...
Authors:Kargas, V, Warren, A.J.
Deposit date:2019-04-23
Release date:2019-06-26
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Mechanism of completion of peptidyltransferase centre assembly in eukaryotes.
Elife, 8, 2019
6OSW
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BU of 6osw by Molmil
An order-to-disorder structural switch activates the FoxM1 transcription factor
Descriptor: Forkhead box M1
Authors:Marceau, A.H, Rubin, S.M, Nerli, S, McShane, A.C, Sgourakis, N.G.
Deposit date:2019-05-02
Release date:2019-05-29
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:An order-to-disorder structural switch activates the FoxM1 transcription factor.
Elife, 8, 2019
6QIK
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BU of 6qik by Molmil
Cryo-EM structures of Lsg1-TAP pre-60S ribosomal particles
Descriptor: 25S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Kargas, V, Warren, A.J.
Deposit date:2019-01-20
Release date:2019-06-26
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Mechanism of completion of peptidyltransferase centre assembly in eukaryotes.
Elife, 8, 2019

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