6HYO
 
 | | Structure of ULK1 LIR motif bound to GABARAP | | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | | Authors: | Mouilleron, S, Wirth, M, Zhang, W, O'Reilly, N, Tooze, S, Johansen, T, Razi, M, Nyoni, L, Joshi, D. | | Deposit date: | 2018-10-22 | | Release date: | 2019-05-08 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.07 Å) | | Cite: | Molecular determinants regulating selective binding of autophagy adapters and receptors to ATG8 proteins.
Nat Commun, 10, 2019
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5HTR
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5HUX
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5HTY
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8XLZ
 | | beta-1,4-galacosyltransferase | | Descriptor: | Glycosyltransferase family 25 protein, MAGNESIUM ION, URIDINE-5'-DIPHOSPHATE | | Authors: | Luo, G, Huang, Z, Chen, J, Hou, X, Zhu, Y, Ni, D, Xu, W, Zhang, W, Rao, Y, Mu, W. | | Deposit date: | 2023-12-26 | | Release date: | 2024-12-11 | | Method: | X-RAY DIFFRACTION (1.84 Å) | | Cite: | Crystal structure and structure-guided tunnel engineering in a bacterial beta-1,4-galactosyltransferase.
Int.J.Biol.Macromol., 279, 2024
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8XKD
 | | beta-1,4-galacosyltransferase | | Descriptor: | DI(HYDROXYETHYL)ETHER, Glycosyltransferase family 25 protein, TRIETHYLENE GLYCOL, ... | | Authors: | Luo, G, Huang, Z, Chen, J, Hou, X, Zhu, Y, Ni, D, Xu, W, Zhang, W, Rao, Y, Mu, W. | | Deposit date: | 2023-12-23 | | Release date: | 2024-12-11 | | Method: | X-RAY DIFFRACTION (1.73 Å) | | Cite: | Crystal structure and structure-guided tunnel engineering in a bacterial beta-1,4-galactosyltransferase.
Int.J.Biol.Macromol., 279, 2024
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8XOC
 | | beta-1,4-galacosyltransferase | | Descriptor: | GALACTOSE-URIDINE-5'-DIPHOSPHATE, Glycosyltransferase family 25 protein, MAGNESIUM ION | | Authors: | Luo, G, Huang, Z, Chen, J, Hou, X, Zhu, Y, Ni, D, Xu, W, Zhang, W, Rao, Y, Mu, W. | | Deposit date: | 2023-12-31 | | Release date: | 2024-12-11 | | Method: | X-RAY DIFFRACTION (1.87 Å) | | Cite: | Crystal structure and structure-guided tunnel engineering in a bacterial beta-1,4-galactosyltransferase.
Int.J.Biol.Macromol., 279, 2024
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8XGX
 | | beta-1,4-galacosyltransferase | | Descriptor: | Glycosyltransferase family 25 protein | | Authors: | Luo, G, Huang, Z, Chen, J, Hou, X, Zhu, Y, Ni, D, Xu, W, Zhang, W, Rao, Y, Mu, W. | | Deposit date: | 2023-12-15 | | Release date: | 2024-12-11 | | Method: | X-RAY DIFFRACTION (2.41 Å) | | Cite: | Crystal structure and structure-guided tunnel engineering in a bacterial beta-1,4-galactosyltransferase.
Int.J.Biol.Macromol., 279, 2024
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6HOH
 | | Structure of VPS34 LIR motif (S249E) bound to GABARAP | | Descriptor: | Phosphatidylinositol 3-kinase catalytic subunit type 3,Gamma-aminobutyric acid receptor-associated protein, TRIETHYLENE GLYCOL | | Authors: | Mouilleron, S, Birgisdottir, A.B, Bhujbal, Z, Wirth, M, Sjottem, E, Evjen, G, Zhang, W, Lee, R, O'Reilly, N, Tooze, S, Lamark, T, Johansen, T. | | Deposit date: | 2018-09-17 | | Release date: | 2019-02-27 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Members of the autophagy class III phosphatidylinositol 3-kinase complex I interact with GABARAP and GABARAPL1 via LIR motifs.
Autophagy, 15, 2019
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6HOI
 | | Structure of Beclin1 LIR motif bound to GABARAPL1 | | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, Beclin-1, ... | | Authors: | Mouilleron, S, Birgisdottir, A.B, Bhujbal, Z, Wirth, M, Sjottem, E, Evjen, G, Zhang, W, Lee, R, O'Reilly, N, Tooze, S, Lamark, T, Johansen, T. | | Deposit date: | 2018-09-17 | | Release date: | 2019-02-27 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.14 Å) | | Cite: | Members of the autophagy class III phosphatidylinositol 3-kinase complex I interact with GABARAP and GABARAPL1 via LIR motifs.
