7VLM
| crystal structure of anti-CRISPR protein AcrIIA18 | Descriptor: | ACETATE ION, DI(HYDROXYETHYL)ETHER, H2C7, ... | Authors: | Zhang, H, Wang, X.S, Li, X.Z. | Deposit date: | 2021-10-04 | Release date: | 2021-12-01 | Last modified: | 2023-07-05 | Method: | X-RAY DIFFRACTION (1.38 Å) | Cite: | Inhibition mechanisms of CRISPR-Cas9 by AcrIIA17 and AcrIIA18 Nucleic Acids Res., 50, 2022
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3GBF
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3H0Q
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3H0J
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3HFJ
| Bacillus anthracis nicotinate mononucleotide adenylytransferase (nadD) in complex with inhibitor CID 3289443 | Descriptor: | 3-amino-N-(3-fluorophenyl)-6-thiophen-2-ylthieno[2,3-b]pyridine-2-carboxamide, CALCIUM ION, Nicotinate (Nicotinamide) nucleotide adenylyltransferase | Authors: | Zhang, H, Huang, N, Eyobo, Y. | Deposit date: | 2009-05-11 | Release date: | 2009-09-08 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | Targeting NAD biosynthesis in bacterial pathogens: Structure-based development of inhibitors of nicotinate mononucleotide adenylyltransferase NadD. Chem.Biol., 16, 2009
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5V2A
| Crystal structure of Fab H7.167 in complex with influenza virus hemagglutinin from A/Shanghai/02/2013 (H7N9) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of H7.167 antibody, Hemagglutinin, ... | Authors: | Zhang, H, Zhu, X, Wilson, I.A. | Deposit date: | 2017-03-03 | Release date: | 2017-04-05 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (4.656 Å) | Cite: | H7N9 influenza virus neutralizing antibodies that possess few somatic mutations. J. Clin. Invest., 126, 2016
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5W42
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6M10
| Crystal structure of PA4853 (Fis) from Pseudomonas aeruginosa | Descriptor: | Putative Fis-like DNA-binding protein | Authors: | Zhang, H, Gao, Z, Zhou, J, Dong, Y. | Deposit date: | 2020-02-24 | Release date: | 2020-05-13 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.985 Å) | Cite: | Crystal structure of the nucleoid-associated protein Fis (PA4853) from Pseudomonas aeruginosa. Acta Crystallogr.,Sect.F, 76, 2020
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8FK2
| The N-terminal VicR from Streptococcus mutans | Descriptor: | Putative response regulator CovR VicR-like protein | Authors: | Zhang, H, Wu, H. | Deposit date: | 2022-12-20 | Release date: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | Small Molecule Attenuates Bacterial Virulence by Targeting Conserved Response Regulator. Mbio, 14, 2023
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3S6T
| Crystal Structure of insect beta-N-acetyl-D-hexosaminidase OfHex1 V327G complexed with PUGNAc | Descriptor: | N-acetylglucosaminidase, O-(2-ACETAMIDO-2-DEOXY D-GLUCOPYRANOSYLIDENE) AMINO-N-PHENYLCARBAMATE | Authors: | Zhang, H, Liu, T, Yang, Q, Shen, X. | Deposit date: | 2011-05-26 | Release date: | 2012-04-11 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Active-pocket size differentiating insectile from bacterial chitinolytic beta-N-acetyl-D-hexosaminidases. Biochem.J., 438, 2011
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7WEU
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7WET
| Crystal structure of Peroxiredoxin I in complex with the inhibitor Cela | Descriptor: | (2R,4aS,6aS,12bR,14aS,14bR)-10-hydroxy-2,4a,6a,9,12b,14a-hexamethyl-11-oxo-1,2,3,4,4a,5,6,6a,11,12b,13,14,14a,14b-tetradecahydropicene-2-carboxylic acid, Peroxiredoxin-1 | Authors: | Zhang, H, Luo, C. | Deposit date: | 2021-12-24 | Release date: | 2022-12-28 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | Celastrol suppresses colorectal cancer via covalent targeting peroxiredoxin 1. Signal Transduct Target Ther, 8, 2023
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7CQZ
| crystal structure of mouse FAM46C (TENT5C) | Descriptor: | CHLORIDE ION, GLYCEROL, Terminal nucleotidyltransferase 5C | Authors: | Hu, J.L, Zhang, H, Gao, S. | Deposit date: | 2020-08-12 | Release date: | 2021-06-09 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.34969759 Å) | Cite: | Structural and functional characterization of multiple myeloma associated cytoplasmic poly(A) polymerase FAM46C. Cancer Commun (Lond), 41, 2021
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7W0S
