3F8T
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7WCM
| Cryo-EM structure of GPR119-Gs Complex with small molecule agonist MBX-2982 | Descriptor: | 2-[1-(5-ethylpyrimidin-2-yl)piperidin-4-yl]-4-[[4-(1,2,3,4-tetrazol-1-yl)phenoxy]methyl]-1,3-thiazole, Glucose-dependent insulinotropic receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Qiao, A.N, Wu, S, Ye, S. | Deposit date: | 2021-12-20 | Release date: | 2022-12-21 | Last modified: | 2022-12-28 | Method: | ELECTRON MICROSCOPY (2.33 Å) | Cite: | Activation and signaling mechanism revealed by GPR119-G s complex structures. Nat Commun, 13, 2022
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7WCN
| Cryo-EM structure of GPR119-Gs Complex with small molecule agonist AR231453 | Descriptor: | Glucose-dependent insulinotropic receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Qiao, A.N, Wu, S, Ye, S. | Deposit date: | 2021-12-20 | Release date: | 2022-12-21 | Last modified: | 2022-12-28 | Method: | ELECTRON MICROSCOPY (2.87 Å) | Cite: | Activation and signaling mechanism revealed by GPR119-G s complex structures. Nat Commun, 13, 2022
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2MJV
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2DHO
| Crystal structure of human IPP isomerase I in space group P212121 | Descriptor: | CHLORIDE ION, Isopentenyl-diphosphate delta-isomerase 1, MANGANESE (II) ION, ... | Authors: | Zhang, C, Wei, Z, Gong, W. | Deposit date: | 2006-03-24 | Release date: | 2007-06-05 | Last modified: | 2021-11-10 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal structures of human IPP isomerase: new insights into the catalytic mechanism J.Mol.Biol., 366, 2007
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2JZY
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7ES2
| a mutant of glycosyktransferase in complex with UDP and Reb D | Descriptor: | Glycosyltransferase, URIDINE-5'-DIPHOSPHATE, rebaudioside D | Authors: | Zhu, X. | Deposit date: | 2021-05-08 | Release date: | 2021-12-08 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.34 Å) | Cite: | Catalytic flexibility of rice glycosyltransferase OsUGT91C1 for the production of palatable steviol glycosides. Nat Commun, 12, 2021
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7ERX
| Glycosyltransferase in complex with UDP and STB | Descriptor: | GLYCEROL, Glycosyltransferase, Steviolbioside, ... | Authors: | Zhu, X. | Deposit date: | 2021-05-08 | Release date: | 2021-12-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | Catalytic flexibility of rice glycosyltransferase OsUGT91C1 for the production of palatable steviol glycosides. Nat Commun, 12, 2021
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7ES1
| glycosyltransferase in complex with UDP and ST | Descriptor: | Glycosyltransferase, URIDINE-5'-DIPHOSPHATE, steviol-19-o-glucoside | Authors: | Zhu, X. | Deposit date: | 2021-05-08 | Release date: | 2021-12-08 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.66 Å) | Cite: | Catalytic flexibility of rice glycosyltransferase OsUGT91C1 for the production of palatable steviol glycosides. Nat Commun, 12, 2021
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7ES0
| a rice glycosyltransferase in complex with UDP and REX | Descriptor: | 1,2-ETHANEDIOL, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, GLYCEROL, ... | Authors: | Zhu, X. | Deposit date: | 2021-05-08 | Release date: | 2021-12-08 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.395 Å) | Cite: | Catalytic flexibility of rice glycosyltransferase OsUGT91C1 for the production of palatable steviol glycosides. Nat Commun, 12, 2021
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7ERY
| apo form of the glycosyltransferase | Descriptor: | Glycosyltransferase | Authors: | Zhu, X. | Deposit date: | 2021-05-08 | Release date: | 2021-12-08 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Catalytic flexibility of rice glycosyltransferase OsUGT91C1 for the production of palatable steviol glycosides. Nat Commun, 12, 2021
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2F90
| Crystal structure of bisphosphoglycerate mutase in complex with 3-phosphoglycerate and AlF4- | Descriptor: | 3-PHOSPHOGLYCERIC ACID, Bisphosphoglycerate mutase, TETRAFLUOROALUMINATE ION | Authors: | Wang, Y, Liu, L, Wei, Z, Gong, W. | Deposit date: | 2005-12-05 | Release date: | 2006-10-24 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Seeing the process of histidine phosphorylation in human bisphosphoglycerate mutase J.Biol.Chem., 281, 2006
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7V52
| Structure of AdaV | Descriptor: | AdaV, FE (III) ION | Authors: | Zhang, Z.Y, Chen, W.Q, Zhai, G.Q, Zhang, M. | Deposit date: | 2021-08-16 | Release date: | 2022-08-24 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.38 Å) | Cite: | Structural Insight into the Catalytic Mechanism of Non-Heme Iron Halogenase AdaV in 2'-Chloropentostatin Biosynthesis Acs Catalysis, 12, 2022
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7V57