Autophagy, 15, 2019
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1K4R
 | | Structure of Dengue Virus | | Descriptor: | MAJOR ENVELOPE PROTEIN E | | Authors: | Kuhn, R.J, Zhang, W, Rossmann, M.G, Pletnev, S.V, Corver, J, Lenches, E, Jones, C.T, Mukhopadhyay, S, Chipman, P.R, Strauss, E.G, Baker, T.S, Strauss, J.H. | | Deposit date: | 2001-10-08 | | Release date: | 2002-03-13 | | Last modified: | 2024-10-30 | | Method: | ELECTRON MICROSCOPY (24 Å) | | Cite: | Structure of dengue virus: implications for flavivirus organization, maturation, and fusion.
Cell(Cambridge,Mass.), 108, 2002
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8F2O
 | | Phi-29 expanded, DNA-packaged fiberless prohead | | Descriptor: | Major capsid protein | | Authors: | Woodson, M.E, Morais, M.C, Jardine, P.J, Zhang, W. | | Deposit date: | 2022-11-08 | | Release date: | 2023-11-15 | | Last modified: | 2025-05-28 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Phi29 assembly intermediates reveal how scaffold interactions with capsid protein drive capsid construction and maturation
Sci Adv, 11, 2025
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8F2N
 | | Phi-29 partially-expanded fiberless prohead | | Descriptor: | Major capsid protein | | Authors: | Woodson, M.E, Morais, M.C, Scott, S.D, Choi, K.H, Jardine, P.J, Zhang, W. | | Deposit date: | 2022-11-08 | | Release date: | 2023-11-15 | | Last modified: | 2025-05-28 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Phi29 assembly intermediates reveal how scaffold interactions with capsid protein drive capsid construction and maturation
Sci Adv, 11, 2025
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8X3K
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8J7C
 | | Crystal structure of triosephosphate isomerase from Leishmania orientalis at 1.88A with an arsenic ion bound at Cys57 | | Descriptor: | ARSENIC, Triosephosphate isomerase | | Authors: | Kuaprasert, B, Attarataya, J, Riangrungroj, P, Pornthanakasem, W, Suginta, W, Mungthin, M, Leelayoova, S, Choowongkomon, K, Leartsakulpanich, U. | | Deposit date: | 2023-04-27 | | Release date: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (1.88 Å) | | Cite: | Leishmania orientalis triosephosphate isomerase crystal structure at 1.45 angstroms resolution and its potential specific inhibitors
To be published
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2L85
 | | Solution NMR structures of CBP bromodomain with small molecule of HBS | | Descriptor: | 4-[(E)-(4-hydroxyphenyl)diazenyl]benzenesulfonic acid, CREB-binding protein | | Authors: | Borah, J.C, Mujtaba, S, Karakikes, I, Zeng, L, Muller, M, Patel, J, Moshkina, N, Morohashi, K, Zhang, W, Gerona-Navarro, G, Hajjar, R.J, Zhou, M. | | Deposit date: | 2011-01-04 | | Release date: | 2011-01-19 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | A Small Molecule Binding to the Coactivator CREB-Binding Protein Blocks Apoptosis in Cardiomyocytes.
Chem.Biol., 18, 2011
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8JBP
 | | Crystal structure of triosephosphate isomerase from Leishmania orientalis at 1.45 angstroms resolution with an arsenic atom bound at Cys57 | | Descriptor: | ARSENIC, Triosephosphate isomerase | | Authors: | Kuaprasert, B, Leartsakulpanich, U, Riangrungroj, P, Pornthanakasem, W, Suginta, W, Robinson, R.C, Zhou, Y, Mungthin, M, Leelayoova, S, Saehlee, S, Choowongkomon, K. | | Deposit date: | 2023-05-09 | | Release date: | 2024-05-15 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | Leishmania orientalis triosephosphate isomerase crystal structure at 1.45 angstroms resolution and its potential specific inhibitors
To be published
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6AEJ
 | | Crystal structure of human FTO in complex with small-molecule inhibitors | | Descriptor: | (E)-3-[3-nitro-4,5-bis(oxidanyl)phenyl]-2-(1,3-oxazinan-3-ylcarbonyl)prop-2-enenitrile, Alpha-ketoglutarate-dependent dioxygenase FTO,Alpha-ketoglutarate-dependent dioxygenase FTO, ZINC ION | | Authors: | Wang, Y, Cao, R, Peng, S, Zhang, W, Huang, N. | | Deposit date: | 2018-08-05 | | Release date: | 2019-06-19 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Identification of entacapone as a chemical inhibitor of FTO mediating metabolic regulation through FOXO1.