| TRIM7 in complex with C-terminal peptide of 2C | Descriptor: | DI(HYDROXYETHYL)ETHER, E3 ubiquitin-protein ligase TRIM7, GLYCEROL, ... | Authors: | Zhang, H, Liang, X, Li, X.Z. | Deposit date: | 2021-11-18 | Release date: | 2022-08-10 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | A C-terminal glutamine recognition mechanism revealed by E3 ligase TRIM7 structures. Nat.Chem.Biol., 18, 2022
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7W0T
| TRIM7 in complex with C-terminal peptide of 2C | Descriptor: | E3 ubiquitin-protein ligase TRIM7, peptide | Authors: | Zhang, H, Liang, X, Li, X.Z. | Deposit date: | 2021-11-18 | Release date: | 2022-08-10 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.57 Å) | Cite: | A C-terminal glutamine recognition mechanism revealed by E3 ligase TRIM7 structures. Nat.Chem.Biol., 18, 2022
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7W0Q
| TRIM7 in complex with C-terminal peptide of 2C | Descriptor: | E3 ubiquitin-protein ligase TRIM7, peptide | Authors: | Zhang, H, Liang, X, Li, X.Z. | Deposit date: | 2021-11-18 | Release date: | 2022-08-10 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | A C-terminal glutamine recognition mechanism revealed by E3 ligase TRIM7 structures. Nat.Chem.Biol., 18, 2022
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7X1N
| Crystal structure of MEF2D-MRE complex | Descriptor: | DNA (5'-D(P*AP*AP*CP*TP*AP*TP*TP*TP*AP*TP*AP*AP*G)-3'), DNA (5'-D(P*TP*CP*TP*TP*AP*TP*AP*AP*AP*TP*AP*GP*T)-3'), Myocyte enhancer factor 2D/deleted in azoospermia associated protein 1 fusion protein | Authors: | Zhang, H, Zhang, M, Wang, Q.Q, Chen, Z, Chen, S.J, Meng, G. | Deposit date: | 2022-02-24 | Release date: | 2022-05-25 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.315 Å) | Cite: | Functional, structural, and molecular characterizations of the leukemogenic driver MEF2D-HNRNPUL1 fusion. Blood, 140, 2022
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7X6Z
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7X70
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7X6Y
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7XND
| Crystal structure of Phosphomevalonate kinase from Silkworm | Descriptor: | GLYCEROL, Phosphomevalonate kinase | Authors: | Guo, P.C, Zhang, H. | Deposit date: | 2022-04-28 | Release date: | 2023-05-03 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural insights into the substrate binding of phosphomevalonate kinase from the silkworm, Bombyx mori. Insect Biochem.Mol.Biol., 150, 2022
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7X7S
| Solution structure of human adenylate kinase 1 (hAK1) | Descriptor: | Adenylate kinase isoenzyme 1 | Authors: | Zhang, H. | Deposit date: | 2022-03-10 | Release date: | 2022-05-11 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | ADP-Induced Conformational Transition of Human Adenylate Kinase 1 Is Triggered by Suppressing Internal Motion of alpha 3 alpha 4 and alpha 7 alpha 8 Fragments on the ps-ns Timescale. Biomolecules, 12, 2022
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7JR7
| Cryo-EM structure of ABCG5/G8 in complex with Fab 2E10 and 11F4 | Descriptor: | ATP-binding cassette sub-family G member 5, ATP-binding cassette sub-family G member 8, Fab 11F4 heavy chain, ... | Authors: | Huang, C.S, Yu, X, Min, X, Wang, Z, Zhang, H. | Deposit date: | 2020-08-11 | Release date: | 2021-04-07 | Last modified: | 2021-05-12 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Cryo-EM structure of ABCG5/G8 in complex with modulating antibodies Commun Biol, 4, 2021
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7X32
| Crystal structure of E. coli NfsB in complex with berberine | Descriptor: | BERBERINE, DIMETHYL SULFOXIDE, Dihydropteridine reductase, ... | Authors: | Zhang, H, Wen, H.Y. | Deposit date: | 2022-02-27 | Release date: | 2022-10-12 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.829 Å) | Cite: | Structural basis for the transformation of the traditional medicine berberine by bacterial nitroreductase. Acta Crystallogr D Struct Biol, 78, 2022
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1NUR
| CRYSTAL STRUCTURE OF HUMAN CYTOSOLIC NMN/NaMN ADENYLYLTRANSFERASE | Descriptor: | FKSG76, SULFATE ION | Authors: | Zhang, X, Kurnasov, O.V, Karthikeyan, S, Grishin, N.V, Osterman, A.L, Zhang, H. | Deposit date: | 2003-02-01 | Release date: | 2003-06-03 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | STRUCTURAL CHARACTERIZATION OF A HUMAN CYTOSOLIC NMN/NaMN
ADENYLYLTRANSFERASE AND IMPLICATION IN HUMAN NAD BIOSYNTHESIS J.Biol.Chem., 278, 2003
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