8SIQ
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![BU of 8siq by Molmil](/molmil-images/mine/8siq) | |
1CA5
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![BU of 1ca5 by Molmil](/molmil-images/mine/1ca5) | INTERCALATION SITE OF HYPERTHERMOPHILE CHROMOSOMAL PROTEIN SSO7D/SAC7D BOUND TO DNA | Descriptor: | 5'-D(*GP*TP*GP*AP*TP*CP*AP*C)-3', CHROMOSOMAL PROTEIN SAC7D | Authors: | Su, S, Gao, Y.-G, Robinson, H, Shriver, J.W, Wang, A.H.-J. | Deposit date: | 1999-02-23 | Release date: | 2000-02-23 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structures of the chromosomal proteins Sso7d/Sac7d bound to DNA containing T-G mismatched base-pairs J.Mol.Biol., 303, 2000
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8DR4
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![BU of 8dr4 by Molmil](/molmil-images/mine/8dr4) | Open state of RFC:PCNA bound to a 3' ss/dsDNA junction (DNA2) without NTD | Descriptor: | DNA (5'-D(P*AP*AP*GP*GP*GP*GP*GP*GP*GP*GP*GP*G)-3'), DNA (5'-D(P*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*TP*TP*T)-3'), DNA (5'-D(P*CP*CP*CP*CP*CP*CP*GP*GP*CP*CP*CP*CP*CP*CP*CP*GP*GP*C)-3'), ... | Authors: | Schrecker, M, Hite, R.K. | Deposit date: | 2022-07-20 | Release date: | 2022-08-17 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (2.45 Å) | Cite: | Multistep loading of a DNA sliding clamp onto DNA by replication factor C. Elife, 11, 2022
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8DR7
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![BU of 8dr7 by Molmil](/molmil-images/mine/8dr7) | Open state of RFC:PCNA bound to a nicked dsDNA | Descriptor: | DNA (26-MER), DNA (5'-D(P*AP*GP*GP*GP*GP*GP*GP*GP*GP*GP*G)-3'), DNA (5'-D(P*GP*GP*CP*CP*CP*CP*CP*CP*CP*GP*GP*C)-3'), ... | Authors: | Schrecker, M, Hite, R.K. | Deposit date: | 2022-07-20 | Release date: | 2022-08-17 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Multistep loading of a DNA sliding clamp onto DNA by replication factor C. Elife, 11, 2022
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8DR3
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![BU of 8dr3 by Molmil](/molmil-images/mine/8dr3) | Closed state of RFC:PCNA bound to a 3' ss/dsDNA junction (DNA2) with NTD | Descriptor: | DNA (5'-D(P*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*TP*TP*T)-3'), DNA (5'-D(P*CP*CP*CP*CP*CP*CP*GP*GP*CP*CP*CP*CP*CP*CP*CP*GP*GP*C)-3'), DNA (5'-D(P*TP*TP*AP*GP*GP*GP*GP*GP*GP*GP*GP*GP*A)-3'), ... | Authors: | Schrecker, M, Hite, R.K. | Deposit date: | 2022-07-20 | Release date: | 2022-08-17 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (2.2 Å) | Cite: | Multistep loading of a DNA sliding clamp onto DNA by replication factor C. Elife, 11, 2022
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8DR5
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![BU of 8dr5 by Molmil](/molmil-images/mine/8dr5) | Open state of RFC:PCNA bound to a 3' ss/dsDNA junction (DNA2) with NTD | Descriptor: | DNA (5'-D(P*AP*GP*GP*GP*GP*GP*GP*GP*GP*GP*G)-3'), DNA (5'-D(P*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*TP*TP*T)-3'), DNA (5'-D(P*GP*GP*CP*CP*CP*CP*CP*CP*CP*GP*GP*C)-3'), ... | Authors: | Schrecker, M, Hite, R.K. | Deposit date: | 2022-07-20 | Release date: | 2022-08-17 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (2.76 Å) | Cite: | Multistep loading of a DNA sliding clamp onto DNA by replication factor C. Elife, 11, 2022
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8DR1
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![BU of 8dr1 by Molmil](/molmil-images/mine/8dr1) | Consensus closed state of RFC:PCNA bound to a 3' ss/dsDNA junction (DNA2) | Descriptor: | DNA (5'-D(P*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*TP*TP*T)-3'), DNA (5'-D(P*CP*CP*CP*CP*CP*CP*GP*GP*CP*CP*CP*CP*CP*CP*CP*GP*GP*C)-3'), DNA (5'-D(P*TP*TP*AP*GP*GP*GP*GP*GP*GP*GP*GP*GP*A)-3'), ... | Authors: | Schrecker, M, Hite, R.K. | Deposit date: | 2022-07-20 | Release date: | 2022-08-17 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (2.14 Å) | Cite: | Multistep loading of a DNA sliding clamp onto DNA by replication factor C. Elife, 11, 2022
