2BN5
 
 | | P-Element Somatic Inhibitor Protein Complex with U1-70k proline-rich peptide | | Descriptor: | PSI, U1 SMALL NUCLEAR RIBONUCLEOPROTEIN 70 KDA | | Authors: | Ignjatovic, T, Yang, J.-C, Butler, P.J.G, Neuhaus, D, Nagai, K. | | Deposit date: | 2005-03-21 | | Release date: | 2005-07-06 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Structural Basis of the Interaction between P-Element Somatic Inhibitor and U1-70K Essential for the Alternative Splicing of P-Element Transposase.
J.Mol.Biol., 351, 2005
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2BO5
 | | Bovine oligomycin sensitivity conferral protein N-terminal domain | | Descriptor: | ATP SYNTHASE OLIGOMYCIN SENSITIVITY CONFERRAL PROTEIN | | Authors: | Carbajo, R.J, Kellas, F.A, Runswick, M.J, Montgomery, M.G, Walker, J.E, Neuhaus, D. | | Deposit date: | 2005-04-07 | | Release date: | 2005-08-17 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Structure of the F1-binding domain of the stator of bovine F1Fo-ATPase and how it binds an alpha-subunit.
J. Mol. Biol., 351, 2005
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1XC5
 | | Solution Structure of the SMRT Deacetylase Activation Domain | | Descriptor: | Nuclear receptor corepressor 2 | | Authors: | Codina, A, Love, J.D, Li, Y, Lazar, M.A, Neuhaus, D, Schwabe, J.W.R. | | Deposit date: | 2004-09-01 | | Release date: | 2005-05-03 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Structural insights into the interaction and activation of histone deacetylase 3 by nuclear receptor corepressors
Proc.Natl.Acad.Sci.Usa, 102, 2005
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1VZS
 | | Solution structure of subunit F6 from the peripheral stalk region of ATP synthase from bovine heart mitochondria | | Descriptor: | ATP SYNTHASE COUPLING FACTOR 6, MITOCHONDRIAL PRECURSOR | | Authors: | Carbajo, R.J, Silvester, J.A, Runswick, M.J, Walker, J.E, Neuhaus, D. | | Deposit date: | 2004-05-25 | | Release date: | 2004-09-02 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Solution Structure of Subunit F(6) from the Peripheral Stalk Region of ATP Synthase from Bovine Heart Mitochondria
J.Mol.Biol., 342, 2004
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2VRD
 | | THE STRUCTURE OF THE ZINC FINGER FROM THE HUMAN SPLICEOSOMAL PROTEIN U1C | | Descriptor: | U1 SMALL NUCLEAR RIBONUCLEOPROTEIN C, ZINC ION | | Authors: | Muto, Y, Pomeranz-Krummel, D, Oubridge, C, Hernandez, H, Robinson, C, Neuhaus, D, Nagai, K. | | Deposit date: | 2008-03-31 | | Release date: | 2008-04-08 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | The Structure and Biochemical Properties of the Human Spliceosomal Protein U1C
J.Mol.Biol., 341, 2004
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7AAD
 | | Crystal structure of the catalytic domain of human PARP1 in complex with olaparib | | Descriptor: | 4-(3-{[4-(cyclopropylcarbonyl)piperazin-1-yl]carbonyl}-4-fluorobenzyl)phthalazin-1(2H)-one, Poly [ADP-ribose] polymerase 1, SULFATE ION | | Authors: | Schimpl, M, Ogden, T.E.H, Yang, J.-C, Easton, L.E, Underwood, E, Rawlins, P.B, Johannes, J.W, Embrey, K.J, Neuhaus, D. | | Deposit date: | 2020-09-04 | | Release date: | 2021-01-13 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (2.21 Å) | | Cite: | Dynamics of the HD regulatory subdomain of PARP-1; substrate access and allostery in PARP activation and inhibition.
Nucleic Acids Res., 49, 2021
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7AAA
 | | Crystal structure of the catalytic domain of human PARP1 (apo) | | Descriptor: | 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, Poly [ADP-ribose] polymerase 1, ... | | Authors: | Schimpl, M, Ogden, T.E.H, Yang, J.-C, Underwood, E, Rawlins, P.B, Johannes, J.W, Easton, L.E, Embrey, K.J, Neuhaus, D. | | Deposit date: | 2020-09-04 | | Release date: | 2021-01-13 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (1.74 Å) | | Cite: | Dynamics of the HD regulatory subdomain of PARP-1; substrate access and allostery in PARP activation and inhibition.