| Structure of AdaV | Descriptor: | 2-OXOGLUTARIC ACID, AdaV, CHLORIDE ION, ... | Authors: | Zhang, Z.Y, Chen, W.Q, Zhai, G.Q, Zhang, M. | Deposit date: | 2021-08-16 | Release date: | 2022-08-24 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structural Insight into the Catalytic Mechanism of Non-Heme Iron Halogenase AdaV in 2'-Chloropentostatin Biosynthesis Acs Catalysis, 12, 2022
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7V54
| Structure of AdaV | Descriptor: | AdaV, FE (III) ION | Authors: | Zhang, Z.Y, Chen, W.Q, Zhai, G.Q, Zhang, M. | Deposit date: | 2021-08-16 | Release date: | 2022-08-24 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.12 Å) | Cite: | Structural Insight into the Catalytic Mechanism of Non-Heme Iron Halogenase AdaV in 2'-Chloropentostatin Biosynthesis Acs Catalysis, 12, 2022
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7V56
| Structure of AdaV | Descriptor: | AdaV, FE (III) ION | Authors: | Zhang, Z.Y, Chen, W.Q, Zhai, G.Q, Zhang, M. | Deposit date: | 2021-08-16 | Release date: | 2022-08-24 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.27 Å) | Cite: | Structural Insight into the Catalytic Mechanism of Non-Heme Iron Halogenase AdaV in 2'-Chloropentostatin Biosynthesis Acs Catalysis, 12, 2022
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7V7X
| Structure of H194A AdaV | Descriptor: | 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE, AdaV | Authors: | Zhang, Z.Y, Chen, W.Q, Zhai, G.Q, Zhang, M. | Deposit date: | 2021-08-22 | Release date: | 2022-08-31 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural Insight into the Catalytic Mechanism of Non-Heme Iron Halogenase AdaV in 2'-Chloropentostatin Biosynthesis Acs Catalysis, 12, 2022
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7EOD
| MITF HLHLZ Delta AKE | Descriptor: | GLYCEROL, Isoform M1 of Microphthalmia-associated transcription factor | Authors: | Li, P, Liu, Z, Fang, P, Wang, J. | Deposit date: | 2021-04-22 | Release date: | 2022-04-27 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | A unique hyperdynamic dimer interface permits small molecule perturbation of the melanoma oncoprotein MITF for melanoma therapy. Cell Res., 33, 2023
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7D8T
| MITF bHLHLZ complex with M-box DNA | Descriptor: | DNA (5'-D(*TP*GP*TP*AP*AP*CP*AP*TP*GP*TP*GP*TP*CP*CP*CP*C)-3'), DNA (5'-D(P*GP*GP*GP*AP*CP*AP*CP*AP*TP*GP*TP*TP*AP*CP*AP*G)-3'), Microphthalmia-associated transcription factor,Methionyl-tRNA synthetase beta subunit | Authors: | Guo, M, Fang, P, Wang, J. | Deposit date: | 2020-10-09 | Release date: | 2021-10-13 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (3.201 Å) | Cite: | A unique hyperdynamic dimer interface permits small molecule perturbation of the melanoma oncoprotein MITF for melanoma therapy. Cell Res., 33, 2023
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7D8R
| MITF HLHLZ structure | Descriptor: | Microphthalmia-associated transcription factor,Methionyl-tRNA synthetase beta subunit | Authors: | Guo, M, Fang, P, Wang, J. | Deposit date: | 2020-10-09 | Release date: | 2021-10-13 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | A unique hyperdynamic dimer interface permits small molecule perturbation of the melanoma oncoprotein MITF for melanoma therapy. Cell Res., 33, 2023
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7D8S
| MITF bHLHLZ apo structure | Descriptor: | Microphthalmia-associated transcription factor,Methionyl-tRNA synthetase beta subunit, SULFATE ION | Authors: | Guo, M, Fang, P, Wang, J. | Deposit date: | 2020-10-09 | Release date: | 2021-10-13 | Last modified: | 2024-10-23 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | A unique hyperdynamic dimer interface permits small molecule perturbation of the melanoma oncoprotein MITF for melanoma therapy. Cell Res., 33, 2023
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7FIX
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4FLN
| Crystal structure of plant protease Deg2 | Descriptor: | Protease Do-like 2, chloroplastic, Unknown peptide | Authors: | Gong, W, Liu, L, Sun, R, Gao, F. | Deposit date: | 2012-06-15 | Release date: | 2012-09-19 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of Arabidopsis deg2 protein reveals an internal PDZ ligand locking the hexameric resting state. J.Biol.Chem., 287, 2012
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7FH5
| Structure of AdaV | Descriptor: | AdaV, CHLORIDE ION, FE (III) ION | Authors: | Zhang, Z.Y, Chen, W.Q, Zhai, G.Q, Zhang, M. | Deposit date: | 2021-07-29 | Release date: | 2022-08-03 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural Insight into the Catalytic Mechanism of Non-Heme Iron Halogenase AdaV in 2'-Chloropentostatin Biosynthesis Acs Catalysis, 12, 2022
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2WLU
| Iron-bound crystal structure of Streptococcus pyogenes Dpr | Descriptor: | DPS-LIKE PEROXIDE RESISTANCE PROTEIN, FE (III) ION, GLYCEROL, ... | Authors: | Haikarainen, T, Tsou, C.-C, Wu, J.-J, Papageorgiou, A.C. | Deposit date: | 2009-06-26 | Release date: | 2009-09-15 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Crystal Structures of Streptococcus Pyogenes Dpr Reveal a Dodecameric Iron-Binding Protein with a Ferroxidase Site. J.Biol.Inorg.Chem., 15, 2010
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