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8DQW
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![BU of 8dqw by Molmil](/molmil-images/mine/8dqw) | |
7YXW
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![BU of 7yxw by Molmil](/molmil-images/mine/7yxw) | Structure of the p22phox A200G mutant in complex with p47phox peptide | Descriptor: | Cytochrome b-245 light chain, Neutrophil cytosol factor 1 | Authors: | Cukier, C.D, Vuillard, L.M, Komjati, B, Szlavik, Z. | Deposit date: | 2022-02-16 | Release date: | 2022-03-30 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Targeting NOX2 via p47/phox-p22/phox Inhibition with Novel Triproline Mimetics Acs Med.Chem.Lett., 13, 2022
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8SDF
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![BU of 8sdf by Molmil](/molmil-images/mine/8sdf) | |
2OSN
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![BU of 2osn by Molmil](/molmil-images/mine/2osn) | |
7WN8
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![BU of 7wn8 by Molmil](/molmil-images/mine/7wn8) | Crystal structure of antibody (BC31M5) binds to CD47 | Descriptor: | BC31M5 Fab Heavy chain, BC31M5 Fab Light chain, Leukocyte surface antigen CD47, ... | Authors: | Li, Y, Wang, W, Sui, J, Zhang, S. | Deposit date: | 2022-01-17 | Release date: | 2023-01-25 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | A pH-dependent anti-CD47 antibody that selectively targets solid tumors and improves therapeutic efficacy and safety. J Hematol Oncol, 16, 2023
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8E3R
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![BU of 8e3r by Molmil](/molmil-images/mine/8e3r) | Human PU.1 ETS-Domain (165-270) Bound to d(AATAAAAGGAAGTGGG) | Descriptor: | DNA (5'-D(*AP*AP*TP*AP*AP*AP*AP*GP*GP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*TP*TP*TP*TP*AP*T)-3'), Transcription factor PU.1 | Authors: | Terrell, J.R, Poon, G.M.K. | Deposit date: | 2022-08-17 | Release date: | 2023-07-05 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | DNA selection by the master transcription factor PU.1. Cell Rep, 42, 2023
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8E4H
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![BU of 8e4h by Molmil](/molmil-images/mine/8e4h) | Human PU.1 ETS-Domain (165-270) Bound to d(AATAAGAGGAAGTGGG) | Descriptor: | DNA (5'-D(*AP*AP*TP*AP*AP*GP*AP*GP*GP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*TP*CP*TP*TP*AP*T)-3'), Transcription factor PU.1 | Authors: | Terrell, J.R, Poon, G.M.K. | Deposit date: | 2022-08-18 | Release date: | 2023-07-05 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.39 Å) | Cite: | DNA selection by the master transcription factor PU.1. Cell Rep, 42, 2023
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8E3K
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![BU of 8e3k by Molmil](/molmil-images/mine/8e3k) | Human PU.1 ETS-Domain (165-270) Bound to d(AATAAGCGGAAGTGGG) | Descriptor: | DNA (5'-D(*AP*AP*TP*AP*AP*GP*CP*GP*GP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*GP*CP*TP*TP*AP*T)-3'), SODIUM ION, ... | Authors: | Terrell, J.R, Poon, G.M.K. | Deposit date: | 2022-08-17 | Release date: | 2023-07-05 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.28 Å) | Cite: | DNA selection by the master transcription factor PU.1. Cell Rep, 42, 2023
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8E5Y
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![BU of 8e5y by Molmil](/molmil-images/mine/8e5y) | |
8EE9
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![BU of 8ee9 by Molmil](/molmil-images/mine/8ee9) | Human PU.1 ETS-Domain (165-270) Bound to d(AATAAAAGGAATGGGG) | Descriptor: | DNA (5'-D(*AP*AP*TP*AP*AP*AP*AP*GP*GP*AP*AP*TP*GP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*CP*AP*TP*TP*CP*CP*TP*TP*TP*TP*AP*T)-3'), Transcription factor PU.1 | Authors: | Terrell, J.R, Poon, G.M.K. | Deposit date: | 2022-09-06 | Release date: | 2023-07-05 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.22 Å) | Cite: | DNA selection by the master transcription factor PU.1. Cell Rep, 42, 2023