Sci Transl Med, 11, 2019
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2JZ0
 | | DSX_short | | Descriptor: | Protein doublesex | | Authors: | Yang, Y, Zhang, W, Bayrer, J.R, Weiss, M.A. | | Deposit date: | 2007-12-21 | | Release date: | 2008-01-08 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Doublesex and the Regulation of Sexual Dimorphism in Drosophila melanogaster: STRUCTURE, FUNCTION, AND MUTAGENESIS OF A FEMALE-SPECIFIC DOMAIN.
J.Biol.Chem., 283, 2008
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8IQ6
 | | Cryo-EM structure of Latanoprost-bound prostaglandin-F2-alpha receptor-miniGq-Nb35 complex | | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | | Authors: | Lv, X, Gao, K, Nie, J, Zhang, X, Zhang, S, Ren, Y, Li, Q, Huang, J, Liu, L, Zhang, X, Sun, X, Zhang, W, Liu, X. | | Deposit date: | 2023-03-15 | | Release date: | 2024-01-31 | | Last modified: | 2024-11-06 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structures of human prostaglandin F 2 alpha receptor reveal the mechanism of ligand and G protein selectivity.
Nat Commun, 14, 2023
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8IQ4
 | | Cryo-EM structure of Carboprost-bound prostaglandin-F2-alpha receptor-miniGq-Nb35 complex | | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | | Authors: | Lv, X, Gao, K, Nie, J, Zhang, X, Zhang, S, Ren, Y, Li, Q, Huang, J, Liu, L, Zhang, X, Sun, X, Zhang, W, Liu, X. | | Deposit date: | 2023-03-15 | | Release date: | 2024-01-31 | | Last modified: | 2024-10-16 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Structures of human prostaglandin F 2 alpha receptor reveal the mechanism of ligand and G protein selectivity.
Nat Commun, 14, 2023
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5MDN
 | | Structure of the family B DNA polymerase from the hyperthermophilic archaeon Pyrobaculum calidifontis | | Descriptor: | DNA polymerase, MAGNESIUM ION | | Authors: | Guo, J, Zhang, W, Coker, A.R, Wood, S.P, Cooper, J.B, Rashid, N, Akhtar, M. | | Deposit date: | 2016-11-12 | | Release date: | 2016-12-14 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structure of the family B DNA polymerase from the hyperthermophilic archaeon Pyrobaculum calidifontis.
Acta Crystallogr D Struct Biol, 73, 2017
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3AQQ
 | | Crystal structure of human CRHSP-24 | | Descriptor: | Calcium-regulated heat stable protein 1 | | Authors: | Hou, H, Wang, F, Zhang, W, Wang, D, Li, X, Bartlam, M, Yao, X, Rao, Z. | | Deposit date: | 2010-11-17 | | Release date: | 2010-12-22 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.798 Å) | | Cite: | CRHSP-24 is a novel cargo adaptor trafficking between stress granules and processing bodies
To be Published
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7DW5
 | | Crystal structure of DUX4 HD1-HD2 domain complexed with ERG sites | | Descriptor: | BROMIDE ION, DNA (5'-D(P*CP*GP*AP*CP*TP*TP*GP*AP*TP*GP*AP*GP*AP*TP*TP*AP*GP*AP*CP*TP*G)-3'), Double homeobox protein 4-like protein 2 | | Authors: | Zhang, H, Cheng, N, Li, Z, Zhang, W, Dong, X, Huang, J, Meng, G. | | Deposit date: | 2021-01-15 | | Release date: | 2021-11-03 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.83 Å) | | Cite: | DNA crosslinking and recombination-activating genes 1/2 (RAG1/2) are required for oncogenic splicing in acute lymphoblastic leukemia.
Cancer Commun (Lond), 41, 2021
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2JZ1
 | | DSX_long | | Descriptor: | Protein doublesex | | Authors: | Yang, Y, Zhang, W, Bayrer, J.R, Weiss, M.A. | | Deposit date: | 2007-12-21 | | Release date: | 2008-01-08 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Doublesex and the Regulation of Sexual Dimorphism in Drosophila melanogaster: STRUCTURE, FUNCTION, AND MUTAGENESIS OF A FEMALE-SPECIFIC DOMAIN.
J.Biol.Chem., 283, 2008
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