Nucleic Acids Res., 49, 2021
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7AAC
 | | Crystal structure of the catalytic domain of human PARP1 in complex with veliparib | | Descriptor: | (2R)-2-(7-carbamoyl-1H-benzimidazol-2-yl)-2-methylpyrrolidinium, Poly [ADP-ribose] polymerase 1, SULFATE ION | | Authors: | Schimpl, M, Ogden, T.E.H, Yang, J.-C, Easton, L.E, Underwood, E, Rawlins, P.B, Johannes, J.W, Embrey, K.J, Neuhaus, D. | | Deposit date: | 2020-09-04 | | Release date: | 2021-01-13 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (1.593 Å) | | Cite: | Dynamics of the HD regulatory subdomain of PARP-1; substrate access and allostery in PARP activation and inhibition.
Nucleic Acids Res., 49, 2021
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7AAB
 | | Crystal structure of the catalytic domain of human PARP1 in complex with inhibitor EB-47 | | Descriptor: | 2-[4-[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]carbonylpiperazin-1-yl]-N-(1-oxidanylidene-2,3-dihydroisoindol-4-yl)ethanamide, Poly [ADP-ribose] polymerase 1, SULFATE ION | | Authors: | Schimpl, M, Ogden, T.E.H, Yang, J.-C, Easton, L.E, Underwood, E, Rawlins, P.B, Johannes, J.W, Embrey, K.J, Neuhaus, D. | | Deposit date: | 2020-09-04 | | Release date: | 2021-01-13 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Dynamics of the HD regulatory subdomain of PARP-1; substrate access and allostery in PARP activation and inhibition.
Nucleic Acids Res., 49, 2021
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6RH6
 | | Solution structure and 1H, 13C and 15N chemical shift assignments for the complex of NECAP1 PHear domain with phosphorylated AP2 mu2 148-163 | | Descriptor: | AP-2 complex subunit mu, Adaptin ear-binding coat-associated protein 1 | | Authors: | Owen, D.J, Neuhaus, D, Yang, J.-C, Herrmann, T. | | Deposit date: | 2019-04-18 | | Release date: | 2019-09-04 | | Last modified: | 2024-11-13 | | Method: | SOLUTION NMR | | Cite: | Temporal Ordering in Endocytic Clathrin-Coated Vesicle Formation via AP2 Phosphorylation.
Dev.Cell, 50, 2019
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6S53
 | | Crystal structure of TRIM21 RING domain in complex with an isopeptide-linked Ube2N~ubiquitin conjugate | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, E3 ubiquitin-protein ligase TRIM21, Polyubiquitin-C, ... | | Authors: | Kiss, L, Boland, A, Neuhaus, D, James, L.C. | | Deposit date: | 2019-06-30 | | Release date: | 2019-09-11 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | A tri-ionic anchor mechanism drives Ube2N-specific recruitment and K63-chain ubiquitination in TRIM ligases.
Nat Commun, 10, 2019
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6RH5
 | | Solution structure and 1H, 13C and 15N chemical shift assignments for NECAP1 PHear domain | | Descriptor: | Adaptin ear-binding coat-associated protein 1 | | Authors: | Owen, D.J, Neuhaus, D, Yang, J.-C, Herrmann, T. | | Deposit date: | 2019-04-18 | | Release date: | 2019-09-04 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Temporal Ordering in Endocytic Clathrin-Coated Vesicle Formation via AP2 Phosphorylation.
Dev.Cell, 50, 2019
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8R1X
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1GO5
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1HMA
 | | THE SOLUTION STRUCTURE AND DYNAMICS OF THE DNA BINDING DOMAIN OF HMG-D FROM DROSOPHILA MELANOGASTER | | Descriptor: | HMG-D | | Authors: | Jones, D.N.M, Searles, M.A, Shaw, G.L, Churchill, M.E.A, Ner, S.S, Keeler, J, Travers, A.A, Neuhaus, D. | | Deposit date: | 1994-05-12 | | Release date: | 1994-07-31 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | The solution structure and dynamics of the DNA-binding domain of HMG-D from Drosophila melanogaster.
Structure, 2, 1994
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1HF9
 | | C-Terminal Coiled-Coil Domain from Bovine IF1 | | Descriptor: | ATPASE INHIBITOR (MITOCHONDRIAL) | | Authors: | Gordon-Smith, D.J, Carbajo, R.J, Yang, J.-C, Videler, H, Runswick, M.J, Walker, J.E, Neuhaus, D. | | Deposit date: | 2000-11-30 | | Release date: | 2001-05-31 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Solution structure of a C-terminal coiled-coil domain from bovine IF(1): the inhibitor protein of F(1) ATPase.