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8EBH
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![BU of 8ebh by Molmil](/molmil-images/mine/8ebh) | Human PU.1 ETS-Domain (165-270) Bound to d(AATAAGCGGAATGGGG) | Descriptor: | DNA (5'-D(*AP*AP*TP*AP*AP*GP*CP*GP*GP*AP*AP*TP*GP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*CP*AP*TP*TP*CP*CP*GP*CP*TP*TP*AP*T)-3'), Transcription factor PU.1 | Authors: | Terrell, J.R, Poon, G.M.K. | Deposit date: | 2022-08-31 | Release date: | 2023-07-05 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.33 Å) | Cite: | DNA selection by the master transcription factor PU.1. Cell Rep, 42, 2023
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6B7G
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![BU of 6b7g by Molmil](/molmil-images/mine/6b7g) | Solution NMR structure of BCoR in complex with AF9 (BCoR-AF9) | Descriptor: | BCL-6 corepressor, Protein AF-9 | Authors: | Schmidt, C.R, Kuntimaddi, A, Leach, B.I, Bushweller, J.H. | Deposit date: | 2017-10-04 | Release date: | 2018-10-10 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | BCOR Binding to MLL-AF9 Is Essential for Leukemia via Altered EYA1, SIX, and MYC Activity. Blood Cancer Discov, 1, 2020
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7MPG
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![BU of 7mpg by Molmil](/molmil-images/mine/7mpg) | |
7MMN
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![BU of 7mmn by Molmil](/molmil-images/mine/7mmn) | |
5FR6
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![BU of 5fr6 by Molmil](/molmil-images/mine/5fr6) | The structure of polycomb ULD complex | Descriptor: | POLYCOMB COMPLEX PROTEIN BMI-1 | Authors: | Gray, F, Cho, H.J, Cierpicki, T. | Deposit date: | 2015-12-15 | Release date: | 2016-11-16 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | Bmi1 Regulates Prc1 Architecture and Activity Through Homo-and Hetero-Oligomerization Nat.Commun., 7, 2016
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3CLB
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![BU of 3clb by Molmil](/molmil-images/mine/3clb) | Structure of bifunctional TcDHFR-TS in complex with TMQ | Descriptor: | 1,2-ETHANEDIOL, DHFR-TS, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | Schormann, N, Senkovich, O, Chattopadhyay, D. | Deposit date: | 2008-03-18 | Release date: | 2009-01-06 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structure-based approach to pharmacophore identification, in silico screening, and three-dimensional quantitative structure-activity relationship studies for inhibitors of Trypanosoma cruzi dihydrofolate reductase function. Proteins, 73, 2008
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6BGL
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![BU of 6bgl by Molmil](/molmil-images/mine/6bgl) | Doubly PafE-capped 20S core particle in Mycobacterium tuberculosis | Descriptor: | Bacterial proteasome activator, Proteasome subunit alpha, Proteasome subunit beta | Authors: | Li, H, Hu, K. | Deposit date: | 2017-10-28 | Release date: | 2018-02-14 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Proteasome substrate capture and gate opening by the accessory factor PafE fromMycobacterium tuberculosis. J. Biol. Chem., 293, 2018
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6BGO
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![BU of 6bgo by Molmil](/molmil-images/mine/6bgo) | Singly PafE-capped 20S CP in Mycobacterium tuberculosis | Descriptor: | Bacterial proteasome activator, Proteasome subunit alpha, Proteasome subunit beta | Authors: | Li, H, Hu, K. | Deposit date: | 2017-10-29 | Release date: | 2018-02-14 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Proteasome substrate capture and gate opening by the accessory factor PafE fromMycobacterium tuberculosis. J. Biol. Chem., 293, 2018
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