J. Mol. Biol., 308, 2001
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1DZ5
 | | The NMR structure of the 38KDa U1A protein-PIE RNA complex reveals the basis of cooperativity in regulation of polyadenylation by human U1A protein | | Descriptor: | PIE, RNA (5'-R(*GP*AP*GP*AP*CP*AP*UP*UP*GP*CP*AP*CP*CP* CP*GP*GP*AP*GP*UP*CP*UP*C)-3'), U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A | | Authors: | Varani, L, Gunderson, S.I, Mattaj, I.W, Kay, L.E, Neuhaus, D, Varani, G. | | Deposit date: | 2000-02-16 | | Release date: | 2000-03-29 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | The NMR Structure of the 38kDa U1A Protein-Pie RNA Complex Reveals the Basis of Cooperativity in Regulation of Polyadenylation by Human U1A Protein
Nat.Struct.Biol., 7, 2000
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1FHT
 | | RNA-BINDING DOMAIN OF THE U1A SPLICEOSOMAL PROTEIN U1A117, NMR, 43 STRUCTURES | | Descriptor: | U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A | | Authors: | Allain, F.H.-T, Gubser, C.C, Howe, P.W.A, Nagai, K, Neuhaus, D, Varani, G. | | Deposit date: | 1996-02-21 | | Release date: | 1996-07-11 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the N-terminal RNP domain of U1A protein: the role of C-terminal residues in structure stability and RNA binding.
J.Mol.Biol., 257, 1996
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2LBM
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2JM1
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2MY1
 | | Solution structure of Bud31p | | Descriptor: | Pre-mRNA-splicing factor BUD31, ZINC ION | | Authors: | van Roon, A.M, Yang, J, Mathieu, D, Bermel, W, Nagai, K, Neuhaus, D. | | Deposit date: | 2015-01-19 | | Release date: | 2015-03-11 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | (113) Cd NMR Experiments Reveal an Unusual Metal Cluster in the Solution Structure of the Yeast Splicing Protein Bud31p.
Angew.Chem.Int.Ed.Engl., 54, 2015
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2KHH
 | | Structural requirements for the UBA domain of the mRNA export factor Mex67 to bind its specific targets, the transcription elongation Tho complex component Hpr1 and nucleoporin FxFG repeats | | Descriptor: | FxFG, mRNA export factor MEX67 | | Authors: | Hobeika, M, Brockmann, C, Gruessing, F, Neuhaus, D, Divita, G, Stewart, M, Dargemont, C. | | Deposit date: | 2009-04-06 | | Release date: | 2009-05-12 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Structural requirements for the ubiquitin-associated domain of the mRNA export factor Mex67 to bind its specific targets, the transcription elongation THO complex component Hpr1 and nucleoporin FXFG repeats
J.Biol.Chem., 284, 2009
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2K0A
 | | 1H, 15N and 13C chemical shift assignments for Rds3 protein | | Descriptor: | Pre-mRNA-splicing factor RDS3, ZINC ION | | Authors: | Loening, N, van Roon, A, Yang, J, Nagai, K, Neuhaus, D. | | Deposit date: | 2008-01-31 | | Release date: | 2008-07-22 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the U2 snRNP protein Rds3p reveals a knotted zinc-finger motif.
Proc.Natl.Acad.Sci.Usa, 105, 2008
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2JMX
 | | OSCP-NT (1-120) in complex with N-terminal (1-25) alpha subunit from F1-ATPase | | Descriptor: | ATP synthase O subunit, mitochondrial, ATP synthase subunit alpha heart isoform | | Authors: | Carbajo, R.J, Neuhaus, D, Kellas, F.A, Yang, J, Runswick, M.J, Montgomery, M.G, Walker, J.E. | | Deposit date: | 2006-12-12 | | Release date: | 2007-04-24 | | Last modified: | 2023-12-20 | | Method: | SOLUTION NMR | | Cite: | How the N-terminal Domain of the OSCP Subunit of Bovine F(1)F(o)-ATP Synthase Interacts with the N-terminal Region of an Alpha Subunit
J.Mol.Biol., 368, 2007
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2JP7
 | | NMR structure of the Mex67 UBA domain | | Descriptor: | mRNA export factor MEX67 | | Authors: | Hobeika, M, Brockmann, C, Iglesias, N, Gwizdek, C, Neuhaus, D, Stutz, F, Stewart, M, Divita, G, Dargemont, C. | | Deposit date: | 2007-04-26 | | Release date: | 2007-07-10 | | Last modified: | 2023-12-20 | | Method: | SOLUTION NMR | | Cite: | Coordination of Hpr1 and ubiquitin binding by the UBA domain of the mRNA export factor Mex67
Mol.Cell.Biol., 18, 2007
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